Skip to main content
SpringerLink
Log in
Book cover

Weiterbildung Intensivmedizin und Notfallmedizin pp 21–32Cite as

Psychopharmakotherapie im Notarztdienst

  • Chapter

  • 2377 Accesses

Zusammenfassung

Der vorliegende CME-Artikel setzt sich mit der Pharmakotherapie psychischer Störungen im Notarztdienst auseinander. Im Gegensatz zum Vorgehen bei somatischen Notfällen ist die Pharmakotherapie psychiatrischer Notfälle vielen Notfallmedizinern häufig nicht ausreichend bekannt, obwohl hierfür ebenfalls Leitlinien und Empfehlungen existieren. Im vorliegenden Beitrag werden für die 5 notfallmedizinisch relevanten Syndrome Suizidalität, Delir, psychomotorische Erregungszustände, Stupor und Dissoziation sowie psychopharmakainduzierte Syndrome die aktuellen Therapieempfehlungen, wie sie auch in der demnächst erscheinenden S2-Leitlinie Notfallpsychiatrie beschrieben werden, dargestellt.

This is a preview of subscription content, log in via an institution.

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   29.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  1. Wolf A, Müller MJ, Pajonk FG (2013) Psychopharmaka im Notarztdienst. Notfall Rettungsmed 16:397–407

    Article  Google Scholar 

  2. Müller MJ, Lange-Asschenfeldt C (2012) Pharmakotherapie psychiatrischer Notfallsituationen. In: Gründer G, Benkert O (Hrsg) Handbuch der Psychopharmakotherapie. Springer, Berlin Heidelberg New York Tokio, S1123–1135

    Chapter  Google Scholar 

  3. Flüchter P, Müller V, Pajonk FG (2012) Suizidalität: Procedere im Notfall. Med Klin Intensivmed Notfallmed 107(6):469–475

    Article  Google Scholar 

  4. Deutsche Gesellschaft für Psychiatrie, Psychotherapie und Nervenheilkunde (DGPPN) (2010) Therapeutische Maßnahmen bei aggressivem Verhalten in der Psychiatrie und Psychotherapie. AWMF-Leltllnienregis- ternummer 038/022. AWMF, Düsseldorf. http://www.awmf.org/uplo-ads/tx_szleitlinlen/038-022_S2_The-rapeutische_Massnahmen_bei_aggressivem_Verhalten_in_der_Psychiatrie_und_Psychotheraple_lang_08-2009_08-2014.pdf. Zugegriffen: 01.07.2013

  5. Benkert O, Hippius H (2010) Kompendium der psychiatrischen Pharmakotherapie. Springer, Berlin Heidelberg New York Tokio

    Google Scholar 

  6. De Fruyt J, Demyttenaere K (2004) Rapid tranquilization: new approaches in the emergency treatment of behavioral disturbances. Eur Psychiatry 19:243–249

    Article  PubMed  Google Scholar 

  7. Wilson MP, Pepper D, Currier GW et al (2012) The psychopharmacology of agitation: consensus statement of the American Association for Emergency Psychiatry Project Beta Psychopharmacology Workgroup. West J Emerg Med 13:26–34

    Article  PubMed Central  PubMed  Google Scholar 

  8. Breier A, Meehan K, Birkett M et al (2002) A double-blind, placebo-controlled dose-response comparison of intramuscular olanzapine and haloperidol in the treatment of acute agitation in schizophrenia. Arch Gen Psychiatry 59:441 -448

    Article  Google Scholar 

  9. Citrome L, Volavka J, Czobor P et al (2006) Efficacy of ziprasidone against hostility In schizophrenia: post hoc analysis of randomized, open-label study data. J Clin Psychiatry 67:638642

    Article  Google Scholar 

  10. Wright P, Blrkett M, David SR et al (2001) Double-blind, placebo-controlled comparison of intramuscular olanzapine and intramuscular haloperidol In the treatment of acute agitation in schizophrenia. Am J Psychiatry 158:1149–1151

    Article  CAS  PubMed  Google Scholar 

  11. Battaglia J, Moss S, Rush J et al (1997) Haloperidol, lorazépam, or both for psychotic agitation? A multicenter, prospective, double-blind, emergency department study. Am J Emerg Med 15:335–340

    Article  CAS  PubMed  Google Scholar 

  12. Bieniek SA, Ownby RL, Penalver A et al (1998) A double-blind study of lorazépam versus the combination of haloperidol and lorazépam in managing agitation. Pharmacotherapy 18:57–62

