Zusammenfassung
Das Zervixkarzinom ist eine der häufigsten Karzinomerkrankungen der Frau. In den Entwicklungsländern ist das Zervixkarzinom nach wie vor die zweithäufigste Krebserkrankung der Frau (Jemal et al. 2011). In den entwickelten Ländern wiederum ist das Zervixkarzinom die vierthäufigste Krebserkrankung und das zweithäufigste gynäkologische Malignom der Frau. Das Zervixkarzinoms ist durch eine zweigipflige Altersverteilung charakterisiert mit Altersgipfel zwischen dem 30.–39. und 60.–69. Lebensjahr. Typisch für diese Altersgruppe ist, dass periodische Krebs-Vorsorgeuntersuchungen immer weniger in Anspruch genommen werden, was gerade beim Zervixkarzinom die Früherkennung beeinträchtigt. Folgen dieser Einstellung sind die späte Diagnose im fortgeschrittenen Krankheitsstadium. Bei einem ständigen Wachstum der Population der Frauen die 65 Jahre und älter sind, wird erwartet, dass Zervixkarzinome in dieser Altersgruppe zunehmen werden. Aktuell sind mehr als 40 % der an Zervixkarzinom gestorbenen Frauen älter als 65 Jahre.
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Literatur
Aa MA van der, Siesling S, v d Poll-Franse LV, Schutter EM, Lybeert ML, Coebergh JW (2009) Age-specific differences in the treatment of cervical cancer in the east and the south of The Netherlands 1989–2004. Eur J Obstet Gynecol Reprod Biol 147:78–82
Andrae B, Andersson TM, Lambert PC, Kemetli L, Silfverdal L, Strander B, Ryd W, Dillner J, Tornberg S, Sparen P (2012) Screening and cervical cancer cure: population based cohort study. BMJ 344, e900
Balducci L (2000) Geriatric oncology: challenges for the new century. Eur J Cancer 36:1741–1754
Castanon A, Landy R, Cuzick J, Sasieni P (2014) Cervical screening at age 50–64 years and the risk of cervical cancer at age 65 years and older: population-based case control study. PLoS Med 11, e1001585
Cesari M, Prince M, Thiyagarajan JA, De Carvalho IA, Bernabei R, Chan P, Gutierrez-Robledo LM, Michel JP, Morley JE, Ong P et al (2016) Frailty: an emerging public health priority. J Am Med Dir Assoc 17:188–192
Choi YS, Kim YH, Kang S, Jeon YT, Kim JW, Park NH, Song YS, Kang SB, Lee HP (2005) Feasibility of radical surgery in the management of elderly patients with uterine cervical cancer in Korea. Gynecol Obstet Invest 59:165–170
Elit L (2014a) Cervical cancer in the older woman. Maturitas 78:160–167
Elit L (2014b) Role of cervical screening in older women. Maturitas 79:413–420
Fox KV, Shah CA, Swisher EM, Garcia RL, Mandel LS, Gray HJ, Swensen RE, Goff BA (2008) An evaluation of cervical cancer in women age sixty and over. Gynecol Oncol 109:53–58
Goodheart M, Jacobson G, Smith BJ, Zhou L (2008) Chemoradiation for invasive cervical cancer in elderly patients: outcomes and morbidity. Int J Gynecol Cancer 18:95–103
Ioka A, Tsukuma H, Ajiki W, Oshima A (2005) Influence of age on cervical cancer survival in Japan. Jpn J Clin Oncol 35:464–469
Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D (2011) Global cancer statistics. CA Cancer J Clin 61:69–90
Kamineni A, Weinmann S, Shy KK, Glass AG, Weiss NS (2013) Efficacy of screening in preventing cervical cancer among older women. Cancer Causes Control 24:1653–1660
Lindegaard JC, Thranov IR, Engelholm SA (2000) Radiotherapy in the management of cervical cancer in elderly patients. Radiother Oncol 56:9–15
Lonnberg S, Nieminen P, Luostarinen T, Anttila A (2013) Mortality audit of the Finnish cervical cancer screening program. Int J Cancer 132:2134–2140
Mitchell PA, Waggoner S, Rotmensch J, Mundt AJ (1998) Cervical cancer in the elderly treated with radiation therapy. Gynecol Oncol 71:291–298
Mousavi A, Karimi Zarchi M, Gilani MM, Behtash N, Ghaemmaghami F, Shams M, Irvanipoor M (2008) Radical hysterectomy in the elderly. World J Surg Oncol 6:38
Park JY, Kim DY, Kim JH, Kim YM, Kim YT, Nam JH (2012) Laparoscopic versus open radical hysterectomy for elderly patients with early-stage cervical cancer. Am J Obstet Gynecol 207(195):e191–e198
Park JY, Kim DY, Kim JH, Kim YM, Kim YT, Nam JH (2013) Laparoscopic versus open radical hysterectomy in patients with stage IB2 and IIA2 cervical cancer. J Surg Oncol 108:63–69
Polanczyk CA, Marcantonio E, Goldman L, Rohde LE, Orav J, Mangione CM, Lee TH (2001) Impact of age on perioperative complications and length of stay in patients undergoing noncardiac surgery. Ann Intern Med 134:637–643
Rijke JM de, van der Putten HW, Lutgens LC, Voogd AC, Kruitwagen RF, van Dijck JA, Schouten LJ (2002) Age-specific differences in treatment and survival of patients with cervical cancer in the southeast of The Netherlands, 1986–1996. Eur J Cancer 38:2041–2047
Rose PG, Bundy BN, Watkins EB, Thigpen JT, Deppe G, Maiman MA, Clarke-Pearson DL, Insalaco S (1999) Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer. N Engl J Med 340:1144–1153
Rustagi AS, Kamineni A, Weinmann S, Reed SD, Newcomb P, Weiss NS (2014) Cervical screening and cervical cancer death among older women: a population-based, case-control study. Am J Epidemiol 179:1107–1114
Sasieni P, Adams J, Cuzick J (2003) Benefit of cervical screening at different ages: evidence from the UK audit of screening histories. Br J Cancer 89:88–93
Sasieni P, Castanon A, Cuzick J (2009) Effectiveness of cervical screening with age: population based case-control study of prospectively recorded data. BMJ 339:b2968
Sharma C, Deutsch I, Horowitz DP, Hershman DL, Lewin SN, Lu YS, Neugut AI, Herzog TJ, Chao CK, Wright JD (2012) Patterns of care and treatment outcomes for elderly women with cervical cancer. Cancer 118:3618–3626
Vicus D, Sutradhar R, Lu Y, Elit L, Kupets R, Paszat L, Investigators of the Ontario Cancer Screening Research Network (2014) The association between cervical cancer screening and mortality from cervical cancer: a population based case-control study. Gynecol Oncol 133:167–171
Wright JD, Gibb RK, Geevarghese S, Powell MA, Herzog TJ, Mutch DG, Grigsby PW, Gao F, Trinkaus KM, Rader JS (2005) Cervical carcinoma in the elderly: an analysis of patterns of care and outcome. Cancer 103:85–91
Yang B, Morrell S, Zuo Y, Roder D, Tracey E, Jelfs P (2008) A case-control study of the protective benefit of cervical screening against invasive cervical cancer in NSW women. Cancer Causes Control 19:569–576
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Ignatov, A., Costa, S.D. (2018). Zervixkarzinom bei der alten und geriatrischen Patientin. In: Ebert, M., Härtel, N., Wedding, U. (eds) Geriatrische Onkologie. Springer Reference Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-48727-3_34
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