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Indikation von CRS und HIPEC bei peritonealen Metastasen von Pankreaskarzinomen

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Peritoneale Tumoren und Metastasen

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Zusammenfassung

Peritoneale Metastasen eines duktalen Pankreaskarzinoms bedingen sowohl bei syn- als auch bei metachronem Auftreten eine sehr schlechte Prognose. Aufgrund der limitierten Überlebenszeit wird in Anbetracht der potenziellen perioperativen Morbidität grundsätzlich keine Indikation für eine zytoreduktive Chirurgie und hypertherme intraperitoneale Chemotherapie (HIPEC) gesehen. Da jedoch auch nach radikaler Resektion lokal fortgeschrittener Pankreastumore im Verlauf häufig Lokalrezidive und/oder peritoneale Metastasen auftreten, könnte sich vielleicht eine Indikation für eine «prophylaktische” HIPEC zur Vermeidung einer peritonealen Karzinose nach Resektion von Pankreaskarzinomen ergeben. Dies ist derzeit Gegenstand klinischer Studien.

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Authors and Affiliations

  1. Universitätsklinikum Tübingen, Klinik für Allgemeine, Viszeral- und Trans­plantationschirurgie, Hoppe-Seyler-Straße 3, 72076, Tübingen, Deutschland

    Prof. Dr. med. S. Beckert

  2. Universitätsklinikum Tübingen, Klinik für Allgemeine, Viszeral- und ­Transplantationschirurgie, Hoppe-Seyler-Straße 3, 72076, Tübingen, Deutschland

    Dr. med. Dr. med. univ. F. Struller, PD Dr. med. I. Königsrainer & Prof. Dr. med. A. Königsrainer

  3. Universitätsklinikum Tübingen, Klinik für Allgemeine, Viszeral- und ­Transplanta­tionschirurgie, Hoppe-Seyler-Straße 3, 72076, Tübingen, Deutschland

    Dr. med. Dr. med. univ. P. Horvath

Authors
  1. Prof. Dr. med. S. Beckert
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  2. Dr. med. Dr. med. univ. F. Struller
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  3. Dr. med. Dr. med. univ. P. Horvath
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  4. PD Dr. med. I. Königsrainer
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  5. Prof. Dr. med. A. Königsrainer
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Corresponding authors

Correspondence to S. Beckert , F. Struller , P. Horvath , I. Königsrainer or A. Königsrainer .

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Editors and Affiliations

  1. Charité Campus Virchow-Klinikum, Berlin, Deutschland

    Beate Rau

  2. Krankenhaus Barmherzige Brüder, Regensburg, Deutschland

    Pompiliu Piso

  3. Universitätsklinikum Tübingen, Tübingen, Deutschland

    Alfred Königsrainer

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Beckert, S., Struller, F., Horvath, P., Königsrainer, I., Königsrainer, A. (2018). Indikation von CRS und HIPEC bei peritonealen Metastasen von Pankreaskarzinomen. In: Rau, B., Piso, P., Königsrainer, A. (eds) Peritoneale Tumoren und Metastasen. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-54500-3_24

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  • DOI: https://doi.org/10.1007/978-3-662-54500-3_24

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-54499-0

  • Online ISBN: 978-3-662-54500-3

  • eBook Packages: Medicine (German Language)

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