Involvement of the Small Intestine in Systemic Diseases

  • Adriana Safatle-Ribeiro
  • Gérard Gay
  • Eberhard Barth
  • Martin Keuchel


Systemic diseases are rare and etiologically diverse. They can affect a variety of organs; involvement of the small bowel occurs with varying degrees of frequency [1]. The assignment of symptoms and findings (including endoscopic findings) to specific disease entities can be a formidable challenge. A diagnosis cannot be made from endoscopic findings alone.


Amyloidosis Sarcoidosis Vasculitis IgA vasculitis Henoch-Schönlein Polyarteritis nodosa Behçet’s syndrome Takayasu’s arteritis Collagen diseases Common variable immunodeficiency syndrome Hemosiderosis Abetalipoproteinemia Sea-blue histiocytosis Noonan syndrome Goldenhar syndrome 


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  1. Amyloidosis Foundation
  2. The European League Against Rheumatism
  3. Lupus Foundation of America
  4. American College of Rheumatology

Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  • Adriana Safatle-Ribeiro
    • 1
  • Gérard Gay
    • 2
  • Eberhard Barth
    • 3
  • Martin Keuchel
    • 4
  1. 1.Department of GastroenterologyUniversity of Sao PauloSao PauloBrazil
  2. 2.Department of Gastroenterology and HepatologyUniversity Hospital of Strasbourg, Nouvel Hôpital CivilStrasbourgFrance
  3. 3.Gastroenterology and Rheumatology PracticeHamburgGermany
  4. 4.Department of Internal MedicineBethesda Krankenhaus BergedorfHamburgGermany

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