Abstract
Parathyroids glands play a key role in calcium homeostasis. This chapter reviews the embryology, anatomy and physiology of the parathyroid glands with special consideration of hyperparathyroidism and the development of the parathyroid gland and nearby structures as they relate to parathyroidectomy and the potential risks and complications of parathyroid surgery.
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Arnault V, Beaulieu A, Lifante J-C, Serra AS, Sebag F, Mathonnet M, Hamy A, Meurisse M, Carnaille B, Kraimps J-L. Multicenter study of 19 aortopulmonary window parathyroid tumors: the challenge of embryologic origin. World J Surg. 2010;34:2211–6.
Leroyer-Alizon E, David L, Anast CS, Dubois PM. Immunocytological evidence for parathyroid hormone in human fetal parathyroid glands. J Clin Endocrinol Metab. 1981;52:513–6.
Simmonds CS, Karsenty G, Karaplis AC, Kovacs CS. Parathyroid hormone regulates fetal-placental mineral homeostasis. J Bone Miner Res. 2010;25:594–605.
Grigorieva IV, Mirczuk S, Gaynor Ku, Nesbit MA, Grigorieva EF, Wei Q, Ali A, Fairclough RJ, Stacey JM, Stechman MJ, Mihai R, Kurek D, Fraser WD, Hough T, Condie BG, Manley N, Grosveld F, Thakker RV. Gata3-deficient mice develop parathyroid abnormalities due to dysregulation of the parathyroid-specific transcription factor Gcm2. J Clin Invest. 2010;120(6):2144–55.
Chisaka O, Capecchi MR. Regionally restricted developmental defects resulting from targeted disruption of the mouse homeobox gene hox-1.5. Nature. 1991;350(6318):473–9.
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Walls, G.V., Mihai, R. (2018). Parathyroid Gland Embryology, Anatomy and Physiology. In: Ledbetter, D., Johnson, P. (eds) Endocrine Surgery in Children. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-54256-9_5
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DOI: https://doi.org/10.1007/978-3-662-54256-9_5
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