Functional Microanatomical Model of Meissner Corpuscle
A multi-scale framework of human tactile sensation has been developed. The framework consists of two mechanical stages and a post-processing stage. In the first stage, a fingerpad and a stimulus are modelled. The second stage contains a slab of skin containing a Meissner corpuscle. The mechanical output of the second stage is processed by a mechanosensory channel activation model and a spike generator. To our knowledge, this is the first framework linking different levels of sensory processing from mechano-transduction to spike-train comparison. The results of the model are compared to the microneurographical data of a RA1 mechanosensory afferent fibre. The framework could be used as a tool for studying the finger pad-surface interaction in scientific and industrial communities related to touch.
KeywordsMeissner corpuscle Multi-scale FEM Touch Tactile sensibility Cutaneous mechanoreceptors Mechano-transduction
This work was supported by the European Union under the FP7 programs FP7-NMP-228844 NanoBioTouch and FP7-PEOPLE-317100 Prototouch. The FEM models were prepared in cooperation with Rockfield Software Ltd. and C3M d.o.o. Experimental results were kindly provided by prof. Johan Wessberg from Department of Physiology, University of Gothenburg, Sweden.
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