Management of Acute Radiation Side Effects

  • Jong H. Chung
  • Anurag K. Agrawal
  • Patrick S. Swift
Chapter
Part of the Pediatric Oncology book series (PEDIATRICO)

Abstract

Potential complications from radiation therapy requiring supportive care measures include acute, subacute (also called early delayed), and chronic (late delayed) entities and are directly related to the site of radiation, subsequent dose, and volume of tissue exposed. Here we specifically concentrate on acute and, to a lesser extent, subacute issues. Data in children, especially of a prospective nature, are quite limited, and therefore we rely on extrapolation of data from adult studies which may or may not include pediatric patients. Studies on simple and widely utilized historical treatment strategies are often lacking; therefore, reference to clinical practice guidelines is made where possible. Radiation toxicity is examined in a site- and dose-dependent fashion with a discussion of supportive care evidence to date and recommendations on evidence-based treatment guidelines, where available.

Keywords

Morphine Anemia Dexamethasone Thrombocytopenia Lactobacillus 

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Copyright information

© Springer Berlin Heidelberg 2015

Authors and Affiliations

  • Jong H. Chung
    • 1
  • Anurag K. Agrawal
    • 2
  • Patrick S. Swift
    • 3
  1. 1.Division of Pediatric Hematology/OncologyUniversity of California-Davis Children’s HospitalSacramentoUSA
  2. 2.Department of Hematology/OncologyChildrens Hospital and Research Center OaklandOaklandUSA
  3. 3.Professor of Radiation OncologyStanford University School of Medicine, Stanford Cancer CenterStanfordUSA

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