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Influence of Scan Duration on the Reliability of Resting-State fMRI Regional Homogeneity

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Part of the book series: Communications in Computer and Information Science ((CCIS,volume 484))

Abstract

Regional homogeneity (ReHo) is widely used in the analysis of fMRI data of patients with schizophrenia. However, the influence of scan duration on the results is not clear. In this work, intraclass correlation coefficient (ICC) was applied to investigate the reliability of a popular method called KCC-ReHo algorithm, using rest-state fMRI data of schizophrenia patients. The full length 6 minutes data collected was split into data with six different durations from 1 min to 6 min with 1 min equal separation. With increasing scan duration, the mean ICC value of the whole brain is found to increase monotonically from 0.55 to 0.97, and the standard deviation decreases from 0.21 to 0.02. The high ICC values mainly occurred in the superior parietal gyrus, paracentral lobule, superior frontal gyrus dorsolateral, supplementary motor area, fusiform gyrus and inferior temporal gyrus of both hemispheres.

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Li, X., Zhou, J., Liu, X. (2014). Influence of Scan Duration on the Reliability of Resting-State fMRI Regional Homogeneity. In: Li, S., Liu, C., Wang, Y. (eds) Pattern Recognition. CCPR 2014. Communications in Computer and Information Science, vol 484. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-45643-9_42

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  • DOI: https://doi.org/10.1007/978-3-662-45643-9_42

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-45642-2

  • Online ISBN: 978-3-662-45643-9

  • eBook Packages: Computer ScienceComputer Science (R0)

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