Skip to main content

Endometriosis

  • Chapter
  • First Online:
Coloproctology

Abstract

Endometriosis is the presence of endometrial-like tissue outside the uterus. It is common affecting 6–10 % of women during childbearing years and is recognized as a condition with significant social impact as related symptoms may heavily impact on patient quality of life. The digestive tract is involved in approximately one quarter of cases.

The diagnosis is suggested by the history, symptoms and physical signs and is supported by physical examination and imaging techniques (transvaginal and endorectal ultrasound, magnetic resonance and CT scan). Confirmation of the diagnosis relies on histological examination of specimens collected at time of surgery.

The etiology of endometriosis is unknown therefore treatment is not directed at a cure but at reducing related symptoms and improving quality of life. Medical treatment should be considered initially and bowel surgery should be reserved for intractable symptoms. Surgery is often very challenging because the infiltration of various structures by endometriotic nodules. The potential advantages of surgery have to be balanced with the risk of complications. Surgical treatment needs a multidisciplinary approach and a surgical team well-trained in pelvic and laparoscopic surgery. A laparoscopic approach is preferable. No clear guidelines exist concerning the relative advantages of peeling, disk or segmental resection in the treatment of intestinal nodules. Complete resection of deep infiltrative endometriosis with a low complication rate is likely to result in significant symptom improvement and quality of life in usually young patients. Therefore such surgery has to be performed in referral centres.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 79.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 99.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Viganò P, Parazzini F, Somigliana E, Vercellini P. Endometriosis: epidemiology and aetiological factors. Best Pract Res Clin Obstet Gynaecol. 2004;18:177–200.

    Article  PubMed  Google Scholar 

  2. Chamiè LP, Blasbalg R, Mendes Alves Pereira R, Warmbrand G, Serafini PC. Findings of pelvic endometriosis at transvaginal US, MR imaging and laparoscopy. Radiographics. 2011;31:E77–100.

    Article  PubMed  Google Scholar 

  3. Chapron C, Vieira M, Chopin N, Balleyguier C, Barakat H, Dumontier I, et al. Accuracy of rectal endoscopic ultrasonography and magnetic resonance imaging in the diagnosis of rectal involvement for patients presenting with deeply infiltrating endometriosis. Ultrasound Obstet Gynecol. 2004;24:175–9.

    Article  CAS  PubMed  Google Scholar 

  4. Bianconi L, Hummelshoj L, Coccia ME, Vigano P, Vittori G, Veit J, Music R, Tomassini A, D’Hooghe T. Recognizing endometriosis as a social disease: the European Union-encouraged Italian Senate approach. Fertil Steril. 2007;88:1285–7.

    Article  PubMed  Google Scholar 

  5. Bergqvist A. Extragenital endometriosis. A review. Eur J Surg. 1992;158:7–12.

    CAS  PubMed  Google Scholar 

  6. Chapron C, Chopin N, Borghese B, Foulot H, Dousset B, Vacher-Lavenu MC, Vieira M, Hasan W, Bricou A. Deeply infiltrating endometriosis: pathogenetic implications of the anatomical distribution. Hum Reprod. 2006;21:1839–45.

    Article  PubMed  Google Scholar 

  7. Piketty M, Chopin N, Dousset B, Millischer-Bellaische AE, Roseau G, Leconte M, Borghese B, Chapron C. Preoperative work-up for patients with deeply infiltrating endometriosis: transvaginal ultrasonography must definitely be the first-line imaging examination. Hum Reprod. 2009;24:602–7.

    Article  PubMed  Google Scholar 

  8. Revised American Society for Reproductive Medicine classification of endometriosis: 1996. Fertil Steril. 1997;67(5):817–21.

    Google Scholar 

  9. Haas D, Shebl O, Shamiyeh A, Oppelt P. The rASRM score and the Enzian classification for endometriosis: their strengths and weaknesses. Acta Obstet Gynecol Scand. 2013;92:3–7.

    Article  PubMed  Google Scholar 

  10. Ballard K, Lowton K, Wright J. What’s the delay? A qualitative study of women’s experiences of reaching a diagnosis of endometriosis. Fertil Steril. 2006;86:1296–301.

    Article  PubMed  Google Scholar 

  11. Vercellini P, Somigliana E, Vigano P, Abbiati A, Daguati R, Crosignani PG. Endometriosis: current and future medical therapies. Best Pract Res Clin Obstet Gynaecol. 2008;22:275–306.

