Zusammenfassung
Im Folgenden werden praxisrelevante Inhalte als Grundlagen für eine erfolgreiche prä- und intrahospitale Schlaganfallrettungskette dargestellt. Ziel einer zeitoptimierten Patientenversorgung beim ischämischen Schlaganfall ist die Beantwortung der Frage, ob für den individuellen Fall die Anwendung von zerebralen Reperfusionsmaßnahmen möglich ist. Die Indikationsstellung und Durchführung dieser Maßnahmen obliegt vaskulären Neurologen und interventionellen Neuroradiologen und sollte in Kliniken mit zertifizierten Schlaganfalleinheiten durchgeführt werden. Für die fachspezifischen Inhalte wird auf die Leitlinien der jeweiligen deutschen Fachgesellschaften und der deutschen Schlaganfall-Gesellschaft verwiesen (www.dgn.org, www.dgnr.org, www.dsg-info.de).
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Literatur
Publikationen
Adams, H. P. et al. Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment. Stroke 24, 35–41 (1993)
Albers, G. W. et al. Transient ischemic attack––proposal for a new definition. N. Engl. J. Med. 347, 1713–1716 (2002)
Aries, M. J. H., Elting, J. W., De Keyser, J., Kremer, B. P. H. & Vroomen, P. C. A. J. Cerebral Autoregulation in Stroke A Review of Transcranial Doppler Studies. Stroke 41, 2697–2704 (2010)
Atkins, E. R., Brodie, F. G., Rafelt, S. E., Panerai, R. B. & Robinson, T. G. Dynamic Cerebral Autoregulation Is Compromised Acutely following Mild Ischaemic Stroke but Not Transient Ischaemic Attack. Cerebrovasc Dis 29, 228–235 (2010)
Barber, P. A., Demchuk, A. M., Zhang, J. & Buchan, A. M. Validity and reliability of a quantitative computed tomography score in predicting outcome of hyperacute stroke before thrombolytic therapy. The Lancet 355, 1670–1674 (2000)
Baron, J. C. Mapping the ischaemic penumbra with PET: implications for acute stroke treatment. Cerebrovasc Dis 9, 193–201 (1999)
Berkhemer, O. A. et al. A Randomized Trial of Intraarterial Treatment for Acute Ischemic Stroke. N. Engl. J. Med. 141217070022009 (2014). doi:10.1056/NEJMoa1411587
Bouvin, V. Consensus statementon mechanical thrombectomy in acute ischemic stroke. 1–14 (2015)
Broderick, J. et al. Guidelines for the management of spontaneous intracerebral hemorrhage in adults: 2007 update: a guideline from the American Heart Association/American Stroke Association Stroke Council, High Blood Pressure Research Council, and the Quality of Care and Outcomes in Research Interdisciplinary Working Group. Stroke 38, 2001–2023 (2007)
Busse, O. et al. Interdisciplinary neurovascular network. Nervenarzt 84, 1228–1232 (2013)
Campbell, B. C. V. et al. Endovascular Therapy for Ischemic Stroke with Perfusion-Imaging Selection. N. Engl. J. Med. 150211090353006 (2015). doi:10.1056/NEJMoa1414792
Easton, J. D. et al. Definition and evaluation of transient ischemic attack: a scientific statement for healthcare professionals from the American Heart Association/American Stroke Association Stroke Council; Council on Cardiovascular Surgery and Anesthesia; Council on Cardiovascular Radiology and Intervention; Council on Cardiovascular Nursing; and the Interdisciplinary Council on Peripheral Vascular Disease. The American Academy of Neurology affirms the value of this statement as an educational tool for neurologists. Stroke 40, 2276–2293 (2009)
Edlow JA, Selim MH. Atypical presentations of acute cerebrovascular syndromes. The Lancet Neurology 10, 550–560 (2011)
