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Geriatrische Onkologie pp 535–543Cite as

Kutane Lymphome beim alten und geriatrischen Patienten

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Zusammenfassung

Kutane Lymphome sind überwiegend Erkrankungen des älteren und alten Menschen. Ihr Management erfordert eine stadiengerechte Therapie, d. h. frühe Stadien und indolente Formen können im allgemeinen mit lokalen Therapien behandelt werden, während spätere Stadien und aggressivere Varianten eine systemische Therapie erfordern. Explizite Therapieempfehlungen speziell für geriatrische Patienten existieren auf Grund der Seltenheit der Erkrankung und mangelnde durch vergleichende Studien belegte Evidenz nicht. Dabei besteht gerade für diese Patientengruppe ein erhöhtes Risiko, da ein hohes Alter einen negativen prognostischen Marker für kutane T-Zell-Lymphome darstellt und sich aggressivere B-Zell-Lymphome auch fast ausschließlich bei hochbetagten Patienten entwickeln. Trotz mangelnder altersspezifischer Therapieempfehlung muss die Therapieentscheidung bei geriatrischen Patienten häufig sehr individuell getroffen werden, da viele Kontraindikationen und Komorbiditäten speziell im höheren Patientenalter das Erstlinientherapiespektrum einschränken und ein Ausweichen auf alternative Optionen notwendig machen.

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Author information

Authors and Affiliations

  1. Klinik für Dermatologie, Venerologie und Allergologie, Universitätsmedizin Mannheim, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Deutschland

    Jan P. Nicolay & Sergij Goerdt

Authors
  1. Jan P. Nicolay
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  2. Sergij Goerdt
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Correspondence to Jan P. Nicolay .

Editor information

Editors and Affiliations

  1. II. Medizinische Klinik, Universitätsmedizin Mannheim, Mannheim, Germany

    Matthias Ebert

  2. II. Medizinische Klinik, Universitätsmedizin Mannheim, Mannheim, Germany

    Nicolai Härtel

  3. Klinik für Innere Medizin II, Universitätsklinikum Jena, Jena, Germany

    Ulrich Wedding

Section Editor information

  1. Interdisziplinäres Tumorzentrum, Universitätsmedizin Mannheim, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Deutschland

    Nicolai Härtel

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Nicolay, J.P., Goerdt, S. (2018). Kutane Lymphome beim alten und geriatrischen Patienten. In: Ebert, M., Härtel, N., Wedding, U. (eds) Geriatrische Onkologie. Springer Reference Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-48727-3_43

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  • DOI: https://doi.org/10.1007/978-3-662-48727-3_43

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