Skip to main content

Abstract

Hyperhidrosis is excessive sweating which goes beyond the normal physiological reaction that occurs in response to fluctuations in temperature. Medical treatments include topical medication, iontophoresis, systemic anticholinergic medications and botulinum toxin injections.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 219.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 279.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Dumont P, Denoyer A, Robin P. Long term results of thoracoscopic sympathectomy for hyperhidrosis. Ann Thorac Surg. 2004;78(5):1801–7.

    Article  Google Scholar 

  • McAleer M, Collins P. A study investigating patient’s experience of hospital and home iontophoresis for hyperhidrosis. J Dermatology Treat. 2013. Epub ahead of print.

    Google Scholar 

  • Proebstle TM, Schneiders V, Knop J. Gravimetrically controlled efficacy of subcortical curettage: a prospective study for treatment of axillary hyperhidrosis. Dermatol Surg. 2002;28:1022e6.

    Google Scholar 

  • Rompel R, Scholz S. Subcutaneous curettage vs injection of botulinum toxin A for treatment of axillary hyperhidrosis. J Eur Acad Dermatol Venereol. 2001;15:207e11.

    Article  Google Scholar 

  • Streker M, Reuther T, Hagen L, Kerscher M. Hyperhidrosis plantaris - a randomised half side trial for efficacy and safety of an antiperspirant containing different concentrations of aluminium chloride. JDDG. 2012;10:115–9.

    PubMed  Google Scholar 

  • Togel B, Greve B, Raulin C. Current therapeutic strategies for hyperhidrosis: a review. Eur J Dermatol. 2002;12(3):219–23.

    PubMed  Google Scholar 

  • Wolosker N, De Campos JR, Kauffman P, Yazbek G, Neves S, Puech-Leao P. Use of oxybutynin for treating plantar hyperhidrosis. Int J Dermatol. 2013;52(5):620–3.

    Article  CAS  Google Scholar 

Further Reading

  • Ashton AC, Dolly JO. Characterization of the inhibitory action of botulinum neurotoxin type A on the release of several transmitters from rat cerebrocortical synaptosomes. J Neurochem. 1988;50:1808–16.

    Article  CAS  Google Scholar 

  • Bonerandi JJ, Lota I. La ionophorèse. Derm Prat. 1990;48:2–3.

    Google Scholar 

  • Collin J. Treating hyperhidrosis. Author’s reply. BMJ. 2000;321(16):702–3.

    PubMed Central  Google Scholar 

  • Collin J, Whatling P. Treating hyperhidrosis: surgery and botulinum toxin are treatments of choice in severe cases. BMJ. 2000;320(6):1221–2.

    Article  CAS  Google Scholar 

  • Desnos P, Corson N, Vigneron JL, Munoz MH, Bonerandi JJ. Traitement de l’hyperhidrose par ionophorèse: principe, matériel, méthodologie, résultats. A propos de 93 cas. Nouv Dermatol. 1988;7:551–4.

    Google Scholar 

  • Doft MA, Hardy KL, Ascherman JA. Treatment of hyperhidrosis with botulinum toxin. Aesthet Surg J. 2012;32(2):238–44.

    Article  Google Scholar 

  • Haxton HA. The sympathetic nerve supply of the upper limb in relation to sympathectomy. Ann R Coll Surg Engl. 1954;14:247–66.

    CAS  PubMed  PubMed Central  Google Scholar 

  • Holze E, Ruzicka T. Treatment of hyperhidrosis by a battery-operated iontophoretic device. Dermatologica. 1986;172:41–7.

    Article  Google Scholar 

  • Lee HH, Kim do W, Kim do W, Kim C. Efficacy of glycopyrrolate in primary hyperhidrosis patients. Kor J Pain. 2012;25(1):28–32.

    Article  CAS  Google Scholar 

  • Lin TS, Kuo SJ, Chou MC. Uniportal endoscopic thoracic sympathectomy for treatment of palmar and axillary hyperhidrosis: analysis of 2000 cases. Neurosurgery. 2002;51(5 Suppl):S84–7.

    PubMed  Google Scholar 

  • Mackenzie A, Burns C, Kavanagh G. Topical glycopyrrolate for axillary hyperhidrosis. Br J Dermatol. 2013;169(2):484–4.

    Google Scholar 

  • McWilliam SA, Montgomery I, Jenkinson DM, Elder HY, Wilson AM, Sutton MA. Effects of topically applied antiperspirant on sweat gland function. Br J Dermatol. 1987;120:907–8.

    Google Scholar 

  • Müller C, Berensmeier A, Hamm H, Dirschka T, Reich K, Fischer T, Rzany B. Efficacy and safety of methantheline bromide (Vagantin(®)) in axillary and palmar hyperhidrosis: results from a multicenter, randomized, placebo-controlled trial. J Eur Acad Dermatol Venereol. 2012;27(10):1278–84.

    Google Scholar 

  • Noel F, Pierard-Franchimont C, Pierard GE, Quatresoozi P. Sweaty skin, background and assessments. Int J Dermatol. 2012;51:647–55.

    Article  Google Scholar 

  • Odia S, Vocks E, Rakoski J, Ring J. Successful treatment of dyshidrotic hand eczema using tap water iontophoresis with pulsed direct current. Acta Derm Venereol. 1996;76:472–4.

    CAS  PubMed  Google Scholar 

  • Phadke VA, Joshi RS, Khopkar US, Wadhwa SL. Comparison of topical methenamine, glutaraldehyde and tap water iontophoresis for palmoplantar hyperhidrosis. Indian J Dermatol Venereol Leprol. 1995;61:346–8.

    CAS  PubMed  Google Scholar 

  • Reinauer S, Neusser A, Schauf G, Holzle E. Pulsed direct current iontophoresis as a possible new treatment for hyperhidrosis. Hautarzt. 1995;46:543–7.

    Article  CAS  Google Scholar 

  • Rowland Payne CME, Doe PT. Liposuction for axillary hyperhidrosis. Clin Exp Dermatol. 1998;23:9e10.

    Article  Google Scholar 

  • Shelley WB, Hurley HJ. Studies on topical antiperspirant control of axillary hyperhidrosis. Acta Derm Venereol. 1975;95:241–60.

    Google Scholar 

  • Shimizu H, Tamada Y, Shimizu J. Effectiveness of iontophoresis with alternating current (AC) in the treatment of patients with palmoplantar hyperhidrosis. J Dermatol. 2003;30:444–9.

    Article  Google Scholar 

  • Vorkamp T, Foo FJ, Khan S, Schmitto JD, Wilson P. Hyperhidrosis: evolving concepts and comprehensive review. Surgeon. 2010;8:287–92.

    Article  Google Scholar 

  • Walling HW, Swick BL. Treatment options for hyperhidrosis. Am J Clin Dermatol. 2011;12(5):285–95.

    Article  Google Scholar 

  • Worle B, Rapprich S, Heckmann M. Definition and treatment of primary hyperhidrosis. JDDG. 2007;5(7):625–8.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Benedetta Brazzini .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2015 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Brazzini, B., Sultan, S. (2015). Primary Hyperhidrosis. In: Katsambas, A.D., Lotti, T.M., Dessinioti, C., D’Erme, A.M. (eds) European Handbook of Dermatological Treatments. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-45139-7_43

Download citation

  • DOI: https://doi.org/10.1007/978-3-662-45139-7_43

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-45138-0

  • Online ISBN: 978-3-662-45139-7

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics