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Neurochirurgische Schmerztherapie pp 173–228Cite as

Chirurgische Therapie von Gesichtsschmerzen

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Zusammenfassung

Die Voraussetzung für eine erfolgreiche medikamentöse oder chirurgische Therapie von Kopf- und Gesichtsschmerzen ist die korrekte Diagnosestellung bei Kenntnis von Differenzialdiagnosen oder Mischformen. Ganz entscheidend ist, dem leidenden Patienten nicht durch falsch indizierte oder falsch gewählte chirurgische Eingriffe noch mehr Schmerzen zuzufügen. Jedem Neurochirurgen sind diejenigen Patienten zu Genüge bekannt, bei denen ganze Serien von Zähnen gezogen wurden, bevor eine Trigeminusneuralgie diagnostiziert wurde oder bei denen nach peripheren chirurgischen Verfahren mit konsekutiven neuropathischen Schmerzen durch zusätzliche neuroläsionelle Verfahren Phantomschmerzen im Gesicht, die sogenannte Anaesthesia dolorosa, erzeugt wurden.

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Literatur

  • Abdennebi B, Guenane L (2014) Technical considerations and outcome assessment in retrogasserian balloon compression for treatment of trigeminal neuralgia. Series of 901 patients. Surg Neurol Int 5: 118

    Article  PubMed  PubMed Central  Google Scholar 

  • Adams CB (1989) Microvascular compression: an alternative view and hypothesis. J Neurosurg 70: 1–12

    Article  CAS  PubMed  Google Scholar 

  • Adson AW (1924) The surgical treatment of glossopharyngeal neuralgia. Arch Neurol Psychiat 12: 487–506

    Article  Google Scholar 

  • Albrecht K, Krump J (1954) Diagnose, Differentialdiagnose und Behandlungsmöglichkeiten der Trigeminusneuralgie (unter besonderer Berücksichtigung der konservativen Behandlung mit Hydantoinpräparaten und Vitamin B12) Münch Med Wschr 96: 985–987

    CAS  PubMed  Google Scholar 

  • Amir R, Devor M (1992) Axonal cross-excitation in nerve-end neuromas: comparison of A- and C-fibers. J Neurophysiol 68: 1160–1166

    Article  CAS  PubMed  Google Scholar 

  • André N (1756) Observations pratiques sur les maladies de l’urèthre et sur plusiers faits convulsifs, & la guérison de plusiers maladies chirurgicales, avec la décomposition d’un remède propre à réprimer la dissolution gangréneuse & cancéreuse, & à la réparer; avec des principes qui pourront servir à employer les différens caustiques. Delaguette, Paris

    Google Scholar 

  • Apfelbaum RI (1983) Surgery for tic doloureux. Clin Neurosurg 31: 351–368

    Article  CAS  PubMed  Google Scholar 

  • Areatäus, the Cappadokian (1896) Vol. 28 übersetzt von Francis Adams, Sydenham Society Publications , London

    Google Scholar 

  • Arias MJ (1986) Percutaneous retrogasserian glycerol rhizotomy for trigeminal neuralgia. J Neurosurg 65: 32–36

    Article  CAS  PubMed  Google Scholar 

  • Arias MJ (1986) Percutaneous radio-frequency thermocoagulation with low temperature in the treatment of essential glossopharyngeal neuralgia. Surg Neurol 25: 94–96

    Article  CAS  PubMed  Google Scholar 

  • Aubuchon AC, Chan MD, Lovato JF, Balamucki CJ, Ellis TL, Tatter SB, McMullen KP, Munley MT, Deguzman AF, Ekstrand KE, Bourland JD, Shaw EG (2011) Repeat gamma knife radiosurgery for trigeminal neuralgia. Int J Radiat Oncol Biol Phys 81: 1059–1065

    Article  PubMed  Google Scholar 

  • Baker GS, Kerr FWL (1963) Structural changes in the trigeminal system following compresion procedures. J Neurosurg 20: 181–184

    Article  CAS  PubMed  Google Scholar 

  • Barker FG 2nd, Jannetta PJ, Bissonette DJ, Larkins MV, Jho HD (1996) The long-term outcome of microvascular decompression for trigeminal neuralgia. N Engl J Med 334: 1077–1183

    Article  PubMed  Google Scholar 

  • Bartholow R (1876) A Practical Treatise and Materia Medica and Therapeutics. D. Appleton, London

    Google Scholar 

  • Bauer KH (1932) Elektrokoagulation des Ganglion Gasseri. Zbl Chir 819: 2963

    Google Scholar 

  • Beaver DL (1967) Electron microscopy of the gasserian ganglion in trigeminal neuralgia. J Neurosurg 26: Suppl: 138–150

    Article  Google Scholar 

  • Beck DW, Olson JJ, Urig EJ (1986) Percutaneous retrogasserian glycerol rhizotomy for treatment of trigeminal neuralgia. J Neurosurg 65: 28–31

    Article  CAS  PubMed  Google Scholar 

  • Bederson JB, Wilson CB (1989) Evaluation of microvascular decompression and partial sensory rhizotomy in 252 cases of trigeminal neuralgia. J Neurosurg 71: 359–367

    Article  CAS  PubMed  Google Scholar 

  • Belber CJ, Rak RA (1987) Balloon compression rhizolysis in the surgical management of trigeminal neuralgia. Neurosurgery 20: 908–913

    Article  CAS  PubMed  Google Scholar 

  • Bell C (1821) On the nerves: giving an account on some experiments on their structure and functions, which lead to a new arrangement of the system. Philos Trans R Soc Lond 111: 398–424

    Article  Google Scholar 

  • Bell C (1829) On the nerves of the face: second part. Philos Trans R Soc Lond 119: 317–330

    Article  Google Scholar 

  • Benoliel R, Biron A, Quek SY, Nahlieli O, Eliav E (2006) Trigeminal neurosensory changes following acute and chronic paranasal sinusitis. Quintessence Int 37: 437–443

    PubMed  Google Scholar 

  • Bergenheim AT, Linderoth B (2008) Diplopia after balloon compression of retrogasserian ganglion rootlets for trigeminal neuralgia: Technical case report. Neurosurgery 62: 533–534

    Article  Google Scholar 

  • Bergouignan (1942) Cures heureuses de névralgies faciales essentielles par le diphenyl-hydantoine de soude. Rev Laryngol Otol Rhinol 63: 34–41

    Google Scholar 

  • Bernstein JG (1828) Bibliothek oder Verzeichniss der medicinisch-chirurgischen Schriften, ingleichen der in sämtlichen Zeitschriften des In-und Auslandes befindlichen Abhandlungen, Beobachtungen und Erfahrungen von 1750 bis mit Einschluss 1828, Frankfurt Andräische Buchhandlung, S. 411 und 412

    Google Scholar 

  • Bertling F (1953) Die Novocain-Neuraltherapie des Ganglion stellatum als Behandlungsmethode auf dem Gebiet der Hals-, Nasen-, Ohrenkrankheiten. Indikationen und Erfahrungen. Z Laryngol Rhinol Otol 32: 76–87

    CAS  PubMed  Google Scholar 

  • Beydoun A, Schmidt D, D´Souza J (2002) Oxcarbazepine versus carbamazepine in trigeminal neuralgia: a meta-analysis of three double blind comparative trials. Neurology 58 (Suppl 3): 02.083

    Google Scholar 

  • Bowsher D, Miles JB, Haggett CE, Eldridge PR (1997) Trigeminal neuralgia: a quantitative sensory perception threshold study in patients who had not undergone previous invasive procedures. J Neurosurg 86: 190–192

    Article  CAS  PubMed  Google Scholar 

  • Blom S (1962) Trigeminal neuralgia: its treatment with a new anticonvulsant drug (G-32883). Lancet 1: 839–840

    Article  CAS  PubMed  Google Scholar 

  • Borsook H, Kremers MY, Wiggins CG (1940) The relief of symptoms of major trigeminal neuralgia(tic doloureux) following the use of vitamin B1 and concentrated liver extract. JAMA 114: 1421–1423

    Google Scholar 

  • Bremerich A, Tronnier V, Miltner F (1988) Die isolierte oder kombinierte Chemoneurolyse in der Schmerztherapie inoperabler Karzinome im Mund-, Kiefer-, Gesichtsbereich. Dtsch Z Mund-, Kiefer- u Gesichtschir 12: 315–317

    CAS  Google Scholar 

  • Bretschneider H (1847) Versuch einer Begründung der Pathologie und Therapie äusserer Neuralgien, Verlag Friedrich Maucke, Jena

    Google Scholar 

  • Brisman R (2000) Gamma knife radiosurgery for primary management for trigeminal neuralgia. J Neurosurg 93 Suppl 3: 159–161

    PubMed  Google Scholar 

  • Brisman R (2004) Gamma knife surgery with a dose of 75 to 76.8 Gray for trigeminal neuralgia. J Neurosurg 100: 848–854

    Article  PubMed  Google Scholar 

  • Broggi G (1975) Thermorhizotomy in trigeminal neuralgia; preliminary report of 46 cases. Adv Neurosurg 3: 274–286

    Article  Google Scholar 

  • Broggi G, Servello D, Franzini A, Giorgi C (1987) Electrical stimulation of the Gasserian Ganglion for facial pain: preliminary results. Acta neurochir Suppl 39: 144–146

    Article  CAS  PubMed  Google Scholar 

  • Broggi G, Franzini A, Lasio G, Giorgi C, Servello D (1990) Long-term results of percutaneous retrogasserian thermorhizotomy for „essential“ trigeminal neuralgia: considerations in 1000 consecutive patients. Neurosurgery 26: 783–786

    Article  CAS  PubMed  Google Scholar 

  • Broggi G, Ferroli P, Franzini A, Servello D, Dones I (2000) Microvascular decompression for trigeminal neuralgia: comments on a series of 250 cases, including 10 patients with multiple sclerosis. J Neurol Neurosurg Psychiatry 68: 59–64

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Brown JA (1997) Direct carotid cavernous fistula after trigeminal balloon microcompression gangliolysis: Case report. Neurosurgery 40: 886

    Article  CAS  PubMed  Google Scholar 

  • Brown JA (2009) Percutaneous balloon compression for trigeminal neuralgia. Clin Neurosurg 56: 73–78

    PubMed  Google Scholar 

  • Brown J, Coursaget C, Preul M, Sangvai D (1999) Mercury water and cauterizing stones: Nicolas André and tic doloureux. J Neurosurg 90: 977–981

    Article  CAS  PubMed  Google Scholar 

  • Brown JA, Hoeflinger B, Long PB, Gunning WT, Rhoades R, Bennet-Clarke CA, et al (1996) Axon and ganglion cell injury in rabbits after percutaneous trigeminal balloon compression. Neurosurgery 38: 993–1004

    Article  CAS  PubMed  Google Scholar 

  • Brown JA, Pilitsis JG (2005) Percutaneous ballon compression for the treatment of trigeminal neuralgia: results in 56 patients based on ballon compressure monitoring. Neurosurg Focus 18: E10

    Article  PubMed  Google Scholar 

  • Brown JA, Pilitsis JG (2005) Motor cortex stimulation for central and neuropathic facial pain: a prospective study of 10 patients and observations of enhanced sensory and motor function during stimulation. Neurosurgery 56: 290–297

    Article  PubMed  Google Scholar 

  • Brown JA, Preul MC (1989) Percutaneous trigeminal ganglion compression for trigeminal neuralgia. J Neurosurg 70: 900–904

    Article  CAS  PubMed  Google Scholar 

  • Brown JA, Preul MC (1988) Trigeminal depressor response during percutaneous microcompression of the trigeminal ganglion for trigeminal neuralgia. Neurosurgery 23: 745–748

    Article  CAS  PubMed  Google Scholar 

  • v. Bruns V (1859) Therapeutische Würdigung der Neurotomie. Handb Prakt Chir, Abt.II, Bd. 1, 1859, S. 838

    Google Scholar 

  • Burchiel KJ (1988) Percutaneous retrogasserian glycerol rhizolysis in the management of trigeminal neuralgia. J Neurosurg 69; 361–366

    Article  CAS  PubMed  Google Scholar 

  • Burchiel KJ (1993) Trigeminal neuropathic pain. Acta Neurochir Suppl 58: 145–149

