Abstract
This chapter reviews the presentation, diagnosis, and treatment of hyperparathyroidism in children. Compared to adults, parathyroid disease is rare in children and this rarity may lead to delay in diagnosis of the parathyroid problem and delay in recognition of associated conditions. The common causes of hyperparathyroidism, such as parathyroid adenoma and hyperplasia, as well as the less common etiologies, such as adenocarcinoma are considered. Primary hyperparathyroidism (PHPT), which results from overproduction of parathyroid hormone (PTH), is the most common cause of HPT in both adults and children. Secondary and tertiary hyperparathyroidism are related to chronic renal failure, which results in continuous stimulation of PTH production, and are less common causes of HPT in children. Parathyroid adenocarcinoma is an exceedingly rare cause of HPT, accounting for less than 1% of all cases of HPT in adults and it is probably even more uncommon in children. Throughout this discussion of parathyroid disease in children, comparisons will be made to the more frequent adult disease, highlighting the similarities and differences between the two populations.
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Burke, J., Chen, H., Gosain, A. (2018). Parathyroid Surgery in Children. In: Ledbetter, D., Johnson, P. (eds) Endocrine Surgery in Children. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-54256-9_6
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