Skip to main content

Zusammenfassung

Migräne ist eine Erkrankung, die medizinisch und psychologisch gut erforscht ist. Dennoch gibt es sehr viele Irrtümer und Halbwahrheiten, die nur scheinbare Behandlungssicherheiten schaffen. In diesem Kapitel werden evidenzbasierte und auch klinisch plausible Befunde aufgezeigt. Klinische Muster der Migräne, ihre Klassifikation und Epidemiologie werden so dargestellt, dass sich der Leser oder die Leserin auch ohne spezielle Vorerfahrungen in diesem Störungsbild ausreichend orientieren kann. Es werden Befunde insbesondere aus den letzten Jahren zur Ätiopathogenese und zu medizinischen und psychologischen Therapieansätzen dargestellt. Darüber hinaus werden auch syndromspezifische psychologische Behandlungsmöglichkeiten aufgezeigt, deren Evidenznachweis zum Teil noch aussteht, die sich aber aus den Pathomechanismen der Migräne herleiten und die Chance bieten, in Zukunft nicht nur die Krankheitsbewältigung zu verbessern, sondern auch direkt in den Krankheitsprozess einzugreifen.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 69.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 89.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Literatur

  • Aurora SK, Wilkinson F (2007) The brain is hyperexcitable in migraine. Cephalalgia 27: 1442–1453

    Google Scholar 

  • Aurora SK, Winner P, Freeman MC, Spierings EL, Heiring JO, DeGryse RE, VanDenburgh AM, Nolan ME, Turkel CC (2011) Onabotulinumtoxin A for treatment of chronic migraine: pooled analyses of the 56-week PREEMPT clinical program. Headache 51: 1358–1373

    Google Scholar 

  • Basler HD, Kröner-Herwig B (1998) Psychologische Schmerztherapie bei Kopf- und Rückenschmerzen: Das Marburger Schmerzbewältigungsprogramm zur Gruppen- und Einzeltherapie, 2. Aufl. Quintessenz, München

    Google Scholar 

  • Becker WJ (2013) The premonitory phase of migraine and migraine management. Cephalalgia 33: 1117–1121

    Google Scholar 

  • Bigal M (2009) Migraine chronification – concept and risk factors. Discov Med 8: 145–150

    Google Scholar 

  • Biondi DM (2005) Physical treatments for headache: a structured review. Headache 45: 738–746

    Google Scholar 

  • Brandt J, Celentano D, Stewart WF, Liner M, Folstein MF (1990) Personality and emotional disorder in a community sample of migraine headache sufferers. Am J Psychiatry 147: 303–308

    Google Scholar 

  • Breslau N, Davis GC, Schultz LR, Paterson EL (1994) Migraine and major depression: a longitudinal study. Headache 34: 387–393

    Google Scholar 

  • Busch V, Gaul C (2008) Exercise in migraine therapy – is there any evidence for efficacy? A critical review. Headache 48: 890–899

    Google Scholar 

  • Campbell JK, Penzien DB, Wall EM (2000) Evidence-based guidelines for migraine headaches: behavioural and psychological treatments. American Academy of Neurology. http://search.pedro.org.au/search-results/record-detail/9764. Zugegriffen: 02. März 2016

  • Cevoli S, Giannini G, Favoni V, Pierangeli G, Cortelli P (2012) Migraine and sleep disorders. Neurol Sci 33 (Suppl 1): S43–S46

    Google Scholar 

  • Chadaide Z, Arlt S, Antal A, Nitsche MA, Lang N, Paulus W (2007) Transcranial direct current stimulation reveals inhibitory deficiency in migraine. Cephalalgia 27: 833–839

    Google Scholar 

  • Chong CD, Starling AJ, Schwedt TJ (2015) Interictal photosensitivity associates with altered brain structure in patients with episodic migraine. Cephalalgia. doi: 10.1177/ 0333102415606080

