Skip to main content
SpringerLink
Log in

Humane Herpesviren

  • Chapter
  • First Online:
Braun-Falco’s Dermatologie, Venerologie und Allergologie

Part of the book series: Springer Reference Medizin ((SRM))

  • 1475 Accesses

Zusammenfassung

Jedes der derzeit bekannten acht Herpesviren kann mit Hauterkrankungen assoziiert sein, je nach Typ sind bestimmte Läsionen typisch. Alle Herpesviren bleiben nach der akuten Infektion trotz zellulärer Immunantwort im Wirt (Latenz) und sind reaktivierbar. Die möglichen Erkrankungen variieren stark; Art und Ausprägung der Krankheit sind abhängig vom Alter und Immunstatus des Patienten und davon, ob es sich um eine Primär- oder Sekundärinfektion handelt. Triggerfaktoren wie Fieber, Sonnenlicht, Trauma oder Stress sind mögliche Auslöser für Rezidive, was vor allem für das Herpes-simplex-Virus gilt. Zur Therapie stehen verschiedene Virostatika zur Verfügung, in jüngster Zeit sind weitere Wirkstoffe entwickelt worden.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 369.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Literatur

  • Agut H, Bonnafous P, Gautheret-Dejean A (2015) Laboratory and clinical aspects of human herpesvirus 6 infections. Clin Microbiol Rev 28:313–335

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Ahn KH, Park YJ, Hong SC, Lee EH, Lee JS, Oh MJ, Kim HJ (2016) Congenital varicella syndrome: a systematic review. J Obstet Gynaecol 36:563–566

    Article  PubMed  Google Scholar 

  • Aoki FY, Tyring S, Diaz-Mitoma F et al (2006) Single-day, patient-initiated famciclovir therapy for recurrent genital herpes: a randomized, double-blind, placebo-controlled trial. Clin Infect Dis 42:8–13

    Article  CAS  PubMed  Google Scholar 

  • Benedetti JK, Zeh J, Corey L (1999) Clinical reactivation of genital herpes simplex virus infection decreases in frequency over time. Ann Intern Med 131:14–20

    Article  CAS  PubMed  Google Scholar 

  • Birkmann A, Zimmermann H (2016) HSV antivirals – current and future treatment options. Curr Opin Virol 18:9–13

    Article  CAS  PubMed  Google Scholar 

  • Brown ZA, Selke S, Zeh J et al (1997) The acquisition of herpes simplex virus during pregnancy. N Engl J Med 337:509–515

    Article  CAS  PubMed  Google Scholar 

  • Cernik C, Gallina K, Brodell RT (2008) The treatment of herpes simplex infections: an evidence-based review. Arch Intern Med 168:1137–1144

    Article  CAS  PubMed  Google Scholar 

  • Chi CC, Wang SH, Delamere FM et al (2015) Interventions for prevention of herpes simplex labialis (cold sores on the lips). Cochrane Database Syst Rev:CD010095

    Google Scholar 

  • Corey L, Wald A, Patel R, Sacks SL et al (2004) Once-daily valacyclovir to reduce the risk of transmission of genital herpes. N Engl J Med 350:11–20

    Article  CAS  PubMed  Google Scholar 

  • Drago F, Broccolo F, Rebora A (2009) Pityriasis rosea: an update with a critical appraisal of its possible herpesviral etiology. J Am Acad Dermatol 61:303–318

    Article  PubMed  Google Scholar 

  • Dworkin RH, Johnson RW, Breuer J et al (2007) Recommendations for the management of herpes zoster. Clin Infect Dis 44(Suppl 1):S1–S26

    Article  CAS  PubMed  Google Scholar 

  • Ebell MH, Call M, Shinholser J, Gardner J (2016) Does this patient have infectious mononucleosis?: the rational clinical examination systematic review. JAMA 315:1502–1509

    Article  CAS  PubMed  Google Scholar 

  • Fatahzadeh M, Schwartz RA (2007) Human herpes simplex virus infections: epidemiology, pathogenesis, symptomatology, diagnosis, and management. J Am Acad Dermatol 57:737–763

    Article  PubMed  Google Scholar 

  • Gnann JW Jr, Whitley RJ (2016) Genital herpes. N Engl J Med 375:666–674

    Article  PubMed  Google Scholar 

  • Gross G, Schöfer H, Wassilew S et al (2003) Herpes zoster guideline of the German Dermatology Society (DDG). J Clin Virol 26:277–289

    Article  CAS  PubMed  Google Scholar 

  • Gupta R, Warren T, Wald A (2007) Genital herpes. Lancet 370:2127–2137

    Article  PubMed  Google Scholar 

  • Heininger U, Seward JF (2006) Varicella. Lancet 368:1365–1376

    Article  PubMed  Google Scholar 

  • Hocqueloux L, Guinard J, Buret J et al (2013) Do penicillins really increase the frequency of a rash when given during Epstein-Barr Virus primary infection? Clin Infect Dis 57:1661–1662

