Zusammenfassung
Endometriose, die wahrscheinlich häufigste benigne Erkrankung in der Frauenheilkunde, bedeutet für die betroffenen Frauen eine oftmals unerträgliche Zeit von etwa 8–10 Jahren bis zur Diagnosesicherung. Ein intensives Gespräch mit der Patientin, eine genaue gynäkologische Spiegel- und Tastuntersuchung und eine Transvaginalsonografie ermöglichen die Diagnose. Die Diagnose bedarf der Absicherung. Hier kann die MRT-Technologie einen wichtigen Beitrag liefern. Einen spezifischen Marker aus Blut oder Serum gibt es bis dato nicht – trotz intensiver Beforschung einer solchen sicherlich eleganten Option. Ob es einen hinreichend beweiskräftigen Marker geben wird und ob ein solcher wirklich sinnvoll sein kann, bleibt abzuwarten. Bis dato gilt immer noch die operative Abklärung per laparoscopiam als Goldstandard.
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Literatur
Adamson GD, Pasta DJ (2010) Endometriosis fertility index: the new, validated endometriosis staging system. Fertil Steril 94:1609–1615
Alborzi S, Momtahan M, Parsanezhad ME, Dehbashi S, Zolghadri J, Alborzi S (2004) A prospective, randomized study comparing laparoscopic ovarian cystectomy versus fenestration and coagulation in patients with endometriomas. Fertil Steril 82:1633–1637
ASRM classification of endometriosis (1996) Fertil Steril 67:817–821
Balasch J, Creus M, Fabregues F et al (1996) Visible and non-visible endometriosis at laparoscopy in fertile and infertile women and in patients with chronic pelvic pain: a prospective study. Hum Reprod 11:387–391
Ballester M, Roman H, Mathieu E, Touleimat S, Belghiti J, Darai E (2017) Prior colorectal surgery for endometriosis-associated infertility improves ICSI-IVF outcomes: results from expert centres. Eur J Obstet Gynecol Reprod Biol 209:95–99
Benschop L, Farquhar C, van der Poel N, Heineman MJ (2010) Interventions for women with endometrioma prior to assisted reproductive technology. Cochrane Database Syst Rev (11):CD008571
Bianchi PHM, Pereira RMA, Zanatta A, Alegretti JR, Motta ELA, Serafini PC (2009) Extensive excision of deep infiltrative endometriosis before in vitro fertilization significantly improves pregnancy rates. J Minim Invasive Gynecol 16:174–180
Brinton LA, Gridley G, Persson I et al (1997) Cancer risk after a hospital discharge diagnosis of endometriosis. Am J Obstet Gynecol 176:572–579. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=15200778&query_hl=16&itool=pubmed_DocSum. Zugegriffen am 06.09.2019
Brosens I, Puttemans P, Campo R et al (2004) Diagnosis of endometriosis: pelvic endoscopy and imaging techniques. Best Pract Res Clin Obstet Gynaecol 18:285–303
Buchweitz O, Staebler A, Tio J et al (2006) Detection of peritoneal endometriotic lesions by autofluorescence laparoscopy. Am J Obstet Gynecol 195:949–954
Daraï E, Lesieur B, Dubernard G, Rouzier R, Bazot M, Ballester M (2011) Fertility after colorectal resection for endometriosis: results of a prospective study comparing laparoscopy with open surgery. Fertil Steril 95:1903–1908
Darwish B, Roman H (2016) Surgical treatment of deep infiltrating rectal endometriosis: in favor of less aggressive surgery. Am J Obstet Gynecol 215(2):195–200
Demco L (2004) Laparoscopic spectral analysis of endometriosis. J Am Assoc Gynecol Laparosc 11:219–222
D’Hooghe TM (2003) Invisible microscopic endometriosis: how wrong is the sampson hypothesis of retrograde menstruation to explain the pathogenesis of endometriosis? Gynecol Obstet Investig 55:61–62
Dinulescu DM, Ince TA, Quade BJ et al (2005) Role of K-Ras and Pten in the development of mouse models of endometriosis and endometriod ovarian cancer. Nat Med 11:63–70