    Google Scholar 

  • Cinciripini PA, Williamson DA, Epstein LH (1981) Behavioral treatment of migraine headache. In: Ferguson JM, Taylor CB (eds) The comprehensive handbook of behavioral medicine. Vol 2: Syndromes and special areas. MTP Press, Lancaster

    Google Scholar 

  • Dahlöf CGH, Dimenäis E (1995) Migraine patients experience poorer subjective well-being quality of life even between attacks. Cephalalgia 15: 31–36

    Google Scholar 

  • de Tommaso M, Ambrosini A, Brighina F, Coppola G, Perrotta A, Pierelli F, Sandrini G, Valeriani M, Marinazzo D, Stramaglia S, Schoenen J (2014) Altered processing of sensory stimuli in patients with migraine. Nat Rev Neurol 10: 144–155

    Google Scholar 

  • Denecke H, Kröner-Herwig B (2000) Kopfschmerztherapie mit Kindern und Jugendlichen. Hogrefe, Göttingen

    Google Scholar 

  • Diener HC, Kronfeld K, Boewing G et al (2006a) Efficacy of acupuncture for the prophylaxis of migraine: a multicentre randomised controlled clinical trial. Lancet Neurol 5: 310–316

    Google Scholar 

  • Diener HC, Gendolla A, Meier U, Wollny M (2006b) Integrierte Versorgung Kopfschmerz. Info Neurologie Psychiatrie 8: 33–34

    Google Scholar 

  • Diener HC, Küper M, Kurth T (2008) Migraine-associated risks and comorbidity. J Neurol 255(9): 1290–1301

    Google Scholar 

  • Eccleston C, Palermo TM, Williams AC, Lewandowski Holley A, Morley S, Fisher E, Law E (2014) Psychological therapies for the management of chronic and recurrent pain in children and adolescents. Cochrane Database Syst Rev 5: CD003968

    Google Scholar 

  • Etminan M, Takkouche B, Isorna FC, Samii A (2005) Risk of ischaemic stroke in people with migraine: systematic review and meta-analysis of observational studies. BMJ 330(7482): 63

    Google Scholar 

  • Ernst E (1999) Homeopathic prophylaxis of headache and migraine. A systematic review. J Pain Symptom Manage 18: 353–357

    Google Scholar 

  • Evers S, Afra J, Frese A, Goadsby PJ, Linde M, May A, Sandor PS (2009) European Federation of Neurological Societies. EFNS guideline on the drug treatment of migraine – revised report of an EFNS task force. Eur J Neurol 16(9): 968–981

    Google Scholar 

  • Fritsche G, Gaul C (2013) Multimodale Therapie bei chronischen Kopfschmerzen. Thieme, Stuttgart

    Google Scholar 

  • Fritsche G, Kröner-Herwig B, Kropp P, Niederberger U, Haag G (2013) Psychological therapy of migraine: systematic review. Schmerz 27: 263–274

    Google Scholar 

  • Gaul C (2014) Kopfschmerzen – Patientenschulung als Baustein multimodaler Therapieprogramme. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 57: 961–966

    Google Scholar 

  • Gaul C, van Doorn C, Webering N, Dlugaj M, Katsarava Z, Diener HC, Fritsche G (2011a) Clinical outcome of a headache specific multidisciplinary treatment program and adherence to treatment recommendations in a tertiary headache center. An observational study. J Headache Pain 12: 475–483

    Google Scholar 

  • Gaul C, Brömstrup J, Fritsche G, Diener HC, Katsarava Z (2011b) Evaluating integrated headache care: a one-year follow-up observational study in patients treated at the Essen headache centre. BMC Neurol 11: 124

    Google Scholar 

  • Gaul C, Liesering-Latta E, Schäfer B, Fritsche G, Holle D (2015) Integrated multidisciplinary care of headache disorders: A narrative review. Cephalalgia. doi: 10.1177/ 0333102415617413

