Zusammenfassung
Narben können auf unterschiedlichen Wegen durch Verletzung der mittleren bis tiefen Dermis entstehen, etwa durch Operationen, Verletzungen, verschiedene entzündliche Hautkrankheiten oder auch spontan, ohne offensichtliche äußere Einflüsse. Meist gehen damit keine weiteren Beschwerden einher, in manchen Fällen kommt es jedoch zur Entstehung pathologischer Narbenformen wie etwa von linearen oder flächigen hypertrophen Narben oder Keloiden. Diese gehen oftmals mit quälenden Symptomen, wie Schmerzen oder Juckreiz und starken ästhetischen, funktionellen und psychosozialen Einschränkungen einher. Dies begründet die Notwendigkeit effektiver Narbentherapieoptionen. Aktuell kommen zur Narbentherapie eine Reihe von operativen und nicht-operativen Behandlungs- und Präventionsmaßnahmen zum Einsatz. Dazu zählt u. a. der Einsatz intraläsionaler Injektionstechniken mit kristallinen Kortikosteroiden oder 5-Fluorouracil, die Anwendung Silikon- oder Zwiebelextrakt-haltiger Wundauflagen und Gels, Drucktherapie sowie die chirurgische Exzision von Narbengewebe, die Spannungsreduktion durch Z- oder W-Plastiken, lokale und Fernlappenplastiken oder die Verwendung von Hauttransplantaten. In diesem Kapitel geht es um die wichtigsten Aspekte zum Thema Narbenbehandlung mittels Laser.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsLiteratur
Reinholz M, Poetschke J, Schwaiger H, Epple A, Ruzicka T, Gauglitz GG. The dermatology life quality index as a means to assess life quality in patients with different scar types. J Eur Acad Dermatol Venereol. 2015;29; 2112-2119
Gauglitz GG. Management of keloids and hypertrophic scars: current and emerging options. Clinical, cosmetic and investigational dermatology. 2013;6; 103-114
Poetschke J, Gauglitz GG. Current options for the treatment of pathological scarring. Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG. 2016;14; 467-477
Gangemi E, Gregori D, Berchialla P, et al. Epidemiology and risk factors for pathologic scarring after burn wounds. Archives of Facial Plastic Surgery. 2008;10; 93-102
Gauglitz GG, Korting HC, Pavicic T, Ruzicka T, Jeschke MG. Hypertrophic scarring and keloids: pathomechanisms and current and emerging treatment strategies. Molecular medicine (Cambridge, Mass). 2011;17; 113-125
Reinholz M, Schwaiger H, Heppt MV, Poetschke J, Tietze J, Epple A, et al. Comparison of Two Kinds of Lasers in the Treatment of Acne Scars. Facial plastic surgery : FPS. 2015;31; 523-531
Gauglitz GG, Reinholz M, Kaudewitz P, Schauber J, Ruzicka T. Treatment of striae distensae using an ablative Erbium: YAG fractional laser versus a 585-nm pulsed-dye laser. Journal of cosmetic and laser therapy: official publication of the European Society for Laser Dermatology. 2014;16; 117-119
Yamaguchi K, Suganuma N, Ohashi K. Quality of life evaluation in Japanese pregnant women with striae gravidarum: a cross-sectional study. BMC research notes. 2012;5; 450
Niessen FB, Spauwen PH, Schalkwijk J, Kon M. On the nature of hypertrophic scars and keloids: a review. Plastic and reconstructive surgery. 1999;104; 1435-1458
Slemp AE, Kirschner RE. Keloids and scars: a review of keloids and scars, their pathogenesis, risk factors, and management. Current opinion in pediatrics. 2006;18; 396-402
Tredget EE, Nedelec B, Scott PG, Ghahary A. Hypertrophic scars, keloids, and contractures. The cellular and molecular basis for therapy. The Surgical clinics of North America. 1997;77; 701-730
Bock O, Yu H, Zitron S, Bayat A, Ferguson MW, Mrowietz U. Studies of transforming growth factors beta 1-3 and their receptors I and II in fibroblast of keloids and hypertrophic scars. Acta dermato-venereologica. 2005;85; 216-220
