Skip to main content
SpringerLink
Log in

Infektionen des zentralen Nervensystems und Sepsis

  • Chapter
  • First Online:
Book cover Neurologische Notfälle

  • 5034 Accesses

Zusammenfassung

Im Folgenden wird ein Überblick über die Notfälle bakterielle Meningitis und Herpes-Enzephalitis und anderer seltener infektiologischer Komplikationen im Bereich der neurologischen Intensivmedizin gegeben. Die diagnostischen und therapeutischen Empfehlungen sind an die Leitlinien der Deutsche Gesellschaft für Neurologie (www.dgn.org) angelehnt.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 59.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 74.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Literatur

  • American Thoracic Society; Centers for Disease Control and Prevention; Infectious Diseases Society of America (2005) American Thoracic Society/Centers for Disease Control and Prevention/Infectious Diseases Society of America: controlling tuberculosis in the United States. Am J Respir Crit Care Med 172(9):1169–1227

    Google Scholar 

  • ARISE Investigators; ANZICS clinical trial group, Peake SL, Delaney A. Bailey M, Bellomo R, Cameron PA, Cooper DJ, Higgins AM, Holdgate A, Howe BD, Webb SA, Williams P (2014) Goal-directed resuscitation for patients with early septic shock N Engl J Med 371(16):1496–1506

    Article  CAS  PubMed  Google Scholar 

  • Arlotti M, Grossi P, Pea F, Tomei G, Vullo V, DeRosa FG, DiPerri G, Nicastri E, Lauria FN, Carosi G, Moroni M, Ippolito G, GISIG (Gruppo Italiano di Studio sulle Infezioni Gravi) Working Group on Brain Abscesses (2010) Consensus document on controversial issues for the treatment of infections of the central nervous system: bacterial brain abscesses. Int J Infect Dis 14 Suppl4:S79–92

    Article  Google Scholar 

  • Auburtin M, Wolff M, Charpentier J, Varon E, Le Tulzo Y, Girault C, Mohammedi J, Renard B, Mourvillier B, Bruneel F, Ricard JD, Timsit JF (2006) Detrimental role of delayed administration and penicillin-nonsusceptible strains in adult intensive care unit patients with pneumococcal meningitis: the PNEUMNOREA prospective multicenter study. Crit Care Med 34: 2758–65

    Article  CAS  PubMed  Google Scholar 

  • Brouwer MC, Coutinho JM, van de Beek D (2014) Clinical characteristics and outcome of brain abscess: systemic review and meta-analysis. Neurology 82(9):806

    Article  PubMed  Google Scholar 

  • Brouwer MC, McIntyre P, Prasad K, van de Beek D. Corticosteroids for acute bacterial meningitis. Cochrane Database Syst Rev 2013; Baunbæk-Knudsen G, Sølling M, Farre A, Benfield T, Brandt CT (2015) Improved outcome of bacterial meningitis associated with use of corticosteroid treatment. Infect Dis 11:1–6

    Google Scholar 

  • Brouwer MC, Thwaites GE, Tunkel AR, van de Beek D (2012) Bacterial meningitis 1. Dilemmas in the diagnosis of acute community-acquired bacterial meningitis. Lancet 380: 1684–1692

    Article  PubMed  Google Scholar 

  • De Baker D, Briston P, Devrient J, Madl C, Chochrad D, Aldecoa C, Brasseur A, Defrance P, Gottignies P, Vincent JL; SOAP II Investigators (2010) Comparison of dopamine and norepinephrine an the treatment of shock. N Engl J Med 362(9):779–789

    Article  Google Scholar 

  • Ferrer R, Martin-Loeches I, Phillips G, Osborn TM, Townsend S, Dellinger RP, Artigas A, Schorr C, Levy MM (2014) Empiric antibiotic treatment reduces mortality in servere sepsis and septic shock from the first hour: results from a guideline-based performance improvement program. Crit Care Med 42(8):1749–1755