    CAS  PubMed  Google Scholar 

  • Burchiel KJ, Slavin KV (2000) On the natural history of trigeminal neuralgia. Neurosurgery 46: 152–154

    Article  CAS  PubMed  Google Scholar 

  • Campbell FG, Graham JG, Zikha KJ (1966) Clinical trial of carbamazepine (tegretol) in trigeminal neuralgia. J Neurol Neurosurg Psychiat 29: 265–267

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Canavero S, Bonicalzi V, Ferroli P, Zeme S, Montalenti E, Benna P (1995) Lamotrigine control of idiopathic trigeminal neuralgia. J Neurol Neurosurg Psychiatry 59: 646

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Cappabianca P, Spaziante R, Graziussi G, Taglialatela G, Peca C, De Divitiis E (1995) Percutaneous retrogasserian glycerol rhizolysis for treatment of trigeminal neuralgia. Technique and results in 191 patients. J Neurosurg Sci 39: 37–45

    CAS  PubMed  Google Scholar 

  • Carnochan JM (1858) Exsection of the trunk of the second branch of the fifth pair of nerves, beyond the ganglion of Meckel, for severe neuralgia of the face; with three cases. Am J med Sci 35. 134–143

    Article  Google Scholar 

  • Carrasso RL, Yehuda S, Streifler M (1979) Clomipraminer and amitriptyline in the treatment of severe pain. Int J Neurosci 9: 191–194

    Article  Google Scholar 

  • Carrazana EJ, Schachter SC (1998) Alternative uses of lamotrigine and gabapentin in the treatment of trigeminal neuralgia. Neurology 50: 1192

    Article  CAS  PubMed  Google Scholar 

  • Catruban, C (1938) Über die operative Therapie des Tic doloureux. Vortrag vor der Gesellschaft der Ärzte in Wien. In: Fischer I. Geschichte der Gesellschaft der Ärzte in Wien 1837–1937, Spinger Verlag, Wien

    Google Scholar 

  • Celsus AC (1971) De Medicina (Englische Übersetzung: Spencer WG). Cambridge, Harvard University Press

    Google Scholar 

  • Cenzato M, Stefini R, Ambrosi C, Latronico N, Milani D (2010) Surgical resolution of trigeminal neuralgia due to intra-axial compression by pontine cavernous angioma. World Neurosurg 74: 544–546

    Article  PubMed  Google Scholar 

  • Chakravorty BG (1965) Visual disturbance following fifth nerve ganglion injection. Report of two cases. J Neurosurg 23: 354–356

    Article  CAS  PubMed  Google Scholar 

  • Chang JW, Chang JH, Park YG, Chung SS (2000) Gamma knife radiosurgery for idiopathic and secondary trigeminal neuralgia. J Neurosurg 93 Suppl 3: 147–151

    PubMed  Google Scholar 

  • Chen JF, Tu PH, Lee ST (2011) Long-term follow-up of patients treated with percutaneous balloon compression for trigeminal neuralgia in Taiwan. World Neurosurg 76: 586–591

    Article  PubMed  Google Scholar 

  • Chen L, Xu M, Zou Y (2010) Treatment of trigeminal neuralgia with percutaneous glycerol injection into Meckel´s cavity: Experience with 4012 patients. Cell Biochem Biophys 58: 85–89

    Article  CAS  PubMed  Google Scholar 

  • Cheshire WP Jr (2002) Defining the role for gabapentin in the treatment of trigeminal neuralgia: a retrospective study. J Pain 3: 137–142

    Article  PubMed  Google Scholar 

  • Chroni E, Constantoyannis C, Prasoulis I, Kargiotis O, Kagadis GC, Georgiopoulos M, et al (2011) Masseter muscle function after percutaneous balloon compression of trigeminal ganglion for the treatment of trigeminal neuralgia: A neurophysiological follow-up study. Clin Neurophysiol 122: 410–413

    Article  PubMed  Google Scholar 

  • Conforti R, Parlato RS, De Paulis D, Cirillo M, Marrone V, Cirillo S, Moraci A, Parlato C (2012) Trigeminal neuralgia and persistent trigeminal artery. Neurol Sci 33: 1455–1458

    Article  PubMed  PubMed Central  Google Scholar 

  • Court JE, Kase CS (1976) Treatment of tic doloureux with a new anticonvulsant (clonazepam). J Neurol Neurosurg Psychiatry 39: 297–299

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Chang JW, Chang JH, Park YG, Chung SS (2000) Microvascular decompression in trigeminal neuralgia: a correlation of three-dimensional time-of-flight magnetic resonance angiography and surgical findings. Stereotact Funct Neurosurg 74: 167–174

    Article  CAS  PubMed  Google Scholar 

  • Christensen JC (1957) Percutaneous gangliolysis of the Gasserian ganglion with normal saline as treatment for trigeminal neuralgia. Acta Neurol Latinoam 3: 378–380

    Google Scholar 

  • Collet FJ (1916) Sur un nouveau syndrome paralytique pharyngo-laryngé par blessures du guerre (hemiplegia glosso-laryngo-scapulo-pharyngée). Lyon médical 124: 121–129

    Google Scholar 

  • Crooks DA, Miles JB (1996) Trigeminal neuralgia due to vascular compression in multiple sclerosis--post-mortem findings. Br J Neurosurg 10: 85–88

    Article  CAS  PubMed  Google Scholar 

  • Cruccu G, Leandri M, Feliciani M, Manfredi M (1990) Idiopathic and symptomatic trigeminal pain. J Neurol Neurosurg Psychiatry 53: 1034–1042

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Cruccu G, Leandri M, Iannetti GD, Mascia A, Romaniello A, Truini A, Galeotti F, Manfredi M (2001) Small-fiber dysfunction in trigeminal neuralgia: carbamazepine effect on laser-evoked potentials. Neurology 56: 1722–1726

    Article  CAS  PubMed  Google Scholar 

  • Cruccu G, Gronseth G, Alksne J, Argoff C, Brainin M, Burchiel K, Nurmikko T, Zakrzewska JM; American Academy of Neurology Society; European Federation of Neurological Society (2008) AAN-EFNS guidelines on trigeminal neuralgia management. Eur J Neurol 15: 1013–1028

    Article  CAS  PubMed  Google Scholar 

  • Cushing H (1900) A method of total extirpation of the Gasserian ganglion for trigeminal neuralgia. By a route through the temporal fossa and beneath the middle meningeal artery. J Amer Med Assoc 34: 1035–1041

    Google Scholar 

  • Dandy WE (1925) Section of the sensory root of the trigeminal nerve at the pons: preliminary report of the procedure. Bull John Hopkins Hosp 36: 105–106

    Google Scholar 

  • Dandy WE (1929) An operation for the cure of tic doloureux. Partial section of the sensory root at the pons. Arch Surg 18: 687–734

    Article  Google Scholar 

  • Dandy WE (1934) Concerning the cause of trigeminal neuralgia. Am J Surg 24: 447–455

    Article  Google Scholar 

  • Dandy WE (1963) The Brain, in Walters W, Ellis FHJ (eds): Lewis-Walters´ Practice of Surgery, Hagerstown. MD: WF Prior, Vol XII, S. 1–671

    Google Scholar 

  • Davidoff LM (1944) The relief of tic doloureux with large doses of ferrous carbonate. Trans Am Neurol Ass 70: 176

    CAS  Google Scholar 

  • Davidoff LM (1950) Trifacial neuralgia Oral Surg Oral Med Oral Pathol 3: 1239–1246

    Article  CAS  PubMed  Google Scholar 

  • Devor M, Amir R, Rappaport ZH (2002) Pathophysiology of trigeminal neuralgia: the ignition hypothesis. Clin J Pain 18: 4–13

    Google Scholar 

  • Dewhurst K (1957) A symposium on trigeminal neuralgia with contributions from Locke, Sydenham, and other eminent seventeenth century physicians. J. Hist Med Allied Sci 12: 21–36

    Article  CAS  Google Scholar 

  • Dieffenbach JF (1845) Operative Chirurgie. Bd 1, S.856

    Google Scholar 

  • Dogliotti AM (1938) First surgical sections in man of the lemniscus lateralis (Pain-Temperature pathway) at the brainstem for treatment of diffused rebellious pain. Anesth Analg 17: 143–145

    Article  Google Scholar 

  • Dollinger J (1912) Die Behandlung der Trigeminusneuralgie mit den Schlösser´schen Alkoholeinspritzungen. Dtsch Med. Wochenschr 7: 38

    Google Scholar 

  • Doyle DB (1923) A study of 4 cases of glossopharyngeal neuralgia. Arch Neurol Psychiat 9: 34–46

    Article  Google Scholar 

  • Du Y-F, Gu Q, Yang D-B, Dong X-Q, Du Q, Hao Wang H, Yu W-H (2015) Percutaneous balloon compression for primary trigeminal neuralgia in patients older than 80 years. Chin Neurosurg J 1:8. https://doi.org/10.1186/s41016-015-0007-2

    Article  Google Scholar 

  • Dumot C, Sindou M (2015) Trigeminal neuralgia due to neurovascular conflicts from venous origin: an anatomical-surgical study (consecutive series of 124 operated cases). Acta Neurochir 157: 455–466

    Article  PubMed  Google Scholar 

  • Dunteman E (2002) Peripheral nerve stimulation for unremitting ophthalmic postherpetic neuralgia. Neuromodulation 5: 32–37

    Article  PubMed  Google Scholar 

  • Ebel H, Rust D, Tronnier V, Böker D, Kunze S (1996) Chronic precentral stimulation in trigeminal neuropathic pain. Acta Neurochir 138: 1300–1306

    Article  CAS  PubMed  Google Scholar 

  • Ecker A (1974) Tic doloureux. Eight years after alcoholic Gasserian injection. N Y State Med J 74: 1586–1592

    CAS  Google Scholar 

  • Egan RA, Pless M, Shults WT (2001) Monocular blindness as a complication of trigeminal radiofrequency rhizotomy. Am J Ophtalmol 131: 237–240

    Article  CAS  Google Scholar 

  • Esfahani DR, Pisansky MT, Dafer RM, Anderson DE (2011) Motor cortex stimulation: functional magnetic resonance imaging-localized treatment for three sources of intractable facial pain. J Neurosurg 114: 189–195

    Article  PubMed  Google Scholar 

  • Ertl E (1942) Die peripherische Silberklammerungzur Behandlung der Trigeminusneuralgie. Mschr Ohrhk 76: 1

    Google Scholar 

  • Eulenburg A (1884) Die Osmiumsäurebehandlung bei peripheren Neuralgien. Berl klin Wochenschr 7: 99

    Google Scholar 

  • Farago F (1987) Trigeminal neuralgia: its treatment with two new carbamazepine analogues. Eur Neurol. 26: 73–83

    Article  CAS  PubMed  Google Scholar 

  • Fehr JM Schmidt E (1671) Naturae genius, medicorum Celsus, Jason Argonautarum, Bauschius occubuit. Misc. Cur. med.-phys. Acad. nat. cur., Jenae, 2 Jena

    Google Scholar 

  • Feletti A, Santi GZ, Sammartino F, Bevilacqua M, Cisotto P, Longatti P (2013) Peripheral trigeminal nerve field stimulation: report of 6 cases. Neurosurg Focus 35: E10

    Article  PubMed  Google Scholar 

  • Ferner H (1948) Zur Anatomie der intrakranialen Abschnitte des N. trigeminus. Arztl Wochensch. 3: 380

    CAS  PubMed  Google Scholar 

  • Ferner, H (1970) The anatomy of the trigeminal root and the Gasserian Ganglion and their relations to the cerebral meninges. In: Trigeminal Neuralgia (Walker A, Hassler W (eds). Thieme-Verlag S. 1–6

    Google Scholar 

  • Ferroli P, Fioravanti A, Schiariti M, Tringali G, Franzini A, Calbucci F, Broggi G (2009) Microvascular decompression for glossopharyngeal neuralgia: a long-term retrospectic review of the Milan-Bologna experience in 31 consecutive cases. Acta Neurochir 151: 1245–1250

    Article  PubMed  Google Scholar 

  • Fields WS, Hoff HE (1952) Relief of pain in trigeminal neuralgia by crystalline vitamin B12. Neurology 2: 131–139

    Article  CAS  PubMed  Google Scholar 

  • Flesch J (1909) Die Behandlung der Neuralgien mittels der Schlösser´schen Alkoholinjektion. Zentralbl Grenzgeb Med u. Chir 12: 15 und 16