Kose O, Waseem A. Keloids and hypertrophic scars: are they two different sides of the same coin? Dermatol Surg. 2008;34; 336-346
Szulgit G, Rudolph R, Wandel A, Tenenhaus M, Panos R, Gardner H. Alterations in fibroblast alpha1beta1 integrin collagen receptor expression in keloids and hypertrophic scars. The Journal of investigative dermatology. 2002;118; 409-415
Brown JJ, Bayat A. Genetic susceptibility to raised dermal scarring. Br J Dermatol. 2009;161; 8-18
Goodman GJ. Post-acne scarring: a short review of its pathophysiology. The Australasian journal of dermatology. 2001;42; 84-90
Stewart N, Lim AC, Lowe PM, Goodman G. Lasers and laser-like devices: part one. The Australasian journal of dermatology. 2013;54; 173-183
Dams SD, de Liefde-van Beest M, Nuijs AM, Oomens CW, Baaijens FP. Pulsed heat shocks enhance procollagen type I and procollagen type III expression in human dermal fibroblasts. Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI). 2010;16; 354-364
Helbig D, Paasch U. Molecular changes during skin aging and wound healing after fractional ablative photothermolysis. Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI). 2011;17; 119-128
Laubach HJ, Tannous Z, Anderson RR, Manstein D. Skin responses to fractional photothermolysis. Lasers Surg Med. 2006;38; 142-149
Manstein D, Herron GS, Sink RK, Tanner H, Anderson RR. Fractional photothermolysis: a new concept for cutaneous remodeling using microscopic patterns of thermal injury. Lasers Surg Med. 2004;34; 426-438
Qu L, Liu A, Zhou L, He C, Grossman PH, Moy RL, et al. Clinical and molecular effects on mature burn scars after treatment with a fractional CO(2) laser. Lasers Surg Med. 2012;44; 517-524
Nast A, Eming S, Fluhr J, Fritz K, Gauglitz G, Hohenleutner S, et al. German S2k guidelines for the therapy of pathological scars (hypertrophic scars and keloids). Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG. 2012;10; 747-762
Alster T. Laser scar revision: comparison study of 585-nm pulsed dye laser with and without intralesional corticosteroids. Dermatol Surg. 2003;29; 25-29
Dierickx C, Goldman MP, Fitzpatrick RE. Laser treatment of erythematous/hypertrophic and pigmented scars in 26 patients. Plastic and reconstructive surgery. 1995;95; 84-90; discussion 91-82
Cho SB, Lee JH, Lee SH, Lee SJ, Bang D, Oh SH. Efficacy and safety of 1064-nm Q-switched Nd:YAG laser with low fluence for keloids and hypertrophic scars. J Eur Acad Dermatol Venereol. 2010;24; 1070-1074
Bencini PL, Tourlaki A, Galimberti M, Longo C, Pellacani G, De Giorgi V, et al. Nonablative fractional photothermolysis for acne scars: clinical and in vivo microscopic documentation of treatment efficacy. Dermatologic therapy. 2012;25; 463-467
Yang Q, Huang W, Qian H, Chen S, Ma L, Lu Z. Efficacy and safety of 1550-nm fractional laser in the treatment of acne scars in Chinese patients: A split-face comparative study. Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology. 2016;18; 312-316
Todd J, Ud-Din S, Bayat A. Extensive self-harm scarring: successful treatment with simultaneous use of a single layer skin substitute and split-thickness skin graft. Eplasty. 2012;12; e23
Nouri K, Jimenez GP, Harrison-Balestra C, Elgart GW. 585-nm pulsed dye laser in the treatment of surgical scars starting on the suture removal day. Dermatol Surg. 2003;29; 65-73; discussion 73
Tierney E, Mahmoud BH, Srivastava D, Ozog D, Kouba DJ. Treatment of surgical scars with nonablative fractional laser versus pulsed dye laser: a randomized controlled trial. Dermatol Surg. 2009;35; 1172-1180
