Abstract
The author studied the safety and efficacy of articaine in tumescent local anesthesia even with use of high quantities. He found that articaine exerts high anesthetic potency and low toxicity. There were no neurotoxic or cardiac side effects due to articaine that were observed during or after the treatment. Articaine may be the choice local anesthetic to use in liposuction.
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References
Danford N. The genetic toxicology of ortho-toluidine. Mutat Res. 1991;3258(3):207–36.
Fatemi A. Liposucktion in TLA—ein risikofreies verfahren? Hauptsache Haut. 2000;4:42–3.
Klein JA. Tumescent technique for regional anesthesia permits lidocaine doses of 35 mg/kg for liposuction surgery. J Dermatol Surg Oncol. 1990;16(3):248–63.
Klein JA. The tumescent technique for liposuction surgery. Am J Cosmet Surg. 1987;4(4):263–7.
Leuschner J, Leblanc D. Studies on the toxicological profile of the local anesthetic articaine. Arzneimittelforschung. 1999;49(2):126–32.
McCaughey W. Adverse effects of local anesthetics. Drug Saf. 1992;7(3):178–89.
Tucker GT. Local anesthetic drugs – mode of action and pharmacokinetics. Anaesthesia. 1990;38:983–1010.
Moller R, Covino BG. Cardiac electrophysiologic properties of bupivacaine and lidocaine compared with those of ropivacaine. Anesthesiology. 1990;72(2):322–9.
Oertel R, Ebert U, Rahn R, Kirch W. The effect of age on pharmacokinetics of the local anesthetic drug articaine. Reg Anesth Pain Med. 1999;21(6):524–8.
Oertel R, Rahn R, Kirch W. Clinical pharmacokinetics of articaine. Clin Pharmacokinet. 1997;33(6):417–25.
Rahn R, Oertel R. Pharmacokinetics of articaine following submucosal injection. Deutsches Zahnärzteblatt. 2000;7:109–14.
Rao RB, Ely SF, Hoffmann RS. Deaths related to liposuction. N Engl J Med. 1999;340(19):1471–5.
Sattler G, Rapprich S, Hagedorn M. Tumeszenz-Lokala-nästhesie. Untersuchung zur pharmakokinetik von prilocain. Z Hautkr. 1997;7:522–5.
Spiegel DA, Dexter F, Warner DS. Central nervous system toxicity of local anesthetic mixtures in the rat. Anesth Analg. 1992;75(6):922–8.
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Fatemi, A. (2016). Tumescent Local Anesthesia with Articaine. In: Shiffman, M., Di Giuseppe, A. (eds) Liposuction. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-48903-1_4
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DOI: https://doi.org/10.1007/978-3-662-48903-1_4
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