Abstract
The legume family includes important grain, forage, and agroforestry species. One of the major constraints for cultivation of these legumes is obviously production loss by disease (Graham and Vance in Plant Physiol 131(3):872–877, 2003). Thus, Lotus japonicus is utilized not only as a symbiotic model but also as a research platform for studying serious diseases in legumes. However, most of our knowledge about the defense mechanism in L. japonicus comes from the study of legume–rhizobia symbiosis. In this section, we mainly focus on the regulation of defense responses in host symbiotic process, the pathogenic aspect of symbiotic microbial partners, and then illustrate the Lotus pathogens.
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References
Alippi A (2005) Bacterial diseases of Lotus spp. Lotus Newslett 35(1):17–18
Ausmees N, Kobayashi H, Deakin WJ, Marie C, Krishnan HB, Broughton WJ, Perret X (2004) Characterization of NopP, a type III secreted effector of Rhizobium sp. strain NGR234. J Bacteriol 186(14):4774–4780
Bartsev AV, Deakin WJ, Boukli NM, McAlvin CB, Stacey G, Malnoë P, Broughton WJ, Staehelin C (2004) NopL, an effector protein of Rhizobium sp. NGR234, thwarts activation of plant defense reactions. Plant Physiol 134(2):871–879
Chen WM, Laevens S, Lee TM, Coenye T, De Vos P, Mergeay M, Vandamme P (2001) Ralstonia taiwanensis sp. nov., isolated from root nodules of Mimosa species and sputum of a cystic fibrosis patient. Int J Syst Evol Microbiol 51(Pt 5):1729–1735
Christie PJ, Vogel JP (2000) Bacterial type IV secretion: conjugation systems adapted to deliver effector molecules to host cells. Trends Microbiol 8(8):354–360
Cullimore JV, Ranjeva R, Bono JJ (2001) Perception of lipo-chitooligosaccharidic Nod factors in legumes. Trends Plant Sci 6(1):24–30
Deakin WJ, Broughton WJ (2009) Symbiotic use of pathogenic strategies: rhizobial protein secretion systems. Nat Rev Microbiol 7(4):312–320
Deakin WJ, Marie C, Saad MM, Krishnan HB, Broughton WJ (2005) NopA is associated with cell surface appendages produced by the type III secretion system of Rhizobium sp. strain NGR234. Mol Plant Microbe Interact 18(5):499–507
Dodds PN, Rathjen JP (2010) Plant immunity: towards an integrated view of plant-pathogen interactions. Nat Rev Genet 11(8):539–548
Felix G, Duran JD, Volko S, Boller T (1999) Plants have a sensitive perception system for the most conserved domain of bacterial flagellin. Plant J 18(3):265–276
Gomez-Gomez L, Boller T (2000) FLS2: an LRR receptor-like kinase involved in the perception of the bacterial elicitor flagellin in Arabidopsis. Mol Cell 5(6):1003–1011
Graham PH, Vance CP (2003) Legumes: importance and constraints to greater use. Plant Physiol 131(3):872–877
Hayashi M, Saeki Y, Haga M, Harada K, Kouchi H, Umehara Y (2012) Rj (rj) genes involved in nitrogen-fixing root nodule formation in soybean. Breed Sci 61(5):544–553
Heidrich K, Blanvillain-Baufume S, Parker JE (2012) Molecular and spatial constraints on NB-LRR receptor signaling. Curr Opin Plant Biol 15(4):385–391
Hueck CJ (1998) Type III protein secretion systems in bacterial pathogens of animals and plants. Microbiol Mol Biol Rev 62(2):379–433
Jones JD, Dangl JL (2006) The plant immune system. Nature 444(7117):323–329
Kambara K, Ardissone S, Kobayashi H, Saad MM, Schumpp O, Broughton WJ, Deakin WJ (2009) Rhizobia utilize pathogen-like effector proteins during symbiosis. Mol Microbiol 71(1):92–106