    Google Scholar 

  • Gerber WD, Kropp P, Schoenen J, Siniatchkin MS (1996) »Born to be wild oder doch gelernt?« Neue verhaltensmedizinische Erkenntnisse zur Ätiopathogenese der Migräne. Verhaltenstherapie 6: 210–220

    Google Scholar 

  • Goadsby PJ, Edvinsson L, Ekman R (1988) Release of vasoactive peptides in the extracerebral circulation of humans and the cat during activation of the trigeminovascular system. Ann Neurol 23: 193–196

    Google Scholar 

  • Graham JR, Wolff HG (1938) Mechanism of migraine headache and action of ergotamine tartrate. Arch Neurol Psychiatry 39: 737–763

    Google Scholar 

  • Hadjikhani N, Sanchez Del Rio M, Wu O et al (2001) Mechanisms of migraine aura revealed by functional MRI in human visual cortex. Proc Natl Acad Sci USA 98: 4687–4692

    Google Scholar 

  • Hashizume M, Yamada U, Sato A et al (2008) Stress and psychological factors before a migraine attack: a time-based analysis. Biopsychosoc Med 2: 14

    Google Scholar 

  • Henryk-Gutt R, Rees WL (1973) Psychological aspects of migraine. J Psychosom Med 17: 141–153

    Google Scholar 

  • Hering R, Couturier EG, Steiner TJ (1992) Weekend migraine in men. Lancet 339: 67

    Google Scholar 

  • Heuser J (2000) Biofeedback bei chronischen Kopfschmerzen. Verhaltenstherapie 10: 249–257

    Google Scholar 

  • Holm JE, Lamberty K, McSherry WC, Davis PA (1997) The stress response in headache sufferers: physiological and psychological reactivity. Headache 37: 221–227

    Google Scholar 

  • Holzhammer J, Wöber C (2006) Alimentary trigger factors that provoke migraine and tension-type headache. Schmerz 20: 151–159

    Google Scholar 

  • Houtveen JH, Sorbi M (2013) Prodromal functioning of migraine patients relative to their interictal state – an ecological momentary assessment study. PLoS One 8: e72827

    Google Scholar 

  • IHS – Headache Classification Committee of the International Headache Society (2004) The International Classification of Headache Disorders, 2nd ed. ICHD-II. Cephalalgia 24 (Suppl 1): 1–160

    Google Scholar 

  • IHS – Headache Classification Committee of the International Headache Society (2013) The International Classification of Headache Disorders, 3rd edition (beta version). Cephalalgia 33: 629–808

    Google Scholar 

  • Karatas H, Erdener SE, Gursoy-Ozdemir Y, Lule S, Eren-Koçak E, Sen ZD, Dalkara T (2013) Spreading depression triggers headache by activating neuronal Panx1 channels. Science 339: 1092–1095

    Google Scholar 

  • Kelman L (2004) The premonitory symptoms (prodrome): a tertiary care study of 893 migraineurs. Headache 44: 865–872

    Google Scholar 

  • Kelman L (2006) The postdrome of the acute migraine attack. Cephalalgia 26: 214–220

    Google Scholar 

  • Kelman L (2007) The triggers or precipitants of the acute migraine attack. Cephalalgia 27: 394–402

    Google Scholar 

  • Khan S, Schoenen J, Ashina M (2014) Sphenopalatine ganglion neuromodulation in migraine: what is the rationale? Cephalalgia 34: 382–391

    Google Scholar 

  • Knapp TW (1983) Migräne. Bd 1: Symptomatologie und Ätiologie. Beltz, Weinheim

    Google Scholar 

  • Kröner-Herwig B, Ruhmland M, Zintel W, Siniatchkin M (2005) Are migraineurs hypersensitive? A test of the stimulus processing disorder hypothesis. Eur J Pain 9: 661–671

    Google Scholar 

  • Kröner-Herwig B, Heinrich M, Morris L (2007) Headache in German children and adolescents: a population-based epidemiological study. Cephalalgia 27: 519–527

