Skip to main content

Zusammenfassung

Durch die fast flächendeckende Anwendung bildgebender Diagnostik wie Ultraschall, Magnetresonanz- oder Computertomographie wird eine zunehmende Anzahl von Nierentumoren in einem frühen, lokal begrenzten, oft symptomlosen Stadium diagnostiziert. Aus bisherigen Beobachtungsstudien weiß man, dass diese kleinen, inzidenten Nierentumoren einerseits zwar in bis zu 87 % der Fälle maligne sind, andererseits jedoch meist nur sehr langsam wachsen und sehr selten metastasieren, weswegen auch diese Tumoren zunehmend nierenerhaltend operiert werden. Als Alternative stehen die folgenden bildgestützten, lokalablativen Verfahren zur Verfügung: Radiofrequenzablation, Kryoablation, bildgeführte interstitielle Hochdosisratenbrachytherapie sowie die Mikrowellenablation, die Laserablation und die Ablation durch hochintensiven, fokussierten Ultraschall. Alle Techniken sind entweder minimalinvasiv perkutan oder laparoskopisch anwendbar und weisen niedrigere Komplikationsraten als die Nierenteilresektion auf.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 69.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 89.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Literatur

Literatur zu Abschnitt 2.1

  • Arima K, Yamakado K, Kinbara H et al. (2007) Percutaneous radiofrequency ablation with transarterial embolization is useful for treatment of stage 1 renal cell carcinoma with surgical risk: results at 2-year mean follow up. Int J Urol 14:585-590; discussion 590

    Article  PubMed  Google Scholar 

  • Atwell TD, Schmit GD, Boorjian SA et al. (2013) Percutaneous ablation of renal masses measuring 3.0 cm and smaller: comparative local control and complications after radiofrequency ablation and cryoablation. AJR Am J Roentgenol 200:461–466

    Article  PubMed  Google Scholar 

  • Bosniak MA (1995) Observation of small incidentally detected renal masses. Semin Urol Oncol 13:267–272

    CAS  PubMed  Google Scholar 

  • Bosniak MA, Birnbaum BA, Krinsky GA et al. (1995) Small renal parenchymal neoplasms: further observations on growth. Radiology 197:589–597

    Article  CAS  PubMed  Google Scholar 

  • Bosniak MA, Krinsky GA, Waisman J (1995) Management of small incidental renal parenchymal tumors by watchful-waiting in selected patients based on observations of tumor growth rates. J Urol 1995:584–A

    Google Scholar 

  • Campbell SC, Novick AC, Belldegrun A et al. (2009) Guideline for management of the clinical T1 renal mass. J Urol 182:1271–1279

    Article  PubMed  Google Scholar 

  • Chang EL, Selek U, Hassenbusch SJ 3rd et al. (2005) Outcome Variation among »radioresistant« brain metastases treated with stereotactic radiosurgery. Neurosurgery 56:936-945; discussion 936–945

    Article  PubMed  Google Scholar 

  • Collettini F, Singh A, Schnapauff D, Powerski MJ, Denecke T, Wust P, Hamm B, Gebauer B (2013) Computed-tomography-guided high-dose-rate brachytherapy (CT-HDRBT) ablation of metastases adjacent to the liver hilum. Eur J Radiol 82(10):e509–514. doi: 10.1016/j.ejrad.2013.04.046. Epub 2013 Jun 21

    Article  Google Scholar 

  • Deschavanne PJ, Fertil B (1996) A review of human cell radiosensitivity in vitro. Int J Radiat Oncol Biol Phys 34:251-266

    Google Scholar 

  • DiBiase SJ, Valicenti RK, Schultz D et al. (1997) Palliative irradiation for focally symptomatic metastatic renal cell carcinoma: support for dose escalation based on a biological model. J Urol 158:746–749

    Google Scholar 

  • Dindo D, Demartines N, Clavien PA (2004) Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg 240:205–213

    Article  PubMed  PubMed Central  Google Scholar 

  • Frank I, Blute ML, Cheville JC et al. (2003) Solid renal tumors: an analysis of pathological features related to tumor size. J Urol 170:2217–2220

    Article  PubMed  Google Scholar 

  • Halperin EC, Harisiadis L (1983) The role of radiation therapy in the management of metastatic renal cell carcinoma. Cancer 51:614–617

    Article  CAS  PubMed  Google Scholar 

  • Henschke UK, Hilaris BS, Mahan GD (1964) Remote after-loading with intracavitary applicators. Radiology 83: 344–345

    Article  CAS  PubMed  Google Scholar 

  • Kunkle DA, Egleston BL, Uzzo RG (2008) Excise, ablate or observe: the small renal mass dilemma - a meta-analysis and review. J Urol 179:1227-1233; discussion 1233–1224

    Google Scholar 

  • Lee J, Hodgson D, Chow E et al. (2005) A phase II trial of palliative radiotherapy for metastatic renal cell carcinoma. Cancer 104:1894–1900

