Advertisement

Geriatrische Syndrome

  • Heinrich Burkhardt
Chapter
Part of the Springer Reference Medizin book series (SRM)

Zusammenfassung

Geriatrische Syndrome beschreiben häufig entscheidend die klinische Situation bei älteren Patienten. Allen voran sind hier Störungen der lokomotorischen Kompetenz und kognitive Veränderungen zu nennen. Dahinter stehen direkt durch Alterung bedingte Phänomene wie die Sarkopenie aber auch Erkrankungen mit klarem Bezug zu höherem Lebensalter wie z. B. die Demenzerkrankungen. In der Behandlung älterer Patienten mit Tumorerkrankung spielen die geriatrischen Syndrome eine wichtige Rolle, da sie Therapie und Krankheitsbewältigung in allen Phasen beeinflussen können. Dabei finden sich viele wechselseitige Bezüge auch zu häufig mit Tumorerkrankungen assoziierten Problemen wie Fatigue und Kachexie. Das Kapitel gibt einen Überblick über die wesentlichen geriatrischen Syndrome und die sich daraus ergebenden Aspekte im onkologischen Kontext.

Literatur

  1. Bellino S, Bogetto F, Vaschetto P, Ziero S, Ravizza L (2000) Recognition and treatment of dysthymia in elderly patients. Drugs Aging 16:107–121CrossRefPubMedGoogle Scholar
  2. Burkhardt H, Wehling M, Gladisch R (2007) Prävention unerwünschter Arzneimittelwirkungen bei älteren Patienten. Z Gerontol Geriatr 40:241–255CrossRefPubMedGoogle Scholar
  3. Charlson FJ, Ferrari AJ, Flaxman AD, Whiteford HA (2013) The epidemiological modelling of dysthymia: application for the global burden of disease study 2010. J Affect Disord 151:111–120CrossRefPubMedGoogle Scholar
  4. Cruz-Jentoft AJ, Baeyens JP, Bauer JM, Boirie Y, Cederholm T, Landi F, Martin FC, Michel JP, Rolland Y, Schneider SM, Topinková E, Vandewoude M, Zamboni M, European Working Group on Sarcopenia in Older People (2010) Sarcopenia: European consensus on definition and diagnosis: report of the European Working Group on Sarcopenia in older people. Age Ageing 39:412–423CrossRefPubMedPubMedCentralGoogle Scholar
  5. Cunningham C, Maclullich AM (2013) At the extreme end of the psychoneuroimmunological spectrum: delirium as a maladaptive sickness behavior response. Brain Behav Immun 28:1–13CrossRefPubMedGoogle Scholar
  6. Dittner AJ, Wessely SC, Brown RG (2004) The assessment of fatigue: a practical guide for clinicians and researchers. J Psychosom Res 56:157–170CrossRefPubMedGoogle Scholar
  7. Ernst F, Lübke N, Meinck M (2015) Kompendium Begutachtungswissen Geriatrie. Springer, HeidelbergCrossRefGoogle Scholar
  8. Extermann M, Boler I, Reich RR, Lyman GH, Brown RH, DeFelice J, Levine RM, Lubiner ET, Reyes P, Schreiber FJ 3rd, Balducci L (2012) Predicting the risk of chemotherapy toxicity in older patients: the Chemotherapy Risk Assessment Scale for High-age patients (CRASH) score. Cancer 118:3377–3386CrossRefPubMedGoogle Scholar
  9. Fiest KM, Roberts JI, Maxwell CJ, Hogan DB, Smith EE, Frolkis A, Cohen A, Kirk A, Pearson D, Pringsheim T, Venegas-Torres A, Jetté N (2016) The prevalence and incidence of dementia due to Alzheimer’s disease: a systematic review and meta-analysis. Can J Neurol Sci 43(Suppl 1):S51–S82CrossRefPubMedGoogle Scholar
  10. Franceschi C, Campisi J (2014) Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases. J Gerontol A Biol Sci Med Sci 69(Suppl 1):S4–S9CrossRefPubMedGoogle Scholar
