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Video Capsule Endoscopy in Children

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Video Capsule Endoscopy

Abstract

Almost all but the most proximal and distal segments of the small bowel are essentially out of range of standard endoscopes. Push enteroscopy generally allows visualization only of the proximal areas of the jejunum, up to about 150 cm distal to the pylorus. Moreover, the need for an overtube (15 mm) limits the applicability of this relatively invasive technique in children [1]. Intraoperative enteroscopy necessitates more invasive abdominal laparotomy or laparoscopy, with potential complications such as prolonged postoperative ileus, obstruction, perforation, and fistula formation [2]. Balloon-assisted enteroscopy is a novel method that has shown promising initial results for achieving complete enteroscopy and providing therapy without requiring laparotomy [3]. This technique generally entails a long period of manipulation, however, so general anesthesia is often needed. Moreover, its availability is limited, with little experience in pediatric patients reported to date [4]. Thus, the small bowel has been deemed the last unexplored frontier in terms of pediatric endoscopy [5].

The work was first published in 2006 by Springer Medizin Verlag Heidelberg with the following title: Atlas of Video Capsule Endoscopy.

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References

  1. MacKenzie JF. Push enteroscopy. Gastrointest Endosc Clin N Am. 1999;9:29–36.

    CAS  PubMed  Google Scholar 

  2. Waye JD. Small-bowel endoscopy. Endoscopy. 2003;35:15–21.

    Article  CAS  PubMed  Google Scholar 

  3. Yamamoto H, Kita H, Sunada K, et al. Clinical outcomes of double-balloon endoscopy for the diagnosis and treatment of small-intestinal diseases. Clin Gastroenterol Hepatol. 2004;2:1010–6.

    Article  PubMed  Google Scholar 

  4. Thomson M, Venkatesh K, Elmalik K, et al. Double balloon enteroscopy in children: diagnosis, treatment, and safety. World J Gastroenterol. 2010;16:56–62.

    Article  PubMed Central  PubMed  Google Scholar 

  5. Seidman EG, Sant’Anna AMGA, Dirks MH. Potential applications of wireless capsule endoscopy in the pediatric age group. Gastrointest Endosc Clin N Am. 2004;14:207–18.

    Article  PubMed  Google Scholar 

  6. Iddan G, Meron G, Glukhovsky A, Swain P. Wireless capsule endoscopy. Nature. 2000;405:417.

    Article  CAS  PubMed  Google Scholar 

  7. Costamagna G, Shah SK, Riccioni ME, et al. A prospective trial comparing small bowel radiographs and video capsule endoscopy for suspected small bowel disease. Gastroenterology. 2002;123:999–1005.

    Article  PubMed  Google Scholar 

  8. Ell C, Remke S, May A, et al. The first prospective controlled trial comparing wireless capsule endoscopy in chronic gastrointestinal bleeding. Endoscopy. 2002;34:685–9.

    Article  CAS  PubMed  Google Scholar 

  9. Pennazio M, Santucci R, Rondonotti E, et al. Outcome of patients with obscure gastrointestinal bleeding after capsule endoscopy: report of 100 consecutive cases. Gastroenterology. 2004;126:643–53.

    Article  PubMed  Google Scholar 

  10. Triester SL, Leighton JA, Gurudu SR, et al. A meta-analysis of capsule endoscopy (CE) compared to other modalities in patients with non-stricturing small bowel Crohn disease (NSCD). Am J Gastroenterol. 2004;99:S271–2.

    Article  Google Scholar 

  11. Petroniene R, Dubenco E, Baker JP, et al. Given capsule endoscopy in celiac disease: evaluation of diagnostic accuracy and interobserver variation. Am J Gastroenterol. 2005;100:685–94.

    Article  PubMed  Google Scholar 

  12. de Mascarenhas-Saraiva MN, da Silva Araujo Lopes LM. Small-bowel tumors diagnosed by wireless capsule endoscopy: report of five cases. Endoscopy. 2003;35:865–8.

    Article  PubMed  Google Scholar 

  13. Sant’Anna AMGA, Dubois J, Miron MJ, Seidman EG. Wireless capsule endoscopy for obscure small bowel disorders: final results of the first pediatric controlled trial. Clin Gastroenterol Hepatol. 2005;3:264–70.

    Article  Google Scholar 

  14. Urbain D, Tresinie M, De Looz D, et al. Capsule endoscopy in paediatrics: multicentric Belgian study. Acta Gastroenterol Belg. 2007;70:11–4.

    PubMed  Google Scholar 

  15. de Angelis GL, Fornaroli F, de Angelis N, et al. Wireless capsule endoscopy for pediatric small-bowel diseases. Am J Gastroenterol. 2007;102:1749–57.

