Zusammenfassung
Die Thrombose zerebraler und duraler Hirnvenen kann durch die Erhöhung des intrakraniellen Druckes zu lebensbedrohlichen Zuständen führen. Eine rechtzeitige Diagnosestellung und Einleitung einer Therapie ist daher von größter Wichtigkeit. Auch die idiopathische intrakranielle Drucksteigerung geht mit einer Erhöhung des intrakraniellen Druckes einher. Die Diagnose ist eine Ausschlussdiagnose. Bei Patientinnen in Schwangerschaft und Wochenbett sind neurologisch-intensivmedizinische Komplikationen grundsätzlich selten. Da sie aber oft schwerwiegend sind und Schwangere sowie ungeborenes oder neugeborenes Kind gleichzeitig gefährden, haben sie eine große Bedeutung. Das gleichzeitige Betroffensein zweier Menschen bei einer Erkrankung macht die neurologisch-intensivmedizinische Behandlung Schwangerer zu einer besonderen Angelegenheit.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Literatur
Zu 30.1
Ahn TB, Roh JK (2003) A case of cortical vein thrombosis with the cord sign. Arch Neurol 60:1314–1316
Baumgartner RW, Studer A, Arnold M, Georgiadis D (2003) Recanalisation of cerebral venous thrombosis. J Neurol Neurosurg Psychiatry 74:459–461
Bruce BB, Kedar S, Van Stavern GP, Monaghan D, Acierno MD, Braswell RA, Preechawat P, Corbett JJ, Newman NJ, Biousse V (2009) Idiopathic intracranial hypertension in men. Neurology 72:304–309
Bruce BB, Kedar S, Van Stavern GP, Corbett JJ, Newman NJ, Biousse V (2010) Atypical idiopathic intracranial hypertension: normal BMI and older patients. Neurology 74:1827–1832
Bugnicourt JM, Guegan-Massardier E, Roussel M et al (2013) Cognitive impairment after cerebral venous thrombosis: a two-center study. J Neurol 260:1324–1331
Canhao P, Ferro JM, Lindgren AG, Bousser MG, Stam J, Barinagarrementeria F, ISCVT Investigators (2005) Causes and predictors of death in cerebral venous thrombosis. Stroke 36:1720–1725
Canhão P, Cortesão A, Cabral M, Ferro JM, Stam J, Bousser MG, Barinagarrementeria F, Investigators ISCVT (2008) Are steroids useful to treat cerebral venous thrombosis? Stroke 39:105–110
Celebisoy N, Gökçay F, Sirin H, Akyürekli O (2007) Treatment of idiopathic intracranial hypertension: topiramate vs. acetazolamide, an open-label study. Acta Neurol Scand 116:322–327
Coutinho JM, Ferro JM, Canhão P, Barinagarrementeria F, Cantú C, Bousser MG, Stam J (2009) Cerebral venous and sinus thrombosis in women. Stroke 40:2356–2361
Coutinho JM, Ferro JM, Canhão P, Barinagarrementeria F, Bousser MG, Stam J; Investigators ISCVT (2010) Unfractionated or low-molecular weight heparin for the treatment of cerebral venous thrombosis. Stroke 41:2575–2580
De Bruijn SF, Stam J (1999) Randomized, placebo-controlled trial of anticoagulant treatment with low-molecular-weight heparin for cerebral sinus thrombosis. Stroke 30:484–488
Einhäupl KM, Villringer A, Meister W, Mehraein S, Garner C, Pellkofer M, Haberl RL, Pfister HW, Schmiedek P (1991) Heparin treatment in sinus venous thrombosis. Lancet 338:597–600
Einhäupl K, Bousser MG, de Bruijn SF, Ferro JM, Martinelli I, Masuhr F, Stam J (2006) EFNS guideline on the treatment of cerebral venous and sinus thrombosis. Eur J Neurol 13:553–559
Ferro JM, Correia M, Rosas MJ, Pinto AN, Neves G, Cerebral Venous Thrombosis Portuguese Collaborative Study Group [Venoport] (2003) Seizures in cerebral vein and dural sinus thrombosis. Cerebrovasc Dis 15:78–83