    Article  PubMed  Google Scholar 

  12. Gelbaya TA, El-Halwagy HE. Focus on primary care: chronic pelvic pain in women. Obstet Gynecol Surv. 2001;56:757–64.

    Article  CAS  PubMed  Google Scholar 

  13. Roman H, Ness J, Suciu N, Bridoux V, Gourceroi G, Leroi AM, Tuech JJ, Ducrotté P, Savoye-Collet C, Savoye G. Are digestive symptoms in women presenting with pelvic endometriosis specific to lesion localizations? A preliminary prospective study. Hum Reprod. 2012;27:1–10.

    Google Scholar 

  14. Exacoustos C, Malzoni M, Di Giovanni A, Lazzeri L, Tosti C, Petraglia F, Zupi E. Ultrasound mapping system for the surgical management of deep infiltrating endometriosis. Fertil Steril. 2014;102:143–50.

    Article  PubMed  Google Scholar 

  15. Chamiè LP, et al. Transvaginal US after bowel preparation for DIE: protocol, imaging appaerances and laparoscopic correlation. Radiographics. 2010;30:1235–49.

    Article  PubMed  Google Scholar 

  16. Balleyguier C, Chapron C, Dubuisson JB, Kinkel K, Fauconnier A, Vieira M. Comparison of magnetic resonance imaging and transvaginal ultrasonography in diagnosing bladder endometriosis. J Am Assoc Gynecol Laparosc. 2002;9:15–23.

    Article  CAS  PubMed  Google Scholar 

  17. Biscaldi E, Ferrero S, Leone Roberti Maggiore U, Remorgida V, Venturini PL, Rollandi GA. Multidetector computerized tomography enema versus magnetic resonance enema in the diagnosis of rectosigmoid endometriosis. Eur J Radiol. 2014;83:261–7.

    Article  PubMed  Google Scholar 

  18. Schroder J, Lohnert M, Doniec JM, Dohrmann P. Endoluminal ultrasound diagnosis and operative management of rectal endometriosis. Dis Colon Rectum. 1997;40:614–7.

    Article  CAS  PubMed  Google Scholar 

  19. D’Hooghe T, Hummelshoj L. Multi-disciplinary centres/networks of excellence for endometriosis management and research: a proposal. Hum Reprod. 2006;21:2743–8.

    Article  PubMed  Google Scholar 

  20. Kennedy S, Bergqvist A, Chapron C, D’Hooghe T, Dunselman G, Greb R, et al. ESHRE guideline for the diagnosis and treatment of endometriosis. Hum Reprod. 2005;20:2698–704.

    Article  PubMed  Google Scholar 

  21. De Ziegler D, Borghese B, Chapron C. Endometriosis and infertility: pathophysiology and management. Lancet. 2010;376:730–8.

    Article  PubMed  Google Scholar 

  22. Abbott J, Hawe J, Hunter D, Holmes M, Finn P, Garry R. Laparoscopic excision of endometriosis: a randomized, placebo-controlled trial. Fertil Steril. 2004;82:878–84.

    Article  PubMed  Google Scholar 

  23. Johnson NP, Hummelshoj L, World Endometriosis Society Montpellier Consortium. Consensus on current management of endometriosis. Hum Reprod. 2013;28:1552–68.

    Article  PubMed  Google Scholar 

  24. Vercellini P, Fedele L, Aimi G, De Giorgi O, Consonni D, Crosignani PG. Reproductive performance, pain recurrence and disease relapse after conservative surgical treatment for endometriosis: the predictive value of the current classification system. Hum Reprod. 2006;21:2679–85.

    Article  PubMed  Google Scholar 

  25. Wills HJ, Reid GD, Cooper MJ, Morgan M. Fertility and pain outcomes following laparoscopic segmental bowel resection for colorectal endometriosis: a review. Aust N Z J Obstet Gynaecol. 2008;48:292–5.

    Article  PubMed  Google Scholar 

  26. Nezhat, Nezhat F, Ambroze W, Pennington E. Laparoscopic repair of small bowel and colon: a report of 26 cases. Surg Endosc. 1993;7:88–9.

    Article  CAS  PubMed  Google Scholar 

  27. Gordon SJ, Maher PJ, Woods R. Use of the CEEA stapler to avoid ultra-low segmental resection of a full-thickness rectal endometriotic nodule. J Am Assoc Gynecol Laparosc. 2001;8:312–6.