    CAS  PubMed  Google Scholar 

  13. Dorevitch A, Katz N, Zemishlany Z et al (1999) Intramuscular flunltraze- pam versus intramuscular haloperidol in the emergency treatment of aggressive psychotic behavior. Am J Psychiatry 156:142–144

    Article  CAS  PubMed  Google Scholar 

  14. Foster S, Kessel J, Berman ME et al (1997) Efficacy of lorazépam and haloperidol for rapid tranquilization in a psychiatric emergency room setting. Int Clin Psychopharmacol 12:175–179

    Article  CAS  PubMed  Google Scholar 

  15. Garza-Trevino ES, Hollister LE, Overall JE et al (1989) Efficacy of combinations of intramuscular antipsychotics and sedative-hypnotics for control of psychotic agitation. Am J Psychiatry 146:1598–1601

    Article  CAS  PubMed  Google Scholar 

  16. Wyant M, Diamond Bl, O'neal E et al (1990) The use of midazolam in acutely agitated psychiatric patients. Psychopharmacol Bull 26:126–129

    CAS  PubMed  Google Scholar 

  17. Huf G, Alexander J, Allen MH (2005) Haloperidol plus promethazine for psychosis Induced aggression. Cochrane Database Syst Rev 1:CD005146

    PubMed  Google Scholar 

  18. Huf G, Alexander J, Allen MH et al (2009) Haloperidol plus promethazine for psychosis-induced aggression. Cochrane Database Syst Rev 3:CD005146

    PubMed  Google Scholar 

  19. SatterthwaiteTD.Wolf DH, Rosenheck RA et al (2008) A meta-analysis of the risk of acute extrapyramidal symptoms with intramuscularantip- sychotics for the treatment of agitation. J Clin Psychiatry 69:1869–1879

    Article  Google Scholar 

  20. DubinWR, Weiss KJ (1986) Rapid tranquilization: a comparison of thiothixene with loxaplne. J Clin Psychiatry 47:294–297

    Google Scholar 

  21. Allen MH, Feifel D, Lesem MD et al (2011) Efficacy and safety of loxaplne for inhalation In the treatment of agitation in patients with schizophrenia: a randomized, doubleblind, placebo-controlled trial. J Clin Psychiatry 72:1313–1321

    Article  CAS  PubMed  Google Scholar 

  22. KwentusJ, RiesenbergRA, Marandi M et al (2012) Rapid acute treatment of agitation in patients with bipolar I disorder: a multicenter, randomized, placebo-controlled clinical trial with inhaled loxapine. Bipolar Disord 14:31–40

    Article  Google Scholar 

  23. Lesem MD, Tran-Johnson TK, Riesenberg RA et al (2011) Rapid acute treatment of agitation in individuals with schizophrenia: multicentre, randomised, placebo-controlled study of Inhaled loxapine. Br J Psychiatry 198:51–58

    Article  PubMed  Google Scholar 

  24. Citrome L (2011) Aerosolised antipsychotic assuages agitation: inhaled loxapine for agitation associated with schizophrenia or bipolar disorder. Int J Clin Pract 65:330–340

    Article  CAS  PubMed  Google Scholar 

  25. Citrome L (2007) Comparison of intramuscular ziprasidone, olanzapine, or aripiprazole for agitation: a quantitative review of efficacy and safety. J Clin Psychiatry 68:1876–1885

    Article  CAS  PubMed  Google Scholar 

  26. CurrierGW, CitromeLL, ZimbroffDL etal (2007) Intramuscular aripiprazole in the control of agitation. J Psy- chiatr Pract 13:159–169

    Article  Google Scholar 

  27. Belgamwar RB, Fenton M (2005) Olanzapine IM or velotab for acutely disturbed/agitated people with suspected serious mental Illnesses. Cochrane Database Syst Rev 2D003729

    Google Scholar 

  28. Gillies D. Beck A, Mccloud A et al (2005) Benzodiazepines alone or. in combination with antipsycholic drugs for acute psychosis. Cochrane Database Syst Rev 4:CD00307–9

    Google Scholar 

  29. Zisselman MH, Jaffe RL (2010) ECT in the treatment of a patient with catatonia, consent and complications. Am J Psychiatry 167:127–132

    PubMed  Google Scholar 

  30. Schmider J, Standhart, Deuschle M et al (1999) A double-blind comparison of lorazepam and oxazepam in psychomotor retardation and mutism. Biol Psychlatry 46:437–441

    Google Scholar 

  31. Wetzel H, Heuser I, Benkert O (1988) Benzodiazepines for catatonic symptoms, stupor, and mutism. Pharmacopsychiatry 21:394–395

