Abstract
Systemic diseases are rare and etiologically diverse. They can affect a variety of organs; involvement of the small bowel occurs with varying degrees of frequency [1]. The assignment of symptoms and findings (including endoscopic findings) to specific disease entities can be a formidable challenge. A diagnosis cannot be made from endoscopic findings alone.
The work was first published in 2006 by Springer Medizin Verlag Heidelberg with the following title: Atlas of Video Capsule Endoscopy.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Hagenmüller F. Funktionelle und morphologische Veränderungen des Dünndarms bei systemischen und extraintestinalen Erkrankungen. In: Caspary W, editor. Handbuch der Inneren Medizin. Bd III/3B: Dünndarm. Berlin: Springer; 1983. p. 611–30.
Sattianayagam PT, Hawkins PN, Gillmore JD. Systemic amyloidosis and the gastrointestinal tract. Nat Rev Gastroenterol Hepatol. 2009;10:608–17.
Ebert EC, Nagar M. Gastrointestinal manifestations of amyloidosis. Am J Gastroenterol. 2008;103:776–87.
Linke R, Altland K, Ernst J, et al. Praktische Hinweise zur Diagnose und Therapie generalisierter Amyloidosen. Dtsch Ärzteblatt. 1998;95:A2626–36.
Saeger W, Röcken C. Amyloid: microscopic demonstration, classification and clinical correlation. [Article in German]. Pathologe. 1998;19:345–54.
Peny MO, Debongnie JC, Haot J, van Gossum A. Localized amyloid tumor in small bowel. Dig Dis Sci. 2000;45:1850–3.
Barzola S, Lespi P, Fuentes R. Intestinal bleeding associated with systemic amyloidosis. [Article in Spanish]. Acta Gastroenterol Latinoam. 1998;28:257–9.
Stelzner M, Krug B. Gastrointestinal amyloidosis: differential diagnosis and indications for surgical therapy. Chirurg. 1991;62:493–9.
Koppelman RN, Stollman NH, Baigorri F, Rogers AI. Acute small bowel pseudoobstruction due to AL amyloidosis: a case report and literature review. Am J Gastroenterol. 2000;95:294–6.
Hayman SR, Lacy MQ, Kyle RA, Gertz MA. Primary systemic amyloidosis: a cause of malabsorption syndrome. Am J Med. 2001;111:535–40.
Hokama A, Kishimoto K, Nakamoto M, et al. Endoscopic and histopathological features of gastrointestinal amyloidosis. World J Gastrointest Endosc. 2011;3:157–61.
Yoshii S, Mabe K, Nosho K, et al. Submucosal hematoma is a highly suggestive finding for amyloid light-chain amyloidosis: two case reports. World J Gastrointest Endosc. 2012;4:434–7.
Cowan AJ, Skinner M, Seldin DC, et al. Amyloidosis of the gastrointestinal tract: a 13-year, single-center, referral experience. Haematologica. 2013;98:141–6.
Vahid B, Spodik M, Braun KN, et al. Sarcoidosis of gastrointestinal tract: a rare disease. Dig Dis Sci. 2007;52:3316–20.
Marie I, Sauvetre G, Levesque H. Small intestinal involvement revealing sarcoidosis. QJM. 2010;103:60–2.
Tsibouris P, Kalantzis C, Alexandrakis G, et al. Capsule endoscopy findings in a case of intestinal sarcoidosis. Endoscopy. 2009;41 Suppl 2:E191.
Culver DA. Sarcoidosis. Immunol Allergy Clin North Am. 2012;32:487–511.
Costabel U. Sarkoidose. In: Paumgartner G, Steinbeck G, editors. Therapie innerer Krankheiten, 10. Berlin: Springer; 2003. p. 414–9.
Jennette JC, Falk RJ, Andrassy K, et al. Nomenclature of systemic vasculitides. Proposal of an international consensus conference. Arthritis Rheum. 1994;37:187–92.
Jennette JC, Falk RJ, Bacon PA, et al. 2012 revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides. Arthritis Rheum. 2013;65:1–11.
Ha HK, Lee SH, Rha SE, et al. Radiologic features of vasculitis involving the gastrointestinal tract. Radiographics. 2000;3:779–94.
Ahn E, Luk A, Chetty R, Butany J. Vasculitides of the gastrointestinal tract. Semin Diagn Pathol. 2009;2:77–88.
Esaki M, Matsumoto T, Nakamura S, et al. GI involvement in Henoch-Schönlein purpura. Gastrointest Endosc. 2002;56:920–3.
Szer IS. Gastrointestinal and renal involvement in vasculitis: management strategies in Henoch-Schönlein purpura. Cleve Clin J Med. 1999;66:312–7.
Skogestad E. Capsule endoscopy in Henoch-Schonlein purpura. Endoscopy. 2005;37:189.
