Abstract
Medication-related osteonecrosis of the jaw and phosphorous necrosis are strikingly similar. Phosphorous necrosis (phossy jaw) was caused by close contact with yellow phosphorous. In the nineteenth century, the knowledge concerning cause and prevention of osteonecrosis was astonishingly accurate. Rules concerning prevention and treatment were similar to those of our days. The Bern convention banned the use of yellow phosphorous. In the following decades, the disease gradually disappeared from common knowledge, until Robert Marx described the first modern bisphosphonate-related osteonecrosis of the jaw in 2003.
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Hoefert, S., Hoefert, C.S., Widmann, M. (2015). History of Osteonecrosis of the Jaw. In: Otto, S. (eds) Medication-Related Osteonecrosis of the Jaws. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-43733-9_19
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DOI: https://doi.org/10.1007/978-3-662-43733-9_19
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