    Article  PubMed  Google Scholar 

  • Ljungberg B, Cowan NC, Hanbury, DC et al. (2010) EAU guide-lines on renal cell carcinoma: the 2010 update. Eur Urol 58:398–406

    Article  PubMed  Google Scholar 

  • Lounsberry W, Goldschmidt V, Linke CA et al. (1961) The early histologic changes following electrocoagulation. J Urol 86:321–329

    CAS  PubMed  Google Scholar 

  • Nakasone Y, Kawanaka K, Ikeda O et al. (2012) Sequential combination treatment (arterial embolization and percutaneous radiofrequency ablation) of inoperable renal cell carcinoma: single-center pilot study. Acta Radiol 53:410–414

    Article  PubMed  Google Scholar 

  • National Cancer Institute (NCI) (2009). Common Terminology Criteria for Adverse Events v4.0. NCI, NIH, DHHS. May 29, 2009. NIH publication # 09-7473

    Google Scholar 

  • Onufrey V, Mohiuddin M (1985) Radiation therapy in the treatment of metastatic renal cell carcinoma. Int J Radiat Oncol Biol Phys 11:2007–2009

    Google Scholar 

  • Orton CG, Ellis F (1973) A simplification in the use of the NSD concept in practical radiotherapy. Br J Radiol 46:529–537

    Article  CAS  PubMed  Google Scholar 

  • Park S, Strup SE, Saboorian H et al. (2006) No evidence of disease after radiofrequency ablation in delayed nephrectomy specimens. Urology 68:964–967

    Article  PubMed  Google Scholar 

  • Psutka SP, Feldman AS, McDougal WS et al. (2013) Long-term oncologic outcomes after radiofrequency ablation for T1 renal cell carcinoma. Eur Urol 63:486–492

    Article  PubMed  Google Scholar 

  • Rais-Bahrami S, Guzzo TJ, Jarrett TW et al. (2009) Incidentally discovered renal masses: oncological and perioperative outcomes in patients with delayed surgical intervention. BJU Int 103:1355–1358

    Article  PubMed  Google Scholar 

  • Remzi M, Marberger M (2009) Renal tumor biopsies for evaluation of small renal tumors: why, in whom, and how? Eur Urol 55:359–367

    Article  PubMed  Google Scholar 

  • Rendon RA, Kachura JR, Sweet JM et al. (2002) The uncertainty of radio frequency treatment of renal cell carcinoma: findings at immediate and delayed nephrectomy. J Urol 167:1587–1592

    Article  PubMed  Google Scholar 

  • Ricke J, Mohnike K, Pech M et al. (2010) Local response and impact on survival after local ablation of liver metastases from colorectal carcinoma by computed tomography-guided high-dose-rate brachytherapy. Int J Radiat Oncol Biol Phys 78:479–485

    Article  PubMed  Google Scholar 

  • Shannon BA, Cohen RJ, de Bruto H et al. (2008) The value of preoperative needle core biopsy for diagnosing benign lesions among small, incidentally detected renal masses. J Urol 180:1257-1261; discussion 1261

    Google Scholar 

  • Simmons MN, Weight CJ, Gill IS (2009) Laparoscopic radical versus partial nephrectomy for tumors 4 cm: intermediate-term oncologic and functional outcomes. Urology 73:1077–1082

    Article  PubMed  Google Scholar 

  • Stinauer MA, Kavanagh BD, Schefter TE et al. (2011) Stereotactic body radiation therapy for melanoma and renal cell carcinoma: impact of single fraction equivalent dose on local control. Radiat Oncol 6:3–4

    Article  Google Scholar 

  • Svedman C, Sandstrom P, Pisa P et al. (2006) A prospective phase II trial of using extracranial stereotactic radiotherapy in primary and metastatic renal cell carcinoma. Acta Oncol 45:870–875

    Article  PubMed  Google Scholar 

  • Takaki H, Nakatsuka A, Uraki J et al. (2013) Renal cell carcinoma: radiofrequency ablation with a multiple-electrode switching system - a phase II clinical study. Radiology 267:285–292

    Article  PubMed  Google Scholar 

  • Takaki H, Soga N, Kanda H et al. (2014) Radiofrequency ablation versus radical nephrectomy: clinical outcomes for stage T1b renal cell carcinoma. Radiology 270: 292–299

    Article  PubMed  Google Scholar 

  • Teh B, Bloch C, Galli-Guevara M et al. (2007) The treatment of primary and metastatic renal cell carcinoma (RCC) with image-guided stereotactic body radiation therapy (SBRT). Biomed Imaging Interv J 3:e–6

    Google Scholar 

  • Thompson RH, Atwell T, Schmit G et al. (2015) Comparison of Partial Nephrectomy and Percutaneous Ablation for cT1 Renal Masses. Eur Urol 67(2):252–259

