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Palliative chirurgische Verfahren des Magen- und Kardiakarzinoms

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Moderne Chirurgie des Magen- und Kardiakarzinoms

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Zusammenfassung

Während die komplette chirurgische R0-Resektion, oft im Rahmen multimodaler Therapiekonzepte, für Patienten mit Magenkarzinom die einzige Chance auf Kuration bietet, werden etwa 65 % aller an einem Magenkarzinom leidenden Patienten erst in einem lokal (zu) fortgeschrittenem und/oder metastasiertem Stadium diagnostiziert (Jemal et al. 2011, 2010, Ochenduszko et al. 2015). Palliative (chirurgische) Verfahren sind somit für gut zwei Drittel aller Patienten mit Magenkarzinom von besonderer Bedeutung.

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Literatur

  • Barkun AN, Bardou M, Kuipers EJ et al. (2010) International Consensus Upper Gastrointestinal Bleeding Conference G. International consensus recommendations on the management of patients with nonvariceal upper gastrointestinal bleeding. Ann Intern Med 152: 101–113. doi: 10.7326/0003-4819-152-2-201001190-00009

    Article  PubMed  Google Scholar 

  • Bentrem D, Wilton A, Mazumdar M et al. (2005) The value of peritoneal cytology as a preoperative predictor in patients with gastric carcinoma undergoing a curative resection. Ann Surg Oncol 12: 347–353. doi: 10.1245/ASO.2005.03.065

    Article  PubMed  Google Scholar 

  • Boerner T, Graichen A, Jeiter T et al. (2016) CRS-HIPEC prolongs survival but is not curative for patients with peritoneal carcinomatosis of gastric cancer. Ann Surg Oncol 23 (12): 3972–3977

    Article  CAS  Google Scholar 

  • Bozzetti F, Bonfanti G, Audisio RA et al. (1987) Prognosis of patients after palliative surgical procedures for carcinoma of the stomach. Surg Gynecol Obstet 164: 151–154

    CAS  PubMed  Google Scholar 

  • Cho JH, Lim JY, Choi AR et al. (2015) Comparison of surgery plus chemotherapy and palliative chemotherapy alone for advanced gastric cancer with Krukenberg tumor. Cancer Res Treat 47: 697–705. doi: 10.4143/crt.2013.175

    Article  CAS  PubMed  Google Scholar 

  • Coupe NA, Cox K, Clark K et al. (2013) Outcomes of permanent peritoneal ports for the management of recurrent malignant ascites. J Palliat Med 16: 938–940. doi: 10.1089/jpm.2012.0535

    Article  PubMed  Google Scholar 

  • Cunningham D, Starling N, Rao S et al. (2008) Upper Gastrointestinal Clinical Studies Group of the National Cancer Research Institute of the United K. Capecitabine and oxaliplatin for advanced esophagogastric cancer. N Engl J Med 358: 36–46. doi: 10.1056/NEJMoa073149

    Article  CAS  PubMed  Google Scholar 

  • Ebinger SM, Warschkow R, Tarantino I et al. (2015) Modest overall survival improvements from 1998 to 2009 in metastatic gastric cancer patients: a population-based SEER analysis. Gastric Cancer. doi: 10.1007/s10120-015-0541-9

    PubMed  Google Scholar 

  • Hartgrink HH, Putter H, Klein Kranenbarg E, Bonenkamp JJ et al. (2002) Dutch Gastric Cancer G. Value of palliative resection in gastric cancer. Br J Surg 89: 1438–1443. doi: 10.1046/j.1365-2168.2002.02220.x

    Article  CAS  PubMed  Google Scholar 

  • Heiss MM, Murawa P, Koralewski P et al. (2010) The trifunctional antibody catumaxomab for the treatment of malignant ascites due to epithelial cancer: Results of a prospective randomized phase II/III trial. Int J Cancer 127: 2209–2221. doi: 10.1002/ijc.25423

