Metalworking Fluids

  • Johannes GeierEmail author


Metalworking fluids (MWFs) are a frequent cause of occupational irritant and/or allergic contact dermatitis in metalworkers.

The most important allergens in water-based MWF are monoethanolamine (MEA) and oxidation products of resin acids. Resin acids are contained in distilled tall oil, which is a widely used basic MWF component. Sensitization to their oxidation products, which are formed in the MWF during the working process, is detected by patch testing with colophonium. Other frequent sensitizers in MWF are formaldehyde, formaldehyde releasers, and other biocides such as isothiazolinones. Various other allergens have been described in single cases. Patch testing with the MWF from the patients’ workplace is crucial in the diagnostic work-up suspected MWF dermatitis.


Abietic acid Biocides Colophonium Contact allergy Formaldehyde Formaldehyde releasers Irritant contact dermatitis Metalworking fluids Monoethanolamine Neat oils Occupational dermatitis 


  1. 1.
    Allenby CF, Basketter DA. Minimum eliciting patch test concentrations of cobalt. Contact Dermatitis. 1989;20:185–90.CrossRefPubMedGoogle Scholar
  2. 2.
    de Groot AC, Flyvholm M-A. Formaldehyde and formaldehyde-releasers. In: Rustemeyer T, Elsner P, John SM, Maibach HI, editors. Kanerva’s occupational dermatology. 2nd ed. Berlin: Springer; 2012. p. 397–413.CrossRefGoogle Scholar
  3. 3.
    Foulds IS. Cutting fluids. In: Rustemeyer T, Elsner P, John SM, Maibach HI, editors. Kanerva’s occupational dermatology. 2nd ed. Berlin: Springer; 2012. p. 715–25.CrossRefGoogle Scholar
  4. 4.
    Geier J, Lessmann H. Metalworking fluids. In: Johansen JD, Frosch PJ, Lepoittevin JP, editors. Contact dermatitis. 5th ed. Berlin: Springer; 2011. p. 681–94.CrossRefGoogle Scholar
  5. 5.
    Geier J, Lessmann H, Dickel H, Frosch PJ, Koch P, Becker D, et al. Patch test results with the metalworking fluid series of the German contact dermatitis research group (DKG). Contact Dermatitis. 2004;51:118–30.CrossRefPubMedGoogle Scholar
  6. 6.
    Geier J, Lessmann H, Schnuch A, Uter W. Contact sensitizations in metalworkers with occupational dermatitis exposed to water-based metalworking fluids. Results of the research project “FaSt”. Int Arch Occup Environ Health. 2004;77:543–51.CrossRefPubMedGoogle Scholar
  7. 7.
    Geier J, Lessmann H, Schumacher T, Eckert C, Becker D, Boveleth W, et al. Vorschlag für die Epikutantestung bei Verdacht auf Kontaktallergie durch Kühlschmierstoffe. 1. Kommerziell erhältliche Testsubstanzen. Dermatol Beruf Umwelt. 2000;48:232–6.Google Scholar
  8. 8.
    Geier J, Lessmann H, Skudlik C, Weisshaar E, Schnuch A. Kontaktallergie gegen Bestandteile von Kühlschmierstoffen. IVDK-Daten der Jahre 2005–2009. Dermatol Beruf Umwelt. 2013;61:137–49.CrossRefGoogle Scholar
  9. 9.
    Geier J, Uter W, Lessmann H, Frosch PJ. Patch testing with metalworking fluids from the patient’s workplace. Contact Dermatitis. 2004;51:172–9.CrossRefPubMedGoogle Scholar
  10. 10.
    Goncalo M, Goossens A, on behalf of the ESCD. Whilst Rome burns: the epidemic of contact allergy to methylisothiazolinone. Contact Dermatitis. 2013;68:257–8.CrossRefPubMedGoogle Scholar
  11. 11.
    Karlberg A-T. Air oxidation increases the allergenic potential of tall-oil rosin. Colophonium contact allergens also identified in tall-oil rosin. Am J Contact Dermatol. 1991;2:43–9.CrossRefGoogle Scholar
  12. 12.
    Krbek F, Schäfer T. Untersuchungen an Tropfen und Rückständen von wassermischbaren Kühlschmierstoffen. Arbeitsmed Sozialmed Präventivmed. 1991;26:411–6.Google Scholar
  13. 13.
    Kütting B, Weistenhöfer W, Baumeister T, Uter W, Drexler H. Current acceptance and implementation of preventive strategies for occupational hand eczema in 1355 metalworkers in Germany. Br J Dermatol. 2009;161:390–6.CrossRefPubMedGoogle Scholar
  14. 14.
    Lessmann H, Uter W, Schnuch A, Geier J. Skin sensitizing properties of the ethanolamines mono-, di-, and triethanolamine. Data analysis of a multicentre surveillance network (IVDK) and review of the literature. Contact Dermatitis. 2009;60:243–55.CrossRefPubMedGoogle Scholar
  15. 15.
    Tiedemann K-H, Zoellner G, Adam M, Becker D, Boveleth W, Eck E, et al. Empfehlungen für die Epikutantestung bei Verdacht auf Kontaktallergie durch Kühlschmierstoffe. 2. Hinweise zur Arbeitsstofftestung. Dermatol Beruf Umwelt. 2002;50:180–9.Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2016

Authors and Affiliations

  1. 1.IVDKUniversity of GöttingenGöttingenGermany

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