    Article  PubMed  Google Scholar 

  • Tselis N, Chatzikonstantinou G, Kolotas C, Milickovic N, Baltas D, Zamboglou N (2013) Computed tomography-guided interstitial high dose rate brachytherapy for centrally located liver tumours: a single institution study. Eur Radiol 23(8):2264–2270. doi: 10.1007/s00330-013-2816-z. Epub 2013 Mar 21

    Article  PubMed  Google Scholar 

  • Van Poppel H, Da Pozzo, Albrecht W et al. (2007) A prospective randomized EORTC intergroup phase 3 study comparing the complications of elective nephron-sparing surgery and radical nephrectomy for low-stage renal cell carcinoma. Eur Urol 51:1606–1615

    Article  PubMed  Google Scholar 

  • Wagstaff P, Ingels A, Zondervan P et al. (2014) Thermal ablation in renal cell carcinoma management: a comprehensive review. Curr Opin Urol 24:474–482

    Article  PubMed  Google Scholar 

  • Wah TM, Irving HC, Gregory W et al. Radiofrequency ablation (RFA) of renal cell carcinoma (RCC): experience in 200 tumours. BJU Int 2014;113:416-428

    Google Scholar 

  • Wannenmacher M, Wenz F, Debus J (2013) Strahlentherapie. Springer, Heidelberg

    Book  Google Scholar 

  • Weight CJ, Kaouk JH, Hegarty NJ et al. (2008) Correlation of radiographic imaging and histopathology following cryoablation and radio frequency ablation for renal tumors. J Urol 179:1277-1281; discussion 1281–1273

    Article  Google Scholar 

  • Wieners G, Pech M, Rudzinska M et al. (2006) CT-guided interstitial brachytherapy in the local treatment of extrahepatic, extrapulmonary secondary malignancies. Eur Radiol 16:2586–2593

    Article  PubMed  Google Scholar 

  • Wieners G, Mohnike K, Peters N, Bischoff J, Kleine-Tebbe A, Seidensticker R, Seidensticker M, Gademann G, Wust P, Pech M, Ricke J (2011) Treatment of hepatic metastases of breast cancer with CT-guided interstitial brachytherapy-a phase II-study. Radiother Oncol 100(2):314–319. doi:10.1016/j.radonc.2011.03.005. Epub 2011 Apr 16

    Article  PubMed  Google Scholar 

  • Yamakado K, Nakatsuka A, Kobayashi S et al. (2006) Radiofrequency ablation combined with renal arterial embolization for the treatment of unresectable renal cell carcinoma larger than 3.5 cm: initial experience. Cardiovasc Intervent Radiol 29:389–394

    Article  PubMed  Google Scholar 

Literatur zu Abschnitt 2.2

  • Ball C, Thomson KR, Kavnoudias H (2010) Irreversible electroporation: a new challenge in »out of operating theater« anesthesia. Anesthesia & Analgesia 110:1305–1309

    Article  Google Scholar 

  • van den Bos W, de Bruin DM, Muller BG, Varkarakis IM, Karagiannis AA, Zondervan PJ, Laguna Pes MP, Veelo DP, Savci Heijink CD, Engelbrecht MR, Wijkstra H, de Reijke TM, de la Rosette JJ (2014) The safety and efficacy of irreversible electroporation for the ablation of prostate cancer: a multicentre prospective human in vivo pilot study protocol. BMJ Open 4(10):e006382. ClinicalTrials. gov database NCT01790451. https://clinicaltrials.gov/ct2/show/NCT01790451?term=NCT01790451&rank=1 . Zugegriffen: 25. März 2015

  • Davalos RV, Mir IL, Rubinsky B (2005) Tissue ablation with irreversible electroporation. Ann Biomed Eng 33(2):223–231

    Article  CAS  PubMed  Google Scholar 

  • Deodhar A, Monette S, Single GW Jr, Hamilton WC Jr, Thornton R, Maybody M, Coleman JA, Solomon SB (2011) Renal tissue ablation with irreversible electroporation: preliminary results in a porcine model. Urology 77(3): 754–760

    Article  PubMed  Google Scholar 

  • Faroja M, Ahmed M, Appelbaum L, Ben-David E, Moussa M, Sosna J, Nissenbaum I, Goldberg SN (2013) Irreversible electroporation ablation: is all the damage nonthermal? Radiology 266(2):462–470

    Article  PubMed  Google Scholar 

  • Fornara P, Doehn C, Friedrich HJ, Jocham D (2001) Nonrandomized comparison of open flank versus laparoscopic nephrectomy in 249 patients with benign renal disease. Eur Urol 40(1):24–31

    Article  CAS  PubMed  Google Scholar 

  • Gunn AJ, Gervais DA (2014) Percutaneous ablation of the small renal mass-techniques and outcomes. Semin Intervent Radiol 31(1):33–41