Feigin VL et al. Global and regional burden of stroke during 1990–2010: findings from the Global Burden of Disease Study 2010. The Lancet 383, 245–255 (2014)
Goyal, M. et al. Randomized Assessment of Rapid Endovascular Treatment of Ischemic Stroke. N. Engl. J. Med. 150211090353006 (2015). doi:10.1056/NEJMoa1414905
Hacke, W. et al. Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke. N. Engl. J. Med. 359, 1317–1329 (2008)
Heldner, M. R. et al. National Institutes of Health Stroke Scale Score and Vessel Occlusion in 2152 Patients With Acute Ischemic Stroke. Stroke 44, 1153–1157 (2013)
Heuschmann, P. et al. Schlaganfallhäufigkeit und Versorgung von Schlaganfallpatienten in Deutschland. Akt Neurol 37, 333–340 (2010)
Hurford, R. et al. Incidence, predictors and clinical characteristics of orolingual angio-oedema complicating thrombolysis with tissue plasminogen activator for ischaemic stroke. Journal of Neurology, Neurosurgery & Psychiatry 86, 520–523 (2015)
Johnston, S. C. et al. Validation and refinement of scores to predict very early stroke risk after transient ischaemic attack. The Lancet 369, 283–292 (2007)
Jovin, T. G. et al. Thrombectomy within 8 Hours after Symptom Onset in Ischemic Stroke. N. Engl. J. Med. 150417035025009 (2015). doi:10.1056/NEJMoa1503780
Kasner, S. E. Clinical interpretation and use of stroke scales. The Lancet Neurology 5, 603–612 (2006)
Lees, K. R. et al. Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials. The Lancet 375, 1695–1703 (2010)
Li, L. et al. Incidence, outcome, risk factors, and long-term prognosis of cryptogenic transient ischaemic attack and ischaemic stroke: a population-based study. The Lancet Neurology 14, 903–913 (2015)
Lip, G. Y. H., Frison, L., Halperin, J. L. & Lane, D. A. Identifying Patients at High Risk for Stroke Despite Anticoagulation A Comparison of Contemporary Stroke Risk Stratification Schemes in an Anticoagulated Atrial Fibrillation Cohort. Stroke 41, 2731–2738 (2010b)
Lip, G. Y. H., Nieuwlaat, R., Pisters, R., Lane, D. A. & Crijns, H. J. G. M. Refining Clinical Risk Stratification for Predicting Stroke and Thromboembolism in Atrial Fibrillation Using a Novel Risk Factor-Based Approach The Euro Heart Survey on Atrial Fibrillation. Chest 137, 263–272 (2010a)
Lozano, R., Naghavi, M., Foreman, K., Lim, S. & Shibuya, K. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010. The Lancet (2013)
Meretoja, A. et al. Helsinki model cut stroke thrombolysis delays to 25 minutes in Melbourne in only 4 months. Neurology 81, 1071–1076 (2013)
Meretoja, A. et al. Reducing in-hospital delay to 20 minutes in stroke thrombolysis. Neurology 79, 306–313 (2012)
Murray, C., Vos, T., Lozano, R., Naghavi, M. & Flaxman, A. D. Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010. The Lancet (2013)
Nabavi, D. G. et al. [Revised certification criteria for regional and national stroke units in Germany]. Nervenarzt 86, 978–988 (2015)
Nadarajan, V., Perry, R. J., Johnson, J. & Werring, D. J. Transient ischaemic attacks: mimics and chameleons. Pract Neurol 14, 23–31 (2014)
Nguyen, P. L. & Chang, J. J. Stroke Mimics and Acute Stroke Evaluation: Clinical Differentiation and Complications after Intravenous Tissue Plasminogen Activator. J Emerg Med 49, 244–252 (2015)
Rha, J. H. & Saver, J. L. The Impact of Recanalization on Ischemic Stroke Outcome: A Meta-Analysis. Stroke 38, 967–973 (2007)