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Hioki M, Gotohda N, Konishi M et al. (2010) Predictive factors improving survival after gastrectomy in gastric cancer patients with peritoneal carcinomatosis. World J Surg 34: 555–562. doi: 10.1007/s00268-010-0396-5

    Article  PubMed  Google Scholar 

  • Jacquet P, Sugarbaker PH (1996) Clinical research methodologies in diagnosis and staging of patients with peritoneal carcinomatosis. Cancer Treat Res 82: 359–374

    Article  CAS  PubMed  Google Scholar 

  • Jemal A, Center MM, DeSantis C, Ward EM (2010) Global patterns of cancer incidence and mortality rates and trends. Cancer Epidemiol Biomarkers Prev 19: 1893–18907. doi: 10.1158/1055-9965.EPI-10-0437

    Article  PubMed  Google Scholar 

  • Jemal A, Bray F, Center MM et al. (2011) Global cancer statistics. CA Cancer J Clin 61: 69–90. doi: 10.3322/caac.20107

    Article  PubMed  Google Scholar 

  • Jeurnink SM, Steyerberg EW, van Hooft JE et al. (2010) Surgical gastrojejunostomy or endoscopic stent placement for the palliation of malignant gastric outlet obstruction (SUSTENT study): a multicenter randomized trial. Gastrointest Endosc 71: 490–499. doi: 10.1016/j.gie.2009.09.042

    Article  PubMed  Google Scholar 

  • Kim SW (2014) The result of conversion surgery in gastric cancer patients with peritoneal seeding. J Gastric Cancer 14: 266–270. doi: 10.5230/jgc.2014.14.4.266

    Article  PubMed  PubMed Central  Google Scholar 

  • Kim YI, Choi IJ (2015) Endoscopic management of tumor bleeding from inoperable gastric cancer. Clin Endosc 48: 121–127. doi: 10.5946/ce.48.2.121

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Kitayama J, Ishigami H, Kaisaki S et al. (2010) Weekly intravenous and intraperitoneal paclitaxel combined with S-1 for malignant ascites due to advanced gastric cancer. Oncology 78: 40–46. doi: 10.1159/000290955

    Article  CAS  PubMed  Google Scholar 

  • Koh JL, Yan TD, Glenn D, Morris DL (2009) Evaluation of preoperative computed tomography in estimating peritoneal cancer index in colorectal peritoneal carcinomatosis. Ann Surg Oncol 16: 327-333. doi: 10.1245/s10434-008-0234-2

  • Koizumi W, Narahara H, Hara T et al. (2008) Takeuchi M. S–1 plus cisplatin versus S-1 alone for first-line treatment of advanced gastric cancer (SPIRITS trial): a phase III trial. Lancet Oncol 9: 215–221. doi: 10.1016/S1470-2045(08)70035-4

    Article  CAS  PubMed  Google Scholar 

  • Kondoh C, Shitara K, Nomura Mchibana H (2015) Efficacy of palliative radiotherapy for gastric bleeding in patients with unresectable advanced gastric cancer: a retrospective cohort study. BMC Palliat Care 14: 37. doi: 10.1186/s12904–015–0034-y

  • Laine L, Jensen DM (2012) Management of patients with ulcer bleeding. Am J Gastroenterol 107: 345–360. quiz 361. doi: 10.1038/ajg.2011.480

    Article  CAS  PubMed  Google Scholar 

  • Lasithiotakis K, Antoniou SA, Antoniou GA et al. (2014) Gastrectomy for stage IV gastric cancer. a systematic review and meta-analysis. Anticancer Res 34: 2079–2085

    PubMed  Google Scholar 

  • Martella L, Bertozzi S, Londero AP et al. (2015) Surgery for liver metastases from gastric cancer: a meta-analysis of observational studies. Medicine (Baltimore) 94: e1113. doi: 10.1097/MD.0000000000001113