    Google Scholar 

  • Flor H, Rasche D, Islamian AP, Rolko C, Yilmaz P, Ruppolt M, Capelle HH, Tronnier V, Krauss JK (2016) Subtle Sensory Abnormalities Detected by Quantitative Sensory Testing in Patients with Trigeminal Neuralgia. Pain Physician 19: 507–518

    PubMed  Google Scholar 

  • Fothergill S (1804) A concise and systematic account of a painful affection of the nerves of the face commonly called tic doloureux. London, John Murray

    Google Scholar 

  • Fraioli B, Esposito V, Guidetti B, Cruccu G, Manfredi M (1989) Treatment of trigeminal neuralgia by thermocoagulation, glycerolization, and percutaneous compression of the gasserian ganglion and/or retrogasserian rootlets: long-term results and therapeutic protocol. Neurosurgery 24: 239–245

    Article  CAS  PubMed  Google Scholar 

  • Frank F, Fabrizi AP (1989) Percutaneous surgical treatment of trigeminal neuralgia. Acta Neurochir 97: 128–130

    Article  CAS  PubMed  Google Scholar 

  • Frazier CH (1925) Subtotal resection of sensory root for relief of major trigeminal neuralgia. Arch Neurol Psychiat 13: 378–384

    Article  Google Scholar 

  • Frazier CH (1928) Operation for the radical cure of trigeminal neuralgia: analysis of five hundred cases. Ann Surg 88 : 534–547

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Freeman W, Watts JW (1946) Pain of organic disease relieved by prefrontal lobotomy. Lancet 1(6409): 953–955

    Article  CAS  PubMed  Google Scholar 

  • Freye E (1999) Opioide in der Medizin. Kapitel 26 Ganglionäre lokale Opioidanalgesie (GLOA), Springer Verlag Heidelberg, S. 189–191

    Google Scholar 

  • Fromm GH, Chattha AS, Terrence CF, Glass JD (1981) Role of inhibitory mechanisms in trigeminal neuralgia. Neurology 31: 683–687

    Article  CAS  PubMed  Google Scholar 

  • Fromm GH, Terrence CF, Maroon JC (1984) Trigeminal neuralgia. Current concepts regarding etiology and pathogenesis. Arch Neurol 41: 1204–1207

    Article  CAS  PubMed  Google Scholar 

  • Fromm GH Terrence CF, Chatta AF (1984) Baclofen in the treatment of trigeminal neuralgia: double-blind study and long-term follow-up. Ann Neurol 15: 240–244

    Article  CAS  PubMed  Google Scholar 

  • Fujimaki T, Hoya K, Sasaki T, Kirino T (1996) Recurrent trigeminal neuralgia caused by an inserted prosthesis: report of two cases. Acta Neurochir 138: 1307–1309

    Article  CAS  PubMed  Google Scholar 

  • Fujimaki T, Fukushima T, Miyazaki S (1990) Percutaneous retrogasserian glycerol injection in the management of trigeminal neuralgia. J Neurosurg 73. 212–216

    Article  CAS  PubMed  Google Scholar 

  • Fukuda H, Ishikawa M, Okumura R (2003) Demonstration of neurovascular compression in trigeminal neuralgia and hemifacial spasm with magnetic resonance imaging: comparison with surgical findings in 60 consecutive cases. Surg Neurol 59: 93–99

    Article  PubMed  Google Scholar 

  • Gardner WJ (1966) Cross talk--the paradoxical transmission of a nerve impulse. Arch Neurol 14: 149–156

    Article  CAS  PubMed  Google Scholar 

  • Gardner WJ, Miklos MV (1959) Response of trigeminal neuralgia to decompression of sensory root; discussion of cause of trigeminal neuralgia. J Am Med Assoc 170: 1773–1776

    Article  CAS  PubMed  Google Scholar 

  • Giorgi C, Broggi G (1984) Surgical treatment of glossopharyngeal neuralgia and pain from cancer of the nasopharynx. A 20-year experience. J Neurosurg 61: 952–955

    Article  CAS  PubMed  Google Scholar 

  • Glaser MA (1931) Treatment of trigeminal neuralgia with trichloroethylene. JAMA 96: 916–920

    Article  Google Scholar 

  • Goepel H (1949) Die Elektrokoagulation des Ganglion Gasseri nach Kirschner. Die Ergebnisse der Chirurgie und Orthopädie /Sonderabdruck aus Band 35, Springer, Berlin

    Google Scholar 

  • Graf CJ (1963) Trigeminal compression for tic doloureux. An evaluation. J Neurosurg 20: 1029–1032

    Article  CAS  PubMed  Google Scholar 

  • Green AL, Owen SL, Davies P, Moir L, Aziz TZ (2006) Deep brain stimulation for neuropathic cephalalgia.Cephalalgia 26: 561–567

    Article  CAS  PubMed  Google Scholar 

  • Gronseth G, Cruccu G, Alksne J, Argoff C, Brainin M, Burchiel K, Nurmikko T, Zakrzewska JM (2008) Practice parameter: the diagnostic evaluation and treatment of trigeminal neuralgia (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology and the European Federation of Neurological Societies. Neurology 71: 1183–1190

    Article  CAS  PubMed  Google Scholar 

  • Gudmundsson K, Rhoton AL Jr, Rushton JG (1971) Detailed anatomy of the intracranial portion of the trigeminal nerve. J Neurosurg 35: 592–600

    Article  CAS  PubMed  Google Scholar 

  • Gülicher D, Gerlach KL (2000) Inzidenz,Risikofaktoren und Verlauf von Sensibilitätsstörungen nach operativen Weisheitszahnentfernungen. Mund Kiefer Gesichtschir 4: 99–104

    Article  PubMed  Google Scholar 

  • Guiot G, Forjaz S (1947) La tractotomie mesencephalique par voie soustemporale. Rev. Neurol 79: 733–739

    Google Scholar 

  • Guo Z, Wu B, Du C, Cheng M, Tian Y (2016) Stereotactic Approach Combined with 3D CT Reconstruction for Difficult-to-Access Foramen Ovale on Radiofrequency Thermocoagulation of the Gasserian Ganglion for Trigeminal Neuralgia. Pain Med. 2016 Feb 13. pii: pnv108. [Epub ahead of print]

    Google Scholar 

  • Gustin SM, Peck CC, Wilcox SL, Nash PG, Murray GM, Henderson LA (2011) Different pain, different brain: thalamic anatomy in neuropathic and non-neuropathic chronic pain syndromes. J Neurosci 31: 5956–5964

    Article  CAS  PubMed  Google Scholar 

  • Haddad FS, Taha JM (1990) An unusual cause for trigeminal neuralgia: contralateral meningioma of the posterior fossa. Neurosurgery 26: 1033–1038

    Article  CAS  PubMed  Google Scholar 

  • Härtel F (1912) Intrakranielle Leitungsanästhesie des Ganglion Gasseri. Zentralbl f Chir 21

    Google Scholar 

  • Härtel F (1912) Behandlung schwerer Trigeminusneuralgien durch Alkoholinjektionen in das Ganglion Gasseri. Berlin Gesellsch f Chir 25. November Verhandlungen, S.15

    Google Scholar 

  • Härtel F (1913) Die Behandlung der Trigeminusneuralgie mit intrakraniellen Alkoholeinspritzungen. Habilitationsschrift. Verlag von Vogel, Leipzig

    Google Scholar 

  • Härtel F (1914) Über die intrakranielle Injektionsbehandlung der Trigeminusneuralgie. Med Klin 10: 582–584

    Google Scholar 

  • Härtel F (1935) Röntgenologische Darstellung des Foramen ovale des Schädels und ihre Bedeutung für die Behandlung der Trigeminusneuralgie. Dtsch med Wochenschr 61(27): 1069–1072

    Article  Google Scholar 

  • Härtel F (1938) 25 Jahre Ganglion-Injektionsbehandlung der Trigeminusneuralgie. Zschr ärztl. Fortb. 35: 303

    Google Scholar 

  • Haighton J (1798) A case of tic doloureux or painful affection of the face, successfully treated by division of the affected nerve. Medical Records London, S.19

    Google Scholar 

  • Hakanson S (1981) Trigeminal neuralgia treated by injection of glycerol into the trigeminal cistern. Neurosurgery 9: 638–649

    Article  CAS  PubMed  Google Scholar 

  • Hamer J (1986) Glossopharyngeusneuralgie und neurovaskuläre Dekompression. Nervenarzt 57: 302–305

    CAS  PubMed  Google Scholar 

  • Harris W (1912) Alcohol injection of the Gasserian Ganglion for trigeminal neuralgia. Lancet 1: 218–221

    Article  Google Scholar 

  • Harris W (1940) An analysis of 1443 cases of paroxysmal trigeminal neuralgia (trigeminal tic) and the end-results of Gasserian alcohol injection. Brain 63: 209–240

    Article  Google Scholar 

  • Hartley F (1892) Intracranial neurectomy of the second and third division of the fifth nerve; a new method. NY Med J 55: 317–319

    Google Scholar 

  • Helis CA, Lucas JT Jr, Bourland JD, Chan MD, Tatter SB, Laxton AW (2015) Repeat Radiosurgery for Trigeminal Neuralgia. Neurosurgery 77: 755–761

    Article  PubMed  Google Scholar 

  • Henderson WR (1965) The anatomy of the Gasserian ganglion and the distribution of pain in relation to injections and operations for trigeminal neuralgia. Ann R Coll Surg Engl 37: 346

    CAS  PubMed  PubMed Central  Google Scholar 

  • Henson CF, Goldman HW, Rosenwasser RH, Downes MB, Bednarz G, Pequignot EC, Werner-Wasik M, Curran WJ, Andrews DW (2005) Glycerol rhizotomy versus gamma knife radiosurgery for the treatment of trigeminal neuralgia: an analysis of patients treated at one institution. Int J Radiat Oncol Biol Phys. 63: 82–90.-373

    Article  PubMed  Google Scholar 

  • Herweh C, Kress B, Rasche D, Tronnier V, Tröger J, Sartor K, Stippich C (2007) Loss of anisotropy in trigeminal neuralgia revealed by diffusion tensor imaging. Neurology 68: 776–778

    Article  CAS  PubMed  Google Scholar 

  • Hillenbrand HJ (1946) Zur Behandlung der Trigeminusneuralgie. Med Klin 41: 605–607

    CAS  PubMed  Google Scholar 

  • Hilton DA, Love S, Gradidge T, Coakham HB (1994) Pathological findings associated with trigeminal neuralgia caused by vascular compression. Neurosurgery 35: 299–303

    Article  CAS  PubMed  Google Scholar 

  • Hirschel G (1913) Lehrbuch der Lokalanästhesie für Studierende und Ärzte, Von Bergmann-Verlag, Wiesbaden

    Book  Google Scholar 

  • Horsley V (1891) Remarks on the Various Surgical Procedures Devised for the Relief or Cure of Trigeminal Neuralgia (Tic Douloureux). Brit Med J 2: 1139–1143, 1191–93, 1249–1252

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Hosobuchi Y, Adams JE, Rutkin B (1973) Chronic thalamic stimulation for the control of facial anesthesia dolorosa. Arch Neurol 29: 158–161

    Article  CAS  PubMed  Google Scholar 

  • Hübner B (1968) Ist die Elektrokoagulation des Ganglion Gasseri bei der Trigeminusneuralgie noch zeitgemäß? Langenbecks Arch Klin Chir 322; 577–581

    Google Scholar 

  • Hude C (1923) Aretaeus edidit Carolus Hude. Corpus medicorum Graecorum 2, Leipzig/Berlin

    Google Scholar 

  • Hutchinson B (1820) Cases of Tic doloureux successfully treated. Longman, Hurst, Rees, Orme and Brown; London

    Google Scholar 

  • Ilberg G (1923) Das neurologisch-psychiatrische Wissen und Können des Aretäus von Kappadokien. Z Gesamte Neurol Psychiatr 86

    Google Scholar 

  • Isik N, Pamir MN, Benli K, Erbengi A, Erbengi T, Ruacan S (2002) Experimental trigeminal glycerol injection in dogs: Histopathological evaluation by light and electron microscopy. Stereotact Funct Neurosurg 79: 94–106

