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Electroanalysis in Biomedical and Pharmaceutical Sciences pp 7–44Cite as

Polarography in Studies of Pharmaceuticals

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Part of the book series: Monographs in Electrochemistry ((MOEC))

Abstract

Polarography is an electroanalytical technique based on recording of current–voltage (i−E) curves using electrolysis, with a dropping mercury electrode (DME) as an indicator electrode. This technique has been invented in 1922 by Heyrovsky [1]. For his invention, he was awarded in 1959 the Nobel Prize. According to the Analytical Chemistry, polarography has been over the period from 1950 to 1970 one of the five most frequently used analytical techniques. The scope of its worldwide applications suffered a decline more recently, because of the wide range of separation techniques in organic analysis. Similarly, the use of atomic absorption (AA) and related techniques became predominant in the determination of metal ions. As reflected by the number of references in the Tables, polarography is currently used in those laboratories, where limited budgets do not allow acquiring of more expensive instrumentation, as needed in AA and modern separation techniques.

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Authors and Affiliations

  1. Faculty of Pharmacy Department of Analytical Chemistry, Ankara University, Tandogan, Ankara, Ankara, Turkey

    Sibel A. Ozkan

  2. Faculty of Pharmacy, Université Libre de Bruxelles, Brussels, Belgium

    Jean-Michel Kauffmann

  3. Department of Chemistry and Biomolecular Science, Clarkson University, Potsdam, New York, USA

    Petr Zuman

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  1. Sibel A. Ozkan
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  2. Jean-Michel Kauffmann
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  3. Petr Zuman
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Ozkan, S.A., Kauffmann, JM., Zuman, P. (2015). Polarography in Studies of Pharmaceuticals. In: Electroanalysis in Biomedical and Pharmaceutical Sciences. Monographs in Electrochemistry. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-47138-8_2

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