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Variation, Genetics, and Evolution of the Primate Craniofacial Complex

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Genome Mapping and Genomics in Human and Non-Human Primates

Part of the book series: Genome Mapping and Genomics in Animals ((MAPPANIMAL,volume 5))

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Abstract

The primate craniofacial complex is characterized by tremendous variation in size and configuration. This variation has played an important role in evolutionary inquiries, as the craniofacial skeleton, along with the dentition, provides the primary basis for phylogenetic assessments of fossil specimens. Numerous studies have explored the functional influences and constraints associated with the craniofacial complex, which have significance in biomedical applications, but there are relatively few inquiries into the genetic underpinnings of this important anatomy in nonhuman primates. This chapter describes efforts to characterize the genetic influences on the craniofacial complex in animal models in general, and in humans and nonhuman primates. The evolutionary biology and biomedical significance of these studies are explored.

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Acknowledgments

The craniofacial research program at Wright State University is funded by the National Institute for Dental and Craniofacial Research, National Institutes of Health (DE016692, DE016408, and DE018497 to RJ Sherwood, NIH grant P51 RR13986 to the Southwest National Primate Research Center).

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Authors and Affiliations

  1. Division of Morphological Sciences and Biostatistics, Department of Community Health, Department of Pediatrics, Boonshoft School of Medicine, Wright State University, 3171 Research Blvd, Kettering, OH, 45420, USA

    Richard J. Sherwood

  2. Division of Morphological Sciences and Biostatistics, Department of Community Health, Department of Orthopaedic Surgery, Boonshoft School of Medicine, Wright State University, Kettering, OH, 45420, USA

    Dana L. Duren

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Correspondence to Richard J. Sherwood .

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  1. South Texas Diabetes and Obesity Institute, University of Texas Health Science Center at San Antonio, Edinburg, Texas, USA

    Ravindranath Duggirala

  2. South Texas Diabetes and Obesity Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA

    Laura Almasy

  3. South Texas Diabetes and Obesity Institute, Brownsville, Texas, USA

    Sarah Williams-Blangero

  4. Faculty of Biomedical Sciences, Technology & Research, Sri Ramachandra University, Chennai, India

    Solomon F.D. Paul

  5. Bidhan Chandra Krishi Viswavidyalaya, Mohanpur, West Bengal, India

    Chittaranjan Kole

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Sherwood, R.J., Duren, D.L. (2015). Variation, Genetics, and Evolution of the Primate Craniofacial Complex. In: Duggirala, R., Almasy, L., Williams-Blangero, S., Paul, S., Kole, C. (eds) Genome Mapping and Genomics in Human and Non-Human Primates. Genome Mapping and Genomics in Animals, vol 5. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-46306-2_14

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