    Article  PubMed  PubMed Central  Google Scholar 

  • Ladd AP, Rescorla FJ, Baust JG, Callahan M, Davis M, Grosfeld JL (1999) Cryosurgical effects on growing vessels. Am Surg 65(7):677–682

    CAS  PubMed  Google Scholar 

  • Lee EW, Wong D, Prikhodko SV, Perez A, Tran C, Loh CT, Kee ST (2012) Electron microscopic demonstration and evaluation of irreversible electroporation-induced nanopores on hepatocyte membranes. J Vasc Interv Radiol 23(1):107–113

    Google Scholar 

  • Liehr UB, Wendler JJ, Blaschke S, Porsch M, Janitzky A, Baumunk D, Pech M, Fischbach F, Schindele D, Grube C, Ricke J, Schostak M (2012) Irreversible electroporation: the new generation of local ablation techniques for renal cell carcinoma. Urologe A 51(12):1728–1734

    Google Scholar 

  • Ljungberg B, Cowan N, Hanbury DC, Hora M, Kuczyk MA, Merseburger AS, Mulders PFA, Patard JJ, Sinescu IC, European Association of Urology Group (2010) EAU guidelines on renal cell carcinoma: the 2010 update. Eur Urol 58(3):398–406

    Article  PubMed  Google Scholar 

  • Ljungberg B, Bensalah K, Bex A, Canfield S, Dabestani S, Hofmann F, Hora M, Kuczyk MA, Lam T, Marconi L, Merseburger AS, Mulders PFA, Powles T, Staehler M, Volpe A, Bex A (2015) EAU guidelines on renal cell carcinoma: 2014 update. Eur Urol. 2015 Jan 20. doi: 10.1016/j. eururo.2015.01.005

    Google Scholar 

  • Lu DS, Raman SS, Vodopich DJ, Wang M, Sayre J, Lassman C (2002) Effect of vessel size on creation of hepatic radiofrequency lesions in pigs: assessment of the »heat sink« effect. AJR Am J Roentgenol 178(1):47–51

    Article  PubMed  Google Scholar 

  • MacLennan S, Imamura M, Lapitan MC, Omar MI, Lam TB, Hilvano-Cabungcal AM, Royle P, Stewart F, MacLennan G, MacLennan SJ, Canfield SE, McClinton S, Griffiths TR, Ljungberg B, N'Dow J; UCAN Systematic Review Reference Group; EAU Renal Cancer Guideline Panel (2012) Systematic review of oncological outcomes following surgical management of localised renal cancer. Eur Urol 61(5):972–993

    Article  Google Scholar 

  • Neumann E, Schaeffer-Ridder M, Wang Y, Hofschneider PH (1982) Gene transfer into mouse lymphoma cells by electroporation in high electric fields. EMBO J 1: 841–845

    CAS  PubMed  PubMed Central  Google Scholar 

  • The National Institute for Health and Clinical Excellence (NICE) (2013) NICE-Guideline: irreversible electroporation for the treatment of renal cancer, S 1-22. http://www.nice.org.uk/guidance/IPG443 . Zugegriffen: 23. März 2015

  • Olweny EO, Kapur P, Tan YK, Park SK, Adibi M, Cadeddu JA (2013) Irreversible electroporation: evaluation of nonthermal and thermal ablative capabilities in the porcine kidney. Urology 81(3):679–684

    Article  PubMed  Google Scholar 

  • Pech M, Janitzky A, Wendler JJ et al. (2011) Irreversible electroporation of renal cell carcinoma: a first-in-man phase I clinical study. Cardiovasc Intervent Radiol 34:132–138

    Article  PubMed  Google Scholar 

  • Wendler JJ, Porsch M, Nitschke S, Köllermann J, Siedentopf S, Pech M, Fischbach F, Ricke J, Schostak M, Liehr UB (2015) A prospective phase 2a pilot study investigating focal percutaneous irreversible electroporation (IRE) ablation by NanoKnife in patients with localised renal cell carcinoma (RCC) with delayed interval tumour resection (IRENE trial). Contemp Clin Trials 43:10–19. doi: 10.1016/j. cct.2015.05.002. [Epub ahead of print]

    Article  CAS  PubMed  Google Scholar 

  • Schilling S, Schmid S, Jäger H, Ludwig M, Dietrich H, Toepfl S, Knorr D, Neidhart S, Schieber A, Carle R (2008) Comparative study of pulsed electric field and thermal processing of apple juice with particular consideration of juice quality and enzyme deactivation. J Agric Food Chem 56(12):4545–4554

    Article  CAS  PubMed  Google Scholar 

  • Sommer CM, Fritz S, Wachter MF, Vollherbst D, Stampfl U, Bellemann N, Gockner T, Mokry T, Gnutzmann D, Schmitz A, Knapp J, Longerich T, Kuhn-Neureuther C, Pereira PL, Kauczor HU, Werner J, Radeleff BA (2013) Irreversible electroporation of the pig kidney with involvement of the renal pelvis: technical aspects, clinical outcome, and three-dimensional CT rendering for assessment of the treatment zone. J Vasc Interv Radiol 24(12):1888–1897