    Google Scholar 

  • Kropp P, Muller B, Gerber WD (2007) Long-lasting migraine alters amplitudes and habituation of contingent negative variation. Cephalalgia 27: 666

    Google Scholar 

  • Lance JW (1991) Solved and unsolved headache problems. Headache 31: 439–445

    Google Scholar 

  • Levin M (2004) Chronic daily headache and the revised international headache society classification. Curr Pain Headache Rep 8: 59–65

    Google Scholar 

  • Lieba-Samal D, Wöber C, Frantal S, Brannath W, Schmidt K, Schrolnberger C, Wöber-Bingöl C; PAMINA study group (2011) Headache, menstruation and combined oral contraceptives: a diary study in 184 women with migraine. Eur J Pain 15: 852–857

    Google Scholar 

  • Lipton R, Scher A, Kolodner K, Liberman J, Steiner T, Stewart W (2002) Migraine in the United States: epidemiology and patterns of health care use. Neurology 58: 885–894

    Google Scholar 

  • Lipton RB, Buse DC, Hall CB, Tennen H, Defreitas TA, Borkowski TM, Grosberg BM, Haut SR (2014) Reduction in perceived stress as a migraine trigger: testing the »let-down headache« hypothesis. Neurology 82: 1395–1401

    Google Scholar 

  • Lipton RB, Fanning KM, Serrano D, Reed ML, Cady R, Buse DC (2015) Ineffective acute treatment of episodic migraine is associated with new-onset chronic migraine. Neurology 84: 688–695

    Google Scholar 

  • Matharu M, May A (2008) Functional and structural neuroimaging in trigeminal autonomic cephalalgias. Curr Pain Headache Rep 12: 132–137

    Google Scholar 

  • May A, Straube A, Peikert A et al (2008) Diagnostik und apparative Zusatzuntersuchungen bei Kopfschmerzen. Thieme, Stuttgart

    Google Scholar 

  • Merikangas KR, Rasmussen BK (2000) Migraine comorbidity. In: Oleson J, Tfelt-Hansen P, Welch KMA (eds) The headaches, 2nd ed. Lippincott Williams & Wilkins, Philadelphia

    Google Scholar 

  • Merikangas KR, Angst J, Eaton W, Canino G, Rubio-Stipec M, Wacker H, Wittchen HU, Andrade L, Essau C, Whitaker A, Kraemer H, Robins LN, Kupfer DJ (1996) Comorbidity and boundaries of affective disorders with anxiety disorders and substance misuse: results of an international task force. Br J Psychiatry Suppl (30): 58–67

    Google Scholar 

  • Mersch P (2016) migraeneinformation.de – Ursachen – Psychische Faktoren. http://www.migraeneinformation.de/molmain/main.php?docid=52. Zugegriffen: 17. Februar 2016

  • Moldin SO, Scheftner WA, Rice JP, Nelson E, Knesevich MA, Akiskal H (1993) Association between major depressive disorder and physical illness. Psychol Med 23: 755–761

    Google Scholar 

  • Müller D, Diener HC, Fritsche G, Rabe K (2013) Komorbiditäten der Migräne: praktische Behandlungskonsequenzen. Aktuelle Neurologie 40: 213–223

    Google Scholar 

  • Natoli J, Manack A, Dean B, Butler Q, Turkel C, Stovner L, Lipton R (2010) Global prevalence of chronic migraine: a systematic review. Cephalalgia 30: 599–609

    Google Scholar 

  • Nestoriuc Y, Martin A, Rief W, Andrasik F (2008) Biofeedback treatment for headache disorders: a comprehensive efficacy review. Appl Psychophysiol Biofeedback 33: 125–140

    Google Scholar 

  • Nicholson RA, Gramling SE, Ong JC, Buenaver L (2003) Differences in anger expression between individuals with and without headache after controlling for depression and anxiety. Headache 43: 651–663