    Article  CAS  PubMed  Google Scholar 

  • Ito M, Sonokawa T, Mishina H, Iizuka Y, Sato K (1996) Dural arteriovenous malformation manifesting as tic douloureux. Surg Neurol 45: 370–375

    Article  CAS  PubMed  Google Scholar 

  • Jääskeläinen SK (2004) The utility of clinical neurophysiological and quantitative sensory testing for trigeminal neuropathy. J Orofac Pain 18: 355–359

    PubMed  Google Scholar 

  • Jääskeläinen SK, Teerijoki-Oksa T, Virtanen A, Tenovuo O, Forssell H (2004) Sensory regeneration following intraoperatively verified trigeminal nerve injury. Neurology 62: 1951–1957

    Article  PubMed  Google Scholar 

  • Jääskeläinen SK, Teerijoki-Oksa T, Forssell H (2005) Neurophysiologic and quantitative sensory testing in the diagnosis of trigeminal neuropathy and neuropathic pain. Pain 117: 349–357

    Article  PubMed  Google Scholar 

  • Jackson J (1814) Extracts from a discourse on the disease called Tic doloureux. Med Phys Journal 31: 179–187

    Google Scholar 

  • Jakobs M, Unterberg A, Treede RD, Schuh-Hofer S, Ahmadi R (2016) Subcutaneous trigeminal nerve field stimulation for refractory trigeminal pain: a cohort analysis. Acta Neurochir 158: 1767–1774

    Article  PubMed  Google Scholar 

  • Jacoby GW (1885) The use of osmic acid in peripheral neuralgias. NY Med J 42: 123–126

    Google Scholar 

  • Jannetta PJ (1967) Arterial compression of the trigeminal nerve at the pons in patients with trigeminal neuralgia. J Neurosurg 26: Suppl: 159–162

    Article  Google Scholar 

  • Jannetta PJ (1976) Microsurgical approach to the trigeminal nerve for tic doloureux. Progr Neurol Surg 7: 180–200

    Google Scholar 

  • Jannetta PJ (1980) Neurovascular compression in cranial nerve and systemic disease. Ann Surg 192: 518–525

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Jannetta PJ, Rand RW (1966) Transtentorial retrogasserian rhizotomy in trigeminal neuralgia by microneurosurgical technique. Bull Los Angeles Neurol Soc 31: 93–99

    CAS  PubMed  Google Scholar 

  • Jawahar A, Kondziolka D, Kanal E, Bissonette DJ, Lunsford LD (2001) Imaging the trigeminal nerve and pons before and after surgical intervention for trigeminal neuralgia. Neurosurgery 48: 101–106

    CAS  PubMed  Google Scholar 

  • Jefferson A (1963) Trigeminal root and ganglion injections using phenol in glycerine for the relief of trigeminal neuralgia. J Neurol Neurosurg Psychiatr 26: 345–352

    Article  CAS  Google Scholar 

  • Jefferson A (1966) Trigeminal neuralgia: Trigeminal root and ganglion injections using phenol in glycerine. In: Pain (Knighton RS, Dumke PR Hrsg) Little, Brown, Boston S. 365–371

    Google Scholar 

  • Jelasic DF (1959) Über die Behandlung der Trigeminusneuralgie mittels mechanischer Kompression des Ganglion Gasseri durch das Foramen ovale. Acta neurochir 7: 440–445

    Article  CAS  PubMed  Google Scholar 

  • Jensen HP (1954) Die Behandlung der Trigeminusneuralgie mit Diphenylhydantoin. Ärztl Wochenschr 9: 105–108

    CAS  Google Scholar 

  • Jensen TS, Rasmussen P, Reske-Nielsen E (1982) Association of trigeminal neuralgia with multiple sclerosis: clinical and pathological features. Acta Neurol Scand 65: 182–189

    Article  CAS  PubMed  Google Scholar 

  • Johnson MD, Burchiel KJ (2004) Peripheral stimulation for treatment of trigeminal postherpetic neuralgia and trigeminal posttraumatic neuropathic pain: a pilot study. Neurosurgery 55: 135–141

    Article  PubMed  Google Scholar 

  • Jorns TP, Zakrewska JM (2007) Eivendence-based approach to the medical management of trigeminal neuralgia. Br J Neurosurg 21: 253–261

    Article  CAS  PubMed  Google Scholar 

  • Kandan SR, Khan S, Jeyaretna DS, Lhatoo S, Patel NK, Coakham HB (2010) Neuralgia of the glossopharyngeal and vagal nerves: long-term outcome following surgical treatment and literature review. Br J Neurosurgy 24: 441–446

    Article  Google Scholar 

  • Kanpolat Y, Savas A, Bekar A, Berk C (2001) Percutaneous controlled radiofrequency trigeminal rhizotomy for the treatment of idiopathic trigeminal neuralgia: 25-year experience with 1,600 patients. Neurosurgery 48: 524–532

    Article  CAS  PubMed  Google Scholar 

  • Kanpolat Y, Tatli M, Ugur HC, Kahilogullari G (2007) Evaluation of platybasia in patients with idiopathic trigeminal neuralgia. Surg Neurol 67: 78–81

    Article  PubMed  Google Scholar 

  • Katusic S, Beard CM, Bergstralh E, Kurland LT (1990) Incidence and clinical features of trigeminal neuralgia, Rochester, Minnesota, 1945–1984. Ann Neurol 27: 89–95

    Article  CAS  PubMed  Google Scholar 

  • Kerr FW, Miller RH (1966) The pathology of trigeminal neuralgia. Electron microscopic studies. Arch Neurol 15: 308–319

    Article  CAS  PubMed  Google Scholar 

  • King RB (1966) The value of mephenesin carbamate in the control of pain in patients with tic couloureux. J Neurosurg 25: 153–158

    Article  CAS  PubMed  Google Scholar 

  • King RB (1967) Evidence for a central etiology of tic douloureux. J Neurosurg 26: Suppl: 175–180

    Article  Google Scholar 

  • Kirschner M (1931) Zur Elektrochirurgie. Langenbecks Arch Klin Chir 167: 761–768

    Google Scholar 

  • Kirschner M (1932) Zur Elektrokoagulation des Ganglion Gasseri. Zentralbl Chir 47: 2841–2843

    Google Scholar 

  • Kirschner M (1942) Die Behandlung der Trigeminusneuralgie. Münchner Med Wschr 11: 235–269

    Google Scholar 

  • Kitson G (1806) Case of Tic doloureuse. In: The Edinburg Medical and Surgical Journal, 2nd vol. Archibald Constable and Company, Edinburgh 1806, S.319

    Google Scholar 

  • Klar E (1960) Über die Erfahrungen der Elektrokoagulation bei Trigeminusneuralgie an der Heidelberger Chirurgischen Universitätsklinik. Langenbecks Arch Klin Chir 294: 713–723

    Article  CAS  PubMed  Google Scholar 

  • Klein J, Sandi-Gahun S, Schackert G, Juratli TA (2016) Peripheral nerve field stimulation for trigeminal neuralgia, trigeminal neuropathic pain, and persistent idiopathic facial pain. Cephalalgia 36: 445–453

    Article  PubMed  Google Scholar 

  • Klun B (1992) Microvascular decompression and partial sensory rhizotomy in the treatment of trigeminal neuralgia: personal experience with 220 patients. Neurosurgery 30: 49–52

    Article  CAS  PubMed  Google Scholar 

  • Kolodziej MA, Hellwig D, Nimsky C, Benes L (2016) Treatment of Central Deafferentation and Trigeminal Neuropathic Pain by Motor Cortex Stimulation: Report of a Series of 20 Patients. J Neurol Surg A Cent Eur Neurosurg 77: 52–58

    PubMed  Google Scholar 

  • Könnecke W (1917) Amaurose nach Alkoholinjektion in das Ganglion Gasseri. Dtsch Zschr. Chir 140: 225–232

    Article  Google Scholar 

  • Kondo A (1997) Follow-up results of microvascular decompression in trigeminal neuralgia and hemifacial spasm. Neurosurgery 40: 46–51

    CAS  PubMed  Google Scholar 

  • Kondo A (1998) Follow-up results of using microvascular decompression for treatment of glossopharyngeal neuralgia. J Neurosurg 88: 221–225

    Article  CAS  PubMed  Google Scholar 

  • Kondziolka D, Lunsford LD, Flickinger JC, Young RF, Vermeulen S, Duma CM, Jacques DB, Rand RW, Regis J, Peragut JC, Manera L, Epstein MH, Lindquist C (1996) Stereotactic radiosurgery for trigeminal neuralgia: a multiinstitutional study using the gamma unit. J Neurosurg 84: 940–945

    Article  CAS  PubMed  Google Scholar 

  • Krafft TC, Hickel R (1994) Clinical investigation into the incidence of direct damage to the lingual nerve caused by local anaesthesia. J Craniomaxillofac Surg 22: 294–296

    Article  CAS  PubMed  Google Scholar 

  • Krasemann PH, Honkomp J (1968) Eine einfache Behandlung der Trigeminusneuralgie. Erfahrungsbericht über etwa 1000 periphere Elektrokoagulationen. Langenbeck Arch f Chir 32: 581–583

    Article  Google Scholar 

  • Krause F (1892) Resection des Trigeminus innerhalb der Schädelhöhle. Arch Klin Chir 44: 821–832

    Google Scholar 

  • Krause F (1896) Die Neuralgie des Trigeminus nebst der Anatomie und Physiologie des Nerven. F.C.W. Vogel, Leipzig

    Google Scholar 

  • Krönlein U (1892) Über eine neue Methode der Freilegung des dritten Astes des Nervus trigeminus (Retrobuccale Methode) Arch Klin Chir 43: 13–22

    Google Scholar 

  • Krol G, Arbit E (1988) Percutaneous electrocoagulation of the trigeminal nerve using CT guidance. Technical note. J Neurosurg 68: 972–973

    Article  CAS  PubMed  Google Scholar 

  • Kuhlenkampff D (1921) Über die Behandlung der Trigeminusneuralgie mit Alkoholinjektionen. Ergeb Orthop und Chir (Hrsg Payr E et al.) Springer Heidelberg, S. 356–452

    Google Scholar 

  • Kuhlenkampff D (1952) Über Pathogenese und Behandlung des Gesichts Tic. Deutsch Gesundheitswesen 32: 1022–1033

    Google Scholar 

  • Kustermans L, Van Buyten JP, Smet I, Coucke W, Politis C (2017) Stimulation of the Gasserian ganglion in the treatment of refractory trigeminal neuropathy. J Craniomaxillofac Surg 45: 39–46

    Article  PubMed  Google Scholar 

  • Lagares A, Rivas JJ, Jiménez L, Cicuendez M, Avendaño C (2010) Central demyelination in the pathogenesis of trigeminal neuralgia associated with cerebellopontine angle tumors: case report with ultrastructural trigeminal root analysis. Neurosurgery 66: E841–842

    Article  PubMed  Google Scholar 

  • Laitinen LV (1984) Trigeminus stereoguide: an instrument for stereotactic approach through the foramen ovale and foramen jugulare. Surg Neurol 22: 519–523

    Article  CAS  PubMed  Google Scholar 

  • Lanz-Wachsmuth (2004) Praktische Anatomie (Hrsg. J. Lang); Kopf-Gehirn-und Augenschädel, Sonderausgabe 2. Aufl, Springer Verlag Heidelberg, Berlin, New York

    Google Scholar 

  • Leal PR, Hermier M, Froment JC, Souza MA, Cristino-Filho G, Sindou M (2010) Preoperative demonstration of the neurovascular compression characteristics with special emphasis on the degree of compression, using high-resolution magnetic resonance imaging: a prospective study, with comparison to surgical findings, in 100 consecutive patients who underwent microvascular decompression for trigeminal neuralgia. Acta Neurochir 152: 817–825

    Article  PubMed  Google Scholar 

  • Leal PR, Hermier M, Souza MA, Cristino-Filho G, Froment JC, Sindou M (2011) Visualization of vascular compression of the trigeminal nerve with high-resolution 3T MRI: a prospective study comparing preoperative imaging analysis to surgical findings in 40 consecutive patients who underwent microvascular decompression for trigeminal neuralgia. Neurosurgery 69: 15–25