Ferro JM, Canhao P, Stam J, Bousser MG, Barinagarrementeria F, ISCVT Investigators (2004) Prognosis of cerebral vein and dural sinus thrombosis: results of the International Study on Cerebral Vein and Dural Sinus Thrombosis (ISCVT). Stroke 35:664–670
Ferro JM, Canhao P, Bousser MG, Stam J, Barinagarrementeria F, ISCVT Investigators (2005) Cerebral vein and dural sinus thrombosis in elderly patients. Stroke 36:1927–1932
Ferro JM, Canhão P, Bousser MG, Stam J, Barinagarrementeria F; Investigators ISCVT (2008) Early seizures in cerebral vein and dural sinus thrombosis: risk factors and role of antiepileptics. Stroke 39:1152–1158
Ferro JM, Canhão P, Bousser MG, Stam J, Barinagarrementeria F, Stolz E, ISCVT Investigators (2010) Cerebral venous thrombosis with nonhemorrhagic lesions: clinical correlates and prognosis. Cerebrovasc Dis 29:440–445
Ferro JM1, Crassard I, Coutinho JM, et al.; Second International Study on Cerebral Vein and Dural Sinus Thrombosis (ISCVT 2) Investigators (2011) Decompressive surgery in cerebrovenous thrombosis: a multicenter registry and a systematic review of individual patient data. Stroke 42: 2825–2831
Frey JL, Muro GJ, McDougall CG, Dean BL, Jahnke HK (1999) Cerebral venous thrombosis: combined intrathrombus rtPA and intravenous heparin. Stroke 30:489–494
Friedman DI, Liu GT, Digre KB (2013) Revised diagnostic criteria for the pseudotumor cerebri syndrome in adults and children. Neurology 81:1159–1165
Geisbüsch C, Lichy C, Richter D, Herweh C, Hacke W, Nagel S (2014) Clinical course of cerebral sinus venous thrombosis. Data from a monocentric cohort study over 15 years. Nervenarzt 85:211–220
Girot M, Ferro JM, Canhao P, Stam J, Bousser MG, Barinagarrementeria F, Leys D; Investigators ISCVT (2007) Predictors of outcome in patients with cerebral venous thrombosis and intracerebral hemorrhage. Stroke 38:337–342
Gosk-Bierska I, Wysokinski W, Brown RD, Karnicki K, Grill D, Wiste H, Wysokinska E, McBane RD (2006) Cerebral venous sinus thrombosis: Incidence of venous thrombosis recurrence and survival. Neurology 67:814–819
Kim SY, Suh JH (1997) Direct endovascular thrombolytic therapy for dural sinus thrombosis: infusion of alteplase. AJNR Am J Neuroradiol 18:639–645
Miranda B, Ferro JM, Canhão P, Stam J, Bousser MG, Barinagarrementeria F, Scoditti U; Investigators ISCVT (2010) Venous thromboembolic events after cerebral vein thrombosis. Stroke 41:1901–1906
Pagan FL, Restrepo L, Balish M, Patwa HS, Houff S (2002) A new drug for an old condition? Headache 42:695–696
Palacio E, Rodero L, Pascual J (2004) Topiramate-responsive headache due to idiopathic intracranial hypertension in Behçet syndrome. Headache 44:436–437
Schwarz S, Daffertshofer M, Schwarz T, Georgiadis D, Baumgartner RW, Hennerici M, Groden C (2003) Aktuelle Probleme der Diagnose und Therapie zerebralen Venen- und duraler Sinusthrombosen. Nervenarzt 74:639–653
Shaikh AG, Bates JH, Yeates SW, Katirji B, Devereaux MW (2013) Fulminant idiopathic intracranial hypertension. JAMA Neurol 70:937–938
Sinclair AJ, Burdon MA, Nightingale PG, Ball AK, Good P, Matthews TD, Jacks A, Lawden M, Clarke CE, Stewart PM, Walker EA, Tomlinson JW, Rauz S (2010) Low energy diet and intracranial pressure in women with idiopathic intracranial hypertension: prospective cohort study. BMJ 341:c2701 doi:10.1136/bmj.c2701
