Zusammenfassung
Die Mammasonographie nahm ihren Anfang in der klinischen Anwendung zur Diagnose gutartiger und bösartiger Veränderungen der Brust in den 1970er-Jahren. Mit der fortschreitenden technischen Entwicklung zu hochauflösenden Schallsonden stellt die Mammasonographie heute ein sowohl komplementäres zu anderen bildgebenden Methoden ergänzendes, als auch ein eigenständiges diagnostisches Verfahren dar. Durch ihre den anatomischen Gegebenheiten nahen Darstellung des Drüsengewebes besitzt die Mammasonographie Vorteile in der diagnostischen Differenzierung gegenüber Methoden wie der Mammographie, die Überlagerungen der Bildebenen anwendet und die Diagnose mehr aus Sekundärphänomenen der Tumorentwicklung ableitet. Da der diagnostische Prozess »real time« abläuft, hängt die Leistungsfähigkeit der Mammasonographie – neben der technischen Ausrüstung – entscheidend von der Kompetenz des Untersuchers ab. Sind diese Voraussetzungen erfüllt, erreicht die Mammasonografie sowohl bei der symptomatischen Patientin (mit Tastbefund) als auch bei der asymptomatischen Patientin (Früherkennung) eine hohe diagnostische Treffsicherheit (Sensitivität). Zur definitiven (histologischen) Diagnosesicherung bedarf es der ultraschallgesteuerten Stanzbiopsie. Aufgefundene Herdbefunde werden nach dem ACR-BI-RADS-Atlas und nach den Kriterien der DEGUM nach Merkmalen beschrieben und einer Kategorie nach BI-RADS 1–5 entsprechend von benigne bis hochsuspekt zugeordnet.
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Literatur
American College of Radiology (ACR) (2003) ACR BI-RADS: Breast imaging reporting and data system. Breast imaging atlas. American College of Radiology, Reston, VA
American College of Radiology (ACR) (2014) ACR BI-RADS Atlas, 5th ed. Reston, VA, American College of Radiology
An YY, Kim SH, Kang, BJ (2014) Characteristic features and usefulness of MRI in breast cancer in patients under 40 years old: correlations with conventionel imaging and prognostic features. Breast Cancer 21: 302–315
Appleton DC, Hackney L, Narayanan S (2014) Ultrasonography alone for diagnosis of breast cancer in women under 40. Ann R Coll Surg Engl 96: 202–206
Azim HA Jr, Santoro L, Russell-Edu W, et al (2012) Prognosis of pregnancy-associated breast cancere: a metaanalysis of 30 studies. Breast Cancer 38: 843–842
Berg WA, Blume JD, Cormack JB, et al (2008) Combined screening with ultrasound and mammography vs. mammography alone in women at elevated risk of breast cancer. JAMA 299: 2151–2163
Berg WA, Cosgrove DO, Doré CJ, et al (2012) Shear-wave elastography improves the specificity of breast US: the BE1 multinational study of 939 masses. Radiology 262: 435–449
Berg WA, Bandos AI, Mendelson EB, et al (2016) Ultrasound as the primary screening test for breast cancer: analysis from ACRIN 6666. J Natl Cancer Inst 108. pii:djv367. doi: 10.1093/jnci/djv367
Brem F, Tabar L, Duffy WS, et al (2015) Assesing improvement of breast cancer with three.dimensionel automated breast US in women with dense breast tissue: The SomoInsight Study. Radiology 274: 663–673
Brem RF, Lenihan MJ, Liebermann J, Torrente J (2015) Screening breast ultrasound: past, present, and future. AJR 204: 234–240
Buchberger W, Niehoff A, Obrist P, et al (2000) Clinically and mammographically occult breast lesions: detection and classification with high resolution sonography. Semin Ultrasound CT MR 21: 325–336
Carlsen J, Ewertsen C, Sletting S, et al (2015) Ultrasound elastography in breast cancer diagnosis. Ultrasound Med 36 (6): 550–62
Chan SW, Cheung PS, Chan S, Lau SS, et al (2008) Benefit of ultrasonography in the detection of clinically and mammographically occult breast cancer. World J Surg 32: 2593–2598
Checka CM, Chun JE, Schnabel FR, Lee J, Toth H (2012) The relationship of mammographic density and age: implications for breast cancer screening. AJR 198: 292–295
Chen SC, Cheung YC, Lo YF, et al (2003) Sonographic differentiation of invasive and intraductal carcinomas of the breast. BJR 76: 600–604
