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Aktueller und perspektivischer Einsatz kalter Plasmen aus hygienischer Indikation

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Zusammenfassung

Kalte Plasmen zeigen eine hohe Wirksamkeit gegen Mikroorganismen und Viren sowie gegen bakterielle und fungielle Biofilme bei gleichzeitiger Verträglichkeit für die Körperoberfläche sowie für unbelebte Materialien. Darüber hinaus besteht die Möglichkeit der gezielten Modifikation der Eigenschaften von Mikroorganismen. Polymere und metallische Oberflächen werden durch Plasmabehandlung in ihrer Hydrophobizität verändert; zugleich können Beschichtungen aufgebracht werden. Durch inflammatorische Reize, Förderung der Angiogenese und der Proliferation von Fibroblasten, Keratinozyten und Osteoblasten werden Heilungsprozesse in Gang gesetzt.

Folgende Hygieneanwendungen sind etabliert bzw. zeichnen sich als aussichtsreich ab: Sterilisation, Dekontamination von Medizinprodukten, Lebensmitteln, Verpackungsmaterialien, Boden, Abwasser und Raumluft. Perspektivische Anwendungen beinhalten die Leistungsoptimierung biotechnologisch eingesetzter Mikroorganismen, die Verbesserung der Biokompatibilität und -funktionalität von Implantatoberflächen und die Impfstoffherstellung. Auf der Körperoberfläche steht die Wundbehandlung im Fokus. Präoperative Hautantiseptik, Antiseptik in der Mundhöhle und die Inaktivierung von Parasiten sind mögliche zukünftige Einsatzbereiche.

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Authors and Affiliations

  1. Universitätsmedizin Greifswald Institut für Hygiene und Umweltmedizin, Walther-Rathenau-Str. 49a, 17485, Greifswald, Deutschland

    Axel Kramer

  2. Leibniz-Institut für Plasmaforschung und Technologie e.V. (INP), Felix-Hausdorff-Straße 2, 17489, Greifswald, Deutschland

    Rutger Matthes

  3. Universitätsmedizin Greifswald Zentrum für Zahn-, Mund- und Kieferheilkunde Abt. Parodontologie-Wissenschaftliches Forschungslabor, Rotgerberstraße 8, 17475, Greifswald, Deutschland

    Rutger Matthes

  4. Leibniz-Institut für Plasmaforschung und Technologie e.V. (INP) ZIK plasmatis, Felix-Hausdorff-Straße 2, 17489, Greifswald, Deutschland

    Sander Bekeschus

  5. Universitätsmedizin Greifswald Institut für Hygiene und Umweltmedizin, Walther-Rathenau-Straße 49a, 17485, Greifswald, Deutschland

    Claudia Bender

  6. Universitätsmedizin Greifswald Zentrum für OrthopädieUnfallchirurgie und Rehabilitative MedizinKlinik und Poliklinik für Unfall-Wiederherstellungschirurgie und Rehabilitative Medizin, Ferdinand-Sauerbruch-Straße, 17475, Greifswald, Deutschland

    Matthias Napp

  7. Universitätsklinikum Rostock Klinik und Poliklinik für Anästhesiologie und Intensivtherapie, Schillingallee 35, 18057, Rostock, Deutschland

    Olaf Lademann

  8. Charité – Universitätsmedizin Berlin Klinik für Dermatologie, Venerologie und Allergologie, Bereich Hautphysiologie, Charitéplatz 1, 10117, Berlin, Deutschland

    Jürgen Lademann

  9. Leibniz-Institut für Plasmaforschung und Technologie e.V. (INP), Felix-Hausdorff-Straße 2, 17489, Greifswald, Deutschland

    Klaus Dieter Weltmann

  10. Tierarztpraxen Karrin & Lubmin, Karrin 15, 17440, Kröslin, Deutschland

    Claudia Bender

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  1. Axel Kramer
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  5. Matthias Napp
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  6. Olaf Lademann
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  8. Klaus Dieter Weltmann
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Editors and Affiliations

  1. Universitätsmedizin Greifswald, Mund-Kiefer-Gesichtschirurgie/Plastische Operation , Greifswald, Germany

    Hans-Robert Metelmann

  2. Technologie e.V., Leibniz-Institut für Plasmaforschung und Technologie e.V., Greifswald, Germany

    Thomas von Woedtke

  3. Leibniz-Institut für Plasmaforschung und Technologie e.V., Leibniz-Institut für Plasmaforschung und Technologie e.V., Greifswald, Germany

    Klaus-Dieter Weltmann

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Kramer, A. et al. (2016). Aktueller und perspektivischer Einsatz kalter Plasmen aus hygienischer Indikation. In: Metelmann, HR., von Woedtke, T., Weltmann, KD. (eds) Plasmamedizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-52645-3_11

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