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Bilayer Collagen Membrane in Articular Cartilage Defect Repair

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Bio-orthopaedics

Abstract

Although cartilage is a tissue with a relatively simple structure compared to other tissues of the body, its injury can be extremely symptomatic in time, with significant economic and social implications for the patients. The potential healing of articular cartilage is strongly limited, and this represents a problem in orthopedic surgery. In fact, the cartilage belongs to a very low quantity of cells and lacks totally of blood support by vessels, which—differently than in other tissues—lead all the recruited cells to activate a local repair. When a chondral lesion occurs, its possible evolution will result in osteoarthritis because its symptoms are not so strong at the beginning. This has an important impact in active population who present joints at high risk for trauma during their lifetime, limiting every personal activity and work. Therefore, it is essential to provide an effective treatment which should be comprehensive of all phases of injury, addressed to the repair of initial structural damage as well as the inflammatory and destructive processes which follow and result in osteoarthritis.

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Authors and Affiliations

  1. Orthopaedic Unit, University La Sapienza, Polo Pontino, ICOT, Latina, Italy

    Francesco Allegra, Enrico Bonacci, Gennaro Campopiano & Giovanni Corsini

Authors
  1. Francesco Allegra
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  2. Enrico Bonacci
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  3. Gennaro Campopiano
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  4. Giovanni Corsini
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Corresponding author

Correspondence to Francesco Allegra .

Editor information

Editors and Affiliations

  1. O.A.S.I. Bioresearch Foundation NPO, Milan, Italy

    Alberto Gobbi

  2. Clínica do Dragão, Espregueira-Mendes Sports Centre – FIFA Medical Centre of Excellence, Porto, Portugal

    JoĂŁo Espregueira-Mendes

  3. Musculoskeletal and Joint Research Foundation, San Diego, California, USA

    John G. Lane

  4. Department of Orthopedics, Acibadem University, Istanbul, Turkey

    Mustafa Karahan

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Allegra, F., Bonacci, E., Campopiano, G., Corsini, G. (2017). Bilayer Collagen Membrane in Articular Cartilage Defect Repair. In: Gobbi, A., Espregueira-Mendes, J., Lane, J., Karahan, M. (eds) Bio-orthopaedics. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-54181-4_42

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  • DOI: https://doi.org/10.1007/978-3-662-54181-4_42

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-54180-7

  • Online ISBN: 978-3-662-54181-4

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