Skip to main content

Zervixkarzinom bei der alten und geriatrischen Patientin

  • Chapter
  • First Online:
Geriatrische Onkologie

Part of the book series: Springer Reference Medizin ((SRM))

  • 1613 Accesses

Zusammenfassung

Das Zervixkarzinom ist eine der häufigsten Karzinomerkrankungen der Frau. In den Entwicklungsländern ist das Zervixkarzinom nach wie vor die zweithäufigste Krebserkrankung der Frau (Jemal et al. 2011). In den entwickelten Ländern wiederum ist das Zervixkarzinom die vierthäufigste Krebserkrankung und das zweithäufigste gynäkologische Malignom der Frau. Das Zervixkarzinoms ist durch eine zweigipflige Altersverteilung charakterisiert mit Altersgipfel zwischen dem 30.–39. und 60.–69. Lebensjahr. Typisch für diese Altersgruppe ist, dass periodische Krebs-Vorsorgeuntersuchungen immer weniger in Anspruch genommen werden, was gerade beim Zervixkarzinom die Früherkennung beeinträchtigt. Folgen dieser Einstellung sind die späte Diagnose im fortgeschrittenen Krankheitsstadium. Bei einem ständigen Wachstum der Population der Frauen die 65 Jahre und älter sind, wird erwartet, dass Zervixkarzinome in dieser Altersgruppe zunehmen werden. Aktuell sind mehr als 40 % der an Zervixkarzinom gestorbenen Frauen älter als 65 Jahre.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 159.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Literatur

  • Aa MA van der, Siesling S, v d Poll-Franse LV, Schutter EM, Lybeert ML, Coebergh JW (2009) Age-specific differences in the treatment of cervical cancer in the east and the south of The Netherlands 1989–2004. Eur J Obstet Gynecol Reprod Biol 147:78–82

    Google Scholar 

  • Andrae B, Andersson TM, Lambert PC, Kemetli L, Silfverdal L, Strander B, Ryd W, Dillner J, Tornberg S, Sparen P (2012) Screening and cervical cancer cure: population based cohort study. BMJ 344, e900

    Article  PubMed  PubMed Central  Google Scholar 

  • Balducci L (2000) Geriatric oncology: challenges for the new century. Eur J Cancer 36:1741–1754

    Article  CAS  PubMed  Google Scholar 

  • Castanon A, Landy R, Cuzick J, Sasieni P (2014) Cervical screening at age 50–64 years and the risk of cervical cancer at age 65 years and older: population-based case control study. PLoS Med 11, e1001585

    Article  PubMed  PubMed Central  Google Scholar 

  • Cesari M, Prince M, Thiyagarajan JA, De Carvalho IA, Bernabei R, Chan P, Gutierrez-Robledo LM, Michel JP, Morley JE, Ong P et al (2016) Frailty: an emerging public health priority. J Am Med Dir Assoc 17:188–192

    Article  PubMed  Google Scholar 

  • Choi YS, Kim YH, Kang S, Jeon YT, Kim JW, Park NH, Song YS, Kang SB, Lee HP (2005) Feasibility of radical surgery in the management of elderly patients with uterine cervical cancer in Korea. Gynecol Obstet Invest 59:165–170

    Article  PubMed  Google Scholar 

  • Elit L (2014a) Cervical cancer in the older woman. Maturitas 78:160–167

    Article  PubMed  Google Scholar 

  • Elit L (2014b) Role of cervical screening in older women. Maturitas 79:413–420

    Article  PubMed  Google Scholar 

  • Fox KV, Shah CA, Swisher EM, Garcia RL, Mandel LS, Gray HJ, Swensen RE, Goff BA (2008) An evaluation of cervical cancer in women age sixty and over. Gynecol Oncol 109:53–58

    Article  PubMed  Google Scholar 

  • Goodheart M, Jacobson G, Smith BJ, Zhou L (2008) Chemoradiation for invasive cervical cancer in elderly patients: outcomes and morbidity. Int J Gynecol Cancer 18:95–103

    Article  CAS  PubMed  Google Scholar 

  • Ioka A, Tsukuma H, Ajiki W, Oshima A (2005) Influence of age on cervical cancer survival in Japan. Jpn J Clin Oncol 35:464–469

    Article  PubMed  Google Scholar 

  • Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D (2011) Global cancer statistics. CA Cancer J Clin 61:69–90

    Article  PubMed  Google Scholar 

  • Kamineni A, Weinmann S, Shy KK, Glass AG, Weiss NS (2013) Efficacy of screening in preventing cervical cancer among older women. Cancer Causes Control 24:1653–1660

    Article  PubMed  Google Scholar 

  • Lindegaard JC, Thranov IR, Engelholm SA (2000) Radiotherapy in the management of cervical cancer in elderly patients. Radiother Oncol 56:9–15