Cho KR, Seo BK, Woo OH et al. (2016) Breast cancer detection in a screening population: comparison of digital mammography, computer-aided detection applied to digital mammography and breast ultrasound. J Breast Cancer 19: 316–323
Choi YJ, Seong MH, Choi SH, Kook SH, et al (2011) Ultrasound and clinicopathological characteristics of tripel receptor-negative breast cancers. J Breast Cancer 14 (2): 119–123
Choi WJ, Joo HC, Kim HH, Shin HJ et al.(2014) Comparison of automated breast volume scanning and hand-held ultrasound in the detection of breast cancer: an analysis of 5,566 patient evaluations. Asian Pac J Cancer Prev 15: 9101–9105
Corsetti V, Houssami N, Aurora F, et al (2008) Breast screening with ultrasound in women with mammography-negative dense breasts: Evidence on incremental cancer detection and false positives, and associated cost. Eur J Cancer 44: 539–544
Corsetti V, Houssami N, Ghirardi M, et al (2011) Evidence of the effect of adjunct ultrasound screening in women with mammography-negative dense breasts: interval breast cancers at one year follow-up. Eur J Cancer 47: 1021–1026
Cosgrove DO, Kedar RP, Bamber JC, et al (1993) Breast diseases: color Doppler US in differential diagnoses. Radiology 189: 99–104
Du HY, Lin BR, Huang DP (2015) Ultrasonographic findings of tripel-negative breast cancer. Int J Clin Exp Med 8: 10040–10043
Farrokh A, Wojinski S, Degenhardt F (2013) Evaluation of real-time tissue sono-elastograqphy in the assessment of 214 breast lesions: limitations of this method resulting from different histologic subtypes, tumor size and tumor localization. Ultrasound Med Biol. 39: 2264–2271
Fischer T, Grigoryew M, Bossenz S et al. (2012) Sonographische Mikrokalkdetection – Potenzial einer neuen Methode. Ultraschall Med 33 (4): 357–365
Foxcroft LM, Evans EB, Porter AJ (2004) The diagnosis of breast cancer in women younger than 40. Breast 13: 297–306
Giger ML, Inciardi MF. Edwards A, Papaioannou J, Drukker K, Jiang Y, Brem R, Brown JB (2016) Automated breast ultrasound in breast cancer screening of women with dense breasts: reader study of mammography-negative and mammography-positive cancers. AJR 206: 1341–1350
Girardi V, Tonegutti M, Ciatto S, et al (2013) Breast ultrasound in 22,131 asymptomatic women with negative mammography. Breast 22: 806–809
Hackelöer BJ, Lauth G, Duda V, et al (1980) Neue Möglichkeiten der Ultraschallmammographie. Geburtshilfe Frauenheilkd 40: 301–312
Hackelöer BJ, Duda V, Lauth G (1986) Ultraschall-Mammographie. Springer, Heidelberg
Hille H (2011) Advances in breast ultrasound. In: Thoirs K (Hrsg) Sonography. www.intechopen.com, p 73–92
Hille H, Vetter M, Hackelöer BJ (2007) Die Eignung der hochfrequenten Sonographie zur Diagnostik des DCIS. Ultraschall Med 28: 307–312
Hille H, Vetter M, Hackelöer BJ (2012) The accuracy of BI-RADS classification of breast ultrasound as a first-line imaging method. Ultraschall Med 33 (2): 160–163
Houssami N, Turner RM (2016) Rapid review: Estimates of incremental breast cancer detection from tomosynthesis (3D-mammography) screening in women with dense breasts. Breast 30: 141–145
Houssami N, Irwig L, Simpson JM, McKessar M, Blome S, Noakes J (2003) Sydney breast imaging accuracy study: comparative sensitivity and specificity of mammography and sonography in young women with symptoms. AJR 180: 935–940
Hwang JY, Han BK, Ko EY et al. (2016) Screening ultrasound in women with negative mammograqphy: outcome analysis. Yonsei Med 56: 1352–1358
Jellins J, Kossof G, Buddee FW, Reeve TS (1971) Ultrasonic visualization of the breast. Med Journ of Australia 1: 305–307
Johnson K, Sarma D, Hwang ES (2015) Lobular breast cancer series: imaging. Breast Cancer Res 17: 94
Jørgensen KJ (2012) Is the tide turning against breast screening? Breast Cancer Res 14: 107
Kelly KM, Richwald GA (2011) Automated whole-breast ultrasound: advancing the performance of breast cancer screening. Semin Ultrasound CT MR 32: 273–280
Kim SJ, Moon WK, Cho N, et al (2011) The detection of recurrent breast cancer in patients with a history of breast cancer surgery: comparison of clinical breast examination, mammography and ultrasonography. Acta Radiol 52: 15–20