Keuchel M, Baltes P, Stövesand-Ruge B, et al. Henoch Schönlein Purpura. VJGIEN. 2013;1:235–6.
Ozen S, Pistorio A, Iusan SM, et al. EULAR/PRINTO/PRES criteria for Henoch-Schonlein purpura, childhood polyarteritis nodosa, childhood Wegener granulomatosis and childhood Takayasu arteritis: Ankara 2008. Part II: final classification criteria. Ann Rheum Dis. 2010;69:798–806.
Churg J, Strauss L. Allergic granulomatosis, allergic angiitis, and periarteritis nodosa. Am J Pathol. 1951;27:277–301.
Nakamura Y, Sakurai Y, Matsubara T, et al. Multiple perforated ulcers of the small intestine associated with allergic granulomatous angiitis: report of a case. Surg Today. 2002;32:541–6.
Suzuki T, Matsushima M, Arase Y, et al. Double-balloon endoscopy-diagnosed multiple small intestinal ulcers in a Churg-Strauss syndrome patient. World J Gastrointest Endosc. 2012;4:194–6.
Ushiki A, Koizumi T, Kubo K, et al. Colonic sarcoidosis presenting multiple submucosal tumor-like lesions. Intern Med. 2009;48:1813–6.
Murakami S, Misumi M, Sakata H, et al. Churg-Strauss syndrome manifesting as perforation of the small intestine: report of a case. Surg Today. 2004;34:788–92.
Barnes CG. Behcet’s syndrome – classification criteria. Ann Med Interne (Paris). 1999;150:477–82.
Korman U, Cantasdemir M, Kurugoglu S, et al. Enteroclysis findings of intestinal Behçet disease: a comparative study with Crohn’s disease. Abdom Imaging. 2003;28:308–12.
Pretorius ES, Hruban RH, Fishman EK. Inflammatory pseudotumor of the terminal ileum mimicking malignancy in a patient with Behçet’s disease. CT and pathological findings. Clin Imaging. 1996;20:191–3.
Neves FS, Fylyk SN, Lage LV, et al. Behçet’s disease: clinical value of the video capsule endoscopy for small intestine examination. Rheumatol Int. 2009;5:601–3.
Wu QJ, Zhang FC, Zhang X. Adamantiades-Behcet’s disease-complicated gastroenteropathy. World J Gastroenterol. 2012;18:609–15.
Hokama A, Kishimoto K, Ihama Y, et al. Endoscopic and radiographic features of gastrointestinal involvement in vasculitis. World J Gastrointest Endosc. 2012;4:50–6.
Carson CW, Conn DL, Czaja AJ, et al. Frequency and significance of antibodies to hepatitis C virus in polyarteritis nodosa. J Rheumatol. 1993;20:304–9.
Lidar M, Lipschitz N, Langevitz P, Shoenfeld Y. The infectious etiology of vasculitis. Autoimmunity. 2009;42:432–8.
Guillevin L. Infections in vasculitis. Best practice & research. Clin Rheumatol. 2013;27:19–31.
Becker A, Mader R, Elias M, et al. Duodenal necrosis as the presenting manifestation of polyarteritis nodosa. Clin Rheumatol. 2002;21:314–6.
Ueda C, Hirohata Y, Kihara Y, et al. Pancreatic cancer complicated by disseminated intravascular coagulation associated with production of tissue factor. J Gastroenterol. 2001;36:848–50.
Villiger PM, Guillevin L. Microscopic polyangiitis: clinical presentation. Autoimmun Rev. 2010;9:812–9.
Chung SA, Seo P. Microscopic polyangiitis. Rheum Dis Clin North Am. 2010;36:545–58.
Storesund B, Gran JT, Koldingsnes W. Severe intestinal involvement in Wegener’s granulomatosis: report of two cases and review of the literature. Br J Rheumatol. 1998;37:387–90.
Deniz K, Ozşeker HS, Balas S, et al. Intestinal involvement in Wegener’s granulomatosis. J Gastrointestin Liver Dis. 2007;16:329–31.
Simon S, Schittko G, Bösenberg H, et al. Fulminant course of a Takayasu’s arteritis and rare mesenteric arterial manifestation. [Article in German]. Z Rheumatol. 2006;65(520):522–6.
Sasamura H, Nakamoto H, Ryuzaki M, et al. Repeated intestinal ulcerations in a patient with systemic lupus erythematosus and high serum antiphospholipid antibody levels. South Med J. 1991;84:515–7.
Moriuchi J, Ichikawa Y, Takaya M, et al. Lupus cystitis and perforation of the small bowel in a patient with systemic lupus erythematosus and overlapping syndrome. Clin Exp Rheumatol. 1989;7:533–6.
Nguyen H, Khanna N. Intestinal pseudo-obstruction as a presenting manifestation of systemic lupus erythematosus: case report and review of the literature. South Med J. 2004;97:186–9.