Anderson RR, Donelan MB, Hivnor C, Greeson E, Ross EV, Shumaker PR, et al. Laser treatment of traumatic scars with an emphasis on ablative fractional laser resurfacing: consensus report. JAMA dermatology. 2014;150; 187-193
Gold MH, Berman B, Clementoni MT, Gauglitz GG, Nahai F, Murcia C. Updated international clinical recommendations on scar management: part 1-evaluating the evidence. Dermatol Surg. 2014;40; 817-824
Gold MH, McGuire M, Mustoe TA, Pusic A, Sachdev M, Waibel J, et al. Updated international clinical recommendations on scar management: part 2-algorithms for scar prevention and treatment. Dermatol Surg. 2014;40; 825-831
Mustoe TA, Cooter RD, Gold MH, Hobbs FD, Ramelet AA, Shakespeare PG, et al. International clinical recommendations on scar management. Plastic and reconstructive surgery. 2002;110; 560-571
Choi JE, Oh GN, Kim JY, Seo SH, Ahn HH, Kye YC. Ablative fractional laser treatment for hypertrophic scars: comparison between Er:YAG and CO2 fractional lasers. J Dermatolog Treat. 2014;25; 299-303
Ozog DM, Liu A, Chaffins ML, Ormsby AH, Fincher EF, Chipps LK, et al. Evaluation of clinical results, histological architecture, and collagen expression following treatment of mature burn scars with a fractional carbon dioxide laser. JAMA dermatology. 2013;149; 50-57
Cervelli V, Gentile P, Spallone D, Nicoli F, Verardi S, Petrocelli M, et al. Ultrapulsed fractional CO2 laser for the treatment of post-traumatic and pathological scars. J Drugs Dermatol. 2010;9; 1328-1331
El-Zawahry BM, Sobhi RM, Bassiouny DA, Tabak SA. Ablative CO fractional resurfacing in treatment of thermal burn scars: an open-label controlled clinical and histopathological study. Journal of cosmetic dermatology. 2015
Ho D, Jagdeo J. Excellent Aesthetic and Functional Outcome After Fractionated Carbon Dioxide Laser Skin Graft Revision Surgery: Case Report and Review of Laser Skin Graft Revision Techniques. J Drugs Dermatol. 2015;14; 1285-1288
Hultman CS, Edkins RE, Wu C, Calvert CT, Cairns BA. Prospective, before-after cohort study to assess the efficacy of laser therapy on hypertrophic burn scars. Annals of plastic surgery. 2013;70; 521-526
Hultman CS, Friedstat JS, Edkins RE, Cairns BA, Meyer AA. Laser resurfacing and remodeling of hypertrophic burn scars: the results of a large, prospective, before-after cohort study, with long-term follow-up. Annals of surgery. 2014;260; 519-529; discussion 529-532
Khandelwal A, Yelvington M, Tang X, Brown S. Ablative fractional photothermolysis for the treatment of hypertrophic burn scars in adult and pediatric patients: a single surgeon’s experience. Journal of burn care & research : official publication of the American Burn Association. 2014;35; 455-463
Levi B, Ibrahim A, Mathews K, Wojcik B, Gomez J, Fagan S, et al. The Use of CO2 Fractional Photothermolysis for the Treatment of Burn Scars. Journal of burn care & research : official publication of the American Burn Association. 2016;37; 106-114
Sever C, Uygur F, Kulahci Y, Oksuz S, Sahin C, Yuksel F. Treatment of facial burn scars with CO2 laser resurfacing and thin skin grafting. The Journal of craniofacial surgery. 2010;21; 1024-1028
Suh D-H CK-Y, Song K-Y, et al. Revision of burn scars using ablative fractional CO<sub>2</sub> laser. Journal of the American Academy of Dermatology. 2012;66; AB216
van Drooge AM, Vrijman C, van der Veen W, Wolkerstorfer A. A randomized controlled pilot study on ablative fractional CO2 laser for consecutive patients presenting with various scar types. Dermatol Surg. 2015;41; 371-377