    Article  PubMed  Google Scholar 

  • Sugar IP, Neumann E (1984) Stochastic model for electric field-induced membrane pores. Electroporation. Biophys Chem 19(3):211–225

    Article  CAS  PubMed  Google Scholar 

  • Tacke J (2007) Interventional oncology in urology. Radiologe 47(12):1089–1096

    Article  CAS  PubMed  Google Scholar 

  • Thomson KR, Cheung W, Ellis SJ et al. (2011) Investigation of the safety of irreversible electroporation in humans. J Vasc Interv Radiol 22:611–621

    Article  PubMed  Google Scholar 

  • Toepfl S, Mathys A, Heinz V, Knorr D (2006) Potenzial of high hydrostatic pressure and pulsed electric fields for energy efficient and environmentally friendly food processing. Food Rev Int 22:405–423

    Article  CAS  Google Scholar 

  • Tracy CR, Kabbani W, Cadeddu JA (2011) Irreversible electroporation (IRE): a novel method for renal tissue ablation. BJU Int 107(12):1982–1987

    Article  PubMed  Google Scholar 

  • Valerio M, Dickinson L, Ali A, Ramachandran N, Donaldson I, Freeman A, Ahmed HU, Emberton M (2014) A prospective development study investigating focal irreversible electroporation in men with localised prostate cancer: Nanoknife Electroporation Ablation Trial (NEAT). Contemp Clin Trials 39(1):57–65

    Article  PubMed  PubMed Central  Google Scholar 

  • Wendler JJ, Pech M, Porsch M, Janitzky A, Fischbach F, Buhtz P, Vogler K, Hühne S, Borucki K, Strang C, Mahnkopf D, Ricke J, Liehr UB (2012a) Urinary tract effects after multifocal nonthermal irreversible electroporation of the kidney: acute and chronic monitoring by magnetic resonance imaging, intravenous urography and urinary cytology. Cardiovasc Intervent Radiol 35(4):921–926

    Article  PubMed  Google Scholar 

  • Wendler JJ, Pech M, Blaschke S, Porsch M, Janitzky A, Ulrich M, Dudeck O, Ricke J, Liehr UB (2012b) Angiography in the isolated perfused kidney: radiological evaluation of vascular protection in tissue ablation by nonthermal irreversible electroporation. Cardiovasc Intervent Radiol 35(2):383–390

    Article  PubMed  Google Scholar 

  • Wendler JJ, Porsch M, Hühne S, Baumunk D, Buhtz P, Fischbach F, Pech M, Mahnkopf D, Kropf S, Roessner A, Ricke J, Schostak M, Liehr UB (2013) Short- and mid-term effects of irreversible electroporation on normal renal tissue: an animal model. Cardiovasc Intervent Radiol 36(2):512–520

    Article  CAS  PubMed  Google Scholar 

Literatur zu Abschnitt 2.3

  • Abreu SC, Gill IS (2003) Renal cell carcinoma: modern surgical approach. Curr Opin Urol 13:439–444

    Article  PubMed  Google Scholar 

  • Adams JB, Moore RG, Anderson JH, Strandberg JD, Marshall FF, Davoussi LR (1996) High-intensity focused ultrasound ablation of rabbit kidney tumors. J Endourol 10:71–75

    Article  CAS  PubMed  Google Scholar 

  • Anderson JK, Matsumoto E, Cadeddu JA (2005) Renal radiofrequency ablation: technique and results. Urol Oncology 23:355–360

    Article  Google Scholar 

  • Campbell SC, Krishnamurthi V, Chow G, Hale J, Myles J, Novick AC (1998) Renal cryosurgery: experimental evaluation of treatment parameters. Urology 52:29-33; discussion 33–34

    Article  Google Scholar 

  • Chosy SG, Nakada SY, Lee FT Jr, Warner TF (1998) Monitoring renal cryosurgery: predictors of tissue necrosis in swine. J Urol 159:1370–1374

    Article  CAS  PubMed  Google Scholar 

  • Chow WH, Devesa SS, Warren JL, Fraumeni JF Jr (1999) Rising incidence of renal cell cancer in the United States. JAMA 281:1628–1631

    Article  CAS  PubMed  Google Scholar 

  • Finley DS, Beck S, Box G, Chu W, Deane L, Vajgrt DJ et al. (2008) Percutaneous and laparoscopic cryoablation of small renal masses. J Urol 180:492-498; discussion 498

    Article  PubMed  Google Scholar 

  • Gervais DA, McGovern FJ, Arellano RS, McDougal WS, Mueller PR (2003) Renal cell carcinoma: clinical experience and technical success with radio-frequency ablation of 42 tumors. Radiology 226:417–424

