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Building the Basis for Patient-Specific Meniscal Scaffolds

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Bio-orthopaedics

Abstract

The current strategies for the total or partial meniscus replacement with allograft transplantation or scaffold implantation need to be improved to overcome the limitations in the clinics. In addition to the required biological and biomechanical performance of the implants, the size and the shape of the implant are critical for the success of the treatment. The commercial implants are re-sized by cutting at the time of surgery according to the patient’s need; however, not completely in a 3D manner. The meniscal implants should advance beyond the traditional biomaterial concept by being patient-specific not only in terms of size and shape but regarding the cells and biologics derived from the patient. Herein, we overview the recent reports related to manufacturing of patient-specific meniscal implants.

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Acknowledgments

I. F. Cengiz thanks the Portuguese Foundation for Science and Technology (FCT) for the Ph.D. scholarship (SFRH/BD/99555/2014). J. M. Oliveira also thanks the FCT for the funds provided under the program Investigador FCT 2012 (IF/00423/2012).

Author information

Authors and Affiliations

  1. 3B’s Research Group—Biomaterials, Biodegradables and Biomimetics, Univ. Minho, European Institute of Excellence on Tissue Engineering and Regenerative Medicine, Avepark—Parque de Ciência e Tecnologia, Zona Industrial da Gandra, Guimarães, 4805-017, Barco, Portugal

    Ibrahim Fatih Cengiz, Hélder Pereira, João Espregueira-Mendes, Joaquim Miguel Oliveira & Rui Luís Reis

  2. ICVS/3B’s–PT Government Associate Laboratory, Braga, Portugal

    Ibrahim Fatih Cengiz, Hélder Pereira, João Espregueira-Mendes, Joaquim Miguel Oliveira & Rui Luís Reis

  3. Orthopedic Department, Centro Hospitalar Póvoa de Varzim, Vila do Conde, Portugal

    Hélder Pereira

  4. Computer Science Department, University of Crete, Voutes Campus, 70013, Heraklion, Greece

    Marios Pitikakis

  5. Clínica Espregueira-Mendes F.C. Porto Stadium—FIFA Medical Centre of Excellence, Porto, Portugal

    João Espregueira-Mendes

  6. Dom Henrique Research Centre, Porto, Portugal

    João Espregueira-Mendes

  7. Orthopedic Department, Minho University, Minho, Portugal

    João Espregueira-Mendes

Authors
  1. Ibrahim Fatih Cengiz
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  2. Hélder Pereira
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  3. Marios Pitikakis
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  4. João Espregueira-Mendes
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  5. Joaquim Miguel Oliveira
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  6. Rui Luís Reis
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Corresponding author

Correspondence to Ibrahim Fatih Cengiz .

Editor information

Editors and Affiliations

  1. O.A.S.I. Bioresearch Foundation NPO, Milan, Italy

    Alberto Gobbi

  2. Clínica do Dragão, Espregueira-Mendes Sports Centre – FIFA Medical Centre of Excellence, Porto, Portugal

    João Espregueira-Mendes

  3. Musculoskeletal and Joint Research Foundation, San Diego, California, USA

    John G. Lane

  4. Department of Orthopedics, Acibadem University, Istanbul, Turkey

    Mustafa Karahan

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Cengiz, I.F., Pereira, H., Pitikakis, M., Espregueira-Mendes, J., Oliveira, J.M., Reis, R.L. (2017). Building the Basis for Patient-Specific Meniscal Scaffolds. In: Gobbi, A., Espregueira-Mendes, J., Lane, J., Karahan, M. (eds) Bio-orthopaedics. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-54181-4_32

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  • DOI: https://doi.org/10.1007/978-3-662-54181-4_32

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-54180-7

  • Online ISBN: 978-3-662-54181-4

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