  • Mehta S, Hindmarsh A, Cheong E et al. (2006) Prospective randomized trial of laparoscopic gastrojejunostomy versus duodenal stenting for malignant gastric outflow obstruction. Surg Endosc 20: 239–242. doi: 10.1007/s00464-005-0130-9

    Article  CAS  PubMed  Google Scholar 

  • Mezhir JJ, Shah MA, Jacks LM et al. (2010) Positive peritoneal cytology in patients with gastric cancer: natural history and outcome of 291 patients. Ann Surg Oncol 17: 3173–3180. doi: 10.1245/s10434-010-1183-0

    Article  PubMed  Google Scholar 

  • Mezhir JJ, Posner MC, Roggin KK (2013) Prospective clinical trial of diagnostic peritoneal lavage to detect positive peritoneal cytology in patients with gastric cancer. J Surg Oncol 107: 794–798. doi: 10.1002/jso.23328

    Article  PubMed  Google Scholar 

  • Narayanan G, Pezeshkmehr A, Venkat S et al. (2014) Safety and efficacy of the PleurX catheter for the treatment of malignant ascites. J Palliat Med 17: 906–912. doi: 10.1089/jpm.2013.0427

    Article  PubMed  PubMed Central  Google Scholar 

  • No JH, Kim SW, Lim CH et al. (2013) Long-term outcome of palliative therapy for gastric outlet obstruction caused by unresectable gastric cancer in patients with good performance status: endoscopic stenting versus surgery. Gastrointest Endosc 78: 55–62. doi: 10.1016/j.gie.2013.01.041

    Article  PubMed  Google Scholar 

  • Ochenduszko S, Puskulluoglu M, Konopka K et al. (2015) Comparison of efficacy and safety of first-line palliative chemotherapy with EOX and mDCF regimens in patients with locally advanced inoperable or metastatic HER2-negative gastric or gastroesophageal junction adenocarcinoma: a randomized phase 3 trial. Med Oncol 32: 242. doi: 10.1007/s12032-015-0687-7

    Article  PubMed  PubMed Central  Google Scholar 

  • Okumura Y, Yamashita H, Aikou S et al. (2014) Palliative distal gastrectomy offers no survival benefit over gastrojejunostomy for gastric cancer with outlet obstruction: retrospective analysis of an 11-year experience. World J Surg Oncol 12: 364. doi: 10.1186/1477–7819-12-364

    Article  PubMed  PubMed Central  Google Scholar 

  • Randle RW, Swett KR, Swords DS et al. (2014) Efficacy of cytoreductive surgery with hyperthermic intraperitoneal chemotherapy in the management of malignant ascites. Ann Surg Oncol 21: 1474–1479. doi: 10.1245/s10434-013-3224-y

    Article  PubMed  Google Scholar 

  • Rudloff U, Langan RC, Mullinax JE et al. (2014) Impact of maximal cytoreductive surgery plus regional heated intraperitoneal chemotherapy (HIPEC) on outcome of patients with peritoneal carcinomatosis of gastric origin: results of the GYMSSA trial. J Surg Oncol 110: 275–284. doi: 10.1002/jso.23633

    Article  PubMed  Google Scholar 

  • Schumacher DL, Saclarides TJ, Staren ED (1994) Peritoneovenous shunts for palliation of the patient with malignant ascites. Ann Surg Oncol 1: 378–381

    Article  CAS  PubMed  Google Scholar 

  • Shridhar R, Dombi GW, Weber J et al. (2012) Adjuvant radiation therapy increases overall survival in node-positive gastric cancer patients with aggressive surgical resection and lymph node dissection: a SEER database analysis. Am J Clin Oncol 35: 216–221. doi: 10.1097/COC.0b013e31820dbf08

    Article  CAS  PubMed  Google Scholar 

  • Smith JK, Hill JS, Ng SC et al. (2010) Potential benefit of resection for stage IV gastric cancer: a national survey. J Gastrointest Surg 14: 1660–1668. doi: 10.1007/s11605-010-1351-3