    Article  Google Scholar 

  16. Cohen SA, Ephrath H, Lewis JD, et al. Pediatric capsule endoscopy: review of the small bowel and patency capsules. J Pediatr Gastroenterol Nutr. 2012;54:409–13.

    Article  PubMed  Google Scholar 

  17. Cohen SA, Klevens AI. Use of capsule endoscopy in diagnosis and management of pediatric patients, based on meta-analysis. Clin Gastroenterol Hepatol. 2011;9:490–6.

    Article  PubMed  Google Scholar 

  18. Sant’Anna AMGA, Seidman EG. Wireless capsule endoscopy: comparison study in pediatric and adult patients. J Pediatr Gastroenterol Nutr. 2003;37:332.

    Article  Google Scholar 

  19. Arguelles-Arias F, Caunedo A, Romero J, et al. The value of capsule endoscopy in pediatric patients with a suspicion of Crohn’s disease. Endoscopy. 2004;36:869–73.

    Article  CAS  PubMed  Google Scholar 

  20. Cohen SA, Gralnek IM, Ephrath H, et al. The use of patency capsule in pediatric Crohn’s disease: a prospective evaluation. Dig Dis Sci. 2011;56:860–5.

    Article  PubMed  Google Scholar 

  21. Cohen SA, Gralnek IM, Ephrath H, et al. Capsule endoscopy may reclassify pediatric inflammatory bowel disease: a historical analysis. J Pediatr Gastroenterol Nutr. 2008;47:31–6.

    Article  PubMed  Google Scholar 

  22. Gralnek IM, Cohen SA, Ephrath H, et al. Small bowel capsule endoscopy impacts diagnosis and management of pediatric inflammatory bowel disease: a prospective study. Dig Dis Sci. 2012;57:465–71.

    Article  PubMed  Google Scholar 

  23. Barkay O, Moshkowitz M, Reif S. Crohn’s disease diagnosed by wireless capsule endoscopy in adolescents with abdominal pain, protein-losing enteropathy, anemia and negative endoscopic and radiologic findings. Isr Med Assoc J. 2005;7:262–3.

    Google Scholar 

  24. Maiden L, Thjodleifsson B, Theodors A, et al. A quantitative analysis of NSAID-induced small bowel pathology by capsule enteroscopy. Gastroenterology. 2005;128:1172–8.

    Article  PubMed  Google Scholar 

  25. Goldstein JL, Eisen GM, Lewis B, et al. Video capsule endoscopy to prospectively assess small bowel injury with celecoxib, naproxen plus omeprazole, and placebo. Clin Gastroenterol Hepatol. 2005;3:133–41.

    Article  PubMed  Google Scholar 

  26. Mata A, Bordas JM, Feu F, et al. Wireless capsule endoscopy in patients with obscure gastrointestinal bleeding: a comparative study with push enteroscopy. Aliment Pharmacol Ther. 2004;​20:189–94.

    Article  CAS  PubMed  Google Scholar 

  27. Soares J, Lopes L, Vilas Boas G, Pinho C. Wireless capsule endoscopy for evaluation of phenotypic expression of small-bowel polyps in patients with Peutz-Jeghers syndrome and in symptomatic first-degree relatives. Endoscopy. 2004;36:1060–6.

    Article  CAS  PubMed  Google Scholar 

  28. Caspari R, von Falkenhausen M, Krautmacher C, et al. Comparison of capsule endoscopy and magnetic resonance imaging for the detection of polyps of the small intestine in patients with familial adenomatous polyposis or with Peutz-Jeghers’ syndrome. Endoscopy. 2004;36:1054–9.

    Article  CAS  PubMed  Google Scholar 

  29. Schulmann K, Hollerbach S, Kraus K, et al. Feasibility and diagnostic utility of video capsule endoscopy for the detection of small bowel polyps in patients with hereditary polyposis syndromes. Am J Gastroenterol. 2005;100:27–37.

    Article  PubMed  Google Scholar 

  30. Iaquinto G, Fornasarig M, Quaia M, et al. Capsule endoscopy is useful and safe for small-bowel surveillance in familial adenomatous polyposis. Gastrointest Endosc. 2008;67:61–7.

    Article  PubMed  Google Scholar 

  31. Postgate A, Hyer W, Phillips R, et al. Feasibility of video capsule endoscopy in the management of children with Peutz-Jeghers syndrome: a blinded comparison with barium enterography for the detection of small bowel polyps. J Pediatr Gastroenterol Nutr. 2009;49:417–23.