    Google Scholar 

  • Noseda R, Burstein R (2013) Migraine pathophysiology: anatomy of the trigeminovascular pathway and associated neurological symptoms, cortical spreading depression, sensitization, and modulation of pain. Pain 154 (Suppl 1): S44–S53

    Google Scholar 

  • Oh K, Chung YK, Kim JM, Chuh MK (2014) Combination of anxiety and depression is associated with an increased headache frequency in migraineurs: a population based study. BMC Neurology 14: 238

    Google Scholar 

  • Palermo TM, Eccleston C, Lewandowski AS, Williams AC, Morley S (2010) Randomized controlled trials of psychological therapies for management of chronic pain in children and adolescents: an updated meta-analytic review. Pain 148: 387–397

    Google Scholar 

  • Panconesi A, Franchini M, Bartolozzi ML, Mugnai S, Guidi L (2013) Alcoholic drinks as triggers in primary headaches. Pain Med 14: 1254–1259

    Google Scholar 

  • Penfield W, McNaughton M (1940) Dural headache and innervation of the dura mater. Arch Neurol Psychiatr 44: 43–75

    Google Scholar 

  • Penzien DB, Andrasik F, Freidenberg BM, HouleTT, Lake AE, Lipchik GL, Holroyd KA, Lipton RB, McCrory DC, Nash JM, Nicholson RA, Powers SW, Rains JC, Wittrock DA (2005) Guidelines for trials of behavioral treatments for recurrent headache: American Headache Society Behavioral Clinical Trials Workgroup. Headache 45 (Suppl 2): S110–S132

    Google Scholar 

  • Peters UH, Schäfer LM, Philipp M (1981) Psychosomatische Therapie der Migräne. Z Psychosom Med 27: 338–346

    Google Scholar 

  • Pietrobon D, Moskowitz MA (2013) Pathophysiology of migraine. Annu Rev Physiol 75: 365–391

    Google Scholar 

  • Pompili M, Di Cosimo D, Innamorati M, Lester D, Tatarelli R, Martelletti P (2009) Psychiatric comorbidity in patients with chronic daily headache and migraine: a selective overview including personality traits and suicide risk. J Headache Pain 10: 283–290

    Google Scholar 

  • Pryse-Phillips WE, Dodick DW, Edmeads JG et al (1998) Guidelines for the nonpharmacological management of migraine in clinical practice. Canadian Headache Society. Can Med Assoc J 159: 47–54

    Google Scholar 

  • Ray BS, Wolff HG (1940) Experimental studies on headache: pain sensitive structures of the head and their significance in headache. Arch Surg 1: 813–856

    Google Scholar 

  • Roberto G, Raschi E, Piccinni C, Conti V, Vignatelli L, D’Alessandro R, De Ponti F, Poluzzi E (2015) Adverse cardiovascular events associated with triptans and ergotamines for treatment of migraine: systematic review of observational studies. Cephalalgia 35: 118–131

    Google Scholar 

  • Rothrock JF (2008) What is migraine? Headache 48: 331

    Google Scholar 

  • Sauro KM, Becker WJ (2009) The stress and migraine interaction. Headache 49: 1378–1386

    Google Scholar 

  • Savi L, Rainero I, Valfrè W, Gentile S, Lo Giudice R, Pinessi L (2002) Food and headache attacks. A comparison of patients with migraine and tension-type headache. Panminerva Med 44: 27–31

    Google Scholar 

  • Schoenen J, Vandersmissen B, Jeangette S, Herroelen L, Vandenheede M, Gérard P, Magis D (2013) Migraine prevention with a supraorbital transcutaneous stimulator: a randomized controlled trial. Neurology 80: 697–704

    Google Scholar 

  • Silberstein SD, Lipton RB, Breslau N (1995) Migraine: association with personality characteristics and psychopathology. Cephalalgia 15: 358–369

    Google Scholar 

  • Spierings ELH, Sorbi M, Maasan GH, Honkoop PC (1997) Psychophysical precedents of migraine in relation to the time of onset of the headache: the migraine time line. Headache 37: 217–220