Skau M, Brennum J, Gjerris F, Jensen R (2006) What is new about idiopathic intracranial hypertension? An updated review of mechanism and treatment. Cephalalgia 26:384–399
Stam J, De Bruijn SF, DeVeber G (2002) Anticoagulation for cerebral sinus thrombosis. Cochrane Database Syst Rev 4:CD002005
The International Classification of Headache Disorders, 2nd ed (2004) Cephalgia 24 (Suppl 1): 9–160
Zu 30.2
Bateman BT, Schumacher HC, Bushnell CD, Pile-Spellman J, Simpson LL, Sacco RL, Bernan MF (2006) Intracerebral hemorrhage in prgenancy. Neurology 67:424–429
Belfort MA, Anthony J, Saade GR, Allen JC, for the nimodipine study group (2003) A comparison of magnesium sulfate and nimodipine for the prevention of eclampsia. NEJM 348:304–311
Brewer J, Owens MY, Wallace K, Reeves AA, Morris R, Khan M, LaMarca B, Martin JN (2013) Posterior reversible encephalopythy syndrome in 46 of 47 patients with eclampsia. Am J Obstet Gynecol 208:468
Bousser M-G, Russel RR (1997) Cerebral venous thrombosis. Saunders, London, Philadelphia, Toronto, Sidney, Tokyo
Brown CE, Purdy P, Cunningham FG (1988) Head computed tomographic scans in women with eclampsia. Am J Obstet Gynecol 159:915–920
Chan LYS, Hang-Yuet M, Leung TN (2004) Guillan-Barre syndrome in pregnancy. Acta Obstet Gyn Scand 83:319–323
Cronin CA, Weisman CJ, Llinas RH (2008) Stroke treatment: beyond the three-hours window and in the pregnant patient. Ann N Y Acad Sci 1142:159–178
Devinsky O, Feldmann E, Hainline B (1994) Neurological complications of pregnancy Advances in Neurology, Bd. 64. Raven Press, New York
Digre KB, Varner MW (1993) Diagnosis and treatment of cerebrovascular dissorders in pregnancy. In: Adams HP Jr. (Hrsg) Handbook of cerebrovascular diseases. Marcel Dekker, New York, Basel, S 255–286
Druislane FW, Wang A-M (1997) Multifocal cerebral hemorrhage in eclampsia and severe pre-eclampsia. J Neurol 244:194–198
Duckitt K, Harrington D (2005) Risk factors for pre-eclampsia at antenatal booking: systematic review of controlled studies. BMJ 330:565–567. doi:doi:10.1136/bmj.38380.674340.E0
Easterling TR, Benederti TJ, Schmucker BC et al (1990) Maternal hemodynamics in normal and preeclamptic pregnancies: a longitudinal study. Obstet Gynecol 76:1061–1069
Eclampsia trial collaborative group (1995) Which anticonvulsant for women with eclampsia? Evidence from the collaborative eclampsia trial. Lancet 345:1455–1463
Edlow JA, Caplan LR, O`Brien K, Tibbles CD (2013) Diagnosis of acure neurological emergencies in pregnant and postpartum women. Lancet Neurol 12:175–185
Ferrero S, Pretta S, Nicoletti A, Petrera P, Ragni N (2005) Myasthenia gravis: management issues during pregnancy. Eur J Obstet Gyn Reprod Bio 121:129–138
Bewley S, Rudd A, Foo L (2013) Maternal death from stroke: a thirty year national retrospective review. Eur J Obstet Gynecol Reprod Biol L1(171):266–270
Fugate JE, Ameriso SF, Ortiz G et al (2012) Variable presentations of postpartum angiopathy. Stroke 43:670–676
Geocadin RG, Razumovsky AY, Wityk RJ, Bhardwaj A, Ulatowski JA (2003) Intracerebral hemorrhage and postpartal cerebral vasculopathy. J Neurol Sci 203:29–34
Gilmore J, Pennell PB, Stern BJ (1998) Medication use during pregnancy for neurologic conditions. Neurol Clin 16:189–205
