Endoscopic Intervention

  • Sung-Hoon Moon
  • Myung-Hwan KimEmail author


Any attempt to treat pancreatic cancer aggressively usually creates a frustrating and difficult situation for clinicians, as their patients with advanced pancreatic cancer can suffer from pain, biliary obstruction, and intestinal obstruction. The expected survival is mostly short in locally advanced/metastatic pancreatic cancer patients. The role of endoscopic intervention in pancreatic cancer patients is largely palliation of the later manifestation of the disease, whereas endoscopy also has a role in preoperative biliary drainage of potentially resectable cancer of the pancreatic head in selected patients. Endoscopic biliary stenting using various stent is now accepted as a primary option for the palliation of biliary obstruction by pancreatic cancer. Endoscopic insertion of duodenal stents also has demonstrated adequate safety and high technical success. Endoscopic ultrasound-guided celiac plexus/ganglia neurolysis significantly improves pain relief and the quality of life in patients with advanced pancreatic cancer. Pancreatic duct stenting can also be performed for pain of pancreatic duct obstructive quality. Initial endoscopic approach to palliation should be attempted in the preoperatively identified unresectable disease. Surgery remains an effective method of palliation when endoscopic or percutaneous palliation is not feasible or failed.


Pancreatic Cancer Biliary Drainage Biliary Obstruction Advanced Pancreatic Cancer Percutaneous Transhepatic Biliary Drainage 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2017

Authors and Affiliations

  1. 1.Department of Internal MedicineHallym University College of Medicine, Hallym University Sacred Heart HospitalAnyangRepublic of Korea
  2. 2.Department of Internal MedicineUniversity of Ulsan College of Medicine, Asan Medical CenterSeoulRepublic of Korea

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