    Article  PubMed  Google Scholar 

  • Leandri M, Lundardi G, Inglese M, Messmer-Uccelli M, Mancardi GL, Gottlieb A, Solaro C (2000) Lamotrigine in trigeminal neuralgia secondary to multiple sclerosis. J Neurol 247: 556–558

    Article  CAS  PubMed  Google Scholar 

  • Lechin F, van der Dijn B, Lechin ME, Amat J, Lechin AE, Cabrera A, Gómez F, Acosta E, Arocha L, Villa S, Jiménez V (1989) Pimozide therapy for trigeminal neuralgia. Arch Neurol 46: 960–963

    Article  CAS  PubMed  Google Scholar 

  • Lee St, Chen JF (2003) Percutaneous trigeminal ganglion balloon compression for treatment of trigeminal neuralgia, part II: results related to compression duration. Surg Neurol 59: 149–154

    Article  Google Scholar 

  • Lefaucheur JP, Drouot X, Cunin P, Bruckert R, Lepetit H, Créange A, Wolkenstein P, Maison P, Keravel Y, Nguyen JP (2009) Motor cortex stimulation for the treatment of refractory peripheral neuropathic pain. Brain 132: 1463–1471

    Article  PubMed  Google Scholar 

  • Leksell L (1971) Sterotaxic radiosurgery in trigeminal neuralgia. Acta Chir Scand 137:311–314

    CAS  PubMed  Google Scholar 

  • Leksell L (1983) Stereotactic radiosurgery. J Neurol Neurosurg Psychiatry. 46797–803

    Google Scholar 

  • Lemos L, Alegria C, Oliveira J, Machado A, Oliveira P, Almeida A (2011) Pharmacological versus microvascular decompression approaches for the treatment of trigeminal neuralgia: clinical outcomes and direct costs. J Pain Res 4: 233–244

    CAS  PubMed  PubMed Central  Google Scholar 

  • Lemoyne J (1951) Le traitement de la névralgie faciale essentielle par le diphenyl-dithi-hydantoine. Concours Méd 73: 461–462

    CAS  PubMed  Google Scholar 

  • Lenchig S, Cohen J, Patin D (2012) A minimally invasive surgical technique for the treatment of posttraumatic trigeminal neuropathic pain with peripheral nerve stimulation. Pain Physician 15: E725–732

    PubMed  Google Scholar 

  • Letcher FS, Goldring S (1968) The effect of radiofrequency current and heat on peripheral nerve action potential in the cat. J Neurosurg 29: 42–47

    Article  CAS  PubMed  Google Scholar 

  • Lewy FH (1938) The first authentic case of major trigeminal neuralgia and some comments on the history of the disease. Ann Med Hist 10: 247–250

    Google Scholar 

  • Lichtor T, Mullan JF (1990) A 10-year follow-up review of percutaneous microcempression oft he trigeminal ganglion. J Neurosurg 72: 49–54

    Article  CAS  PubMed  Google Scholar 

  • Liebel JT, Menger N, Langohr H (2001) Oxcarbazepine in der Behandlung der Trigeminusneuralgie. Nervenheilkunde 20: 461–465

    Google Scholar 

  • Lieber R (1979) Komplikationen bei der Elektrokoagulation nach der Methode von Martin Kirschner; Inauguraldissertation der Univ. Düsseldorf

    Google Scholar 

  • Lin MH, Lee MH, Wang TC, Cheng YK, Su CH, Chang CM, Yang JT (2011) Foramen ovale cannulation guided by intra-operative computed tomography with integrated neuronavigation for the treatment of trigeminal neuralgia. Acta Neurochir 153: 1593–1599

    Article  PubMed  Google Scholar 

  • Lindemann A (1929) Gefahren und Fehlleistungen der Anästhesierung der Trigeminusbahnen. Dtsch Zahnheilk. 74

    Google Scholar 

  • Lindstrom P, Londblom V (1987) The analgesic effect of tocainide in trigeminal neuralgia. Pain 28: 45–50

    Article  CAS  PubMed  Google Scholar 

  • Linskey ME, Ratanatharathorn V, Peñagaricano J (2008) A prospective cohort study of microvascular decompression and Gamma Knife surgery in patients with trigeminal neuralgia. J Neurosurg 109 Suppl: 160–172

    PubMed  Google Scholar 

  • Lizars J (1961) Edinb Med Surg J 1821, vol 17, S. 529 nach Behrman S. John Lizars – Centenary for a forgotten pioneer of the surgery of trigeminal neuralgia Br Med J 2: 1665–666

    Google Scholar 

  • Lobato RD, Rivas JJ, Sarabia R, Lamas E (1990) Percutaneous microcompression of the gasserian ganglion. J Neurosurg 72: 546–553

    Article  CAS  PubMed  Google Scholar 

  • Löwenstein A (1922) Andere Lidoperationen. In: Elschnig A. Augenärztliche Operationslehre, Band 1, 2. und 3. Auflage, Springer Verlag Berlin, S. 376–409

    Google Scholar 

  • Love S, Coakham HB (2001) Trigeminal Neuralgia. Pathology and pathogenesis. Brain 124: 2347–2360

    CAS  PubMed  Google Scholar 

  • Love S, Gradidge T, Coakham HB (2001) Trigeminal neuralgia due to multiple sclerosis: ultrastructural findings in trigeminal rhizotomy specimens. Neuropathol Appl Neurobiol 27: 238–244

    Article  CAS  PubMed  Google Scholar 

  • Lücke GA (1874) Beschreibung der Neurektomie. Dtsch Zschr Chir 4: 322–329

    Article  Google Scholar 

  • Lunsford LD, Apfelbaum RI (1985) Choice of surgical therapeutic modalities for treatment of trigeminal neuralgia: microvascular decompression, percutaneous retrogasserian thermal, or glycerol rhizotomy. Clin Neurosurg 32: 319–333

    CAS  PubMed  Google Scholar 

  • Lunsford LD, Bennett MH (1984) Percutaneous retrogasserian glycerol rhizotomy for Tic doloureux: Part 1. Neurosurgery 14: 424–430

    Article  CAS  PubMed  Google Scholar 

  • Ma Y, Li YF, Wang QC, Wang B, Huang HAT (2016) Neurosurgical treatment of glossopharyngeal neuralgia: analysis of 103 cases. J Neurosurg 124: 1088–1092

    Article  PubMed  Google Scholar 

  • Marion DW, Jannetta PJ (1988) Use of perioperative steroids with microvascular decompression operations. Neurosurgery 22: 353–357

    Article  CAS  PubMed  Google Scholar 

  • Martínez-Álvarez R, Martínez-Moreno N, Kusak ME, Rey-Portolés G (2014) Glossopharyngeal neuralgia and radiosurgery. J Neurosurg 121 Suppl: 222–225

    PubMed  Google Scholar 

  • Massager N, Lorenzoni J, Devriendt D, Desmedt F, Brotchi J, Levivier M (2004) Gamma knife surgery for idiopathic trigeminal neuralgia performed using a far-anterior cisternal target and a high dose of radiation. J Neurosurg 100: 597–605

    Article  PubMed  Google Scholar 

  • Masuoka J, Matsushima T, Kawashima M, Nakahara Y, Funaki T, Mineta T (2011) Stitched sling retraction technique for microvascular decompression: procedures and techniques based on an anatomical viewpoint. Neurosurg Rev 34: 373–379

    Article  PubMed  Google Scholar 

  • Mathieu D, Effendi K, Blanchard J, Séguin M (2012) Comparative study of Gamma Knife surgery and percutaneous retrogasserian glycerol rhizotomy for trigeminal neuralgia in patients with multiple sclerosis. J Neurosurg 117 Suppl: 175–180

    PubMed  Google Scholar 

  • Matsushima T, Fukui M, Suzuki S, Rhoton AL Jr (1989) The microsurgical anatomy of the infratentorial lateral supracerebellar approach to the trigeminal nerve for tic douloureux. Neurosurgery 24: 890–895

    Article  CAS  PubMed  Google Scholar 

  • Menzel J, Piotrowski W, Penzholz H (1975) Long-term results of Gasserian ganglion electrocoagulation. J Neurosurg 42: 140–143

    Article  CAS  PubMed  Google Scholar 

  • McQuay H, Carroll D, Jadad AR, Wiffen P, Moore A (1995) Anticonvulsant drugs for neuropathic pain: a systematic review. BMJ 311: 1047–1052

    Google Scholar 

  • Meglio M (1984) Percutaneous implantable chronic electrode for radiofrequency stimulation oft he gasserian ganglion. A perspective in the management of trigeminal pain. Acta neurochir Suppl 33: 521–525

    Google Scholar 

  • Meglio M, Cioni B, d´Annunzio V (1987) Percutaneous microcompression of the gasserian ganglion. Acta neurochir 39 Suppl.; 142–143

    Google Scholar 

  • Mehrkens JH, Steude U (2007) Chronic electrostimulation of the trigeminal ganglion in trigeminal neuropathy: current state and future prospects. Acta Neurochir Suppl 97: 91–97

    Article  CAS  PubMed  Google Scholar 

  • Melis M, Lobo SL, Ceneviz C, Zawawi K, Al-Badawi E, Maloney G, Mehta N (2003) Atypical odontalgia: a review of the literature. Headache 43: 1060–1074

    Article  PubMed  Google Scholar 

  • Miller JP, Acar F, Bronwyn EH, Burchiel KJ (2009) Radiographic evaluation of trigeminal neurovascular compression in patients with and without trigeminal neuralgia. J Neurosurg 110: 627–632

    Article  PubMed  Google Scholar 

  • Møller AR (1991) The cranial nerve vascular compression syndrome: II. A review of pathophysiology. Acta Neurochir 113: 24–30

    Article  PubMed  Google Scholar 

  • Monsalve GA (2012) Motor cortex stimulation for facial chronic neuropathic pain: A review of the literature. Surg Neurol Int 3(Suppl 4): S290–311

    Article  PubMed  PubMed Central  Google Scholar 

  • Moulin DE (1998) Pain in central and peripheral demyelinating disorders. Neurol Clin 16: 889–898

    Article  CAS  PubMed  Google Scholar 

  • Müller H R, Levy A (1963) Zur Pathogenese der Trigeminusneuralgie. Acta Neurochir 11: 385–397

    Article  Google Scholar 

  • Mullan S, Lichtor T (1983) Percutaneous microcompression of the trigeminal ganglion for trigeminal neuralgia. J Neurosurg 59: 1007–1012

    Article  CAS  PubMed  Google Scholar 

  • Nagaseki Y, Horikoshi T, Omata T, Ueno T, Uchida M, Nukui H, Tsuji R, Sasaki H (1992) Oblique sagittal magnetic resonance imaging visualizing vascular compression of the trigeminal or facial nerve. J Neurosurg 77: 379–386

    Article  CAS  PubMed  Google Scholar 

  • Nanda A, Javalkar V, Zhang S, Ahmed O (2015) Long term efficacy and patient satisfaction of microvascular decompression and gamma knife radiosurgery for trigeminal neuralgia. J Clin Neurosci 22: 818–822

    Article  PubMed  Google Scholar 

  • Napier LE, Sen-Gupta PC (1942) A peculiar neurological sequel to administration of 4:4´-of diamidino-diphenyl-ethylene (M & B 744) Indian Med Gaz 77: 71–74

    Google Scholar 

  • Neuber G (1884) Über Osmiumsäureinjektionen bei peripheren Neuralgien. Med Chir Central Blatt 19: 230–232

    Google Scholar 

  • Nguyen JP, Keravel Y, Feve A, Uchiyama T, Cesaro P, Le Guerinel C, Pollin B (1997) Treatment of deafferentation pain by chronic stimulation of the motor cortex: report of a series of 20 cases. Acta Neurochir Suppl 68: 54–60

    CAS  PubMed  Google Scholar 

  • Nguyen JP, Velasco F, Brugières P, Velasco M, Keravel Y, Boleaga B, Brito F, Lefaucheur JP (2008) Treatment of chronic neuropathic pain by motor cortex stimulation: results of a bicentric controlled crossover trial. Brain Stimul 1: 89–96

    Article  PubMed  Google Scholar 

  • Nicol B, Regine WF, Courtney C, Meigooni A, Sanders M, Young B (2000) Gamma knife radiosurgery using 90 Gy for trigeminal neuralgia. J Neurosurg 93 Suppl 3: 152–154

