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Arteriovenöse Malformation des zentralen Nervensystems

  • Harun Badakhshi
Chapter
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Zusammenfassung

Arteriovenöse Malformationen (AVM) sind anormale angeborene Läsionen des Gefäßsystems, die ein Knäuel oder Geflecht (Nidus) im Gehirn bilden und durch das Fehlen von Kapillaren charakterisiert sind. Diese auch als Shunts bezeichnete Läsionen können ja nach Lokalisation und Größe Einfluss auf die Hirnfunktionen haben. Methode der Wahl ist die chirurgische Herangehensweise, wobei gut selektierte Patienten (w/m) von einer multimodalen Therapie profitieren könnten. Einige Fälle werden einer kontrollierten klinischen Observation unterzogen, um dem Risiko einer Hämorrhagie Rechnung zu tragen. Nicht-invasive bildgeführte stereotaktische Radiochirurgie zeigte sich als effiziente, kosteneffektive und sichere Methode sowohl bei jüngeren als auch älteren Patienten (w/m). Es konnte demonstriert werden, dass die stereotaktische Radiochirurgie Morbidität und Mortalität der AVM senken kann, dies gilt insbesondere für tiefer sitzenden AVM-Läsionen. Sie kann allein, aber auch mit einer endovaskulären Embolisation eingesetzt oder/und mit einer operativen Sanierung sequenziell kombiniert werden.

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Copyright information

© Springer-Verlag GmbH Deutschland 2017

Authors and Affiliations

  • Harun Badakhshi
    • 1
  1. 1.Direktor der Klinik für integrative RadioonkologieKlinikum Ernst von Bergmann, akademisches Krankenhaus der CharitéPotsdamDeutschland

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