Zusammenfassung
Eine persistierende HPV-Infektion mit Hochrisikosubtypen ist der wichtigste Risikofaktor für die Entstehung des Zervixkarzinoms. Die prophylaktische Impfung gegen HPV 16 und 18 kann die Rate an Zervixkarzinomen um ca. 70 % reduzieren. Im Frühstadium (IB1 und IIA) stellen die radikale Hysterektomie oder die Radiotherapie des Beckens den Therapiestandard dar. Die Kombination einer Strahlen- mit Chemotherapie ist die Standardbehandlung bei den fortgeschrittenen Stadien Ib2 und IIb–IV. Rezidive treten bevorzugt im Becken auf.
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Petru, E., Winter, R., Bader, A., Kapp, K.K., Reich, O. (2019). Maligne Tumoren der Cervix uteri. In: Petru, E., Fink, D., Köchli, O., Loibl, S. (eds) Praxisbuch Gynäkologische Onkologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-57430-0_5
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