    Article  PubMed  Google Scholar 

  • Sugarbaker PH (ed) (1996) Peritoneal carcinomatosis: principles of management. Kluwer, Boston

    Google Scholar 

  • Sung JJ, Chan FK, Chen M et al. (2011) Asia-Pacific Working Group consensus on non-variceal upper gastrointestinal bleeding. Gut 60: 1170–1177. doi: 10.1136/gut.2010.230292

    Article  PubMed  Google Scholar 

  • Tey J, Choo BA, Leong CN et al. (2015) Clinical outcome of palliative radiotherapy for locally advanced symptomatic gastric cancer in the modern era. Medicine (Baltimore) 93: e118. doi: 10.1097/MD.0000000000000118

  • Tiberio GA, Baiocchi GL, Morgagni P et al. (2015) Gastric cancer and synchronous hepatic metastases: is it possible to recognize candidates to R0 resection? Ann Surg Oncol 22: 589–596. doi: 10.1245/s10434-014-4018-6

    Article  PubMed  Google Scholar 

  • Tomiyama K, Takahashi M, Fujii T et al. (2006) Improved quality of life for malignant ascites patients by Denver peritoneovenous shunts. Anticancer Res 26: 2393–2395

    PubMed  Google Scholar 

  • Waddell T, Verheij M, Allum W et al. (2014) European Society for Medical O, European Society of Surgical O, European Society of R, Oncology. Gastric cancer: ESMO-ESSO-ESTRO clinical practice guidelines for diagnosis, treatment and follow-up. Eur J Surg Oncol 40: 584–591. doi: 10.1016/j.ejso.2013.09.020

    Article  CAS  PubMed  Google Scholar 

  • Watanabe A, Maehara Y, Okuyama T et al. (1998) Gastric carcinoma with pyloric stenosis. Surgery 123: 330–334

    Article  CAS  PubMed  Google Scholar 

  • Yang HK, Tsujinaka T, Nakamura K et al. (2015a) Randomized controlled trial of comparing gastrectomy (Gx) plus chemotherapy (CTX) with CTX alone in advanced gastric cancer (AGC) with a single non-curable factor: JCOG 0705/KGCA01 study (REGATTA). J Clin Oncol 33 (15 Suppl): 200

    CAS  Google Scholar 

  • Yang K, Liu K, Zhang WH et al. (2015b) The value of palliative gastrectomy for gastric cancer patients with intraoperatively proven peritoneal seeding. Medicine (Baltimore) 94: e1051. doi: 10.1097/MD.0000000000001051

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Authors and Affiliations

  1. Klinik und Poliklinik für Chirurgie, Universitätsklinikum Regensburg, Franz-Josef-Strauß-Allee 11, 93042, Regensburg, Deutschland

    C. Hackl

  2. Klinik und Poliklinik für Chirurgie, Universitätsklinikum Regensburg, Franz-Josef-Strauß-Allee 11, 93042, Regensburg, Deutschland

    M.H. Dahlke

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  1. C. Hackl
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Editors and Affiliations

  1. Klinik für Allgemein-, Viszeral- und Gefäßchirurgie, Charité Universitätsmedizin Berlin, Berlin, Berlin, Germany

    Martin E. Kreis

  2. Klinik für Allgemein-, Viszeral- und Gefäßchirurgie, Charité Universitätsmedizin Berliin, Berlin, Berlin, Germany

    Hendrik Seeliger

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Hackl, C., Dahlke, M. (2017). Palliative chirurgische Verfahren des Magen- und Kardiakarzinoms. In: Kreis, M., Seeliger, H. (eds) Moderne Chirurgie des Magen- und Kardiakarzinoms. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-53188-4_16

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  • DOI: https://doi.org/10.1007/978-3-662-53188-4_16

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