    Article  CAS  PubMed  Google Scholar 

  28. Landi S, Pontrelli G, Surico D, Ruffo G, Benini M, Soriano D, Mereu L, Minelli L. Laparoscopic disk resection for bowel endometriosis using a circular stapler and a new endoscopic method to control postoperative bleeding from the stapler line. J Am Coll Surg. 2008;207:205–9.

    Article  PubMed  Google Scholar 

  29. Woods RJ, Heriot AG, Chen FC. Anterior rectal wall excision for endometriosis using the circular stapler. ANZ J Surg. 2003;73:647–8.

    Article  PubMed  Google Scholar 

  30. Anaf V, El Nakadi I, Simon P, et al. Preferential infiltration of large bowel endometriosis along the nerves of the colon. Hum Reprod. 2004;19:996–1002.

    Article  CAS  PubMed  Google Scholar 

  31. Abrao MS, Podgaec S, Dias Jr JA, Gonçalves MO. Diagnosis of rectovaginal endometriosis. Hum Reprod. 2008;23:2386.

    Article  PubMed  Google Scholar 

  32. Abbott J, Hawe J, Clayton R, Garry R. The effects and effectiveness of laparoscopic excision of endometriosis: a prospective study with 2–5 year follow-up. Hum Reprod. 2003;9:1922–7.

    Article  Google Scholar 

  33. Chopin N, Vieira M, Borghese B, Foulot H, Dousset B, Coste J, et al. Operative management of deeply infiltrating endometriosis: results on pelvic pain symptoms according to a surgical classification. J Minim Invasive Gynecol. 2005;12:106–12.

    Article  PubMed  Google Scholar 

  34. Chapron C, Fauconnier A, Dubuisson JB, Barakat H, Vieira M, Bréart G. Deep infiltrating endometriosis: relation between severity of dysmenorrhoea and extent of disease. Hum Reprod. 2003;18:760–6,73.

    Article  PubMed  Google Scholar 

  35. Garry R, Clayton R, Hawe J. The effect of endometriosis and its radical laparoscopic excision on quality of life indicators. BJOG. 2000;107:44–54.

    Article  CAS  PubMed  Google Scholar 

  36. Noel JC, Chapron C, Fayt I, Anaf V. Lymph node involvement and lymphovascular invasion in deep infiltrating rectosigmoid endometriosis. Fertil Steril. 2008;89:1069–72.

    Article  PubMed  Google Scholar 

  37. Dousset B, Leconte M, Borghese B, Millischer AE, Roseau G, Arkwright S, Chapron C. Complete surgery for low rectal endometriosis: long-term results of a 100-case prospective study. Ann Surg. 2010;251:887–95.

    Article  PubMed  Google Scholar 

  38. Chapron C, Bourret A, Chopin N, Dousset B, Leconte M, Amsellem-Ouazana D. Surgery for bladder endometriosis: long-term results and concomitant management of associated posterior deep lesions. Hum Reprod. 2010;25:884–9.

    Article  PubMed  Google Scholar 

  39. Daraï E, Dubernard G, Coutant C, Frey C, Rouzier R, Ballester M. Randomized trial of laparoscopically assisted versus open colorectal resection for endometriosis: morbidity, symptoms, quality of life, and fertility. Ann Surg. 2010;251:1018–23.

    Article  PubMed  Google Scholar 

  40. Dowson HM, Bong JJ, Lovell DP, Worthington TR, Karanjia ND, Rockall TA. Reduced adhesion formation following laparoscopic versus open colorectal surgery. Br J Surg. 2008;95:909–14.

    Article  CAS  PubMed  Google Scholar 

  41. Wills HJ, Reid GD, Cooper MJW, Tsaltas J, Morgan M, Woods RJ. Bowel resection for severe endometriosis: an Australian series of 177 cases. Aust N Z J Obstet Gynaecol. 2009;49:415–8.

    Article  PubMed  Google Scholar 

  42. Daraï E, Bazot M, Rouzier R, Houry S, Dubernard G. Outcome of laparoscopic colorectal resection for endometriosis. Curr Opin Obstet Gynecol. 2007;19:308–13.

    Article  PubMed  Google Scholar 

  43. Ghezzi F, Cromi A, Ciravolo G, et al. A new laparoscopic-transvaginal technique for rectosigmoid resection in patients with endometriosis. Fertil Steril. 2008;90:1964–8.

    Article  PubMed  Google Scholar 

  44. Emmanuel KR, Davis C. Outcomes and treatment options in rectovaginal endometriosis. Curr Opin Obstet Gynecol. 2005;17:399–402.