    PubMed  Google Scholar 

  • North RB, Kidd DH, Piantadosi S, Carson BS (1990) Percutaneous retrogasserian glycerol rhizotomy. J Neurosurg 72: 851–856

    Article  CAS  PubMed  Google Scholar 

  • Nugent GR, Berry B (1974) Trigeminal neuralgia treated by with percutaneous radiofrequency lesions. J Neurosurg 40: 517–523

    Article  CAS  PubMed  Google Scholar 

  • Nugent GR (1982) Technique and results of 800 percutaneous radiofrequency thermocoagulations for trigeminal neuralgia. Appl Neurophysiol 45: 504–507

    CAS  PubMed  Google Scholar 

  • Nurmikko TJ, Eldridge PR (2001) Trigeminal neuralgia--pathophysiology, diagnosis and current treatment. Br J Anaesth 87: 117–132

    Article  CAS  PubMed  Google Scholar 

  • Obermann M, Yoon MS, Ese D, Maschke M, Kaube H, Diener HC, Katsarava Z (2007) Impaired trigeminal nociceptive processing in patients with trigeminal neuralgia. Neurology 69: 835–841

    Article  CAS  PubMed  Google Scholar 

  • Obermann M, Yoon MS, Sensen K, Maschke M, Diener HC, Katsarava Z (2008) Efficacy of pregabalin in the treatment of trigeminal neuralgia. Cephalalgia 28: 174–181

    Article  CAS  PubMed  Google Scholar 

  • Offerhaus HK (1910) Die Technik der Injektionen in die Trigeminusstämme und in das Ganglion Gasseri. Arch klin Chir 92: 74

    Google Scholar 

  • Olesen J (2013) for the Headache Classification Committee of the International Headache Society (IHS). The International Classification of Headache Disorders, 3rd edition (beta version). Cephalalgia; 33: 629–808

    Article  Google Scholar 

  • Onofrio BM (1975) Radiofrequency percutaneous Gasserian ganglion lesions. Results in 140 patients with trigeminal pain. J Neurosurg 42: 132–139

    Article  CAS  PubMed  Google Scholar 

  • Ori C, Salar G, Giron GP (1985) Cardiovascular and cerebral complications during glossopharyngeal nerve thermocoagulation. Anaesthesia 40: 433–437

    Article  CAS  PubMed  Google Scholar 

  • Green AL, Owen SL, Davies P, Moir L, Aziz TZ (2006) Deep brain stimulation for neuropathic cephalalgia. Cephalalgia 26: 561–567

    Article  CAS  PubMed  Google Scholar 

  • Pamir MN, Peker S (2006) Microvascular decompression for trigeminal neuralgia: a long-term follow-up study. Minim Invasive Neurosurg 49: 342–346

    Article  CAS  PubMed  Google Scholar 

  • Pancoast J (1872) New operation for the relief of persistent facial neuralgia. Philadelphia Medical Times 2: 85–87

    Google Scholar 

  • Panning B, Wiegand H (1985) Anästhesiologische Probleme und Komplikationen bei der Thermokoagulation des Ganglion Gasseri. Neurochirurgia 28: 61–63

    CAS  PubMed  Google Scholar 

  • Paravicini L (1858) Proposta di un nuovo metodo per la nevrotomia e l'escisione del ramo dentale inferiore prima del suo ingresso nella mascella. Annali universali di medicine 164: 44–50

    Google Scholar 

  • Parikh RR, Goodman RR, Rhome R, Sudentas E, Trichter F, Harrison LB, Choi W (2016) Linear accelerator-based flattening-filter-free stereotactic radiosurgery for trigeminal neuralgia: Feasibility and patient-reported outcomes. Pract Radiat Oncol 6: e1–7

    Article  PubMed  Google Scholar 

  • Park SC, Kwon do H, Lee do H, Lee JK (2016) Repeat Gamma-Knife radiosurgery for refractory or recurrent trigeminal neuralgia with consideration about the optimal second dose. World Neurosurg 86: 371–383

    Article  PubMed  Google Scholar 

  • Park S-S, Lee M-K, Kim J-W, Jung J-Y, Kim I-S, Ghang C-G (2008) Percutaneous balloon compression of trigeminal ganglion for the treatment of idiopathic trigeminal neuralgia: Experience in 50 Patients. J Korean Neurosurg Soc 43: 186–189

    Article  PubMed  PubMed Central  Google Scholar 

  • Pearce JMS (2013) The Neurology of Aretaeus: Radix Pedis Neurologia. Eur Neurol 70: 106–112

    Article  CAS  PubMed  Google Scholar 

  • Peker S, Kurtkaya O, Uzün I, Pamir MN (2006) Microanatomy of the central myelin-peripheral myelin transition zone of the trigeminal nerve. Neurosurgery 59: 354–359

    Article  PubMed  Google Scholar 

  • Pelletier VA, Poulos DA, Lende RA (1974) Functional localization in the trigeminal root. J Neurosurg 40: 504–513

    Article  CAS  PubMed  Google Scholar 

  • Penman J (1953) Some developments in the technique of trigeminal injection. Lancet 1: 760–764

    Article  CAS  PubMed  Google Scholar 

  • Penman J (1968) Trigeminal neuralgia. In: Vinken PJ, Bruyn GW (Hrsg) Handbook of Clinical Neurology, vol. 5, Headaches and cranial neuralgias. Amsterdam North-Holland, S. 296–322

    Google Scholar 

  • Penzholz H (1983) Die operative Behandlung der Trigeminusneuralgie. Akt Neurol 10: 29–34

    Article  Google Scholar 

  • Piazza M, Lee JY (2016) Endoscopic and Microscopic Microvascular Decompression. Neurosurg Clin N Am 27: 305–313

    Article  PubMed  Google Scholar 

  • Pichler H (1920) 51 Alkoholeinspritzungen in das Gassersche Ganglion. Wiener klin Wschr 21: 365–369

    Google Scholar 

  • Piotrowski W (1968) Derzeitiger Standpunkt zur Elektrokoagulation des Ganglion Gasseri beim Gesichtsschmerz. Langenbecks Arch klin Chir 322: 573–577

    Article  CAS  Google Scholar 

  • Pitres JA, Verger TPH (1902) Nevralgie faciale traitée par les injections modificatrices d` alcool. Soc de Méd et de Chir de Bordeaux

    Google Scholar 

  • Plessner W (1916) Über Trigeminuserkrankung infolge von Trichloräthylenvergiftung. Berl Klin Wochenschr 53: 25–26

    Google Scholar 

  • Plessner W (1916) Vorläufige Mitteilung über Behandlungsversuche der Trigeminusneuralgie mit Trichloräthylen. Berl Klin Wochenschr 53: 514–515

    Google Scholar 

  • Poirier J (1903) Résection du ganglion supérieur pour tic doloureux de la face. Soc de Chirurg Juillet 1903, Arch Gén de Méd 1790

    Google Scholar 

  • Pollock BE, Boes CJ (2011) Stereotactic radiosurgery for glossopharyngeal neuralgia: preliminary report of 5 cases. J Neurosurg 115: 936–939

    Article  PubMed  Google Scholar 

  • Pollock BE, Phuong LK, Foote RL, Stafford SL, Gorman DA (2001) High-dose trigeminal neuralgia radiosurgery associated with increased risk of trigeminal nerve dysfunction. Neurosurgery 49: 58–62

    CAS  PubMed  Google Scholar 

  • Pollock BE, Phuong LK, Gorman DA, Foote RL, Stafford SL (2002) Stereotactic radiosurgery for idiopathic trigeminal neuralgia. J Neurosurg 97: 347–353

    Article  PubMed  Google Scholar 

  • Pollock BE, Schoeberl KA (2010) Prospective comparison of posterior fossa exploration and stereotactic radiosurgery dorsal root entry zone target as primary surgery for patients with trigeminal neuralgia. Neurosurgery 67: 633–638

    Google Scholar 

  • Preul MC, Long PB, Brown JA, Velasco ME, Weaver MT (1990) Autonomic and histopathological effects of percutaneous ganglion compression in the rabbit. J Neurosurg 72: 933–940

    Article  CAS  PubMed  Google Scholar 

  • Pujol A (1787) Essai sur la maladie de la face, nommée le tic doloureux; avec quelques réflexions, sur le raptus caninus de Coelius Aurelianuas. Théophile Barrois, Paris

    Google Scholar 

  • Puusep L (1911) Über Behandlung von Neuralgien mittels Einspritzungen von Alkohol in den Nervenstamm. Arch f. Psych Nervenkrankh 48: 691–720

    Article  Google Scholar 

  • Rainov NG, Heidecke V (2003) Motor cortex stimulation for neuropathic facial pain. Neurol Res 25: 157–161

    Article  PubMed  Google Scholar 

  • Rand RW, Jacques DB, Melbye RW, Copcutt BG, Levenick MN, Fisher MR (1993) Leksell Gamma Knife treatment of tic douloureux. Stereotact Funct Neurosurg. 61 Suppl 1: 93–102

    Article  PubMed  Google Scholar 

  • Rand RW (1997) Leksell Gamma Knife treatment of tic douloureux. Neurosurg Clin N Am. 8:75–78

    CAS  PubMed  Google Scholar 

  • Rappaport ZH, Devor M (1994) Trigeminal neuralgia: the role of self-sustaining discharge in the trigeminal ganglion. Pain 56: 127–138

    Article  CAS  PubMed  Google Scholar 

  • Rasche D, Kress B, Schwark C, Wirtz CR, Unterberg A, Tronnier VM (2004) Treatment of trigeminal neuralgia associated with multiple sclerosis: case report. Neurology 63: 1714–1715

    Article  CAS  PubMed  Google Scholar 

  • Rasche D, Ruppolt M, Stippich C, Unterberg A, Tronnier VM (2006) Motor cortex stimulation for long-term relief of chronic neuropathic pain: a 10 year experience. Pain 121: 43–52

    Article  PubMed  Google Scholar 

  • Rasche D, Kress B, Stippich C, Nennig E, Sartor K, Tronnier VM (2006) Volumetric measurement of the pontomesencephalic cistern in patients with trigeminal neuralgia and healthy controls. Neurosurgery 59: 614–620

    Article  PubMed  Google Scholar 

  • Rasche D, Tronnier VM (2016) Clinical Significance of Invasive Motor Cortex Stimulation for Trigeminal Facial Neuropathic Pain Syndromes. Neurosurgery 79: 655–666

    Article  PubMed  Google Scholar 

  • Raslan AM, Nasseri M, Bahgat D, Abdu E, Burchiel KJ (2011) Motor cortex stimulation for trigeminal neuropathic or deafferentation pain: an institutional case series experience. Stereotact Funct Neurosurg 89: 83–88

    Article  PubMed  Google Scholar 

  • Rasmussen P, Laursen J, Simonsen P, Pdersen CB, Thomsen KA (1986) Chronic facial pain following diseases affecting the maxillary antrum. Acta neurochir 82: 39–42

    Article  CAS  PubMed  Google Scholar 

  • Régis J, Tuleasca C, Resseguier N, Carron R, Donnet A, Gaudart J, Levivier M (2016) Long-term safety and efficacy of Gamma Knife surgery in classical trigeminal neuralgia: a 497-patient historical cohort study. J Neurosurg 124: 1079–1087

    Article  PubMed  Google Scholar 

  • Revuelta R, Nathal E, Balderrama J, Tello A, Zenteno M (1993) External carotid artery fistula due to micocompression of the gasserian ganglion for relief of trigeminal neuralgia. J Neurosurg 78: 499–500

    Article  CAS  PubMed  Google Scholar 

  • Richards P, Shawdon H, Illingworth R (1983) Operative findings on microsurgical exploration of the cerebello-pontine angle in trigeminal neuralgia. J Neurol Neurosurg Psychiatry 46: 1098–1101

    Google Scholar 

  • Roldan P, Broseta J, Barcia-Salorio JL (1982) Chronic VPM stimulation for anesthesia dolorosa following trigeminal surgery. Appl Neurophysiol 45: 112–113

    CAS  PubMed  Google Scholar 

  • Römer KH (1955) Der Trigeminus – Monographie zur Chirurgie des fünften Hirnnerven. VEB Thieme Verlag, Leipzig

    Google Scholar 

  • Rose AS, Jacobson BM (1940) Treatment of trigeminal neuralgia with vitamin B1 (thiamine hydrochloride). Arch Neurol Psychiatry 44: 1307–1311