Kobayashi T (1974) Clinical evaluation of ultrasound techniques in breast tumors and malignant abdominal tumors. Excerpta Medica 191–198
Kolb T, Lichy J, Jeffrey H (2002) Comparison of the performance of screening mammography, physical examination, and breast ultrasound and evaluation of factors that influence them: An analysis of 27.825 patient evaluations. Radiology 225: 165–175
Krainick-Strobel U, Hahn M, Duda VF, et al (2005) Arbeitsgemeinschaft Minimalinvasive Mammainterventionen (AG MiMi) der Deutschen Gesellschaft für Senologie: Onkologie. Konsensusempfehlung zu Anwendung und Indikationen der Vakuumbiopsie der Brust unter Ultraschallsicht. Geburtsh Frauenheilk 65: 526–529
Kuhl CK, Strobel K, Bieling H et al. (2017) Supplemental breast MR Imaging screening of women with average risk of breast cancer. Radiology 283: 361–370
Leclere B, Molinie F, Tretarre B, Stracci F, Daubisse-Marliac L, Colonna M; GRELL Working Group (2013) Trends in incidence of breast cancer among women under 40 in seven European countries: a GRELL cooperative study. Cancer Epidemiol 37: 544–549
Lee YY, Roberts CL, Dobbins T, Stavrou E, Black K, Morris J, Young J (2012) Incidence and outcomes of pregnancy-associated cancer in Australia: a population-based linkage study. BJOG 119: 1572–1582
Lee SH, Chang JM, Cho N et al. (2014) Practice guideline fort the performance of breast ultrasound elastography. Ultrasonography 33: 3–10
Lenz S (2011) Breast ultrasound in office gynecology – Ten years of experience. Ultraschall in Med 32: 3S
Li B, Zhao X, Dai SC, Cheng W (2014) Associations between mammography and ultrasound imaging features and molecular characteristics of triple negative breast cancer. Asian Pac J Cancer Prev 15: 3555–3559
Liu B, Zheng Y, Huang G et al. (2016) Breast lesions: Quantitative diagnosis using ultrasound shear wave elastography – a systematic review and meta-analysis. Ultrasound Med Biol 42: 835–847
Madjar H, Ohlinger R, Mundinger A, et al (2006) BI-RADS analoge DEGUM Kriterien von Ultraschallbefunden der Brust – Konsens des Arbeitskreises Mammasonographie der DEGUM. Ultraschall Med 27: 374–379
Madjar H, Becker S, Doubek K, et al (2010) Bedeutung der Mammasonographie für die Brustkrebsfrüherkennung in der gynäkologischen Praxis. Ultraschall Med 31: 289–229
Merlo DF, Ceppi M, Filiberti R, Bocchini V, Znaor A, Gamulin M, Primic-Zakeli M, Bruzzi P, Bouchardy C, Fucic A, AIRTUM WG (2012) Breast cancer incidence trends in European women aged 20-39 years at diagnosis. Breast Cancer Res Treat 134: 363–370
Moon WK, Im JG, Koh YH, et al (2000) US of mammographically detected clustered microcalcifications. Radiology 217: 849–854
Moon HJ, Jung I, Park J, et al (2015) Comparison of cancer yields and diagnostic performance of screening mammography vs. supplemental screening ultrasound in 4394 women with average risk for breast cancer. Ultraschall Med 36: 255–263
Mu WJ, Zhong WJ, Yao JY et al. (2016) Ultrasonic elastography research based on a multicenter study: Adding strain ratio after 5-point scoring evaluation or not. PLoS One 11: e0148330
Myers ER, Moorman P, Gierisch JM, et al (2015) Benefits and harms of breast cancer screening, a systematic review. JAMA 314: 1615–1634
Neumann JL (2014) Brustkrebs des Mannes. Frauenarzt 55: 582–586
Ohuchi N, Suzuki A, Masaaki K, et al (2016) Sensitivity and specifity of mammography and adjunctive ultrasonography to screen for breast cancer in the Japan Strategic Anti-cancer Randomized Trial (J-Start): a randomised controlled trial. Lancet 387: 341–348
Oliveira TMG, Elias Jr JE, Melo AF, Teixeira SR, Salomao CF, Goncalves LM, Fria FM, Tiezzi DG, Andrade JM, Muglia V (2014) Evolving concepts in breast lobular neoplasia and invasive lobular carcinoma, and their impact on imaging methods. Insights Imaging 5: 183–194
Pisano ED, Yaffe MJ (2014) Breast cancer screening. Should tommosynthesis replace digital mammography? JAMA 311: 2488–2489
Raza S, Goldkamp AL, Chikarmane SA, et al (2010) US of breast masses categorized as BI-RADS 3, 4, and 5: pictorial review of factors influencing clinical management. RadioGraphics 30: 1199–1213