    Article  CAS  PubMed  Google Scholar 

  • Hofstetter AM, Rosenthal SL, Stanberry LR (2014) Current thinking on genital herpes. Curr Opin Infect Dis 27:75–83

    Article  CAS  PubMed  Google Scholar 

  • Hollier LM, Wendel GD (2008) Third trimester antiviral prophylaxis for preventing maternal genital herpes simplex virus (HSV) recurrences and neonatal infection. Cochrane Database Syst Rev:CD004946

    Google Scholar 

  • Hurt C, Tammaro D (2007) Diagnostic evaluation of mononucleosis-like illnesses. Am J Med 120:911–918

    Article  PubMed  Google Scholar 

  • Hyde TB, Schmid DS, Cannon MJ (2010) Cytomegalovirus seroconversion rates and risk factors: implications for congenital CMV. Rev Med Virol 20:311–326

    Article  PubMed  Google Scholar 

  • Itin PH, Battegay M (2009) Haut- und Schleimhautinfektionen bei Immunsuppression. Internist (Berl) 50:150–159

    Article  CAS  Google Scholar 

  • Johnston C, Corey L (2016) Current concepts for genital herpes simplex virus infection: diagnostics and pathogenesis of genital tract shedding. Clin Microbiol Rev 29:149–161

    Article  PubMed Central  Google Scholar 

  • Kempf W, Lautenschlager S (2001) Infektionen mit dem Varizella-zoster-Virus. Hautarzt 52:359–376

    Article  CAS  PubMed  Google Scholar 

  • Kimberlin DW (2007) Herpes simplex virus infections of the newborn. Semin Perinatol 31:19–25

    Article  PubMed  Google Scholar 

  • Kimberlin DW, Whitley RJ (2007) Varicella-zoster vaccine for the prevention of herpes zoster. N Engl J Med 356:1338–1343

    Article  CAS  PubMed  Google Scholar 

  • Lal H, Cunningham AL, Godeaux O et al (2015) Efficacy of an adjuvanted herpes zoster subunit vaccine in older adults. N Engl J Med 372:2087–2096

    Article  PubMed  Google Scholar 

  • Langenberg AG, Corey L, Ashley RL et al (1999) A prospective study of new infections with herpes simplex virus type 1 and type 2. Chiron HSV Vaccine Study Group. N Engl J Med 341:1432–1438

    Article  CAS  PubMed  Google Scholar 

  • Lautenschlager S, Eichmann A (2001) The heterogeneous clinical spectrum of genital herpes. Dermatology 202:211–219

    Article  CAS  PubMed  Google Scholar 

  • Lautenschlager S, Eichmann A (2002) Urethritis: an underestimated clinical variant of genital herpes in men? J Am Acad Dermatol 46:307–308

    Article  PubMed  Google Scholar 

  • Lautenschlager S, Kempf W (2000) Herpes genitalis. Hautarzt 51:964–980

    Article  CAS  PubMed  Google Scholar 

  • Lebrun-Vignes B, Bouzamondo A, Dupuy A et al (2007) A meta-analysis to assess the efficacy of oral antiviral treatment to prevent genital herpes outbreaks. J Am Acad Dermatol 57:238–246

    Article  PubMed  Google Scholar 

  • Looker KJ, Magaret AS, May MT et al (2015) Global and regional estimates of prevalent and incident herpes simplex virus type 1 infections in 2012. PLoS One 10, e0140765

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Martin ET, Krantz E, Gottlieb SL et al (2009) A pooled analysis of the effect of condoms in preventing HSV-2 acquisition. Arch Intern Med 169:1233–1240

    Article  PubMed  PubMed Central  Google Scholar 

  • Oxman MN, Levin MJ, Johnson GR, Schmader KE et al (2005) A vaccine to prevent herpes zoster and postherpetic neuralgia in older adults. N Engl J Med 352:2271–2284

    Article  CAS  PubMed  Google Scholar 

  • Patel R, Stanberry L, Whitley RJ (2007) Review of recent HSV recurrent-infection treatment studies. Herpes 14:23–26

    PubMed  Google Scholar 

  • Ryder N, Jin F, McNulty AM et al (2009) Increasing role of herpes simplex virus type 1 in first-episode anogenital herpes in heterosexual women and younger men who have sex with men, 1992-2006. Sex Transm Infect 85:416–419

    Article  CAS  PubMed  Google Scholar 

  • Sampath A, Maduro G, Schillinger JA (2016) Infant deaths due to herpes simplex virus, congenital syphilis, and HIV in New York City. Pediatrics 137:4. https://doi.org/10.1542/peds.2015-2387

    Article  PubMed  Google Scholar 

  • Sauerbrei A (2016) Optimal management of genital herpes: current perspectives. Infect Drug Resist 9:129–141