    Article  PubMed  Google Scholar 

  • Gervais DA, Arellano RS, McGovern FJ, McDougal WS, Mueller PR (2005a) Radiofrequency ablation of renal cell carcinoma: part 2, lessons learned with ablation of 100 tumors. AJR 185:72–80

    Article  PubMed  Google Scholar 

  • Gervais DA, Arellano RS, Mueller PR (2005b) Percutaneous radiofrequency ablation of renal cell carcinoma. Eur Radiol 15:960–967

    Article  PubMed  Google Scholar 

  • Gervais DA, McGovern FJ, Arellano RS, McDougal WS, Mueller PR (2005c) Radiofrequency ablation of renal cell carcinoma: part 1, indications, results, and role in patient management over a 6-year period and ablation of 100 tumors. AJR 185:64–71

    Article  PubMed  Google Scholar 

  • Gettman MT, Bishoff JT, Su LM, Chan D, Kavoussi LR, Jarrett TW et al. (2001) Hemostatic laparoscopic partial nephrectomy: initial experience with the radiofrequency coagulation-assisted technique. Urology 58:8–11

    Article  CAS  PubMed  Google Scholar 

  • Gill IS, Matin SF, Desai MM, Kaouk JH, Steinberg A, Mascha E et al. (2003) Comparative analysis of laparoscopic versus open partial nephrectomy for renal tumors in 200 patients. J Urol 170:64–68

    Article  PubMed  Google Scholar 

  • Gill IS, Remer EM, Hasan WA, Strzempkowski B, Spaliviero M, Steinberg AP et al. (2005) Renal cryoablation: outcome at 3 years. J Urol 173:1903–1907

    Article  PubMed  Google Scholar 

  • Hacker A, Michel MS, Koehrmann KU (2003) Extracorporeal organotripsy for renal tumours. Curr Opin Urol 13:221–225

    Article  PubMed  Google Scholar 

  • Hacker A, Vallo S, Weiss C, Grobholz R, Alken P, Knoll T et al. (2005) Minimally invasive treatment of renal cell carcinoma: comparison of 4 different monopolar radiofrequency devices. Eur Urol 48:584–592

    Article  PubMed  Google Scholar 

  • Hacker A, Michel MS, Marlinghaus E, Kohrmann KU, Alken P (2005) Extracorporeally induced ablation of renal tissue by high-intensity focused ultrasound. BJU Int 97:779–785

    Article  Google Scholar 

  • Illing RO, Kennedy JE, Wu F, ter Haar GR, Protheroe AS, Friend PJ et al. (2005) The safety and feasibility of extracorporeal high-intensity focused ultrasound (HIFU) for the treatment of liver and kidney tumours in a Western population. Br J Cancer 93:890–895

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Jacomides L, Ogan K, Watumull L, Cadeddu JA (2003) Laparoscopic application of radio frequency energy enables in situ renal tumor ablation and partial nephrectomy. J Urol 169:49-53; discussion 53

    Article  PubMed  Google Scholar 

  • Jang TL, Wang R, Kim SC, Troe T, Pins MR, Nadler RB (2005) Histopathology of human renal tumors after laparoscopic renal cryosurgery. J Urol 173:720–724

    Article  PubMed  Google Scholar 

  • Janzen N, Zisman A, Pantuck AJ, Perry K, Schulam P, Belldegrun AS (2002) Minimally invasive ablative approaches in the treatment of renal cell carcinoma. Curr Urol Rep 3:13–20

    Article  PubMed  Google Scholar 

  • Johnson DB, Taylor GD, Lotan Y, Sagalowsky AI, Koenemann KS, Cadeddu JA (2003) The effects of radio frequency ablation on renal function and blood pressure. J Urol 170:2234–2236

    Article  PubMed  Google Scholar 

  • Johnson DB, Solomon SB, Su LM, Matsumoto ED, Kavoussi LR, Nakada SY et al. (2004) Defining the complications of cryoablation and radio frequency ablation of small renal tumors: a multi-institutional review. J Urol 172:874–877

    Article  PubMed  Google Scholar 

  • KlatteT, Mauermann J, Heinz-Peer G, Waldert M, Weibl P, Klingler HC, Remzi M (2011) Perioperative, oncological and functional outcomes of laparoscopic renal cryoablation and open partial nephrectomy: a matched pair analysis. J Endourol 25(6): 991–997

    Google Scholar 

  • Klingler HC, M Susani (2010) Focal therapy and imaging in prostate and kidney cancer. Renal biopsy protocols pre, post and after focal therapy. J Endourol 24(5):701–705

    Article  PubMed  Google Scholar 

  • Klingler HC, Marberger M, Mauermann J, Remzi M, Susani M (2005) »Skipping« is still a problem with radiofrequency ablation of small renal tumours. BJU Int 99:998–1001