Scheel JR, Lee JM, Spraque BL, et al (2015) Screening ultrasound as an adjunct to mammography in women with mammographically dense breasts. A J Obstet Gynecol 212: 9–17
Schmachtenberg C, Fischer T, Hamm B, Bick U (2017) Diagnostic performance of automated breast volume scanning (ABVS) compared to handheld ultrasonography with breast MRI as the gold standard. Acad Radiol 24: 954–961
Schmadeka R, Harmon BE, Singh M (2014) Triple-negative breast carcinoma: current and emerging concepts. Am J Clin Pathol 141: 462–477
Schulz KD, Albert US (Hrsg) (2008) Brustkrebsfrüherkennung, S3-Leitlinie. Zuckschwerdt, München
Shin HJ, Kim HH, Kim SM, et al (2008) Screening-detected and symptomatic ductal carcinoma in situ: Differences in the sonographic and pathologic features. AJR 190: 516–525
Shin HJ, Kim HH, Joo HC (2015) Current status of automated breast ultrasonography. Ultrasonography 34: 165–172
Shen S, Zhou Y, Xu Y et al (2015) A multi-centre randomised trial comparing ultrasound vs mammography for screening breast cancer in high-risk Chinese women. BJC 112: 998–1004
Sigrist RMs, Liau J, Kaffas AE, Chammas MC, Willmann JK. (2017) Ultrasound elastograpy: review of techniques and clinical applications. Theranostics 7: 1303–1329
Skaane P (2017) Breast cancer screening with digital breast tomosynthesis. Breast Cancer 24: 32–41
Sohn YM, Kim MJ, Kim EK (2013) Impact of preoperative bilateral whole breast sonography in patients with invasive lobular carcinoma: results from two medical centers. Ultraschall Med 34: 359–367
Stähler E, Kübler U (2015) Mammakarzinom: Früherkennung aus tumorbiologischer Sicht. Frauenarzt 56: 320–325
Stavros AT (2004) Breast ultrasound. Lippincott Williams, Philadelphia, p 448
Tan KP, Azlan MZ, Choo MY, et al (2014) The comparative accuracy of ultrasound and mammography in the detection of breast cancer. Med J Malaysia 69: 79–85
Wang ZL, Li Y, Wan WB et aL(2017) Shear-wave-elastography: could it be helpful for the diagnosis of non-mass-like breast lesions? Ultrasound Med Biol 43: 83–90
Watermann OD, Temper C, Hefler LA, et al (2004) Ultrasound morphology of invasive lobular breast cancer is different compared with other types of breast cancer. Utrasound Med Biol 31: 176–174
Wilczek B, Wilczek HE, Rasoulivan L, Leifland K (2016) Adding 3D automated breast ultrasound to mammography screening in women with heterogeneously and extremely dense breasts: report from a hospital-based, high-volume, single-center breast cancer screening program. Eur J Radiol 85: 1554–1563
Wild JJ, Reid JM (1952) Further pilot echographic studies on the histological structure of tumors of the human breast. Am J Pathol 28: 839–861
Wojcinski S, Solimann AA, Schmidt J, Makowski L, Degenhardt F (2012) Sonographic features of tripel-negative and non-tripel-negative breast cancer. J Ultrasound Med 31: 1531–1541
Wojcinski S, Boehme E, Farrokh A, et al (2013a) Ultrasound real-time elastography can predict malignancy in BI-RADS-US 3 lesions. BMC Med Imaging 13: 159
Wojcinski S, Gyapong S, Farrokh A, Soergel P, et al (2013b) Diagnostic performance and inter-observer concordance in lesion detection with the automated breast volume scanner (AVBS). BMC Med Imaging 13: 36
Yang WT, Tse GMK (2004) Sonographic, mammographic, and histopathologic correlation of symptomatic ductal carcinoma in situ. AJR 182: 101–110
Yang Q, Liu HY, Liu D, Song YQ (2015) Ultrasonographic features of tripel-negative breast cancer: a comparison with other breast cancer subtypes. Asian Pac J Cancer Prev 16: 3229–3232
Ying X, Lin Y, Xia X, Hu B, Zhu Z, He P (2012) A comparison of mammography and ultrasound in women with breast disease: a receiver operating characteristic analysis. Breast J 18(2): 130–138
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Hackelöer, BJ., Hille, HH. (2018). Mammasonographie. In: Gembruch, U., Hecher, K., Steiner, H. (eds) Ultraschalldiagnostik in Geburtshilfe und Gynäkologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-53662-9_36
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DOI: https://doi.org/10.1007/978-3-662-53662-9_36
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