Organic Dye-Loaded Nanoparticles for Imaging-Guided Cancer Therapy

  • Zonghai Sheng
  • Lintao CaiEmail author
Part of the Springer Series in Biomaterials Science and Engineering book series (SSBSE, volume 6)


Recently, organic dye-based imaging-guided cancer therapy has attracted much attention in the field of cancer nanomedicine. As a small molecular compound, organic dye has an exact molecular weight and chemical structure. It can be not only used as fluorescence and photoacoustic imaging probes but also applied as therapeutic agents for photodynamic and photothermal therapy. Functionalized with the different delivery nanomaterials, organic dyes exhibit a long halftime and high tumor targeting and promoted stability. In this chapter, we review the development of organic dyes for cancer imaging and therapy applications in decades and illustrate the use of functional nanomaterials as organic dye delivery systems for enhancing their stability and tumor targeting, which show the bright prospects and challenges toward organic dye-based imaging-guided cancer therapy.


Organic dye Imaging-guided therapy Theranostics Fluorescence imaging Photoacoustic imaging Photodynamic therapy Photothermal therapy Photoimmunotherapy 


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© Springer-Verlag Berlin Heidelberg 2016

Authors and Affiliations

  1. 1.Guangdong Key Laboratory of Nanomedicine, Institute of Biomedicine and BiotechnologyShenzhen Institutes of Advanced Technology, Chinese Academy of SciencesShenzhenPeople’s Republic of China

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