  11. Fried LP, Tangen CM, Walston J, Newman AB, Hirsch C, Gottdiener J, Seeman T, Tracy R, Kop WJ, Burke G, McBurnie MA, Cardiovascular Health Study Collaborative Research Group (2001) Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci 56:M146–M156CrossRefPubMedGoogle Scholar
  12. Fulop T, McElhaney J, Pawelec G, Cohen AA, Morais JA, Dupuis G, Baehl S, Camous X, Witkowski JM, Larbi A (2015) Frailty, inflammation and immunosenescence. In: Theou O, Rockwood K (Hrsg) Frailty in aging. Karger, BaselGoogle Scholar
  13. Garfinkel D, Ilhan B, Bahat G (2015) Routine deprescribing of chronic medications to combat polypharmacy. Ther Adv Drug Saf 6:212–233CrossRefPubMedPubMedCentralGoogle Scholar
  14. Gillick M (1998) Choosing medical care in old age. Harvard University Press, BostonGoogle Scholar
  15. Horan MA (1998) Presentation of disease in old age. In: Tallis R, Fillit H, Brocklehurst JC (Hrsg) Geriatric medicine and gerontology. Churchill Livingstone, EdinburghGoogle Scholar
  16. Horneber M, Fischer I, Dimeo F, Rüffer JU, Weis J (2012) Tumor-assoziierte Fatigue. Dtsch Arztebl 109:161–171Google Scholar
  17. Inouye SK, Bogardus ST Jr, Baker DI, Leo-Summers L, Cooney LM Jr (2000) The hospital elder life program: a model of care to prevent cognitive and functional decline in older hospitalized patients. Hospital elder life program. J Am Geriatr Soc 48:1697–1706CrossRefPubMedGoogle Scholar
  18. Inouye SK, van Dyck CH, Alessi CA, Balkin S, Siegal AP, Horwitz RI (1990) Clarifying confusion: the confusion assessment method. A new method for detection of delirium. Ann Intern Med 113:941–948CrossRefPubMedGoogle Scholar
  19. Isaacs B (1969) Current achievements in geriatrics: morbidity in elderly hospital patients. Cassel, LondonGoogle Scholar
  20. Kaiser MJ, Bauer JM, Rämsch C, Uter W, Guigoz Y, Cederholm T, Thomas DR, Anthony PS, Charlton KE, Maggio M, Tsai AC, Vellas B, Sieber CC, Mini Nutritional Assessment International Group (2010) Frequency of malnutrition in older adults: a multinational perspective using the mini nutritional assessment. J Am Geriatr Soc 58:1734–1738CrossRefPubMedGoogle Scholar
  21. Kitwood T (2008) Demenz – Der personenzentrierte Ansatz, 5. Aufl. Hans Huber, BernGoogle Scholar
  22. Lim SH, Chan SW, He HG (2015) Patients’ experiences of performing self-care of stomas in the initial postoperative period. Cancer Nurs 38:185–193CrossRefPubMedGoogle Scholar
  23. Luo X, Chuang CC, Yang E, Zou KH, Araiza AL, Bhagnani T (2015) Prevalence, management and outcomes of medically complex vulnerable elderly patients with urinary incontinence in the United States. Int J Clin Pract 69:1517–1524CrossRefPubMedPubMedCentralGoogle Scholar
  24. Massie MJ (2004) Prevalence of depression in patients with cancer. J Natl Cancer Inst Monogr 32:57–71CrossRefGoogle Scholar
  25. McCarthy M (2015) US panel proposes new name and diagnostic criteria for chronic fatigue syndrome. BMJ 350:h775CrossRefPubMedGoogle Scholar
  26. Mitnitski AB, Graham JE, Mogilner AJ, Rockwood K (2002) Frailty, fitness and late-life mortality in relation to chronological and biological age. BMC Geriatr 2:1CrossRefPubMedPubMedCentralGoogle Scholar
  27. Muscaritoli M, Anker SD, Argilés J, Aversa Z, Bauer JM, Biolo G, Boirie Y, Bosaeus I, Cederholm T, Costelli P, Fearon KC, Laviano A, Maggio M, Rossi Fanelli F, Schneider SM, Schols A, Sieber CC (2010) Consensus definition of sarcopenia, cachexia and pre-cachexia: joint document elaborated by special interest groups (SIG) „cachexia-anorexia in chronic wasting diseases“ and „nutrition in geriatrics“. Clin Nutr 29:154–159CrossRefPubMedGoogle Scholar
