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Principles of Tumor Classification

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Coloproctology

Part of the book series: European Manual of Medicine ((EUROMANUAL))

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Abstract

Standard and uniform tumor classification is essential for the optimal care of patients with cancer. Both surgical and medical oncologists are increasingly using tumor classification along with genetic mutational analysis for prognostic and predictive purposes. Organizations such as the American Joint Committee on Cancer, World Health Organization, and Union for International Cancer Control are responsible for creating a common language for tumor classification and cancer staging. Appropriate standardized terminology is beneficial to all clinical practitioners. National pathology organizations are increasingly mandating standardized reporting of all cancer resection specimens.

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References

  1. Sobin LH, Gospodarowic MK, Wittekind C, editors. International Union Against Cancer (UICC), TNM classification of malignant tumors. 7th ed. New York: Wiley-Blackwell; 2009.

    Google Scholar 

  2. Edge S, Byrd D, Compton C, et al., editors. Colon and rectum. AJCC cancer staging manual. 7th ed. New York: Springer; 2010.

    Google Scholar 

  3. Bosman FT, Carneiro F, Hruban RH, Theise ND, editors. WHO classification of tumors of the digestive system. Lyon: IARC; 2010.

    Google Scholar 

  4. Dukes CE. The classification of cancer of the rectum. J Pathol Bacteriol. 1932;35:323–32.

    Article  Google Scholar 

  5. Turnbull Jr RB, Kyle K, Watson FR, et al. Cancer of the colon: the influence of the no touch isolation technic on survival rated. Ann Surg. 1967;166:420–7.

    Article  PubMed  PubMed Central  Google Scholar 

  6. Ramage JK, Goretzki PE, Manfredi R, et al. Consensus guidelines for the management of patients with digestive neuroendocrine tumors: well-differentiated colon and rectum tumor/carcinoma. Neuroendocrinology. 2008;87:31–9.

    Article  CAS  PubMed  Google Scholar 

  7. Quirke P, Morris E. Reporting colorectal cancer. Histopathology. 2007;50:103–12.

    Article  CAS  PubMed  Google Scholar 

  8. Quirke P, Steele R, Monson J, Grieve R, Khanna S, Couture J, et al. Effect of the plane of surgery achieved on local recurrence in patients with operable rectal cancer: a prospective study using data from the MRC CR07 and NCIC-CTG CO16 randomised clinical trial. Lancet. 2009;373:821–8.

    Article  PubMed  PubMed Central  Google Scholar 

  9. Williams G. Dataset for colorectal cancer, 2nd ed. UK: Royal College Of Pathologists; 2007 [updated 2007; cited 2007 September]; second edition. Available from: http://www.rcpath.org/index.asp?PageID=1153.

  10. West NP, Hohenberger W, Weber K, Perrakis A, Finan PJ, Quirke P. Complete mesocolic excision with central vascular ligation produces an oncologically superior specimen compared with standard surgery for carcinoma of the colon. J Clin Oncol. 2009;28:272–8.

    Article  PubMed  Google Scholar 

  11. Ryan R, Gibbons D, Hyland JM, Treanor D, White A, Mulcahy HE, et al. Pathological response following long-course neoadjuvant chemoradiotherapy for locally advanced rectal cancer. Histopathology. 2005;47:141–6.

    Article  CAS  PubMed  Google Scholar 

  12. Beddy D, Hyland JM, Winter DC, Lim C, White A, Moriarty M, Armstrong J, Fennelly D, Gibbons D, Sheahan K. A simplified tumor regression grade correlates with survival in locally advanced rectal carcinoma treated with neoadjuvant chemoradiotherapy. Ann Surg Oncol. 2008;15(12):3471–7.

    Article  CAS  PubMed  Google Scholar 

  13. Sobin LH, Wittekind CH, editors. International Union Against Cancer (UICC), TNM classification of malignant tumors. 5th ed. New York: Wiley-Liss Publications; 1997.

    Google Scholar 

  14. Sobin LH, Wittekind CH, editors. International Union Against Cancer (UICC), TNM classification of malignant tumors. 6th ed. New York: Wiley-Liss Publications; 2002.

    Google Scholar 

  15. Puppa G, Sonzogni A, Colombari R, Pelosi G. TNM staging system of colorectal carcinoma: a critical appraisal of challenging issues. Arch Pathol Lab Med. 2010;134:837–52.

    PubMed  Google Scholar 

  16. Jin M, Roth R, Rock JB, Washington MK, Lehman A, Frankel WL. The impact of tumor deposits on colonic adenocarcinoma AJCC TNM staging and outcome. Am J Surg Pathol. 2015;39:109–15.

    Article  PubMed  PubMed Central  Google Scholar 

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Correspondence to Kieran Sheahan MB, FRCPI FRCPATH .

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Sheahan, K. (2017). Principles of Tumor Classification. In: Herold, A., Lehur, PA., Matzel, K., O'Connell, P. (eds) Coloproctology. European Manual of Medicine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-53210-2_23

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  • DOI: https://doi.org/10.1007/978-3-662-53210-2_23

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-53208-9

  • Online ISBN: 978-3-662-53210-2

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