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Penile Augmentation pp 205–211Cite as

Modified Tissue Engineering Techniques Using Stem Cells

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Abstract

Penile reconstruction may be required under some conditions such as penile malignancy, trauma, congenital genitourinary anomalies, and Peyronie’s disease (PD). The traditional penile reconstructive procedures cannot fulfill to restore a functionally and cosmetically satisfactory penis and have complications such as immunological rejection and psychological problems. One of the major structures of the penis is the corpus cavernosum. The penile corpus cavernosum is composed of sinusoids that are surrounded by the layers of endothelial cells (ECs) and smooth muscle cells (SMCs). Erectile function of penile corpus cavernosum is dependent on these two kinds of cells [1]. The therapeutic uses of stem cells (SCs) and tissue engineering (TE) techniques are emerging in urology. SCs are undifferentiated cells capable of proliferation, self-renewal, and differentiation into different cell types including ECs, SMCs, Schwann cells, and neurons [2]. SC therapy for penile tissue regeneration (TE) might replenish the depleted ECs and SMCs. Therefore, TE for penile tissue regeneration using SCs may have a huge potential and could be a novel treatment option for ideal penile reconstruction.

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Author information

Authors and Affiliations

  1. Department of Urology, Kangbuk Samsung Hospital, Sungkyunkwan University, School of Medicine, Seoul, South Korea

    Heung Jae Park MD, PhD

  2. Department of Urology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, South Korea

    Kyung Hyun Moon

Authors
  1. Heung Jae Park MD, PhD
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  2. Kyung Hyun Moon
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Corresponding authors

Correspondence to Heung Jae Park MD, PhD or Kyung Hyun Moon .

Editor information

Editors and Affiliations

  1. Pusan National University Hospital, Busan, Korea (Republic of)

    Nam Cheol Park

  2. Seoul St. Mary's Hospital, Seoul, Korea (Republic of)

    Sae Woong Kim

  3. Korea University Guro Hospital, Seoul, Korea (Republic of)

    Du Geon Moon

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© 2016 Springer-Verlag Berlin Heidelberg

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Park, H.J., Moon, K.H. (2016). Modified Tissue Engineering Techniques Using Stem Cells. In: Park, N., Kim, S., Moon, D. (eds) Penile Augmentation. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-46753-4_25

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  • DOI: https://doi.org/10.1007/978-3-662-46753-4_25

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-46752-7

  • Online ISBN: 978-3-662-46753-4

  • eBook Packages: MedicineMedicine (R0)

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