    Article  CAS  PubMed  Google Scholar 

  • Lonnberg S, Nieminen P, Luostarinen T, Anttila A (2013) Mortality audit of the Finnish cervical cancer screening program. Int J Cancer 132:2134–2140

    Article  PubMed  Google Scholar 

  • Mitchell PA, Waggoner S, Rotmensch J, Mundt AJ (1998) Cervical cancer in the elderly treated with radiation therapy. Gynecol Oncol 71:291–298

    Article  CAS  PubMed  Google Scholar 

  • Mousavi A, Karimi Zarchi M, Gilani MM, Behtash N, Ghaemmaghami F, Shams M, Irvanipoor M (2008) Radical hysterectomy in the elderly. World J Surg Oncol 6:38

    Article  PubMed  PubMed Central  Google Scholar 

  • Park JY, Kim DY, Kim JH, Kim YM, Kim YT, Nam JH (2012) Laparoscopic versus open radical hysterectomy for elderly patients with early-stage cervical cancer. Am J Obstet Gynecol 207(195):e191–e198

    Google Scholar 

  • Park JY, Kim DY, Kim JH, Kim YM, Kim YT, Nam JH (2013) Laparoscopic versus open radical hysterectomy in patients with stage IB2 and IIA2 cervical cancer. J Surg Oncol 108:63–69

    Article  PubMed  Google Scholar 

  • Polanczyk CA, Marcantonio E, Goldman L, Rohde LE, Orav J, Mangione CM, Lee TH (2001) Impact of age on perioperative complications and length of stay in patients undergoing noncardiac surgery. Ann Intern Med 134:637–643

    Article  CAS  PubMed  Google Scholar 

  • Rijke JM de, van der Putten HW, Lutgens LC, Voogd AC, Kruitwagen RF, van Dijck JA, Schouten LJ (2002) Age-specific differences in treatment and survival of patients with cervical cancer in the southeast of The Netherlands, 1986–1996. Eur J Cancer 38:2041–2047

    Google Scholar 

  • Rose PG, Bundy BN, Watkins EB, Thigpen JT, Deppe G, Maiman MA, Clarke-Pearson DL, Insalaco S (1999) Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer. N Engl J Med 340:1144–1153

    Article  CAS  PubMed  Google Scholar 

  • Rustagi AS, Kamineni A, Weinmann S, Reed SD, Newcomb P, Weiss NS (2014) Cervical screening and cervical cancer death among older women: a population-based, case-control study. Am J Epidemiol 179:1107–1114

    Article  PubMed  PubMed Central  Google Scholar 

  • Sasieni P, Adams J, Cuzick J (2003) Benefit of cervical screening at different ages: evidence from the UK audit of screening histories. Br J Cancer 89:88–93

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Sasieni P, Castanon A, Cuzick J (2009) Effectiveness of cervical screening with age: population based case-control study of prospectively recorded data. BMJ 339:b2968

    Article  PubMed  PubMed Central  Google Scholar 

  • Sharma C, Deutsch I, Horowitz DP, Hershman DL, Lewin SN, Lu YS, Neugut AI, Herzog TJ, Chao CK, Wright JD (2012) Patterns of care and treatment outcomes for elderly women with cervical cancer. Cancer 118:3618–3626

    Article  PubMed  Google Scholar 

  • Vicus D, Sutradhar R, Lu Y, Elit L, Kupets R, Paszat L, Investigators of the Ontario Cancer Screening Research Network (2014) The association between cervical cancer screening and mortality from cervical cancer: a population based case-control study. Gynecol Oncol 133:167–171

    Article  PubMed  Google Scholar 

  • Wright JD, Gibb RK, Geevarghese S, Powell MA, Herzog TJ, Mutch DG, Grigsby PW, Gao F, Trinkaus KM, Rader JS (2005) Cervical carcinoma in the elderly: an analysis of patterns of care and outcome. Cancer 103:85–91

    Article  PubMed  Google Scholar 

  • Yang B, Morrell S, Zuo Y, Roder D, Tracey E, Jelfs P (2008) A case-control study of the protective benefit of cervical screening against invasive cervical cancer in NSW women. Cancer Causes Control 19:569–576

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Atanas Ignatov .

Editor information

Editors and Affiliations

Section Editor information

Rights and permissions

Reprints and permissions

Copyright information

© 2018 Springer-Verlag GmbH Deutschland, ein Teil von Springer Nature

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Ignatov, A., Costa, S.D. (2018). Zervixkarzinom bei der alten und geriatrischen Patientin. In: Ebert, M., Härtel, N., Wedding, U. (eds) Geriatrische Onkologie. Springer Reference Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-48727-3_34

Download citation

  • DOI: https://doi.org/10.1007/978-3-662-48727-3_34

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-48726-6

  • Online ISBN: 978-3-662-48727-3

  • eBook Packages: Medicine (German Language)

Publish with us

Policies and ethics