    Article  CAS  PubMed  Google Scholar 

  • Gaieski DF, Mikkelsen ME, Band RA Pines JM, Massone R, Furia FF, Shofer FS, Goyal M (2010) Impact of time to antibiotics on survival in patients with severe sepsis or septic shock in whom early goal-directed therapy was initiated in the emergency department. Crit Care Med 38:1045–1053

    Article  PubMed  Google Scholar 

  • Glimaker M, Johansson B, Grindborg Ö, Bottai M, Lindquist L, Sjölin J (2015) Adult bacterial meningitis: earlier treatment and improved outcome following guideline revision promoting prompt lumbar puncture. Clin Infec Dis 60: 1162–9

    Article  Google Scholar 

  • Haase N, Ostrowski SR, Wetterslev J, Lange T, Moller MH, Tousi H, Steensen M, Pott F, Soe-Jensen P, Nielsen J, Hjortrup PB, Johanssen PI, Perner A (2015) Thromboelastography in patients with severe sepsis: a propective cohort study. Intensive Care Med 41(1):77–85

    Article  PubMed  Google Scholar 

  • Helweg-Larsen J, Astradsson A, Richhall H, Erdal J, Laursen A, Brennum J (2012) Pyogenic brain abscess, a 15 year survey. BMC Infect Dis 12:332

    Article  PubMed  PubMed Central  Google Scholar 

  • Hjalmarsson A, Blomqvist P, Sköldenberg B (2007) Herpes simplex encephalitis in Sweden, 1990–2001: incidence, morbidity, and mortality. Clin Infect Dis 45(7):875

    Article  PubMed  Google Scholar 

  • Holst LB, Haase N, Wetterslev J, Wernerman J, Guttormsen AB, Karlsson S, Johansson PI, Aneman A, Vang ML, Winding R, Nebrich L, Nibro HL, Rasmussen BS, Lauridsen JR, Nielsen JS, Oldner A, Pettilä V, Cronhjort MB, Andersen LH, Pedersen UG, Reiter N, Wiies J, White JO, Russell L, Thornberg KJ, Hjortrup PB, Müller RG, Möller MH, Steensen M, Rjäder I, Kilsand K, Odeberg-Wernerman S, Sjobo B, Bundgaard H, Thyo MA, Lodahl D, Maerkdahl R, Albeck C, Illum D, Kruse M, Winkel P, Perner A; TRISS Trial Group; Scandinavian Critical Care Trials Group (2014) Lower versus higher hemoglobin threshold for transfusion in septic shock. N Engl J Med 371(15):1381–1391

    Article  PubMed  Google Scholar 

  • Imöhl M, Reinert RR, Tulkens PM, van der Linden M (2014) Penicillin susceptibility breakpoints for Streptococcus pneumoniae and their effect on susceptibility categorisation in Germany (1997–2013). Eur J Clin Microbiol Infect Dis33:2035–40

    Article  Google Scholar 

  • Jung K, Goerdt C, Lange P, Blocher J, Djukic M, Gerber J, Spreer A, Nau R, Otto M, Schmidt H (2011) The use of S100B and Tau protein concentrations in the cerebrospinal fluid for the differential diagnosis of bacterial meningitis: a retrospective analysis. Eur Neurol 66: 128–32

    Article  CAS  PubMed  Google Scholar 

  • Kasanmoentalib ES, Brouwer MC, van der Ende A, van de Beek D (2010) Hydrocephalus in adults with community-acquired bacterial meningitis. Neurology 75(10): 918–923

    Article  PubMed  Google Scholar 

  • Kaukonen KM, Bailey M, Suzuki S, Pilcher D, Bellomo R (2014) Mortality related to servere sepsis and septic shock among critically ill patients in Australia and New Zealand, 2000–2012. JAMA 311(13):1308

    Article  CAS  PubMed  Google Scholar 

  • Leligdowicz A, Dodek PM, Norena M, Wong H, Kumar A, Kumar A (2014) Co-operative antimicrobial therapy of septic shock database research group. Association between source of infection and hospital mortality in patients who have septic shock. Am J Respir Crit Care Med 189(10):1204

