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Praktische Bioinformatik

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Methoden der Bioinformatik

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Zusammenfassung

In Kap. 2 bildeten die unbehandelten, elementaren Sequenzdaten den Ausgangspunkt und es wurde versucht, Schritt für Schritt mit immer fortgeschritteneren mathematischen Methoden Informationen aus diesen Daten zu extrahieren. In diesem Kapitel kehrt sich diese Blickrichtung um. Nun werden wir vielfach etablierte Analysemethoden und Betrachtungsweisen in den Vordergrund stellen, um dann hinter die Kulissen dieser Methoden zu schauen und die dort wirksamen mathematischen Verfahren zu entdecken und zu verstehen. Den Anfang bilden Verfahren des Sequenzvergleichs, gefolgt von phylogenetischen Analysen, die ähnliche Sequenzsegmente aufgrund der quantifizierten Unterschiede zwischen den Segmenten in einen kausalen Zusammenhang bringen. Am Ende steht eine Diskussion bioinformatischer Datenbanken.

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Author information

Authors and Affiliations

  1. Dep. of Life Sciences and Chemistry, Jacobs University Bremen, Bremen, Deutschland

    Marc-Thorsten Hütt

  2. Fak. Biotechnologie und Bioinformatik, Hochschule Weihenstephan-Triesdorf, Freising, Deutschland

    Manuel Dehnert

Authors
  1. Marc-Thorsten Hütt
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  2. Manuel Dehnert
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Correspondence to Marc-Thorsten Hütt .

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Hütt, MT., Dehnert, M. (2016). Praktische Bioinformatik. In: Methoden der Bioinformatik. Springer Spektrum, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-46150-1_3

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