Saver, J. L. & Levine, S. R. Alteplase for ischaemic stroke—much sooner is much better. The Lancet 375, 1667–1668 (2010)
Saver, J. L. et al. Stent-Retriever Thrombectomy after Intravenous t-PA vs. t-PA Alone in Stroke. N. Engl. J. Med. 150417023017004 (2015). doi:10.1056/NEJMoa1415061
Saver, J. L. et al. Time to treatment with intravenous tissue plasminogen activator and outcome from acute ischemic stroke. JAMA 309, 2480–2488 (2013)
Saver, J. L. Time is brain––quantified. Stroke 37, 263–266 (2006)
Schneider, K., Heise, M., Heuschmann, P. & Berger, K. Situation of life and care in patients with a stroke. Nervenheilkunde 28, 114–+ (2009)
Schwamm, L. H. Acute Stroke: Shifting From Informed Consent to Informed Refusal of Intravenous Tissue-Type Plasminogen Activator. Circ Cardiovasc Qual Outcomes 8, S69–72 (2015)
Sheth, S. A. et al. Time to endovascular reperfusion and degree of disability in acute stroke. Ann Neurol. 78, 584–593 (2015)
Spiotta, A. M. et al. Evolution of thrombectomy approaches and devices for acute stroke: a technical review. Journal of NeuroInterventional Surgery (2014). doi:10.1136/neurintsurg-2013-011022
The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. Tissue plasminogen activator for acute ischemic stroke. N. Engl. J. Med. 333, 1581–1587 (1995)
Tong, D. Are all IV thrombolysis exclusion criteria necessary?: Being SMART about evidence-based medicine. Neurology 76, 1780–1781 (2011)
Tong, D. C. Avoiding Thrombolysis In Patients With Mild Stroke: Is It SMART? Stroke 43, 625–626 (2012)
Tsivgoulis, G. et al. Safety of Intravenous Thrombolysis in Stroke Mimics. (2015)
Unal, B., Critchley, J. A. & Capewell, S. Explaining the Decline in Coronary Heart Disease Mortality in England and Wales Between 1981 and 2000. Circulation (2004)
Walter, S. et al. Diagnosis and treatment of patients with stroke in a mobile stroke unit versus in hospital: a randomised controlled trial. The Lancet Neurology 11, 397–404 (2012)
Ward, A., Payne, K. A., Caro, J. J., Heuschmann, P. U. & Kolominsky-Rabas, P. L. Care needs and economic consequences after acute ischemic stroke: the Erlangen Stroke Project. Eur J Neurol 12, 264–267 (2005)
Wardlaw, J. M., Murray, V., Berge, E. & del Zoppo, G. J. Thrombolysis for acute ischaemic stroke. Cochrane Database Syst Rev 7, CD000213 (2014)
Zaidat, O. O. et al. Recommendations on Angiographic Revascularization Grading Standards for Acute Ischemic Stroke: A Consensus Statement. Stroke 44, 2650–2663 (2013)
Links
Arbeitstagung NeuroIntensivMedizin: http://www.anim.de
Deutsche Gesellschaft für NeuroIntensiv- und Notfallmedizin: http://www.dgni.de
Deutsche Gesellschaft für Neurologie: http://www.dgn.org
Deutsche Gesellschaft für Neuroradiologie: http://www.dgnr.org
Deutsche Gesellschaft für Neurorehabilitation e.V.: http://www.dgnr.de
Deutsche Schlaganfallgesellschaft: http://www.dsg-info.de
Kompetenznetz Schlaganfall: http://www.schlaganfallnetz.de
NIHSS Training und Zertifizierung: https://secure.trainingcampus.net/uas/modules/trees/windex.aspx?rx=nihss-english.trainingcampus.net
Stiftung Deutsche Schlaganfall-Hilfe: http://www.schlaganfall-hilfe.de
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Reich, A., Nikoubashman, O. (2016). Ischämischer Schlaganfall (zerebrale Ischämie). In: Litmathe, J. (eds) Neurologische Notfälle. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-49775-3_1
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