    Article  Google Scholar 

  • Rose W (1892) On the surgical treatment of trigeminal neuralgia. Lancet 139: Issue 3567: 71–73. Issue 3569: 182–184

    Google Scholar 

  • Ruland L (1953) Die periphere Elektrokoagulation als Behandlungsmethode gewisser Formen der Trigeminusneuralgie und schmerzhaften Neuromknoten. Chirurg 11: 502–503

    Google Scholar 

  • Rushton JG, Stevens JC, Miller RH (1981) Glossopharyngeal (vagoglossopharyngeal) neuralgia: a study of 217 cases. Arch Neurol 38: 201–205

    Article  CAS  PubMed  Google Scholar 

  • Rustagi A, Roychoudhury A, Bhutia O, Trikha A, Srivastava MV (2014) Lamotrigine Versus Pregabalin in the Management of Refractory Trigeminal Neuralgia: A Randomized Open Label Crossover Trial. J Maxillofac Oral Surg 13: 409–418

    Article  PubMed  Google Scholar 

  • Sahni KS, Pieper DR, Anderson R Baldwin NG (1990) Relation of hypesthesia to the outcome of glycerol rhizolysis for trigeminal neuralgia. J Neurosurg 72: 55–58

    Article  CAS  PubMed  Google Scholar 

  • Salar G, Baratto V, Ori C, Iob I, Mingrino S (1984) Percutaneous thermolesion of the glossopharyngeal nerve: Results and anatomo.phyiological considerations. Acta neurochir Suppl 33: 515–520

    Google Scholar 

  • Sampson JH, Grossi PM, Asaoka K, Fukushima T (2004) Microvascular decompression for glossopharyngeal neuralgia: long-term effectiveness and complication avoidance. Neurosurgery 54: 884–889

    Article  PubMed  Google Scholar 

  • Sandel T, Eide PK (2013) Long-term results of microvascular decompression for trigeminal neuralgia and hemifacial spasms according to preoperative symptomatology. Acta Neurochir 155: 1681–1692

    Article  PubMed  Google Scholar 

  • Schlichting JD (1768) Examen van Land en Zee-Chirurgie, Abraham Graal, Amsterdam

    Google Scholar 

  • Schlösser H (1903) Heilung peripherer Reizzustände sensibler und motorischer Nerven. Klin Monatsbl Augenheilkunde 61: 255

    Google Scholar 

  • Schlösser H (1907) Erfahrungen in der Neuralgiebehandlung yon Alkoholeinspritzungen. Verhandl Kongr Innere Med Wiesbaden

    Google Scholar 

  • Schürmann K, Butz M, Brock M (1972) temporal retrogasserian resection of trigeminal root versus controlled elective percutaneous electrocoagulation of the ganglion of Gasser in the treatment of trigeminal neuralgia. Report on a series of 531 cases. Acta neurochir 26: 33–35

    Article  PubMed  Google Scholar 

  • Shelden CH, Pudenz RH, Freshwater DB, Crue CB (1955) Compression rather than decompression for trigeminal neuralgia. J Neurosurg 12: 123–126

    Article  CAS  PubMed  Google Scholar 

  • Shelden CH, Crue BL, Coulter JH (1960) Surgical treatment of trigeminal neuralgia and discussion of compression operation. Postgrad Med X: 595–601

    Google Scholar 

  • Shelden CH, Pudenz RH, Doyle J (1967) Electrical control of facial pain. Am J Surg 114: 209–212

    Article  CAS  PubMed  Google Scholar 

  • Shoja MM, Tubbs RS, Khalili M, Khodadoost K, Loukas M, Cohen-Gadol AA (2010) Esmail Jorjani (1042–1137) and his descriptions of trigeminal neuralgia, hemifacial spasm, and Bell's palsy. Neurosurgery. 67: 431–434

    Article  PubMed  Google Scholar 

  • Shulev Y, Trashin A, Gordienko K (2011) Secondary trigeminal neuralgia in cerebellopontine angle tumors. Skull Base 21: 287–294

    Article  PubMed  PubMed Central  Google Scholar 

  • Sicard R, Robineau J (1920) Algie vélopharyngée essentielle: Traitement chirurgical. Rev Neurol 36: 256–257

    Google Scholar 

  • Siegfried J (1975) Results of percutaneous controlled thermocoagulation of the Gasserian ganglion in 300 cases of trigeminal pain. Adv. Neurosurg 3: 287–296

    Article  Google Scholar 

  • Siegfried J (1977) 500 percutaneous thermocogulations of the Gasserian ganglion for trigeminal pain. Surg Neurol 8: 126–131

    CAS  PubMed  Google Scholar 

  • Siegfried J, Vosmansky M (1975) Technique of the controlled thermocoagulation of trigeminal ganglion. Adv Neurosurg 2: 199–209

    Google Scholar 

  • Sindou M, Howeidy T, Acevedo G (2002) Anatomical observations during microvascular decompression for idiopathic trigeminal neuralgia (with correlations between topography of pain and site of the neurovascular conflict). Prospective study in a series of 579 patients. Acta Neurochir 144: 1–12

    Article  CAS  PubMed  Google Scholar 

  • Sindou M, Leston JM, Decullier E, Chapuis F (2008) Microvascular decompression for trigeminal neuralgia: the importance of a noncompressive technique--Kaplan-Meier analysis in a consecutive series of 330 patients. Neurosurgery 63(4 Suppl 2): 341–350

    PubMed  Google Scholar 

  • Sist T, Filadora V, Miner M, Lema M (1997) Gabapentin for idiopathic trigeminal neuralgia: report of two cases. Neurology 48: 1467

    Article  CAS  PubMed  Google Scholar 

  • Sjöquist O (1937) Eine neue Therapie bei Trigeminusneuralgie. Durchschneidung des Tractus spinalis trigemini. Zbl Neurochir 2: 274–281

    Google Scholar 

  • Sjöquist O (1938) Studies on pain conduction in the trigeminal nerve: a contribution to the surgical treatment of facial pain. Acta Psychiatr Neurol 17(Suppl): 1–139

    Google Scholar 

  • Skirving DJ, Dan NG (2001) A 20-year review of percutaneous balloon compression of the trigeminal ganglion. J Neurosurg 94: 913–917

    Article  CAS  PubMed  Google Scholar 

  • Slettebo H, Hirschberg H, Lindegaard KF (1993) Long-term results after percutaneous retrogasserian glycerol rhizotomy in patients with trigeminal neuralgia. Acta neurochir 122: 231–235

    Article  CAS  PubMed  Google Scholar 

  • Slotty PJ, Eisner W, Honey CR, Wille C, Vesper J (2015) Long-term follow-up of motor cortex stimulation for neuropathic pain in 23 patients. Stereotact Funct Neurosurg 93: 199–205

    Article  PubMed  Google Scholar 

  • Smith GW, Miller JM (1953) The treatment of tic doloureux with stilbamidine. Ann Int Med 38: 335–338

    Article  CAS  PubMed  Google Scholar 

  • Smith H, Joint C, Schlugman D, Nandi D, Stein JF, Aziz TZ (2001) Motor cortex stimulation for neuropathic pain. Neurosurg Focus 11: E2

    Article  CAS  PubMed  Google Scholar 

  • Smith KJ, McDonald WI (1982) Spontaneous and evoked electrical discharges from a central demyelinating lesion. J Neurol Sci 55: 39–47

    Article  CAS  PubMed  Google Scholar 

  • Smith ZA, De Salles AA, Frighetto L, Goss B, Lee SP, Selch M, Wallace RE, Cabatan-Awang C, Solberg T (2003) Dedicated linear accelerator radiosurgery for the treatment of trigeminal neuralgia. J Neurosurg 99: 511–516

    Article  PubMed  Google Scholar 

  • Smucker P, Bonnin JM, Pritz MB (2007) Teflon granuloma with midbrain cysts after microvascular decompression of the trigeminal nerve. Acta Neurochir 149: 537–539

    Article  CAS  PubMed  Google Scholar 

  • Spaziante R, Cappabianca P, Peca C, de Divitiis E (1988) Subarachnoid hemorrhage and „normal pressure hydrocephalus“: fatal complications of percutaneous microcompression of the gasserian ganglion. Case report. Neurosurgery 22: 148–151

    CAS  PubMed  Google Scholar 

  • Spiller WG, Frazier CH (1901) The division of the sensory root of the trigeminus for the relief of tic doloureux: an experimental, pathological and clinical study, with a preliminary report of one successfully treated patient. Univ. PA med. Bull 14: 341–352

    Google Scholar 

  • Steardo L, Leo A, Marano E (1984) Efficacy of baclofen in trigeminal neuralgia and some other painful conditions. A clinical trial. Eur Neurol 23: 51–55

    Article  CAS  PubMed  Google Scholar 

  • Steude U (1978) Percutaneous electro stimulation of the trigeminal nerve in patients with atypical trigeminal neuralgia. Neurochirurgia 21: 66–69

    CAS  PubMed  Google Scholar 

  • Surtees SJ, Hughes RR (1954) Treatment of trigeminal neuralgia with Vitamine B12. Lancet 1: 439–441

    Article  Google Scholar 

  • Sweet WH (1976) Treatment of facial pain by percutaneous differential thermorhizotomy. Progr Neurol Surg 7: 153–179

    Article  Google Scholar 

  • Sweet WH (1985) The history of development of treatment of trigeminal neuralgia. Clin Neurosurgery 32: 294–318

    CAS  Google Scholar 

  • Sweet WH (1986) The treatment of trigeminal neuralgia (tic doloureux). NEJM 315: 174–177

    Article  CAS  PubMed  Google Scholar 

  • Sweet WH, Poletti CE, Macon JB (1981) Treatment of trigeminal neuralgia and other facial pains by retrogasserian injection of glycerol. Neurosurgery 9: 647–653

    Article  CAS  PubMed  Google Scholar 

  • Sweet WH, Wepsic JG (1974) Controlled thermocoagulation of trigeminal ganglion and rootlets for differential destruction pain fibers. J Neurosurg 39: 139–156

    Google Scholar 

  • Sweet WH (1990) Treatment of trigeminal neuralgia by percutaneous rhizottomy. In: Youmans JR (Hrsg) Neurological Surgery, Philadelphia Saunders, S. 3888–3921

    Google Scholar 

  • Svien HJ, Love JG (1959) Results of decompression operation for trigeminal neuralgia four years plus after operation. J Neurosurg 16: 653–655

    Article  CAS  PubMed  Google Scholar 

  • Taptas N (1911) Les injections d´alcool dans le ganglion de Gasser à travers le trou ovale. Presse méd 19: 798–799

    Google Scholar 

  • Taarnhoj P (1952) Decompression of the trigeminal root and the posterior part of the ganglion as a treatment in trigeminal neuralgia. J Neurosurg 9: 288–290

    Article  CAS  PubMed  Google Scholar 

  • Tarricone R, Aguzzi G, Musi F, Fariselli L, Casaco A (2008) Cost-effectiveness analysis for trigeminal neuralgia: Cyberknife vs microvascular decompression. Neuropsych Dis Treatm 4: 647–652

    Google Scholar 

  • Tatli M, Satici O, Kanpolat Y, Sindou M (2008) Various surgical modalities for trigeminal neuralgia: literature study of respective long-term outcomes. Acta Neurochir 150: 243–255

    Article  CAS  PubMed  Google Scholar 

  • Taub E, Munz M, Tasker RR (1997) Chronic electrical stimulation of the gasserian ganglion for the relief of pain in a series of 34 patients. J Neurosurg 86: 197–202

    Article  CAS  PubMed  Google Scholar 

  • Tew J, Mayfield F (1973) Trigeminal neuralgia. A new surgical approach. Percutaneous electrocoagulation of the trigeminal nerve. Laryngoscope 83: 1096–1101

    PubMed  Google Scholar 

  • Tew JM jr. van Loveren HR (1988) Percutaneous rhizotomy in the treatment of intractable facial pain (trigeminal, glossopharyndeal and vagal nerves), in: Schmideck HH, Sweet WH (Hrsg) Current Techniques in Operative Neurosurgery. Orlando, Grune &Stratton, 1111–1123

    Google Scholar 

  • Thieme V (2016) Orofazialer Schmerz- Trigeminusneuralgie und posttraumatische Trigeminusneuropathie. Gemeinsamkeiten und Unterschiede. Schmerz 30: 99–117