Kouchi H, Imaizumi-Anraku H, Hayashi M, Hakoyama T, Nakagawa T, Umehara Y, Suganuma N, Kawaguchi M (2010) How many peas in a pod? Legume genes responsible for mutualistic symbioses underground. Plant Cell Physiol 51(9):1381–1397
Krause A, Doerfel A, Göttfert M (2002) Mutational and transcriptional analysis of the type III secretion system of Bradyrhizobium japonicum. Mol Plant Microbe Interact 15(12):1228–1235
Lopez-Gomez M, Sandal N, Stougaard J, Boller T (2012) Interplay of flg22-induced defence responses and nodulation in Lotus japonicus. J Exp Bot 63(1):393–401
Marie C, Deakin WJ, Viprey V, Kopciñska J, Golinowski W, Krishnan HB, Perret X, Broughton WJ (2003) Characterization of Nops, nodulation outer proteins, secreted via the type III secretion system of NGR234. Mol Plant Microbe Interact 16(9):743–751
Miya A, Albert P, Shinya T, Desaki Y, Ichimura K, Shirasu K, Narusaka Y, Kawakami N, Kaku H, Shibuya N (2007) CERK1, a LysM receptor kinase, is essential for chitin elicitor signaling in Arabidopsis. Proc Natl Acad Sci U S A 104(49):19613–19618
Monaghan J, Zipfel C (2012) Plant pattern recognition receptor complexes at the plasma membrane. Curr Opin Plant Biol 15(4):349–357
Moulin L, Munive A, Dreyfus B, Boivin-Masson C (2001) Nodulation of legumes by members of the beta-subclass of Proteobacteria. Nature 411(6840):948–950
Nakagawa T, Kaku H, Shimoda Y, Sugiyama A, Shimamura M, Takanashi K, Yazaki K, Aoki T, Shibuya N, Kouchi H (2011) From defense to symbiosis: limited alterations in the kinase domain of LysM receptor-like kinases are crucial for evolution of legume-Rhizobium symbiosis. Plant J 65(2):169–180
Okazaki S, Okabe S, Higashi M, Shimoda Y, Sato S, Tabata S, Hashiguchi M, Akashi R, Gottfert M, Saeki K (2010) Identification and functional analysis of type III effector proteins in Mesorhizobium loti. Mol Plant Microbe Interact 23(2):223–234
Perret X, Freiberg C, Rosenthal A, Broughton WJ, Fellay R (1999) High-resolution transcriptional analysis of the symbiotic plasmid of Rhizobium sp. NGR234. Mol Microbiol 32(2):415–425
Radutoiu S, Madsen LH, Madsen EB, Felle HH, Umehara Y, Gronlund M, Sato S, Nakamura Y, Tabata S, Sandal N, Stougaard J (2003) Plant recognition of symbiotic bacteria requires two LysM receptor-like kinases. Nature 425(6958):585–592
Saad MM, Kobayashi H, Marie C, Brown IR, Mansfield JW, Broughton WJ, Deakin WJ (2005) NopB, a type III secreted protein of Rhizobium sp. strain NGR234, is associated with pilus-like surface appendages. J Bacteriol 187(3):1173–1181
Sánchez C, Iannino F, Deakin WJ, Ugalde RA, Lepek VC (2009) Characterization of the Mesorhizobium loti MAFF303099 type-three protein secretion system. Mol Plant Microbe Interact 22(5):519–528
Schauser L, Roussis A, Stiller J, Stougaard J (1999) A plant regulator controlling development of symbiotic root nodules. Nature 402(6758):191–195
Schumpp O, Ramel ME, Gugerli P, Broughton WJ, Deakin WJ (2007) Identification of a Lotus viral pathogen. J Plant Res 120(5):651–654
Segonzac C, Zipfel C (2011) Activation of plant pattern-recognition receptors by bacteria. Curr Opin Microbiol 14(1):54–61
Shao F, Golstein C, Ade J, Stoutemyer M, Dixon JE, Innes RW (2003) Cleavage of Arabidopsis PBS1 by a bacterial type III effector. Sci Signal 301(5637):1230
Shimada N, Sato S, Akashi T, Nakamura Y, Tabata S, Ayabe S, Aoki T (2007) Genome-wide analyses of the structural gene families involved in the legume-specific 5-deoxyisoflavonoid biosynthesis of Lotus japonicus. DNA Res 14(1):25–36