    Article  PubMed  Google Scholar 

  45. Jerby BL, Kessler H, Falcone T, Milsom JW. Laparoscopic management of colorectal endometriosis. Surg Endosc. 1999;13:1125–8.

    Article  CAS  PubMed  Google Scholar 

  46. Dubernard G, Rouzier R, David-Montefiore E, Bazot M, Daraï E. Urinary complications after surgery for posterior deep infiltrating endometriosis are related to the extent of dissection and to uterosacral ligaments resection. J Minim Invasive Gynecol. 2008;15:235–40.

    Article  PubMed  Google Scholar 

  47. Fleisch MC, Xafis D, De Bruyne F, Hucke J, Bender HG, Dall P. Radical resection of invasive endometriosis with bowel or bladder involvement-long-term results. Eur J Obstet Gynecol Reprod Biol. 2005;123:224–9.

    Article  PubMed  Google Scholar 

  48. Koh CE, Juszczyk K, Cooper MJ, Solomon MJ. Management of deeply infiltrating endometriosis involving the rectum. Dis Colon Rectum. 2012;55:925–31.

    Article  PubMed  Google Scholar 

  49. Varol N, Maher P, Healey M, Woods R, Wood C, Hill D, Lolatgis N, Tsaltas J. Rectal surgery for endometriosis-should we be aggressive? J Am Assoc Gynecol Laparosc. 2003;10:182–9.

    Article  PubMed  Google Scholar 

  50. Dubernard G, Rouzier R, David-Montefiore E, Bazot M, Darai E. Use of the SF-36 questionnaire to predict quality-of-life improvement after laparoscopic colorectal resection for endometriosis. Hum Reprod. 2008;23:846–51.

    Article  CAS  PubMed  Google Scholar 

  51. Wright J, Lotfallah H, Jones K, Lovell D. A randomized trial of excision versus ablation for mild endometriosis. Fertil Steril. 2005;83:1830–6.

    Article  PubMed  Google Scholar 

  52. Healey M, Ang WC, Cheng C. Surgical treatment of endometriosis: a prospective randomized double-blinded trial comparing excision and ablation. Fertil Steril. 2010;94:2536–40.

    Article  PubMed  Google Scholar 

  53. Koninckx PR, Ussia A, Adamyan L, Wattiez A, Donnez J. Deep endometriosis: definition, diagnosis, and treatment. Fertil Steril. 2012;98:564–71.

    Article  PubMed  Google Scholar 

  54. Vercellini P, Barbara G, Abbiati A, Somigliana E, Viganò P, Fedele L. Repetitive surgery for recurrent symptomatic endometriosis: what to do? Eur J Obstet Gynecol Reprod Biol. 2009;146:15–21.

    Article  PubMed  Google Scholar 

  55. Guo SW. Recurrence of endometriosis and its control. Hum Reprod Update. 2009;15:441–61.

    Article  PubMed  Google Scholar 

  56. Shakiba K, Bena JF, McGill KM, Minger J, Falcone T. Surgical treatment of endometriosis: a 7-year follow-up on the requirement for further surgery. Obstet Gynecol. 2008;111:1285–92.

    Article  PubMed  Google Scholar 

  57. Jatan AK, Solomon MJ, Young J, Cooper M, Pathma-Nathan N. Laparoscopic management of rectal endometriosis. Dis Colon Rectum. 2006;49:169–74.

    Article  PubMed  Google Scholar 

  58. Armengol-Debeir L, Savoye G, Leroi AM, Gourcerol G, Savoye-Collet C, Tuech JJ, Vassilieff M, Roman H. Pathophysiological approach to bowel dysfunction after segmental colorectal resection for deep endometriosis infiltrating the rectum: a preliminary study. Hum Reprod. 2011;26:2330–5.

    Article  PubMed  Google Scholar 

  59. Ferrero S, Anserini P, Abbamonte LH, Ragni N, Camerini G, Remorgida V. Fertility after bowel resection for endometriosis. Fertil Steril. 2009;92:41–6.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Gian Andrea Binda M.D. .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2017 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Binda, G.A., Serventi, A., Fasciani, A. (2017). Endometriosis. In: Herold, A., Lehur, PA., Matzel, K., O'Connell, P. (eds) Coloproctology. European Manual of Medicine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-53210-2_20

Download citation

  • DOI: https://doi.org/10.1007/978-3-662-53210-2_20

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-53208-9

  • Online ISBN: 978-3-662-53210-2

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics