Skip to main content

Kaltes Atmosphärendruckplasma im Einsatz in der Chirurgie

  • Chapter
  • First Online:
Plasmamedizin

Zusammenfassung

Kaltes Atmosphärendruckplasma bietet vielfältige Anwendungsmöglichkeiten in allen chirurgischen Fachdisziplinen. Dazu gehört u. a. die Therapie chronischer und infizierter Wunden. In der Tumorchirurgie kann kaltes Atmosphärendruckplasma über eine relativ selektive Induktion von Apoptose in Tumorzellen sowohl zur Steigerung der lokalen Radikalität führen als auch in palliativen Konzepten eingesetzt werden. Weitere Möglichkeiten stellen die lokale Anwendung von kaltem Atmosphärendruckplasma zur intraoperativen Blutstillung sowie zur Behandlung von Implantaten zur Verbesserung der Einheilung und als Protektion vor Infektionen dar. Dabei scheint die Anwendung nach bisherigem Kenntnisstand keine unerwünschten systemischen Wirkungen zu haben. Die Chirurgie als traditionell innovative Fachdisziplin kann in Zusammenarbeit mit Grundlagenforschern die Anwendung von kaltem Atmosphärendruckplasma für die zukünftige klinische Routineanwendung in einem breiten Anwendungsfeld vorantreiben.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 64.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 84.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Literatur

  • Bazaka K, Jacob MV, Crowford RJ, Ivanova EP (2011) Plasma-assisted surface modfication of organic biopolymers to prevent bacterial attachment. Acta Biomater 7(5): 2015–2018

    Article  CAS  PubMed  Google Scholar 

  • Briem D, Strametz S, Schröder K, Meenen M, Lehmann W, Linhart W, Ohl A, Rueger JM (2005) Response of primary fibroblasts and osteoblasts to plasma treated polyetheretherketone (PEEK) surfaces. J Mater Sci Mater Med 16(7): 671–677

    Article  CAS  PubMed  Google Scholar 

  • Chong DST, Turner LA, Gadegaard N, Seifalian AM, Dalby MJ, Hamilton G (2015) Nanotopograhy and plasma treatment: redesigning the surface for vascular graft endothelialisation. Eur J Vasc Endocvasc Surg 49(3): 335–343

    Article  CAS  Google Scholar 

  • de Valence S, Tille JC, Chaabane C, Gurny R, Bochaton-Piallat ML, Walpoth BH, Möller M (2013) Plasma treatment for improving cell biocompatibility of a biodegradable polymer scaffold for vascular graft applications. Eur J Pharm Biopharm 85(1): 78–86

    Article  PubMed  Google Scholar 

  • Desmet T, Morent R, De Geyter N, Leys C, Schacht E, Dubruel P (2009) Nonthermal Plasma Technology as a Versatile Strategy for Polymeric Biomaterials Surface Modification: A Review. Biomacromolecules 10(9): 2351–2378

    Article  CAS  PubMed  Google Scholar 

  • Doppstadt C, Van der Linde J, Diedrich S, Evert K, Menges P, Matthes R, Partecke I, Weltmann KD, Heidecke CD (2013) Untersuchung zur intraperitonealen Anwendung von Tissue Tolerable Plasma (TTP) auf den Darm der Maus. Z Gastroenterol 51: K347

    Article  Google Scholar 

  • Ferraz EP, Sverzut AT, Freitas GP, Sá JC, Alves C jr, Beloti MM, Rosa AL (2015) Bone tissue response to plasma-nitrided titanium implant surfaces. J Appl Oral Sci 23(1): 9–13

    Article  PubMed  PubMed Central  Google Scholar 

  • Fridman G, Peddinghaus M, Ayan H, Fridman A, Balasubramanian M, Gutsol A, Brooks A, Friedman G (2006) Blood coagulation and living tissue sterilization by floating-electrode dielectric barrier discharge in air. Plasma Chem Plasma Process 26: 425–442

    Article  CAS  Google Scholar 

  • Fridman G, Fridmann G, Gutsol A, Shekhter AB, Vasilets VN, Fridman A (2008) Applied Plasma Medicine. Plasma Process Polymers 5(6): 503–533

    Article  CAS  Google Scholar 

  • Gomathi N, Sureshkumar A, Neogi S (2008) RF plasma-treated polymers for biomedical applications. Current Sci 94(11): 1478–1486

    CAS  Google Scholar 

  • Hauser J, Krüger CD, Halfmann H, Awakowicz P, Köller M, Esenwein SA (2009) Surface modification of metal implant materials by low-pressure plasma treatment. Biomed Tech Biomed Engin 54(2): 98–106

    Article  CAS  Google Scholar 

  • Lee OJ, Ju HW, Khang G, Sun PP, Rivera J, Cho JH, Park SJ, Eden JG, Park CH (2015) An experimental burn wound-healing study of non-thermal atmospheric pressure microplasma jet arrays. J Tissue Eng Regen Med 10(4): 348–357. doi: 10.1002/term.2074

    Article  PubMed  Google Scholar 

  • Loya MC, Brammer KS, Choi C, Chen LH, Jin S (2010) Plasma-induced nanopillars on bare metal coronary stent surface for enhanced endothelialization. Acta Biomater 6(12): 4589–4595

    Article  CAS  PubMed  Google Scholar 

  • Martins A, Pinho ED, Faria S, Pashkuleva I, Marques AP, Reis RL, Neves NM (2009) Surface modification of electrospun polycaprolactone nanofiber meshes by plasma treatment to enhance biological performance. Small 5: 1195–1206

    CAS  PubMed  Google Scholar 

  • Masur K, von Behr M, Bekeschus S, Weltmann KD, Hackbarth C, Heidecke CD, von Bernstorff W, von Woedtke T, Partecke LI (2015) Synergistic inhibition of tumor cell proliferation by cold plasma and gemcitabine. Plasma Processes Polymers 12(12): 1377–1382

    Article  CAS  Google Scholar 

  • Partecke LI, Evert K, Haugk J, Doering F, Normann L, Diedrich S, Weiss FU, Evert M, Huebner NO, Guenther C, Heidecke CD, Kramer A, Bussjahn R, Weltmann KD, Pati O, Bender C, von Bernstorff W (2012) Tissue Tolerable Plasma (TTP) induces apoptosis in pancreatic cancer cells in vitro and in vivo. BMC Cancer 12: 473

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Raiser J, Zenker M (2006) Argon plasma coagulation for open surgical and endoscopic applications: state of the art. J Physics D Appl Phys 39: 3520–3523

    Article  CAS  Google Scholar 

  • Riskin DJ, Longaker MT, Gertner M, Krummel TM (2006) Innovation in Surgery: A Historical Perspective. Ann Surg 244(5): 686–693

    Article  PubMed  PubMed Central  Google Scholar 

  • Seker E, Kilicarslan MA, Deniz ST, Mumcu E, Ozkan P (2015) Effect of atmospheric plasma versus conventional surface treatments on the adhesion capability between self-adhesive resin cement and titanium surface. J Adv Prosthodont 7(3): 249–256

    Article  PubMed  PubMed Central  Google Scholar 

  • Seon GM, Seo HJ, Kwon SY, Lee MH, Kwon BJ, Kim MS, Koo MA, Park BJ, Park JC (2015) Titanium surface modification by using microwave-induced argon plasma in various conditions to enhance osteoblast biocompatibility. Biomater Res 19: 13

    Article  PubMed  PubMed Central  Google Scholar 

  • Steinbeck MJ, Chernets N, Zhang J, Kurpad DS, Friedman G, Fridman A, Freeman TA (2013) Skeletal cell differentiation is enhanced by atmospheric dielectric barrier discharge plasma treatment. PLoS One 8(12): e82143

    Article  Google Scholar 

  • Tan F, O’Neill F, Naciri M, Dowling D, Al-Rubeai M (2012) Cellular and transcriptomic analysis of human mesenchymal stem cell response to plasma-activated hydroxyapatite coating. Acta Biomater 8(4): 1627–1638

    Article  CAS  PubMed  Google Scholar 

  • Testrich H, Rebl H, Finke B, Hempel F, Nebe B, Neichsner J (2013) Aging effects of plasma polymerized ethylenediamine (PPEDA) thin films on cell-adhesive implant coatings. Mater Sci Eng C Mater Biol Appl 33(7): 3875–3880

    Article  CAS  PubMed  Google Scholar 

  • Walter G, Hoffmann R (2009) Implantat-assoziierte Infektionen in Orthopädie und Unfallchirurgie. Krankenhaus-Hygiene + Infektionsverhütung 31: 8–14

    Article  Google Scholar 

  • Wodtke J, Löhr JF (2008) Das infizierte Implantat. Orthopäde 37(3): 257–269

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2016 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Partecke, L.I., Liedtke, K.R. (2016). Kaltes Atmosphärendruckplasma im Einsatz in der Chirurgie. In: Metelmann, HR., von Woedtke, T., Weltmann, KD. (eds) Plasmamedizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-52645-3_7

Download citation

  • DOI: https://doi.org/10.1007/978-3-662-52645-3_7

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-52644-6

  • Online ISBN: 978-3-662-52645-3

  • eBook Packages: Medicine (German Language)

Publish with us

Policies and ethics