Marie I, Levesque H, Ducrotte P, Courtois H. Involvement of the small intestine in systemic scleroderma. Rev Med Interne. 1999;20:504–13.
Ebert EC, Ruggiero FM, Seibold JR. Intestinal perforation. A common complication of scleroderma. Dig Dis Sci. 1997;42:549–53.
Harrison E, Herrick AL, McLaughlin JT, Lal S. Malnutrition in systemic sclerosis. Rheumatology (Oxford). 2012;51:1747–56.
Savarino E, Mei F, Parodi A, et al. Gastrointestinal motility disorder assessment in systemic sclerosis. Rheumatology (Oxford). 2013;52:1095–100.
Díez R, García MJ, Vivas S, et al. Gastrointestinal manifestations in patients with primary immunodeficiencies causing antibody deficiency. Gastroenterol Hepatol. 2010;5:347–51.
Malamut G, Verkarre V, Suarez F, et al. The enteropathy associated with common variable immunodeficiency: the delineated frontiers with celiac disease. Am J Gastroenterol. 2010;10:2262–75.
Mihaly E, Nemeth A, Zagoni T, et al. Gastrointestinal manifestations of common variable immunodeficiency diagnosed by video- and capsule endoscopy. Endoscopy. 2005;37:603–4.
Biagi F, Bianchi PI, Zilli A, et al. The significance of duodenal mucosal atrophy in patients with common variable immunodeficiency: a clinical and histopathologic study. Am J Clin Pathol. 2012;2:185–9.
Washington K, Stenzel TT, Buckley RH, Gottfried MR. Gastrointestinal pathology in patients with common variable immunodeficiency and X-linked agammaglobulinemia. Am J Surg Pathol. 1996;20:1240–52.
Kwong W, Kalmaz D. Jejunal hemosiderosis detected with small bowel capsule endoscopy. VHJOE. 2013;12(1). http://www.vhjoe.org/index.php/vhjoe/article/viewFile/86/139
Sharp D, Blinderman L, Combs KA, et al. Cloning and gene defects in microsomal triglyceride transfer protein associated with abetalipoproteinaemia. Nature. 1993;365:65–9.
Gay G, Fassler I, Florent C, Delvaux M. Malabsorption. In: Halpern M, Jacob H, editors. Atlas of capsule endoscopy. Norcross: Given Imaging; 2002. p. 83–101.
Gay G, Delmotte JS. Abeta and hypobetalipoproteinemias. In: Rossini F, Gay G, editors. Atlas of enteroscopy. Berlin: Springer; 1998. p. 119–20.
Candoni A, Grimaz S, Doretto P, et al. Sea-blue histiocytosis secondary to Niemann-Pick disease type B: a case report. Ann Hematol. 2001;10:620–2.
Suzuki O, Abe M. Secondary sea-blue histiocytosis derived from Niemann-Pick disease. J Clin Exp Hematop. 2007;47:19–21.
Safatle-Ribeiro AV, Baba ER, Iriya K. Double-balloon endoscopy reveals sea-blue histiocytosis affecting the small bowel (with video). Gastrointest Endosc. 2010;6:1266; discussion 1266–7.
Tartaglia M, Gelb BD, Zenker M. Noonan syndrome and clinically related disorders. Best Pract Res Clin Endocrinol Metab. 2011;25:161–79.
Yoshino H, Okumachi Y, Akisaki T, et al. Bleeding from the small intestine and aortic regurgitation in Noonan syndrome. Intern Med. 2011;50:2611–3.
Sgouros SN, Karamanolis G, Papadopoulou E, et al. Postbiopsy intramural hematoma of the duodenum in an adult with Noonan’s syndrome. J Gastroenterol Hepatol. 2004;10:1217–9.
Touliatou V, Fryssira H, Mavrou A, et al. Clinical manifestations in 17 Greek patients with Goldenhar syndrome. Genet Couns. 2006;17:359–70.
Engiz O, Balci S, Unsal M, et al. 31 cases with oculoauriculovertebral dysplasia (Goldenhar syndrome): clinical, neuroradiologic, audiologic and cytogenetic findings. Genet Couns. 2007;3:277–88.
Internet
www.amyloidosis.org: Amyloidosis Foundation
www.eular.org: The European League Against Rheumatism
www.lupus.org: Lupus Foundation of America
www.rheumatology.org: American College of Rheumatology
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2014 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Safatle-Ribeiro, A., Gay, G., Barth, E., Keuchel, M. (2014). Involvement of the Small Intestine in Systemic Diseases. In: Keuchel, M., Hagenmüller, F., Tajiri, H. (eds) Video Capsule Endoscopy. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-44062-9_29
Download citation
DOI: https://doi.org/10.1007/978-3-662-44062-9_29
Published:
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-662-44061-2
Online ISBN: 978-3-662-44062-9
eBook Packages: MedicineMedicine (R0)