    Article  Google Scholar 

  • Klingler HC, Susani M, Seip R, Mauermann J, Sanghvi N, Marberger MJ (2008) A novel approach to energy ablative therapy of small renal tumours: laparoscopic high-intensity focused ultrasound. Eur Urol 53: 810–816

    Article  PubMed  Google Scholar 

  • Krambeck AE, Farrell MA, Charboneau JW, Frank I, Zincke H (2005) Intraperitoneal drop metastasis after radiofrequency ablation of pararenal tumor recurrences. Urology 65:79–7

    Google Scholar 

  • Kunkle DA, Uzzo RG (2008) Cryoablation or radiofrequency ablation of the small renal mass: a meta-analysis. Cancer 113:2671–2680

    Article  PubMed  PubMed Central  Google Scholar 

  • Laguna MP, Beemster P, Kumar V, Klingler HC et al. (2009) Perioperative morbidity of laparoscopic cryoablation of small renal masses with ultrathin probes: a European multicentre experience. Eur Urol 56(2):355–361

    Article  PubMed  Google Scholar 

  • Lam JS, Shvarts O, Pantuck AJ (2004) Changing concepts in the surgical management of renal cell carcinoma. Eur Urol 45:692–705

    Article  PubMed  Google Scholar 

  • Lotan Y, Duchene DA, Cadeddu JA, Sagalowsky AI, Koeneman KS (2004) Changing management of organ-confined renal masses. J Endour 18:263–268

    Article  Google Scholar 

  • Marberger M, Schatzl G, Cranston D, Kennedy JE (2005) Extracorporeal ablation of renal tumours with high-intensity focused ultrasound. BJU Int 95 (Suppl 2):52–55

    Article  PubMed  Google Scholar 

  • Matlaga BR, Zagoria RJ, Woodruff RD, Torti FM, Hall MC (2002) Phase II trial of radio frequency ablation of renal cancer: evaluation of the kill zone. J Urol 168:2401–2405

    Article  PubMed  Google Scholar 

  • McDougal WS, Gervais DA, McGovern FJ, Mueller PR (2005) Long-term followup of patients with renal cell carcinoma treated with radio frequency ablation with curative intent. J Urol 174:61–63

    Article  PubMed  Google Scholar 

  • McGovern FJ, Wood BJ, Goldberg SN, Mueller PR (1999) Radio frequency ablation of renal cell carcinoma via image guided needle electrodes. J Urol 161:599–600

    Article  CAS  PubMed  Google Scholar 

  • Memarsadeghi M, Schmook T, Remzi M, Weber M, Potscher G, Lammer J et al. (2006) Percutaneous radiofrequency ablation of renal tumors: midterm results in 16 patients. Eur J Radiol 59:183–189

    Article  PubMed  Google Scholar 

  • Michaels MJ, Rhee HK, Mourtzinos AP, Summerhayes IC, Silverman ML, Libertino JA (2002) Incomplete renal tumor destruction using radio frequency interstitial ablation. J Urol 168:2406-2409; discussion 2409–2410

    Article  Google Scholar 

  • Murphy DP, Gill IS (2001) Energy-based renal tumor ablation: a review. Semin Urol Oncol 19:133–140

    CAS  PubMed  Google Scholar 

  • Novick AC (2004) Laparoscopic and partial nephrectomy. Clin Cancer Res 10:6322S–6327S

    Article  Google Scholar 

  • Novick AC, Derweesh I (2005) Open partial nephrectomy for renal tumours: current status. BJU Int 95(Suppl 2):35–40

    Article  PubMed  Google Scholar 

  • Ogan K, Jacomides L, Dolmatch BL, Rivera FJ, Dellaria MF, Josephs SC et al. (2002) Percutaneous radiofrequency ablation of renal tumors: technique, limitations, and morbidity. Urology 60:954–958

    Article  PubMed  Google Scholar 

  • Olweny EO, Park SK, Tan YK, Best SL, Trimmer C, Cadeddu JA (2012) Radiofrequency ablation versus partial nephrectomy in patients with solitary clinical T1a renal cell carcinoma: comparable oncologic outcomes at a minimum of 5 years of follow-up. Eur Urol 61:1156–1161

    Article  PubMed  Google Scholar 

  • Panumatrassamee K, Kaouk JH, Autorino R, Lenis AT, Laydner H, Isac W et al. (2013) Cryoablation versus minimally invasive partial nephrectomy for small renal masses in the solitary kidney: impact of approach on functional outcomes. J Urol 189:818–822

    Article  PubMed  Google Scholar 

  • Psutka SP, Feldman AS, McDougal WS, McGovern FJ, Mueller P, Gervais DA (2013) Long-term oncologic outcomes after radiofrequency ablation for T1 renal cell carcinoma. Eur Urol 63:486–492