Donnez J, Nisolle M, Gillet N, Smets M, Bassil S, Casanas-Roux F (1996) Large ovarian endometriomas. Hum Reprod 11:641–646
Douay-Hauser N, Yazbeck C, Walker F, Luton D, Madelenat P, Koskas M (2011) Infertile women with deep and intraperitoneal endometriosis: comparison of fertility outcome according to the extent of surgery. J Minim Invasive Gynecol 18:622–628
Dunselman GA, Vermeulen N, Becker C, Calhaz-Jorge C, D’hooghe T, De Bie B, Heikinheimo O, Horne AW, Kiesel L, Nap A, Prentice A, Saridogan E, Soriano D, Nelen W, European Society of Human Reproduction and Embryology (2014) ESHRE guideline: management of women with endometriosis. Hum Reprod 29(3):400–412. https://doi.org/10.1093/humrep/det457. Epub 2014 Jan 15
Evers JL, Dunselman GA, Groothuis P (2005) Now you see them, now you don’t. Fertil Steril 84:31–32; discussion 38–9. Review
Hart RJ, Hickey M, Maouris P, Buckett W (2008) Excisional surgery versus ablative surgery for ovarian endometriomata. Cochrane Database Syst Rev (2):CD004992. https://doi.org/10.1002/14651858
Hillemanns P, Weingandt H, Stepp H et al (2000) Assessment of 5-aminolevulinic acid-induced porphyrin fluorescence in patients with peritoneal endometriosis. Am J Obstet Gynecol 183:52–57
Huffman JW (1981) Endometriosis in young teen-age girls. Pediatr Ann 10:44–49
Jacobson TZ, Duffy JMN, Barlow D, Farquhar C, Koninckx PR, Olive D (2010) Laparoscopic surgery for subfertility associated with endometriosis. Editorial Group: Cochrane Menstrual Disorders and Subfertility Group. Cochrane Database Syst Rev (1):CD001398. https://doi.org/10.1002/14651858.CD001398.pub2
Kang SB, Chung HH, Lee HP et al (2006) Impact of diagnostic laparoscopy on the management of chronic pelvic pain. Surg Endosc 14: 916–919
Kohl Schwartz AS, Wölfler MM, Mitter V, Rauchfuss M, Haeberlin F, Eberhard M, von Orelli S, Imthurn B, Imesch P, Fink D, Leeners B (2017) Endometriosis, especially mild disease: a risk factor for miscarriages. Fertil Steril 108(5):806–814.e2. https://doi.org/10.1016/j.fertnstert.2017.08.025
Kupker W, van der Linde H, Loning M et al (2004) Laparoscopic autofluorescence imaging of endometriosis. Fertil Steril 82:S72–S73
Kyama CM, Debrock S, Mwenda JM et al (2003) Potential involvement of the immune system in the development of endometriosis. Reprod Biol Endocrinol 1:121
Malik E, Berg C, Meyhofer-Malik A et al (2000) Fluorescence diagnosis of endometriosis using 5-aminolevulinic acid. Surg Endosc 14:452–455
Marcoux S, Maheux R, Bérubé S (1997) Laparoscopic surgery in infertile women with minimal or mild endometriosis. Canadian Collaborative Group on Endometriosis. N Engl J Med 337:217–222
Matalliotakis I, Mahutte NG, Koukoura O, Arici A (2006) Endometriosis-associated stage IA clear cell ovarian carcinoma in a woman with IVF-ET treatments in the Yale series. Arch Gynecol Obstet 274:184–186
Medina MG, Lebovic DI (2009) Endometriosis – associated nerve fibers and pain. Acta Obstet Gynecol Scand 88:968–975
Melin A, Sparen P, Persson I (2006) Endometriosis and the risk of cancer with special emphasis on ovarian cancer. Hum Reprod 21:1237–1242
Missmer SA, Hankinson SE, Spiegelman D, Barbieri RL, Marshall LM, Hunter DJ (2004) Incidence of laparoscopically confirmed endometriosis by demographic, anthropometric, and lifestyle factors. Am J Epidemiol 160(8):784–796
Moini A, Riazi K, Amid V, Ashrafi M, Tehraninejad E, Madani T, Owj M (2005) Endometriosis may contribute to oocyte retrieval-induced pelvic inflammatory disease: report of eight cases. J Assist Reprod Genet 22:307–309
