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Multimodality in Functional Neuroimaging

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Clinical Functional MRI

Part of the book series: Medical Radiology ((Med Radiol Diagn Imaging))

Abstract

The multimodal approach which is conceptually based on the combination of different noninvasive functional neuroimaging tools and their registration and co-integration into neuronavigational systems is widely used in presurgical diagnostics. In particular, the combination of imaging techniques that independently map different functional systems is a useful application, such as functional MRI (in its traditional task-related approach as well as in the increasingly used task-free intrinsic functional connectivity approach) as a technique for the localization of eloquent cortex and diffusion-tensor imaging as a method for the mapping of white matter fiber bundles/tracts. Magnetic source imaging as an additional imaging technique for cortical function mapping is of particular advantage in epilepsy surgery. Advanced functional pathoanatomy-based techniques such as nuclear medicine imaging (multi-ligand imaging) or MR spectroscopy might additionally be useful for the delineation of cerebral lesions (e.g., neoplasms). Although “multimodal imaging” may be complex in data acquisition and postprocessing, it is a valuable instrument to improve surgical planning and performance.

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Authors and Affiliations

  1. Department of Neurology, University of Ulm, Oberer Eselsberg 45, Ulm, 89081, Germany

    Jan Kassubek MD & Hans-Peter Müller PhD

  2. PET/CT Center NW-Switzerland, Claraspital Basel, Kleinriehenstr. 30, Basel, 4010, Switzerland

    Freimut D. Juengling MD

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  1. Jan Kassubek MD
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  3. Freimut D. Juengling MD
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Correspondence to Jan Kassubek MD .

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  1. Division of Diagnostic and Interventional Neuroradiology, University Hospitals Basel, Basel, Switzerland

    Christoph Stippich

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Kassubek, J., Müller, HP., Juengling, F.D. (2015). Multimodality in Functional Neuroimaging. In: Stippich, C. (eds) Clinical Functional MRI. Medical Radiology(). Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-45123-6_10

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