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Maligne Tumoren der Vulva

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Praxisbuch Gynäkologische Onkologie

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Zusammenfassung

Das Vulvakarzinom ist selten und tritt bevorzugt zwischen dem 60. und 70. Lebensjahr auf. Im Vordergrund der Therapie stehen die weite Exzision des Primärtumors im Gesunden und die histologische Beurteilung der inguinalen Lymphknoten. Die systematische inguinale Lymphadenektomie wird bei T1- und T2-Tumoren bei Vorliegen negativer Sentinel-Lymphknoten zunehmend von einer alleinigen Sentinel-Lymphknoten-Biopsie abgelöst. Diese weist eine Treffsicherheit von > 95 % auf Ca. 70 % der Patientinnen mit Vulvakarzinom kann so eine systematische inguinale Lymphadenektomie, die mit einer signifikanten Morbidität wie Lymphödemen behaftet ist, erspart werden. Eine primäre Radio-(Chemo-)Therapie kann bei großen Primärtumoren und/oder inguinalen Lymphknotenmetastasen häufig den Tumor in Remission bringen und damit exenterative Therapien umgehen.

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Authors and Affiliations

  1. Universitätsklinik für Frauenheilkunde und Geburtshilfe, Medizinische Universität Graz, Graz, Österreich

    Karl Tamussino, Gerda Trutnovsky & Edgar Petru

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  1. Karl Tamussino
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  2. Gerda Trutnovsky
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  3. Edgar Petru
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Correspondence to Karl Tamussino .

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Editors and Affiliations

  1. Universitätsklinik für Frauenheilkunde und Geburtshilfe, Medizinische Universität Graz, Graz, Austria

    Edgar Petru

  2. Klinik für Gynäkologie, UniversitätsSpital Zürich, Zürich, Switzerland

    Daniel Fink

  3. Gynäkologisch-onkologische Praxis, BrustCentrum, Privatklinik Zürich-Bethanien, Zürich, Switzerland

    Ossi R. Köchli

  4. German Breast Group Forschungs GmbH, Neu-Isenburg, Germany

    Sibylle Loibl

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Tamussino, K., Trutnovsky, G., Petru, E. (2019). Maligne Tumoren der Vulva. In: Petru, E., Fink, D., Köchli, O., Loibl, S. (eds) Praxisbuch Gynäkologische Onkologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-57430-0_12

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  • DOI: https://doi.org/10.1007/978-3-662-57430-0_12

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