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Interactions Between Periodontal Disease and Chronic Kidney Diseases

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A Clinician's Guide to Systemic Effects of Periodontal Diseases

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Abstract

An increasing number of patients with chronic kidney disease (CKD) including those with end-stage renal disease (ESRD) on renal replacement therapy present each year for dental care. This increase is due, in part, to the rising prevalence of type 2 diabetes and the aging population demographics of industrialized nations. However, advances in renal replacement technologies have also greatly increased the life expectancies for ESRD patients thereby increasing the size of this patient population. In addition, not only will the dental profession be asked to care for an increasing number of CKD patients, but recent studies suggest that periodontitis may affect the medical management of the CKD patient. Adverse outcomes including mortality have been associated with increased systemic inflammation in both the CKD and the general population making means to decease systemic inflammation an emerging medical concern [1, 2]. For patients receiving hemodialysis maintenance therapy, for example, increased systemic inflammation has been closely associated with atherosclerotic complications including myocardial infarction and stroke, which are among the most frequent causes of mortality in this patient population [3].

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Author information

Authors and Affiliations

  1. Department of Basic Sciences and Craniofacial Biology, New York University College of Dentistry, New York, NY, USA

    Ronald G. Craig DMD, PhD

  2. Department of Periodontology and Implant Dentistry, New York University College of Dentistry, New York, NY, USA

    Ronald G. Craig DMD, PhD

  3. Private Corporation, Renal Research Institute, New York, NY, USA

    Peter Kotanko MD

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  1. Ronald G. Craig DMD, PhD
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  2. Peter Kotanko MD
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Correspondence to Ronald G. Craig DMD, PhD .

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Editors and Affiliations

  1. Basic Sciences and Craniofacial Biology, New York University College of Dentistry, New York, New York, USA

    Ronald G. Craig

  2. New York University College of Dent, New York, New York, USA

    Angela R. Kamer

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Craig, R.G., Kotanko, P. (2016). Interactions Between Periodontal Disease and Chronic Kidney Diseases. In: Craig, R., Kamer, A. (eds) A Clinician's Guide to Systemic Effects of Periodontal Diseases. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-49699-2_5

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  • DOI: https://doi.org/10.1007/978-3-662-49699-2_5

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