  28. Presley CJ, Dotan E, Soto-Perez-de-Celis E, Jatoi A, Mohile SG, Won E, Alibhai S, Kilari D, Harrison R, Klepin HD, Wildes TM, Mustian K, Demark-Wahnefried W (2016) Gaps in nutritional research among older adults with cancer. J Geriatr Oncol 7:281–292CrossRefPubMedPubMedCentralGoogle Scholar
  29. Reed KL (2015) Key occupational therapy concepts in the person-occupation-environment-performance-model. In: Christiansen CH, Baum C, Bass JD (Hrsg) Occupational therapy – performance, participation, and well-being. SLACK Incorporated, ThorofareGoogle Scholar
  30. Resnick NM (1996) Geriatric incontinence. Urol Clin North Am 23:55–74CrossRefPubMedGoogle Scholar
  31. Rodríguez-Mañas L, Féart C, Mann G, Viña J, Chatterji S, Chodzko-Zajko W, Gonzalez-Colaço Harmand M, Bergman H, Carcaillon L, Nicholson C, Scuteri A, Sinclair A, Pelaez M, Van der Cammen T, Beland F, Bickenbach J, Delamarche P, Ferrucci L, Fried LP, Gutiérrez-Robledo LM, Rockwood K, Rodríguez Artalejo F, Serviddio G, Vega E, FOD-CC group (2013) Searching for an operational definition of frailty: a Delphi method based consensus statement: the frailty operative definition-consensus conference project. J Gerontol A Biol Sci Med Sci 68:62–67CrossRefPubMedGoogle Scholar
  32. Saß H, Wittchen HU, Zaudig M, Houben I (1998) Diagnostische Kriterien DSM-IV. Hogrefe, Göttingen (Dt. Bearbeitung)Google Scholar
  33. Siebens H (1990) Deconditioning. In: Kemp B, Brummel-Smith K, Ramsdell JW (Hrsg) Geriatric rehabilitation. Little, Brown, Boston, S 177–191Google Scholar
  34. Smets EM, Garssen B, Bonke B, De Haes JC (1995) The multidimensional fatigue inventory (MFI) psychometric qualities of an instrument to assess fatigue. J Psychosom Res 39:315–325CrossRefPubMedGoogle Scholar
  35. Tinetti ME, Speechley M (1989) Prevention of falls among the elderly. N Engl J Med 320:1055–1059CrossRefPubMedGoogle Scholar
  36. Valkenet K, van de Port IG, Dronkers JJ, de Vries WR, Lindeman E, Backx FJ (2011) The effects of preoperative exercise therapy on postoperative outcome: a systematic review. Clin Rehabil 25:99–111CrossRefPubMedGoogle Scholar
  37. Van Belle S, Paridaens R, Evers G, Kerger J, Bron D, Foubert J, Ponnet G, Vander Steichel D, Heremans C, Rosillon D (2005) Comparison of proposed diagnostic criteria with FACT-F and VAS for cancer-related fatigue: proposal for use as a screening tool. Support Care Cancer 13:246–254CrossRefPubMedGoogle Scholar
  38. Volkert D, Lenzen-Großimlinghaus R, Krys U et al (2004) Leitlinie Enterale Ernährung der DGEM und DGG: Leitlinie Enterale Ernährung (Trink- und Sondennahrung) in der Geriatrie und geriatrisch-neurologischen Rehabilitation. Aktuel Ernahrungsmed 29:198–225. Deutsche Zusammenfassung in Aktuel Ernaherungsmed 31:209–210. http://www.dgem.de
  39. Zhao KX, Huang CQ, Xiao Q, Gao Y, Liu QX, Wang ZR, Li YH, Xie YZ (2012) Age and risk for depression among the elderly: a meta-analysis of the published literature. CNS Spectr 17:142–154CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag GmbH Deutschland, ein Teil von Springer Nature 2018

Authors and Affiliations

  1. 1.IV. Medizinische KlinikUniversitätsmedizin MannheimMannheimDeutschland

Section editors and affiliations

  • Matthias Ebert
    • 1
  1. 1.II. Medizinischen KlinikUniversitätsmedizin MannheimMannheimDeutschland

Personalised recommendations