    Article  PubMed  Google Scholar 

  32. AborayaA, Chumber p. Altaha B (2009) The treatment resistant catatonic patient. Curr Psychiatr 8:66–69

    Google Scholar 

  33. Babington PW, Spiegel DR (2007) Treatment of catatonia with olanzapine and amantadine. Psychosomaties48:S34–536

    Google Scholar 

  34. Kirino E (2010) Prokmged catatonic stupor successfully treated with ariplprazole in an adolescent male with schizophrenia a case report. Clin Schizophr Relat Psychoses 4:185–188

    Google Scholar 

  35. Peralta V, Campos MS. De Jalon EG et al (2010) DSM-IV catatonia signs and criteria in first-episode, drug-naive, psychotic patients: psychometric validity and response to antipsychoticmedication. Schizophr Res 118:168–175

    PubMed  Google Scholar 

  36. Alexander J, Tharyan P, Adams C et al (2004) Rapid tranquillisation of violent or agitated patients in a psychiatric emergency setting. Pragmatic randomised trial of Intramuscular lo- razepam v. haloperidol plus promethazine. Br J Psychiatry 185:63–69

    Article  PubMed  Google Scholar 

  37. Haverkamp W, Deuschle M (2006) Antipsychotikainduzierte QT-Ver- langerung. Nervenarzt 77:276,278280,282–274

    Google Scholar 

  38. JANSSEN-CILAG GmbH, Neuss (Stand Dezember 2011) Fachinformation Haldol'-Janssen Injektionslösung 5 mg/ml. http://www.fachinfo.de. Zugegriffen 01.07.2013

  39. Arzneimittelkommission der deutschen Ärzteschaft (2010) Drug Safety Mall 2010-098 vom 05.05.2010. Arzneimittelkommission der deutschen Ärzteschaft, Berlin

    Google Scholar 

  40. Biedler A, Helfen C, Pajonk FG (2012) Behandlungsbedürftigkeit psychiatrischer Notfälle Im Notarztdienst. Evaluierung des „Indikator für psychiatrische Pharmakotherapie". Anaest- hesist 61:116–122

    Google Scholar 

  41. Tonn P, Reuter S, Treder B et al (2004) Die präklinische Behandlung von akut erregten, deliranten oder psychotischen Patienten durch den Notarzt. Notfall Rettungsmed 7:484–492

    Article  Google Scholar 

  42. Brown TM, Skop BR Mareth TR (1996) Pathophysiology and management of the serotonin syndrome. Ann Pharmacother 30:527-533 Kotlyar M, Dysken M, Adson DE (2005) Update on drug-induced depression in the elderly. Am J Geriatr Pharmacother 3:288–300

    Google Scholar 

  43. Kotlyar M, Dysken M, Adson OE (2OOS) Update on drug-induced depression in the elderiy. Am J Geliatr Pharmacother- 3:283–300

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie Universitätsklinikum, Universitätsklinikum des Saarlandes, Saarlandes Kirrberger Straße, 100 66421, Homburg/Saar

    A. Wolf

  2. Vitos Klinikum Gießen-Marburg, Gießen

    M J. Müller

  3. Klinik für Psychiatrie und Psychotherapie, Georg-August-Unlversität Göttingen, Göttingen

    F.-G.B. Pajonk

Authors
  1. A. Wolf
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. M J. Müller
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. F.-G.B. Pajonk
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Klinik für Innere Medizin, St. Antonius-Hospital, Dechant-Deckers-Str. 8, 52249, Eschweiler

    U. Janssens

  2. Univ.-Klinik für Innere Medizin I, Universitätsklinikum Innsbruck, Aichstr. 35, A-6020, Innsbruck

    M. Joannidis

  3. Med. Klinik und Poliklinik II, Universitätsklinikum Gießen, Klinikstr. 36, 35392, Gießen

    K. Mayer

Rights and permissions

Reprints and permissions

Copyright information

© 2015 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Wolf, A., Müller, M., Pajonk, FG. (2015). Psychopharmakotherapie im Notarztdienst. In: Janssens, U., Joannidis, M., Mayer, K. (eds) Weiterbildung Intensivmedizin und Notfallmedizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-46521-9_3

Download citation

  • DOI: https://doi.org/10.1007/978-3-662-46521-9_3

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-46520-2

  • Online ISBN: 978-3-662-46521-9

  • eBook Packages: Medicine (German Language)

Publish with us

Policies and ethics

Search

Navigation