    Article  PubMed  PubMed Central  Google Scholar 

  • Schwartz RA, Micali G, Nasca MR, Scuderi L (2008) Kaposi sarcoma: a continuing conundrum. J Am Acad Dermatol 59:179–206

    Article  PubMed  Google Scholar 

  • Spruance S, Aoki FY, Tyring S et al (2007) Short-course therapy for recurrent genital herpes and herpes labialis. J Fam Pract 56:30–36

    PubMed  Google Scholar 

  • Weinberg JM (2007) Herpes zoster: epidemiology, natural history, and common complications. J Am Acad Dermatol 57:S130–S135

    Article  PubMed  Google Scholar 

  • Whitley RJ, Volpi A, McKendrick M et al (2010) Management of herpes zoster and post-herpetic neuralgia now and in the future. J Clin Virol 48(Suppl 1):S20–S28

    Article  CAS  PubMed  Google Scholar 

  • Wollenberg A, Zoch C, Wetzel S et al (2003) Predisposing factors and clinical features of eczema herpeticum: a retrospective analysis of 100 cases. J Am Acad Dermatol 49:198–205

    Article  PubMed  Google Scholar 

  • Wolz MM, Sciallis GF, Pittelkow MR (2012) Human herpesviruses 6, 7, and 8 from a dermatologic perspective. Mayo Clin Proc 87:1004–1014

    Article  PubMed  PubMed Central  Google Scholar 

Erstbeschreiber

  • Fessler A, Feyrter F (1926) Untersuchungen über das Aphthoid-Pospischill. Z Kinderheilk 41:489–498

    Article  Google Scholar 

  • Heubner O (1911) Lehrbuch der Kinderheilkunde. Barth, Leipzig, S 445

    Google Scholar 

  • Hunt JR (1907) On herpetic inflammations of the geniculate ganglion. A new syndrome and its complications. J Nerv Ment Dis 34:73–99

    Article  Google Scholar 

  • Juliusberg F (1898) Pustulosis acuta varioliformis. Arch Dermatol Syph 49:21–28

    Article  Google Scholar 

  • Kaposi M (1887) Pathologie und Therapie der Hautkrankheiten. Urban & Schwarzenberg, Wien, S 483

    Google Scholar 

  • Lipschütz BC (1918) Über Ulcus vulvae acutum. Wien Klin Wochenschr 31:461–464

    Google Scholar 

  • Pfeiffer E (1889) Drüsenfieber. Jahrbuch Kinderheilkd Physische Erzieh 29:257–294

    Google Scholar 

  • Pospischill D (1921) Über Klinik und Epidemiologie der Pertussis. Karger, Berlin

    Google Scholar 

  • Reye RDK, Morgan G, Baral J (1963) Encephalopathy and fatty degeneration of the vicera: a disease entity in childhood. Lancet 2:749–752

    Article  CAS  PubMed  Google Scholar 

  • Tzanck A (1947) Le cyto-diagnostic immediate en dermatologie. Ann Dermatol Venereol 7:68–70

    Google Scholar 

  • Wolf R, Brenner S, Ruocco V et al (1995) Isotopic response. Int J Dermatol 34:341–348

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Chefarzt Dermatologisches Ambulatorium, Stadtspital Triemli, Hermann Greulich Str. 70, 8004, Zürich, Schweiz

    Stephan Lautenschlager

Authors
  1. Stephan Lautenschlager
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Stephan Lautenschlager .

Editor information

Editors and Affiliations

  1. Klinik und Poliklinik für Dermatologie und Allergologie, Universitätsklinikum München, München, Germany

    Gerd Plewig

  2. Klinik und Poliklinik für Dermatologie und Allergologie, Universitätsklinikum München, München, Germany

    Thomas Ruzicka

  3. Klinik für Dermatologie, Venerologie und Allergologie, J.W.Goethe-Universität, Frankfurt, Germany

    Roland Kaufmann

  4. Klinik für Dermatologie und Allergologie, Universitätsklinikum Marburg, Marburg, Germany

    Michael Hertl

Section Editor information

  1. Zentrum für Hautkrankheiten, Deutschhausstraße 9, 35037, Marburg, Germany

    Michael Hertl

Rights and permissions

Reprints and permissions

Copyright information

© 2018 Springer-Verlag GmbH Deutschland, ein Teil von Springer Nature

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Lautenschlager, S. (2018). Humane Herpesviren. In: Plewig, G., Ruzicka, T., Kaufmann, R., Hertl, M. (eds) Braun-Falco’s Dermatologie, Venerologie und Allergologie. Springer Reference Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-49544-5_9

Download citation

  • DOI: https://doi.org/10.1007/978-3-662-49544-5_9

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-49543-8

  • Online ISBN: 978-3-662-49544-5

  • eBook Packages: Medicine (German Language)

Publish with us

Policies and ethics

Search

Navigation