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Molecular Farming

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Biotechnological Approaches to Barley Improvement

Part of the book series: Biotechnology in Agriculture and Forestry ((AGRICULTURE,volume 69))

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Abstract

Molecular farming presents a sustainable, green technology for the production of high value proteins. Barley has a number of qualities that make it an excellent seed-based platform for the manufacturing of recombinant proteins. Extensive domestication and human dependency make its cultivation, processing and quality control a very manageable task. High level of self-pollination provides for efficient biological containment, and tissue-specific accumulation of recombinant proteins in grains offers a stable, endotoxin-free environment for valuable proteins. A number of proteins have been produced by molecular farming in barley, and over 40 recombinant human growth factors are already manufactured in barley for the life science and medical research market.

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Acknowledgements

Árni Brynjólfsson and Brynhildur Ingvarsdóttir are thanked for assisting with layout of table and figures.

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Authors and Affiliations

  1. ORF Genetics, Vikurhvarfi 3, 203, Kopavogur, Iceland

    Einar Mäntylä & Björn L. Örvar

  2. Faculty of Pharmaceutical Sciences, University of Iceland Hagi, Hofsvallagata 53, 107, Reykjavík, Iceland

    Einar Mäntylä

Authors
  1. Einar Mäntylä
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  2. Björn L. Örvar
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Correspondence to Einar Mäntylä .

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Editors and Affiliations

  1. Leibniz Institute of Plant Genetics and Crop Plant Research (IPK), Gatersleben, Germany

    Jochen Kumlehn

  2. Leibniz Institute of Plant Genetics and Crop Plant Research (IPK), Gatersleben, Germany

    Nils Stein

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Mäntylä, E., Örvar, B.L. (2014). Molecular Farming. In: Kumlehn, J., Stein, N. (eds) Biotechnological Approaches to Barley Improvement. Biotechnology in Agriculture and Forestry, vol 69. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-44406-1_13

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