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Geriatrische Onkologie pp 483–496Cite as

Lungenkarzinom beim alten und geriatrischen Patienten

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Zusammenfassung

Angesichts der demographischen Entwicklung der kommenden Jahrzehnte wird der Anteil der älteren Lungenkrebs-Patienten bei einem aktuellen Altersmedian von 68 Jahren weiter ansteigen. Dabei ist höheres Lebensalter grundsätzlich kein alleiniger Ausschlussgrund für eine Therapiemodalität, vielmehr müssen individuell Allgemeinzustand und Komorbiditätsstatus berücksichtigt werden. In den frühen Stadien besteht in Hinsicht auf den Therapieerfolg eine leichtgradige Überlegenheit für die Lobektomie gegenüber einer sublobären Resektion, im Falle einer funktionellen Inoperabilität steht die stereotaktische Radiotherapie als sinnvolle Alternative zur Verfügung. Patienten in lokoregionär fortgeschrittenen Stadien werden wenn möglich radio-/chemotherapiert. Bei Einschränkungen wird auf eine kurativ dosierte alleinige Radiotherapie zurückgegriffen. Im fernmetastasierten Stadium kommen Carboplatin-haltige Kombinationsschemata oder Monotherapien zur Anwendung. Hier sind im Besonderen stratifizierbare zielgerichtete Therapien bei der Detektion von prädiktiven Biomarkern zu berücksichtigen. Nicht zu vernachlässigen ist im fortgeschrittenen Stadium die frühzeitige palliativmedizinische Versorgung im Hinblick auf Symptomkontrolle und psychosozialer Begleitung.

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Author information

Authors and Affiliations

  1. Internistische Onkologie der Thoraxtumoren, Thoraxklinik am Universitätsklinikum Heidelberg, Röntgenstr. 1, 69126, Heidelberg, Deutschland

    Martin Steins, Jonas Kuon & Michael Thomas

Authors
  1. Martin Steins
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  2. Jonas Kuon
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  3. Michael Thomas
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Corresponding author

Correspondence to Martin Steins .

Editor information

Editors and Affiliations

  1. II. Medizinische Klinik, Universitätsmedizin Mannheim, Mannheim, Germany

    Matthias Ebert

  2. II. Medizinische Klinik, Universitätsmedizin Mannheim, Mannheim, Germany

    Nicolai Härtel

  3. Klinik für Innere Medizin II, Universitätsklinikum Jena, Jena, Germany

    Ulrich Wedding

Section Editor information

  1. Interdisziplinäres Tumorzentrum, Universitätsmedizin Mannheim, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Deutschland

    Nicolai Härtel

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Steins, M., Kuon, J., Thomas, M. (2018). Lungenkarzinom beim alten und geriatrischen Patienten. In: Ebert, M., Härtel, N., Wedding, U. (eds) Geriatrische Onkologie. Springer Reference Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-48727-3_38

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  • DOI: https://doi.org/10.1007/978-3-662-48727-3_38

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