Harden CL, Hopp J, Ting TY et al (2009) Practice parameter update: management issues for women with epilepsy – focus on pregnancy (an evidence-based review): obstetrical complications and change in seizure frequency. Neurology 73:126–132
James AH (2010) Pregnancy and thrombotic risk. Crit Care Med 38:57–S63
Janssens E, Hommel M, Mounier-Vehier F, Leclerc X, Guerin du Masgenet B, Leys D (1995) Postpartum cerebral angiopathy possibly to bromocriptine therapy. Stroke 26:128–130
Jilma B, Kamath S, Lip GYH (2003) Antithrombotic therapy in special circumstances. I- pregnancy and cancer. BMJ 326:37–40
Joseph P (2013) Broderick. Should Intravenous Thrombolysis be Considered the First Option in Pregnant Women? Stroke 44:866–867
Jung S-Y, Bac H-J, Park B-J, Yoon BW, on behalf of the acute brain bleeding analysis study group (2010) Parity and the risk of hemorrhagic strokes. Neurology 74:1424–1429
Karnard DR, Guntupelli KK (2005) Neurologic disorders in pregnancy. Crit Care Med 33:362–371
Kaplan PW (1995) Concepts of epilepsy care and pregnancy. In: Neurological problems in pregnant women. American Academy of Neurology, Seattle
Kittner SJ, Stern BJ, Feeser BR et al (1996) Pregnancy and stroke. N E J M 335:768–774
Kittner SJ (1997) Reply, Letter to the Editor. N E J M 336:665
Kupferminc MJ, Yair D, Bornstein NM, Lessing JB, Eldor A (2000) Transient focal neurological deficits during pregnancy in carriers of inherited thrombophilia. Stroke 31:892–895
Lamy C, Hamon JB, Coste J, for the French study group on stroke in pregnancy (2000) Ischemic stroke in young women. Neurology 55:269–274
Lansak DL, Kryscio RJ (2000) Risk factors for peripartum and postpartum stroke and intracranial venous thrombosis. Stroke 31:1274–1282
Zeng X, Hussain M, Meng R, Liu Y, Yuan K, Sikharam C, Ding Y, Ling F, Ji X, Li G (2013) Safety and validity of mechanical thrombectomy and thrombolysis on severe cerebral venous sinus thrombosis. Neurosurgery G1(72):730–738
Lukas MJ, Leveno KI, Cunningham FG (1995) Comparison of magnesium sulfate with phenytoine for the prevention of eclampsia. N E J M 333:201–205
Marugappan A, Coplin WM, Al-Sadat AN, McAllen KJ, Schwamm LH, Wechsler LR, KidwellCS, Saver JL, Starkman S, Gobin YP, DuckwilerG, Krueger M, Rordorf G, Broderick JP, Tietjen GE, Levine SR (2006) Thrombolytic therapy in acute ischemic stroke during pregnancy. Neurology 66:768–770
Pasternak B, Hviid A (2010) Use of acyclovir, valacyclovir, and famciclovir in the first trimester of pregnancy and the risk of birth defects. JAMA 304:859–866
Poser S (1998) Schwangerschaft bei neurologischen Erkrankungen. Akt Neurol 25:133–138
Rappaport VJ, Hirata G, Kim YH et al (1990) Antivascular endothelial cell antibodies in severe preeclampsia. Am J Obstet Gynecol 162:138–143
Raps EC, Galetta SL, Flamm ES (1994) Neurointensive care of the pregnant woman. Neurol Clin 12:601–612
Raroque HG, Orrison WW, Rosenberg GA (1990) Neurologic involvement in toxemia of pregnancy: Reversibel MRI lesions. Neurology 40:167–169
Rath WH, Hofer S, Sinicina I (2014) Fruchtwasserembolie – eine interdisziplinäre Herausforderung: Epidemiologie, Diagnostik und Therapie. Dtsch Arztebl Int 111:126–132. doi:10.3238/arztebl.2014.0126
Roenning OM, Dahl A, Bakkes SJ, Hussain AI, Dzilkas EA (2010) Stroke in the Puerperium treated with intraarterial rt-PT. JNNP 81:585–586