    Article  CAS  PubMed  Google Scholar 

  • Thiry S (1962) Expérience personelle basée sur 225 cas de névralgie essentielle du trijumenau traités parélectrocoagulation stéréotaxique du ganglion de Gasser entre 1950 et 1960. Neurochirurgie 8: 86–92

    CAS  PubMed  Google Scholar 

  • Thiry S, Hotermann JM (1974) Traitement de névralgie essentielle du trijumeau par stéreotaxie el electrocoagulation partielle sélective du ganglion de Gasser. Expérience portant sur 365 cas traites entre 1950 et 1970. Neurochirurgie 20: 55–60

    Google Scholar 

  • Thurel R (1961a) Névralgie faciale et aloolisation du ganglion de Gasser. Rev Neurol 1961a: 104: 75–77

    Google Scholar 

  • Thurel R (1961b) Alcoolisation du ganglion du Gasser et diffusion de l´alcool aux formations nerveuses du voisinage. Rev Neurol 1961b: 104; 78–79

    Google Scholar 

  • Thurel R (1961c) Névralgie faciale et sclérose en plaques. Rev Neurol 1961c: 105; 346–347

    CAS  PubMed  Google Scholar 

  • Tönnis W, Kreissel H (1950) Die Traktotomie nach Sjöquist in der Behandlung der Trigeminusneuralgie. Zbl Chir 75: 873–882

    Google Scholar 

  • Tönnis W, Kreissel H (1951) Die Bedeutung einer sorgfältigen Differentialdiagnose für die chirurgische Behandlung der Trigeminusneuralgie. Dtsch Med Wochenschr 76: 1202–1205

    Article  PubMed  Google Scholar 

  • Tronnier V, Bremerich A, Miltner F (1988) Die Chemoneurolyse und Chemorhizolyse als selektive Behandlungsmöglichkeit von Malignomschmerzen im Mund-, Kiefer-, Gesichts- und Halsbereich. Tumordiagn 9: 106–110

    Google Scholar 

  • Tronnier V, Bremerich A, Danz B (1990) Diagnostik von Gesichtsschmerzen. Dtsch Med Wochenschr 115: 1018–1022

    Article  CAS  PubMed  Google Scholar 

  • Tronnier VM, Rasche D, Hamer J, Kienle AL, Kunze S (2001) Treatment of idiopathic trigeminal neuralgia: comparison of long-term outcome after radiofrequency rhizotomy and microvascular decompression. Neurosurgery 48: 1261–1267

    CAS  PubMed  Google Scholar 

  • Truini A, Haanpaa M, Provitera V, Biasiotta A, Stancanelli A, Caporaso G, Santoro L, Cruccu G, Nolano M (2015) Differential myelinated and unmyelinated sensory and autonomic skin nerve fiber involvement in patients with ophthalmic postherpetic neuralgia. Front Neuroanat 9: 105. https://doi.org/10.3389/fnana.2015.00105.eCollection2015

  • Turnbull I (1974) Percutaneous rhizotomy for trigeminal neuralgia. Surg Neurol 2: 385–392

    CAS  PubMed  Google Scholar 

  • Tyler-Kabara EC, Kassam AB, Horowitz MH, Urgo L, Hadjipanayis C, Levy EI, Chang YF (2002) Predictors of outcome in surgically managed patients with typical and atypical trigeminal neuralgia: comparison of results following microvascular decompression. J Neurosurg 96: 527–531

    Article  PubMed  Google Scholar 

  • Uihlein A, Love JG, Corbin KB (1955) Intracranial section oft he glossopharyngeal nerve. Arch Neurol Psychiat 74:320–324

    Article  CAS  Google Scholar 

  • Urgosík D, Vymazal J, Vladyka V, Liscák R (2000) Treatment of postherpetic trigeminal neuralgia with the gamma knife. J Neurosurg 93 Suppl 3: 165–168

    PubMed  Google Scholar 

  • Upadhyay SP, Rana SP, Mishra S, Bhatnagar S (2010) Successful treatment of an intractable postherpetic neuralgia (PHN) using peripheral nerve field stimulation (PFNS). Am J Hosp Pall Med 27: 59–62

    Article  Google Scholar 

  • Vadokas V, Ahyai A, Bockermann V, Markakis E (1994) Erfahrungen mit der retroganglionären Glycerin-Rhizotomie in der Behandlung der Trigeminusneuralgie. Schmerz 8: 216–221

    Article  CAS  PubMed  Google Scholar 

  • Van Buyten JP (2015) Trigeminal Ganglion Stimulation. Prog Neurol Surg 29: 76–82

    Article  PubMed  Google Scholar 

  • Van Buyten JP, Smet I, Van de Kelft E (2009) Electromagnetic navigation technology for more precise electrode placement in the foramen ovale: a technical report. Neuromodulation 12: 244–249

    Article  PubMed  Google Scholar 

  • Varela-Lema L, Lopez-Garcia M, Maceira-Rozas M, Munoz-Garzon V (2015) Linear accelerator stereotactic radiosurgery for trigeminal neuralgia. Pain Physician 18: 15–27

    PubMed  Google Scholar 

  • Velasco F, Argüelles C, Carrillo-Ruiz JD, Castro G, Velasco AL, Jiménez F, Velasco M (2008) Efficacy of motor cortex stimulation in the treatment of neuropathic pain: a randomized double-blind trial. J Neurosurg 108: 698–706

    Article  PubMed  Google Scholar 

  • Viellart, Pet. Maria, Praes Jos. Dussans. D (1768) utrum in pertinacibus capitis facieique doloribus aliquid prodesse possit section nervorum quinti partis? 4. Halleri Biblioth chirurg Tom II, Paris, S. 545

    Google Scholar 

  • Villavicencio AT, Lim M, Burneikiene S, Romanelli P, Adler JR, McNeely L, Chang SD, Fariselli L, McIntyre M, Bower R, Broggi G, Thramann JJ (2008) Cyberknife radiosurgery for trigeminal neuralgia treatment: a preliminary multicenter experience. Neurosurgery 62: 647–655

    Article  PubMed  Google Scholar 

  • Vilming ST, Lyberg T, Latase X (1986) Tizanidine in the management of trigeminal neuralgia. Cephalagia 6: 181–182

    Article  CAS  Google Scholar 

  • Vitali AM, Sayer FT, Honey CR (2007) Recurrent trigeminal neuralgia secondary to Teflon felt. Acta Neurochir 149: 719–722

    Article  CAS  PubMed  Google Scholar 

  • Wagner A (1869) Über nervösen Gesichtsschmerz und seine Behandlung durch Neurektomie. Arch Klin Chir 11; 1–126

    Google Scholar 

  • Walker AE (1942) Relief of pain by mesencephalic tractotomy. Arch Neurol 48: 865

    Article  Google Scholar 

  • Watson JC (2007) From paroxysmal to chronic pain in trigeminal neuralgia: implications of central sensitization. Neurology 69: 817–818

    Article  PubMed  Google Scholar 

  • Weisenburg TH (1910) Cerebello-pontine tumor diagnosed for six years as a tic doloreux. The symptoms of irritation of the ninth and twelfth cranial nerves. JAMA 54: 1600–1604

    Article  Google Scholar 

  • Wepfer JJ (1727) Observationes medico-practicae, de affectibus capitis internis et externis. Studio et opera Berhardini et Georgii Mich. Wepferi. Scaphusii, typ. et imp. J. A. Ziegleri

    Google Scholar 

  • Wiffen PJ, McQuay HJ, Moore RA (2005) Carbamazepine for acute and chronic pain. Cochrane Data Base Syst Rev CD005451

    Google Scholar 

  • William A, Azad TD, Brecher E, Cherry T, Bernstein I, Bruce DM, Rohrer S, Smith Z, William M, Sabelman E, Heit G, Pezeshkian P, Sedrak M (2016) Trigeminal and sphenopalatine ganglion stimulation for intractable craniofacial pain--case series and literature review. Acta Neurochir 158: 513–520

    Article  PubMed  Google Scholar 

  • Wilner PR, Haedicke TA (1948) Relapsing Kala-Azar – Report of a Case with Cure Effected by Stilbamidine. N Engl J Med 239: 250–253

    Article  CAS  PubMed  Google Scholar 

  • Wooddhall B, Odom GL (1955) Stilbamidine isethionate therapy of tic doloureux. J Neurosurg 12: 495–500

    Article  Google Scholar 

  • Yuan M, Zhou HY, Xiao ZL, Wang W, Li XL, Chen SJ, Yin XP, Xu LJ (2016) Efficacy and Safety of Gabapentin vs. Carbamazepine in the Treatment of Trigeminal Neuralgia: A Meta-Analysis. Pain Pract. 2016 Feb 19. doi: https://doi.org/10.1111/papr.12406. [Epub ahead of print]

  • Yoshino N, Akimoto H, Yamada I, Nagaoka T, Tetsumura A, Kurabayashi T, Honda E, Nakamura S, Sasaki T (2003) Trigeminal neuralgia: evaluation of neuralgic manifestation and site of neurovascular compression with 3D CISS MR imaging and MR angiography. Radiology 228: 539–545

    Article  PubMed  Google Scholar 

  • Young B, Shivazad A, Kryscio RJ, St Clair W, Bush HM (2013) Long-term outcome of high-dose γ knife surgery in treatment of trigeminal neuralgia. J Neurosurg 119: 1166–1175

    Article  PubMed  Google Scholar 

  • Young RF (1988) Glycerol rhizolysis for treatment of trigeminal neuralgia. J Neurosurg 69: 39–45

    Article  CAS  PubMed  Google Scholar 

  • Younis S, Maarbjerg S, Reimer M, Wolfram F, Olesen J, Baron R, Bendtsen L (2016) Quantitative sensory testing in classical trigeminal neuralgia-a blinded study in patients with and without concomitant persistent pain. Pain 15: 1407–1414

    Article  Google Scholar 

  • Yousry I, Moriggl B, Schmid UD, Naidich TP, Yousry TA (2005) Trigeminal ganglion and its divisions: Detailed anatomic MR Imaging with contrast-enhanced 3D constructive interference in the steady state sequences. AJNR Am J Neuroradiol 26: 1128–1135

    PubMed  Google Scholar 

  • Youssef AM, Gustin SM, Nash PG, Reeves JM, Petersen ET, Peck CC, Murray GM, Henderson LA (2014) Differential brain activity in subjects with painful trigeminal neuropathy and painful temporomandibular disorder. Pain 155: 467–475

    Article  PubMed  Google Scholar 

  • Zakrewska JM (1995) Trigeminal Neuralgia. Saunders, London, 1995

    Google Scholar 

  • Zakrzewska JM, Patsalos PN (1989) Oxcarbazepine: a new drug in the management of intractable trigeminal neuralgia. J Neurol Neurosurg Psychiatry 52: 472–476

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Zakrzewska JM, Patsalos PN (2002) Long-term cohort study comparing medical (oxcarbazepine) and surgical management of intractable trigeminal neuralgia. Pain 95: 259–266

    Article  CAS  PubMed  Google Scholar 

  • Zakrzewska JM, Thomas DG (1993) Patient's assessment of outcome after three surgical procedures for the management of trigeminal neuralgia. Acta Neurochir 122: 225–230

    Article  CAS  PubMed  Google Scholar 

  • Zhang H, Lei D, You C, Mao BY, Wu B, Fang Y (2013) The long-term outcome predictors of pure microvascular decompression for primary trigeminal neuralgia. World Neurosurg 79: 756–762

    Article  PubMed  Google Scholar 

  • Zenker R (1956) Die extrakraniellen Eingriffe bei der Trigeminusneuralgie einschließlich der Verödung des Ganglion Gasseri. in: Guleke RN, Zenker R (Hrsg.) Allgemeine und spezielle Operationslehre, Band 4, 2. Auflage Springer, Berlin, Heidelberg, S. 751–769

    Google Scholar 

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  1. Klinik für Neurochirurgie, Universitätsklinikum Schleswig-Holstein Campus Lübeck, Lübeck, Deutschland

    Prof. Dr. med. Volker Tronnier

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Tronnier, V. (2018). Chirurgische Therapie von Gesichtsschmerzen. In: Neurochirurgische Schmerztherapie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-53561-5_5

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