Shimizu T, Nakano T, Takamizawa D, Desaki Y, Ishii-Minami N, Nishizawa Y, Minami E, Okada K, Yamane H, Kaku H, Shibuya N (2010) Two LysM receptor molecules, CEBiP and OsCERK1, cooperatively regulate chitin elicitor signaling in rice. Plant J 64(2):204–214
Sisterna M, Lori GA (2005) Fungal diseases on Lotus spp in Argentina. Lotus Newslett 35(1):15–16
Skorpil P, Saad MM, Boukli NM, Kobayashi H, Ares-Orpel F, Broughton WJ, Deakin WJ (2005) NopP, a phosphorylated effector of Rhizobium sp. strain NGR234, is a major determinant of nodulation of the tropical legumes Flemingia congesta and Tephrosia vogelii. Mol Microbiol 57(5):1304–1317
Spaink HP (1995) The molecular basis of infection and nodulation by rhizobia: the ins and outs of sympathogenesis. Annu Rev Phytopathol 33(1):345–368
Takeuchi K, Tomioka K, Kouchi H, Nakagawa T, Kaku H (2007) A novel pathosystem to study the interactions between Lotus japonicus and Fusarium solani. J Gen Plant Pathol 73:336–341
Tsukui T, Eda S, Kaneko T, Sato S, Okazaki S, Kakizaki-Chiba K, Itakura M, Mitsui H, Yamashita A, Terasawa K (2013) The Type III Secretion System of Bradyrhizobium japonicum USDA122 mediates symbiotic incompatibility with Rj2 soybean plants. Appl Environ Microbiol 79(3):1048–1051
Vandamme P, Goris J, Chen WM, de Vos P, Willems A (2002) Burkholderia tuberum sp. nov. and Burkholderia phymatum sp. nov., nodulate the roots of tropical legumes. Syst Appl Microbiol 25(4):507–512
Velazquez E, Peix A, Zurdo-Pineiro JL, Palomo JL, Mateos PF, Rivas R, Munoz-Adelantado E, Toro N, Garcia-Benavides P, Martinez-Molina E (2005) The coexistence of symbiosis and pathogenicity-determining genes in Rhizobium rhizogenes strains enables them to induce nodules and tumors or hairy roots in plants. Mol Plant Microbe Interact 18(12):1325–1332
Viboud GI, Bliska JB (2005) Yersinia outer proteins: role in modulation of host cell signaling responses and pathogenesis. Annu Rev Microbiol 59:69–89
Viprey V, Del Greco A, Golinowski W, Broughton WJ, Perret X (1998) Symbiotic implications of type III protein secretion machinery in Rhizobium. Mol Microbiol 28(6):1381–1389
Yang S, Tang F, Gao M, Krishnan HB, Zhu H (2010) R gene-controlled host specificity in the legume-rhizobia symbiosis. Proc Natl Acad Sci USA 107(43):18735–18740
Zehner S, Schober G, Wenzel M, Lang K, Göttfert M (2008) Expression of the Bradyrhizobium japonicum type III secretion system in legume nodules and analysis of the associated tts box promoter. Mol Plant Microbe Interact 21(8):1087–1093
Zhang XC, Wu X, Findley S, Wan J, Libault M, Nguyen HT, Cannon SB, Stacey G (2007) Molecular evolution of lysin motif-type receptor-like kinases in plants. Plant Physiol 144(2):623–636
Zhu H, Riely BK, Burns NJ, Ane JM (2006) Tracing nonlegume orthologs of legume genes required for nodulation and arbuscular mycorrhizal symbioses. Genetics 172(4):2491–2499
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Nakagawa, T., Okazaki, S., Shibuya, N. (2014). Genes Involved in Pathogenesis and Defense Responses. In: Tabata, S., Stougaard, J. (eds) The Lotus japonicus Genome. Compendium of Plant Genomes. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-44270-8_15
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DOI: https://doi.org/10.1007/978-3-662-44270-8_15
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