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Abstract: Revealing Hidden Potentials of the q-Space Signal in Breast Cancer

  • Paul Jaeger
  • Sebastian Bickelhaupt
  • Frederik Bernd Laun
  • Wolfgang Lederer
  • Daniel Heidi
  • Tristan Anselm Kuder
  • Daniel Paech
  • David Bonekamp
  • Alexander Radbruch
  • Stefan Delorme
  • Heinz-Peter Schlemmer
  • Franziska Steudle
  • Klaus Hermann Maier-Hein
Conference paper
Part of the Informatik aktuell book series (INFORMAT)

Zusammenfassung

Mammography screening for early detection of breast lesions currently suffers from high amounts of false positive findings, which result in unnecessary invasive biopsies. Diffusion-weighted MR images (DWI) can help to reduce many of these false-positive findings prior to biopsy. Current approaches estimate tissue properties by means of quantitative parameters taken from generative, biophysical models fit to the q-space signal under certain assumptions regarding noise and spatial homogeneity. This process is prone to fitting instability and partial information loss due to model simplicity.

Literatur

  1. 1.
    Jäger PF, Bickelhaupt S, Laun FB, et al.; Springer. Revealing hidden potentials of the q-space signal in breast cancer. Proc MICCAI. 2017; p. 664–671.Google Scholar

Copyright information

© Springer-Verlag GmbH Deutschland 2018

Authors and Affiliations

  • Paul Jaeger
    • 1
  • Sebastian Bickelhaupt
    • 2
  • Frederik Bernd Laun
    • 2
    • 3
  • Wolfgang Lederer
    • 4
  • Daniel Heidi
    • 5
  • Tristan Anselm Kuder
    • 6
  • Daniel Paech
    • 2
  • David Bonekamp
    • 2
  • Alexander Radbruch
    • 2
  • Stefan Delorme
    • 2
  • Heinz-Peter Schlemmer
    • 2
  • Franziska Steudle
    • 2
  • Klaus Hermann Maier-Hein
    • 1
  1. 1.Medical Image ComputingGerman Cancer Research Center (DKFZ)HeidelbergDeutschland
  2. 2.Department of RaiologyDKFZHeidelbergDeutschland
  3. 3.Institute of RadiologyUniversity Hospital ErlangenErlangenDeutschland
  4. 4.Radiological Practice at the ATOS ClinicHeidelbergDeutschland
  5. 5.Radiology Center Mannheim (RZM)MannheimDeutschland
  6. 6.Medical Physics in RadiologyDKFZHeidelbergDeutschland

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