Sawle GV, Ramsay MM (1998) The neurology of pregnancy. J Neurol Neurosurg Psychiatry 64:711–725
Schobel HP, Fischer T, Heuszer K, Geiger H, Schmieder RE (1996) Preeclampsia- a state of sympathetic overactivity. NEJM 335:1480–1485
Sextro F, Klimpe S, Hamann GF (2013) Schwangerschaftsassoziierte Endotheliopathie – Eine Erkrankung mit multiplen Varianten? Nervenarzt 83:510–513
Sibai BM, Schneider JM, Morrison JC et al (1980) The late postpartum eclampsia controversy. Obstet Gynecol 55:75–78
Sibai BM (1991) Immunologic aspects of preeclampsia. Clin Obstet Gynecol 34:27–33
Sibai B, Kupferminc M (2005) Pre-eclampsia. Lancet 365:785–799
Skilton MR, Bonnet F, Begg LM, Juonala M, Kähönen M, Lehtimäki T, Viikari JSA, Raitakari OT (2010) Childbearing, Child-Rearing, Cardiovascular risk factors, and progression of carotid intima-media thickness: the cardiovascular risk in Young Finns study. Stroke 41:1332–1337
Steegers EA, von Dadelszen P, Duvekot JJ, Pijnenborg R (2010) Pre-eclampsia. Lancet 376:631–644
Stevens CJ, Heran MKS (2012) The many faces of posterior reversible encephalopathy syndrome. Br J Radiol 85:1566–1575
Stocks G (2014) Preeclampsia: pathophysiology, old and new strategies for management. Eur J Anaesthesiol 31:183–189
Striano P, Striano S, Tortora F, de Robertis E, Palumbo D, Elefante A, Servillo G (2005) Clinical spectrum and critical care management of persterior reversible encephalopathy syndrome (PRES). Med Sci Monit 11:R549–553
Turrentine MA, Braems G, Ramirez MM (1995) Use of thrombolytics for the treatment of thromboembolic disease during pregnancy. Obstet Gynecol Surv 50:534–541
Toglia MR, Weg JG (1996) Venous thromboembolism during pregnancy. N Engl J Med 335:108–114
Uzan J, Carbonnel M, Piconne-O et al (2011) Preeclampsia: pathophysiology, diagnosis and management. Vasc Health Risk Manag 7:467–474
Yerby MS, Devinsky O (1994) Neurologic complications of pregnancy. Neurol Clin 12:443–655
Young GB (1998) The maternity ward. In: Young GB, Ropper R, Bolten V (Hrsg) Coma. Mc Graw-Hill, New York
Wagner SJ, Acquah LA, Lindell EP et al (2011) Posterior reversible encephalopathy syndrome and eclampsia: pressing the case for more aggressive blood pressure control. Mayo Clin Proc 86:851–856
Wiese KM, Talkad A, Mathews M, Wang D (2006) Intravenous recombinant tissue plasminogen activator in a pregnant woman with cardioembolic stroke. Stroke 37:2168–2169
Wilterdink JL, Easton JD (1994) Cerebral ischemia and cerebral hemorrhage. In: Devinsky O, Feldmann E, Hainline B (Hrsg) Neurological complications of pregnancy. Advances in Neurology, Bd. 64. Raven Press, New York, S 1–24
Wilterdink JL, Feldmann E (2002) Intracranial hemorrhage. In: Hainline B, Devinsky O (Hrsg) Neurological complications of pregnancy, 2. Aufl. Lippincott Williams Wilkins, Baltimore, S 63–74
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2015 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Mäurer, M., Hamann, G.F., Liebetrau, M. (2015). Sinusthrombose. In: Schwab, S., Schellinger, P., Werner, C., Unterberg, A., Hacke, W. (eds) NeuroIntensiv. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-46500-4_30
Download citation
DOI: https://doi.org/10.1007/978-3-662-46500-4_30
Published:
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-662-46499-1
Online ISBN: 978-3-662-46500-4
eBook Packages: Medicine (German Language)