Zusammenfassung
Heutzutage ist eine exzellente morphologische Knorpelbildgebung möglich, die auch feinste Knorpelpathologien darstellen kann. Neben den Standard-2-D-Sequenzen ist eine Vielzahl von 3-D-Sequenzen zur hochaufgelösten Knorpeldarstellung verfügbar. Im ersten Teil dieses Artikels werden daher die aktuellen Möglichkeiten der morphologischen Diagnostik beleuchtet. Der zweite Teil behandelt die funktionelle Knorpelbildgebung. Mit ihr ist es möglich, Veränderungen der Knorpelkomposition und somit Frühformen von Knorpelschädigungen zu erfassen bzw. diese biochemischen Veränderungen nach therapeutischer Intervention zu evaluieren. Hierbei werden bereits validierte Techniken wie dGEMRIC oder „T2-Mapping“ besprochen, aber auch neueste Techniken wie die gagCEST-Technik beleuchtet.
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Rehnitz, C., Weber, MA. (2015). Morphologische und funktionelle Knorpeldiagnostik. In: Delorme, S., Reimer, P., Reith, W., Schäfer-Prokop, C., Schüller-Weidekamm, C., Uhl, M. (eds) Weiterbildung Radiologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-46785-5_12
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