    Article  PubMed  Google Scholar 

  32. Pennazio M. Enteroscopy in the diagnosis and management of obscure gastrointestinal bleeding. Gastrointest Endosc Clin N Am. 2009;19:409–26.

    Article  PubMed  Google Scholar 

  33. Rondonotti E, Marmo R, Petracchini M, et al. The American Society for Gastrointestinal Endoscopy (ASGE) diagnostic algorithm for obscure gastrointestinal bleeding: eight burning questions from everyday clinical practice. Dig Liver Dis. 2013;45:179–85.

    Article  PubMed  Google Scholar 

  34. Lai LH, Wong GLH, Chow DKL, et al. Long-term follow-up of patients with obscure gastrointestinal bleeding after negative capsule endoscopy. Am J Gastroenterol. 2006;101:1224–8.

    Article  PubMed  Google Scholar 

  35. Lecleire S, Iwanicki-Caron I, Di-Fiore A, et al. Yield and impact of emergency capsule enteroscopy in severe obscure-overt gastrointestinal bleeding. Endoscopy. 2012;44:337–42.

    Article  CAS  PubMed  Google Scholar 

  36. De Bona M, Bellumat A, De Boni M. Capsule endoscopy for the diagnosis and follow-up of blue rubber bleb nevus syndrome. Dig Liver Dis. 2005;37:451–3.

    Article  PubMed  Google Scholar 

  37. Murray JA, Brogan D, Van dyke C, et al. Mapping the extent of untreated celiac disease with capsule enteroscopy. Gastrointest Endosc. 2004;59:AB101.

    Article  Google Scholar 

  38. Collin P, Rondonotti E, Lundin K, et al. Video capsule endoscopy in celiac disease: current clinical practice. J Dig Dis. 2012;13:94–9.

    Article  PubMed  Google Scholar 

  39. Cellier C, Green PH, Collin P, Murray J. ICCE consensus for celiac disease. Endoscopy. 2005;37:1055–9.

    Article  CAS  PubMed  Google Scholar 

  40. Peretti N, Sant’Anna AMGA, Dirks MH, Seidman EG. Capsule endoscopy detects lymphangiectasia missed by other means. 4th International conference on capsule endoscopy, Miami, 2005 Mar 7–8, p. 189.

    Google Scholar 

  41. Mihaly F, Nemeth A, Zagoni T, et al. Gastrointestinal manifestations of common variable immunodeficiency diagnosed by video- and capsule endoscopy. Endoscopy. 2005;37:603–4.

    Article  CAS  PubMed  Google Scholar 

  42. Yakoub-Agha I, Maunoury V, Wacrenier A, et al. Impact of small bowel exploration using video-capsule endoscopy in the management of acute gastrointestinal graft-versus-host disease. Transplantation. 2004;78:1697–701.

    Article  PubMed  Google Scholar 

  43. Shamir R, Hino B, Hartman C, et al. Wireless video capsule in pediatric patients with functional abdominal pain. J Pediatr Gastroenterol Nutr. 2007;44:45–50.

    Article  CAS  PubMed  Google Scholar 

  44. Barth BA, Donovan K, Fox VL. Endoscopic placement of the capsule endoscope in children. Gastrointest Endosc. 2004;60:818–21.

    Article  PubMed  Google Scholar 

  45. Bass LM, Misiewicz L. Use of a real-time viewer for endoscopic deployment of capsule endoscope in the pediatric population. J Pediatr Gastroenterol Nutr. 2012;55:552–5.

    Article  PubMed  Google Scholar 

  46. Fritscher-Ravens A, Scherbakov P, Bufler P, et al. The feasibility of wireless capsule endoscopy in detecting small intestinal pathology in children under the age of 8 years: a multicentre European study. Gut. 2009;58:1467–72.

    Article  CAS  PubMed  Google Scholar 

  47. Atay O, Mahajan L, Kay M, et al. Risk of capsule endoscope retention in pediatric patients: a large single-center experience and review of the literature. J Pediatr Gastroenterol Nutr. 2009;49:196–201.

    Article  PubMed  Google Scholar 

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Correspondence to Ernest G. Seidman .

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© 2014 Springer-Verlag Berlin Heidelberg

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Seidman, E.G., de’ Angelis, G.L., Sant’Anna, A., Dirks, M.H., Thomson, M. (2014). Video Capsule Endoscopy in Children. In: Keuchel, M., Hagenmüller, F., Tajiri, H. (eds) Video Capsule Endoscopy. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-44062-9_38

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  • DOI: https://doi.org/10.1007/978-3-662-44062-9_38

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