    Article  PubMed  Google Scholar 

  • Rehman J, Landman J, Lee D, Venkatesh R, Bostwick DG, Sundaram C et al. (2004) Needle-based ablation of renal parenchyma using microwave, cryoablation, impedance- and temperature-based monopolar and bipolar radiofrequency, and liquid and gel chemoablation: laboratory studies and review of the literature. J Endour 18:83–104

    Article  Google Scholar 

  • Remzi M, Ozsoy M, Klingler HC, Susani M, Waldert M, Seitz C et al. (2006) Are small renal tumors harmless? Analysis of histopathological features according to tumors 4 cm or less in diameter. J Urol 176:896–899

    Article  PubMed  Google Scholar 

  • Rendon RA, Kachura JR, Sweet JM, Gertner MR, Sherar MD, Robinette M et al. (2002) The uncertainty of radio frequency treatment of renal cell carcinoma: findings at immediate and delayed nephrectomy. J Urol 167:1587–1592

    Article  PubMed  Google Scholar 

  • Shingleton WB, Sewell PE (2002a) Percutaneous cryoablation of renal cell carcinoma in a transplanted kidney. BJU Int 90:137–138

    Article  CAS  PubMed  Google Scholar 

  • Shingleton WB, Sewell PE Jr (2002b) Percutaneous renal cryoablation of renal tumors in patients with von HippelLindau disease. J Urol 167:1268–1270

    Article  PubMed  Google Scholar 

  • Shingleton WB, Sewell PE Jr (2003) Cryoablation of renal tumours in patients with solitary kidneys. BJU Int 92: 237–239

    Article  CAS  PubMed  Google Scholar 

  • Sisul DM, Liss MA, Palazzi KL, Briles K, Mehrazin R, Gold RE et al. (2013) RENAL nephrometry score is associated with complications after renal cryoablation: a multicenter analysis. Urology 81:775–780

    Article  PubMed  Google Scholar 

  • Strom KH, Derweesh I, Stroup SP, Malcolm JB, L'Esperance J, Wake RW et al. (2011) Second prize: recurrence rates after percutaneous and laparoscopic renal cryoablation of small renal masses: does the approach make a difference? J Endour 25:371–375

    Article  Google Scholar 

  • Tacke J, Mahnken A, Roggan A, Gunther RW (2004) Multipolar radiofrequency ablation: first clinical results. Rofo 176:324–329

    Article  CAS  PubMed  Google Scholar 

  • Tan BJ, El-Hakim A, Morgenstern N, Semerdzhiev Y, Smith A, Lee BR (2004) Comparison of laparoscopic saline infused to dry radio frequency ablation of renal tissue: evolution of histological infarct in the porcine model. J Urol 172:2007–2012

    Article  PubMed  Google Scholar 

  • Urena R, Mendez F, Woods M, Thomas R, Davis R (2004) Laparoscopic partial nephrectomy of solid renal masses without hilar clamping using a monopolar radio frequency device. J Urol 171:1054–1056

    Article  PubMed  Google Scholar 

  • Wagner AA, Solomon SB, Su LM (2005) Treatment of renal tumors with radiofrequency ablation. J Endour 19: 643-652; discussion 652–653

    Google Scholar 

  • Wah TM, Irving HC, Gregory W, Cartledge J, Joyce AD, Selby PJ (2014) Radiofrequency ablation (RFA) of renal cell carcinoma (RCC): experience in 200 tumours. BJU Int 113: 416–428

    Article  PubMed  Google Scholar 

  • Wu F, Wang ZB, Chen WZ, Bai J, Zhu H, Qiao TY (2003) Preliminary experience using high intensity focused ultrasound for the treatment of patients with advanced stage renal malignancy. J Urol 170:2237–2240

    Article  PubMed  Google Scholar 

  • Wyler SF, Sulser T, Ruszat R, Weltzien B, Forster TH, Provenzano M et al. (2007) Intermediate-term results of retroperitoneoscopy-assisted cryotherapy for small renal tumours using multiple ultrathin cryoprobes. Eur Urol 51:971–979

    Article  PubMed  Google Scholar 

  • Zelkovic PF, Resnick MI (2003) Renal radiofrequency ablation: clinical status 2003. Curr Opin Urol 13:199–202

    Article  PubMed  Google Scholar 

  • Zlotta AR, Wildschutz T, Raviv G, Peny MO, van Gansbeke D, Noel JC et al. (1997) Radiofrequency interstitial tumor ablation (RITA) is a possible new modality for treatment of renal cancer: ex vivo and in vivo experience. J Endour 11:251–258

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2016 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Friebe, B. et al. (2016). Alternative Verfahren beim Nierenzellkarzinom. In: Schostak, M., Blana, A. (eds) Alternative operative Therapien in der Uroonkologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-44420-7_2

Download citation

  • DOI: https://doi.org/10.1007/978-3-662-44420-7_2

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-44419-1

  • Online ISBN: 978-3-662-44420-7

  • eBook Packages: Medicine (German Language)

Publish with us

Policies and ethics