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Pädiatrische Neurochirurgie pp 333–343Cite as

Syndromale Kraniosynostosen

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Zusammenfassung

Syndromale Kraniosynostosen sind insgesamt selten und in vielen Fällen auf genetische Spontanmutationen bestimmter Kandidatengene für die Knochenentwicklung zurückzuführen. In familiären Fällen überwiegen autosomal dominante Erbgänge. Die Diagnosestellung und langfristige Betreuung der betroffenen Patienten ist immer eine interdisziplinäre Aufgabe und oftmals nur nach sorgfältiger humangenetischer Untersuchung möglich. Die Therapieprinzipien richten sich stets nach den häufig variablen phänotypischen Ausprägungen und haben insbesondere eine Dekompression des wachsenden Gehirns und der Orbitastrukturen sowie funktionelle Verbesserungen im Gesichtsbereich zum Ziel.

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Authors and Affiliations

  1. Chefärztin der Abteilung Kinderneurochirurgie Asklepios Kinderklinik, Arnold-Janssen-Straße 29, Sankt Augustin, 53757, Deutschland

    A. M. Messing-Jünger

  2. Klinik und Poliklinik für Mund-, Kiefer- und Plastische Gesichtschirurgie, Universitätsklinikum Bonn, Sigmund-Freud-Str. 25, Bonn, 53127, Deutschland

    M. Martini

Authors
  1. A. M. Messing-Jünger
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  2. M. Martini
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Correspondence to A. M. Messing-Jünger .

Editor information

Editors and Affiliations

  1. Sektionsleiterin Pädiatrische Neurochirurgie, Neurochirurgische Klinik Universitätsklinikum, Heidelberg, Germany

    Heidi Bächli

  2. Universitätskinderklinik beider Basel (UKBB), Binningen, Switzerland

    Jürg Lütschg

  3. Chefärztin der Abteilung Kinderneurochirurgie Asklepios Kinderklinik, Sankt Augustin, Germany

    Martina Messing-Jünger

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Messing-Jünger, A.M., Martini, M. (2018). Syndromale Kraniosynostosen . In: Bächli, H., Lütschg, J., Messing-Jünger, M. (eds) Pädiatrische Neurochirurgie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-48700-6_31

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  • DOI: https://doi.org/10.1007/978-3-662-48700-6_31

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-48699-3

  • Online ISBN: 978-3-662-48700-6

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