Murphy AA, Green WR, Bobbie D et al (1986) Unsuspected endometriosis documented by scanning electronmicroscopy in visualy normal peritoneum. Fertil Steril 46:522–524
Nezhat C, Crowgey S, Nezhat F (1989) Videolaseroscopy for the treatment of endometriosis associated with infertility. Fertil Steril 51:237–240
Opøien HK, Fedorcsak P, Byholm T, Tanbo T (2011) Complete surgical removal of minimal and mildendometriosis improves outcome of subsequent IVF/ICSI treatment. Reprod Biomed Online 23:389–395
Pagidas K, Falcone T, Hemmings R, Miron P (1996) Comparison of reoperation for moderate (stage III) and severe (stage IV) endometriosis-related infertility with in vitro fertilization-embryo transfer. Fertil Steril 65:791–795
Parazzini F (1999) Ablation of lesions or no treatment in minimal-mild endometriosis in infertile women: a randomized trial. Gruppo Italiano per lo Studio dell’Endometriosi. Hum Reprod 14:1332–1334
Peirce CL, Templeman C, Rossing MA (2012) On behalf of the Ovarian cancer Association Consortium. Association between endometriosis and risk of histological subtypes of ovarian cancer: a pooled analysis of case-control studies. Lancet Oncol 13:385–394
Pellicer A, Albert C, Garrido N et al (2000) The pathophysiology of endometriosis – associated infertility: follicular environment and embryo quality. J Reprod Fertil Suppl 55:109–119
Redwine DB (1999) Ovarian endometriosis: a marker for more extensive pelvic and intestinal disease. Fertil Steril 72:310–315
Rickes D, Nickel I, Kropf S, Kleinstein J (2002) Increased pregnancy rates after ultralong postoperative therapy with gonadotropin-releasing hormone analogs in patients with endometriosis. Fertil Steril 78:757–762
Sallam H, Garcia-Velasco J, Dias S, Arici A (2006) Long-term pituitary down-regulation before in vitro fertilization (IVF) for women with endometriosis. Cochrane Database Syst Rev (1):CD004635
Sampson JA (1925) Endometrial carcinoma of ovary arisingin endometrial tissue in that organ. Arch Surg 10:1–72
Sinaii N, Ceary SD, Ballweg ML (2002) High rates of autoimmune and endocrine disorders, fibromyalgia, chronic fatigue syndrome and atopic diseases among women with endometriosis: a survey analysis. Hum Reprod 17:2715–2724
Stepniewska A, Pomini P, Bruni F, Mereu L, Ruffo G, Ceccaroni M, Scioscia M, Guerriero M, Minelli L (2009) Laparoscopic treatment of bowel endometriosis in infertile women. Hum Reprod 24:1619–1625
Tsoumpou I, Kyrgiou M, Gelbaya TA, Nardo LG (2009) The effect of surgical treatment for endometrioma on in vitro fertilization outcomes: a systematic review and meta-analysis. Fertil Steril 92:75–87
Tuttlies F, Keckstein J, Ulrich U et al (2005) ENZIAN score: a classification of deep infiltrating endometriosis. Zentralbl Gynakol 127:275–281
Vercellini P, Fedele L, Aimi G, De Giorgi O, Consonni D, Crosignani PG (2006) Reproductive performance, pain recurrence and disease relapse after conservative surgical treatment for endometriosis: the predictive value of the current classification system. Hum Reprod 21:2679–2685
Wolfram F, Riedlinger J, Weichbrodt M et al (2010) Sentinel lymph node labeling of patients with deep infiltrating rectovaginal endometriosis – does this make sense? J Endometr 2:33–40
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Küpker, W., Agic, A. (2020). Endometriose. In: Diedrich, K., Ludwig, M., Griesinger, G. (eds) Reproduktionsmedizin. Springer Reference Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-57636-6_35
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