    Article  PubMed  Google Scholar 

  • Lepur D, Barsic B (2007) Community-acquired bacterial meningitis in adults: antibiotic timing in disease course and outcome. Infection 35(4): 225–231

    Article  CAS  PubMed  Google Scholar 

  • Nau R, Djukic M, Spreer A, Eiffert H (2013) Bacterial meningitis: new therapeutic approaches. Expert Rev Anti Infect Ther 11(10):1079–95

    Article  CAS  PubMed  Google Scholar 

  • Nau R, Soto A, Brück W (1999) Apoptosis of neurons in the dentate gyrus in humans suffering from bacterial meningitis. J Neuropathol Exp Neurol 58:265–74

    Article  CAS  PubMed  Google Scholar 

  • Neyra JA, Canepa-Escaro F, Li X, Manllo J, Adams-Huet B, Yee J, Yessayan L. Acute Kindney Injury in Critical Illness Study Group (2015) Association of hyperchloremia with hospital mortality in critically ill septic patients. Crit Care Med 43(9):1938–1944

    Article  PubMed  PubMed Central  Google Scholar 

  • ProCESS Investigators, Yealy DM, Kellum JA, Huang DT, Barnato AE, Weissfeld LA, Pike F, Terndrup T, Wang HE, Hou PC, LoVecchio F, Filbin MR, Shapiro NI, Angus DC (2014) A randomized trial of protocol-based care for early septic shock. N Engl J Med 370(18):1683–1693

    Article  CAS  PubMed  Google Scholar 

  • Ratnaike TE, Das S, Gregson BA, Mendelow AD (2011) A review of brain abscess surgical treatment – 78 years: aspiration versus excision. World Neurosurg 76(5):431–436

    Article  PubMed  Google Scholar 

  • Sterling SA, Miller WR, Pryor J, Puskarich MA, Jones AE (2015) The Impact of Timing of Antibiotics on Outcomes in Severe Sepsis and Septic Shock: A Systematic Review and Meta-Analysis. Crit Care Med 43(9):1907–15

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Thigpen MC, Whitney CG, Messonnier NE, Zell ER, Lynfield R, Hadler JL, Harrison LH, Farley MM, Reingold A, Bennett NM, Craig AS, Schaffner W, Thomas A, Lewis MM, Scallan E, Schuchat A, Emerging Infections Programs Network (2011) Bacterial meningitis in the United States, 1998–2007. N Engl J Med 364(21):2016

    Article  CAS  PubMed  Google Scholar 

  • Thwaites GE, van Toorn R, Schoeman J (2013) Tuberculous meningitis: more questions, still too few answers. Lancet Neurol 12(10):999–1010

    Article  CAS  PubMed  Google Scholar 

  • van de Beek D, de Gans J, Spanjaard L, Weisfelt M, Reitsma JB, Vermeulen M (2004) Clinical features and prognostic factors in adults with bacterial meningitis. N Engl J Med 351(18):1849

    Article  CAS  PubMed  Google Scholar 

  • Wacker C, Prkno A, Brunkhorst FM, SchlattmannP (2013) Procalcitonin as a diagnostic marker for sepsis: a systematic review and meta-analysis. Lancet Infect Dis13(5):426–35

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Klinik für Neurologie, RWTH Aachen, Pauwelsstr. 30, 52074, Aachen, Deutschland

    S. Tauber

Authors
  1. S. Tauber
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Klinik für Neurologie, RWTH Aachen , Aachen, Germany

    Jens Litmathe

Rights and permissions

Reprints and permissions

Copyright information

© 2016 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Tauber, S. (2016). Infektionen des zentralen Nervensystems und Sepsis. In: Litmathe, J. (eds) Neurologische Notfälle. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-49775-3_4

Download citation

  • DOI: https://doi.org/10.1007/978-3-662-49775-3_4

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-49774-6

  • Online ISBN: 978-3-662-49775-3

  • eBook Packages: Medicine (German Language)

Publish with us

Policies and ethics

Search

Navigation