Poetschke J, Dornseifer U, Clementoni MT, Reinholz M, Schwaiger H, Steckmeier S, et al. Ultrapulsed fractional ablative carbon dioxide laser treatment of hypertrophic burn scars: evaluation of an in-patient controlled, standardized treatment approach. Lasers in medical science. 2017;32; 1031-1040
Alster TS, Williams CM. Treatment of keloid sternotomy scars with 585 nm flashlamp-pumped pulsed-dye laser. Lancet. 1995;345; 1198-1200
Paquet P, Hermanns JF, Pierard GE. Effect of the 585 nm flashlamp-pumped pulsed dye laser for the treatment of keloids. Dermatol Surg. 2001;27; 171-174
Wittenberg GP, Fabian BG, Bogomilsky JL, Schultz LR, Rudner EJ, Chaffins ML, et al. Prospective, single-blind, randomized, controlled study to assess the efficacy of the 585-nm flashlamp-pumped pulsed-dye laser and silicone gel sheeting in hypertrophic scar treatment. Archives of dermatology. 1999;135; 1049-1055
Durani P, Bayat A. Levels of evidence for the treatment of keloid disease. Journal of plastic, reconstructive & aesthetic surgery : JPRAS. 2008;61; 4-17
Allison KP, Kiernan MN, Waters RA, Clement RM. Pulsed dye laser treatment of burn scars. Alleviation or irritation? Burns : journal of the International Society for Burn Injuries. 2003;29; 207-213
Rossi A, Lu R, Frey MK, Kubota T, Smith LA, Perez M. The use of the 300 microsecond 1064 nm Nd:YAG laser in the treatment of keloids. J Drugs Dermatol. 2013;12; 1256-1262
Koike S, Akaishi S, Nagashima Y, Dohi T, Hyakusoku H, Ogawa R. Nd:YAG Laser Treatment for Keloids and Hypertrophic Scars: An Analysis of 102 Cases. Plast Reconstr Surg Glob Open. 2014;2; e272
Apfelberg DB, Maser MR, White DN, Lash H. Failure of carbon dioxide laser excision of keloids. Lasers Surg Med. 1989;9; 382-388
You HJ, Kim DW, Yoon ES, Park SH. Comparison of four different lasers for acne scars: Resurfacing and fractional lasers. Journal of plastic, reconstructive & aesthetic surgery : JPRAS. 2016;69; e87-95
Chapas AM, Brightman L, Sukal S, Hale E, Daniel D, Bernstein LJ, et al. Successful treatment of acneiform scarring with CO2 ablative fractional resurfacing. Lasers Surg Med. 2008;40; 381-386
Alexis AF, Coley MK, Nijhawan RI, Luke JD, Shah SK, Argobi YA, et al. Nonablative Fractional Laser Resurfacing for Acne Scarring in Patients With Fitzpatrick Skin Phototypes IV-VI. Dermatol Surg. 2016;42; 392-402
Naein FF, Soghrati M. Fractional CO2 laser as an effective modality in treatment of striae alba in skin types III and IV. Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences. 2012;17; 928-933
Shin JU, Roh MR, Rah DK, Ae NK, Suh H, Chung KY. The effect of succinylated atelocollagen and ablative fractional resurfacing laser on striae distensae. J Dermatolog Treat. 2011;22; 113-121
Yang YJ, Lee GY. Treatment of Striae Distensae with Nonablative Fractional Laser versus Ablative CO(2) Fractional Laser: A Randomized Controlled Trial. Annals of dermatology. 2011;23; 481-489
de Angelis F, Kolesnikova L, Renato F, Liguori G. Fractional nonablative 1540-nm laser treatment of striae distensae in Fitzpatrick skin types II to IV: clinical and histological results. Aesthetic surgery journal. 2011;31; 411-419
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2018 Springer-Verlag GmbH Deutschland, ein Teil von Springer Nature
About this chapter
Cite this chapter
Pötschke, J., Gauglitz, G. (2018). Laserbehandlungen von Narben. In: Kautz, G. (eds) Energie für die Haut. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-56436-3_25
Download citation
DOI: https://doi.org/10.1007/978-3-662-56436-3_25
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-662-56435-6
Online ISBN: 978-3-662-56436-3
eBook Packages: Medicine (German Language)