    Google Scholar 

  • Stankewitz A, May A (2009) The phenomenon of changes in cortical excitability in migraine is not migraine-specific – a unifying thesis. Pain 145: 14–17

    Google Scholar 

  • Stewart WF, Linet MS, Celentano DD (1989) Migraine headaches and panic attacks. Psychosom Med 51: 559–569

    Google Scholar 

  • Stovner LJ, Linde M, Gravdahl GB, Tronvik E, Aamodt AH, Sand T, Hagen KA (2013) Comparative study of candesartan versus propranolol for migraine prophylaxis: A randomised, triple-blind, placebo-controlled, double cross-over study. Cephalalgia 34: 523–532

    Google Scholar 

  • Swendsen JD, Merikangas KR (2000) The comorbidity of depression and substance use disorders. Clin Psychol Rev 20: 173–189

    Google Scholar 

  • Trautmann E, Lackschewitz H, Kröner-Herwig B (2006) Psychological treatment of recurrent headache in children and adolescents – a meta-analysis. Cephalalgia 26: 1411–1426

    Google Scholar 

  • Victor TW, Hu X, Campbell J, White RE, Buse DC, Lipton RB (2010) Association between migraine, anxiety and depression. Cephalalgia 30: 567–575

    Google Scholar 

  • Villeneuve PJ, Szyszkowicz M, Stieb D, Bourque DA (2006) Weather and emergency room visits for migraine headaches in Ottawa, Canada. Headache 46: 64–72

    Google Scholar 

  • Wallasch TM, Chrenko A, Straube A, Felbinger J, Diener HC, Gendolla A, Zwarg T, Wollny M (2009) Ergebnisse aus der Integrierten Versorgung Kopfschmerz – Erfahrungen aus den Kopfschmerzkliniken Berlin, München und Essen. Nervenheilkunde 28: 324–405Weiller C, May A, Limmroth V, Jüptner M, Kaube H, Schayck RV, Coenen HH, Diener HC (1995) Brain stem activation in spontaneous human migraine attacks. Nat Med 1: 658–660

    Google Scholar 

  • Wang Y, Xie J, Yang F, Wu S, Wang H, Zhang X, Liu H, Deng X, Xie W, Yu S (2015) Comorbidity of poor sleep and primary headaches among nursing staff in north China. J Headache Pain 16: 88

    Google Scholar 

  • Wöber C, Brannath W, Schmidt K, Kapitan M, Rudel E, Wessely P, Wöber-Bingöl C; PAMINA Study Group (2007) Prospective analysis of factors related to migraine attacks: the PAMINA study. Cephalalgia 27: 304–314

    Google Scholar 

  • Yilmaz M, Gurger M, Atescelik M, Yildiz M, Gurbuz S (2015) Meteorologic parameters and migraine headache: ED study. Am J Emerg Med 33: 409–413

    Google Scholar 

  • Zebenholzer K, Rudel E, Frantal S, Brannath W, Schmidt K, Wöber-Bingöl C, Wöber C (2011) Migraine and weather: a prospective diary-based analysis. Cephalalgia 31: 391–400

    Google Scholar 

  • Zwart JA, Dyb G, Holmen TL, Stovner LJ, Sand T (2004) The prevalence of migraine and tension-type headaches among adolescents in Norway. Nord-Trøndelag Health Study (Head-HUNT-Youth), a large population-based epidemiological study. Cephalalgia 24: 373–379

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2017 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Fritsche, G., Gaul, C. (2017). Migräne. In: Kröner-Herwig, B., Frettlöh, J., Klinger, R., Nilges, P. (eds) Schmerzpsychotherapie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-50512-0_25

Download citation

  • DOI: https://doi.org/10.1007/978-3-662-50512-0_25

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-50511-3

  • Online ISBN: 978-3-662-50512-0

  • eBook Packages: Medicine (German Language)

Publish with us

Policies and ethics